Remodeling tumor immune microenvironment (TIME) for glioma therapy using multi-targeting liposomal codelivery

A multicenter phase II study of temozolomide plus disulfiram and copper for recurrent temozolomide-resistant glioblastoma

(2019) Jiayi Huang et al.   JOURNAL OF NEURO-ONCOLOGY

Dual-targeting biomimetic delivery for anti-glioma activity via remodeling the tumor microenvironment and directing macrophage-mediated immunotherapy

(2018) Pengfei Zhao et al.   Chemical Science

mTOR Pathways in Cancer and Autophagy

(2018) Mathieu Paquette et al.   Cancers

Role of mTOR Signaling in Tumor Microenvironment: An Overview

(2018) Fabiana Conciatori et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Natural killer cells induce distinct modes of cancer cell death: Discrimination, quantification and modulation of apoptosis, necrosis and mixed forms

(2018) Christian S Backes et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Antiglioma via regulating oxidative stress and remodeling tumor-associated macrophage using lactoferrin-mediated biomimetic codelivery of simvastatin/fenretinide

(2018) Xiaopeng Mo et al.   JOURNAL OF CONTROLLED RELEASE

mTORC1 and mTORC2 as regulators of cell metabolism in immunity

(2017) Monika Linke et al.   FEBS LETTERS

Immune microenvironment of gliomas

(2017) Anna Gieryng et al.   LABORATORY INVESTIGATION

HSP90 promotes cell glycolysis, proliferation and inhibits apoptosis by regulating PKM2 abundance via Thr-328 phosphorylation in hepatocellular carcinoma

(2017) Qiuran Xu et al.   Molecular Cancer

Alcohol-abuse drug disulfiram targets cancer via p97 segregase adaptor NPL4

(2017) Zdenek Skrott et al.   NATURE

CBTRUS Statistical Report: Primary brain and other central nervous system tumors diagnosed in the United States in 2010–2014

(2017) Quinn T Ostrom et al.   NEURO-ONCOLOGY

OS10.3 Randomized Phase 3 Study Evaluating the Efficacy and Safety of Nivolumab vs Bevacizumab in Patients With Recurrent Glioblastoma: CheckMate 143

(2017) D. A. Reardon et al.   NEURO-ONCOLOGY

Human and nonhuman primate meninges harbor lymphatic vessels that can be visualized noninvasively by MRI

(2017) Martina Absinta et al.   eLife

Immune microenvironment of experimental rat C6 gliomas resembles human glioblastomas

(2017) Anna Gieryng et al.   Scientific Reports

Chitosan thermogels for local expansion and delivery of tumor-specific T lymphocytes towards enhanced cancer immunotherapies

(2016) Anne Monette et al.   BIOMATERIALS

Disulfiram when Combined with Copper Enhances the Therapeutic Effects of Temozolomide for the Treatment of Glioblastoma

(2016) X. Lun et al.   CLINICAL CANCER RESEARCH

M2-polarized and tumor-associated macrophages alter NK cell phenotype and function in a contact-dependent manner

(2016) Tamara Krneta et al.   JOURNAL OF LEUKOCYTE BIOLOGY

The role of microglia and macrophages in glioma maintenance and progression

(2016) Dolores Hambardzumyan et al.   NATURE NEUROSCIENCE

AD-Peptide Ligand of Nicotine Acetylcholine Receptors for Brain-Targeted Drug Delivery

(2015) Xiaoli Wei et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Non-neuronal cholinergic system in regulation of immune function with a focus on α7 nAChRs

(2015) Koichiro Kawashima et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Structural and functional features of central nervous system lymphatic vessels

(2015) Antoine Louveau et al.   NATURE

Metabolic reprogramming in glioblastoma: the influence of cancer metabolism on epigenetics and unanswered questions

(2015) Sameer Agnihotri et al.   NEURO-ONCOLOGY

The nicotinic cholinergic system function in the human brain

(2015) Frauke Nees   NEUROPHARMACOLOGY

The metabolic checkpoint kinase mTOR is essential for IL-15 signaling during the development and activation of NK cells

(2014) Antoine Marçais et al.   NATURE IMMUNOLOGY

TSC1 controls macrophage polarization to prevent inflammatory disease

(2014) Linnan Zhu et al.   Nature Communications

Regulation of the pentose phosphate pathway in cancer

(2014) Peng Jiang et al.   Protein & Cell

Tandutinib Inhibits the Akt/mTOR Signaling Pathway to Inhibit Colon Cancer Growth

(2013) S. Ponnurangam et al.   MOLECULAR CANCER THERAPEUTICS

Erratum: Corrigendum: Comprehensive genomic characterization defines human glioblastoma genes and core pathways

(2013) The Cancer Genome Atlas Research Network   NATURE

Metabolic Reprogramming: A Cancer Hallmark Even Warburg Did Not Anticipate

(2012) Patrick S. Ward et al.   CANCER CELL

Macrophage-Induced Tumor Angiogenesis Is Regulated by the TSC2-mTOR Pathway

(2012) W. Chen et al.   CANCER RESEARCH

Resveratrol induces apoptosis via ROS-triggered autophagy in human colon cancer cells

(2012) HISANORI MIKI et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Lactate: A Metabolic Key Player in Cancer

(2011) F. Hirschhaeuser et al.   CANCER RESEARCH

The Beclin 1 network regulates autophagy and apoptosis

(2011) R Kang et al.   CELL DEATH AND DIFFERENTIATION

Myeloid-derived suppressor cell accumulation and function in patients with newly diagnosed glioblastoma

(2011) B. Raychaudhuri et al.   NEURO-ONCOLOGY

Honokiol-mediated Inhibition of PI3K/mTOR Pathway

(2009) Courtney Crane et al.   JOURNAL OF IMMUNOTHERAPY

Acetylcholine beyond neurons: the non-neuronal cholinergic system in humans

(2008) I Wessler et al.   BRITISH JOURNAL OF PHARMACOLOGY

Autophagy regulates selective HMGB1 release in tumor cells that are destined to die

(2008) J Thorburn et al.   CELL DEATH AND DIFFERENTIATION