Immune microenvironment of experimental rat C6 gliomas resembles human glioblastomas

Immune microenvironment of gliomas

(2017) Anna Gieryng et al.   LABORATORY INVESTIGATION

Targeting the tumor microenvironment: removing obstruction to anticancer immune responses and immunotherapy

(2016) J. M. Pitt et al.   ANNALS OF ONCOLOGY

MDSCs in cancer: Conceiving new prognostic and therapeutic targets

(2016) Francesco De Sanctis et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

CCL2 Produced by the Glioma Microenvironment Is Essential for the Recruitment of Regulatory T Cells and Myeloid-Derived Suppressor Cells

(2016) Alan L. Chang et al.   CANCER RESEARCH

Human glioblastoma-associated microglia/monocytes express a distinct RNA profile compared to human control and murine samples

(2016) Frank Szulzewsky et al.   GLIA

Genomic Analysis of Immune Cell Infiltrates Across 11 Tumor Types

(2016) Michael D. Iglesia et al.   JNCI-Journal of the National Cancer Institute

Telomere profiles and tumor-associated macrophages with different immune signatures affect prognosis in glioblastoma

(2016) Noelyn A Hung et al.   MODERN PATHOLOGY

The role of microglia and macrophages in glioma maintenance and progression

(2016) Dolores Hambardzumyan et al.   NATURE NEUROSCIENCE

Genomic Analysis of Immune Cell Infiltrates Across 11 Tumor Types

(2016) Michael D. Iglesia et al.   JNCI-Journal of the National Cancer Institute

Design of a Phase I Clinical Trial to Evaluate M032, a Genetically Engineered HSV-1 Expressing IL-12, in Patients with Recurrent/Progressive Glioblastoma Multiforme, Anaplastic Astrocytoma, or Gliosarcoma

(2016) Daxa Patel et al.   Human Gene Therapy Clinical Development

Resident microglia rather than peripheral macrophages promote vascularization in brain tumors and are source of alternative pro-angiogenic factors

(2015) Susan Brandenburg et al.   ACTA NEUROPATHOLOGICA

Myeloid-derived suppressor cell impact on endogenous and adoptively transferred T cells

(2015) Ainhoa Arina et al.   CURRENT OPINION IN IMMUNOLOGY

Therapeutic administration of IL-15 superagonist complex ALT-803 leads to long-term survival and durable antitumor immune response in a murine glioblastoma model

(2015) Dimitrios Mathios et al.   INTERNATIONAL JOURNAL OF CANCER

Myeloid-derived suppressor cells in the tumor microenvironment: expect the unexpected

(2015) Douglas Marvel et al.   JOURNAL OF CLINICAL INVESTIGATION

The interaction of anticancer therapies with tumor-associated macrophages

(2015) Alberto Mantovani et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Myeloid derived suppressor cell infiltration of murine and human gliomas is associated with reduction of tumor infiltrating lymphocytes

(2015) Baisakhi Raychaudhuri et al.   JOURNAL OF NEURO-ONCOLOGY

IL-12 and IL-23 cytokines: from discovery to targeted therapies for immune-mediated inflammatory diseases

(2015) Michele W L Teng et al.   NATURE MEDICINE

CD4+T effector memory cell dysfunction is associated with the accumulation of granulocytic myeloid-derived suppressor cells in glioblastoma patients

(2015) Daniel Dubinski et al.   NEURO-ONCOLOGY

Glioma-Associated Microglia/Macrophages Display an Expression Profile Different from M1 and M2 Polarization and Highly Express Gpnmb and Spp1

(2015) Frank Szulzewsky et al.   PLoS One

Inhibitors of tissue transglutaminase

(2015) Jeffrey W. Keillor et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Down-regulation of IKKβ expression in glioma-infiltrating microglia/macrophages is associated with defective inflammatory/immune gene responses in glioblastoma

(2015) Jakub Mieczkowski et al.   Oncotarget

Macrophage Ablation Reduces M2-Like Populations and Jeopardizes Tumor Growth in a MAFIA-Based Glioma Model

(2015) Konrad Gabrusiewicz et al.   NEOPLASIA

High Expression of Ribonucleotide Reductase Subunit M2 Correlates with Poor Prognosis of Hepatocellular Carcinoma

(2014) Boin Lee et al.   Gut and Liver

Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines

(2014) Peter J. Murray et al.   IMMUNITY

CCR4 and its ligands: from bench to bedside

(2014) O. Yoshie et al.   INTERNATIONAL IMMUNOLOGY

Resident microglia, and not peripheral macrophages, are the main source of brain tumor mononuclear cells

(2014) Annett Müller et al.   INTERNATIONAL JOURNAL OF CANCER

Human Anti-Inflammatory Macrophages Induce Foxp3+GITR+CD25+ Regulatory T Cells, Which Suppress via Membrane-Bound TGF -1

(2014) N. D. L. Savage et al.   JOURNAL OF IMMUNOLOGY

Cyclin-dependent kinases

(2014) Marcos Malumbres   GENOME BIOLOGY

Pathway-Centric Integrative Analysis Identifies RRM2 as a Prognostic Marker in Breast Cancer Associated with Poor Survival and Tamoxifen Resistance

(2014) Nagireddy Putluri et al.   NEOPLASIA

Molecular definition of the pro-tumorigenic phenotype of glioma-activated microglia

(2013) Aleksandra Ellert-Miklaszewska et al.   GLIA

Phenotypic characterisation of immune cell infiltrates in testicular germ cell neoplasia

(2013) Tine Hvarness et al.   JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Stathmin 1 is involved in the highly proliferative phenotype of high-risk myelodysplastic syndromes and acute leukemia cells

(2013) João Agostinho Machado-Neto et al.   LEUKEMIA RESEARCH

Targeting Tregs in Malignant Brain Cancer: Overcoming IDO

(2013) Derek A. Wainwright et al.   Frontiers in Immunology

Circulating progenitor cells: a comparison of patients with glioblastoma or meningioma

(2012) George A. Alexiou et al.   ACTA NEUROLOGICA BELGICA

E2F7 and E2F8 promote angiogenesis through transcriptional activation of VEGFA in cooperation with HIF1

(2012) Bart G M W Weijts et al.   EMBO JOURNAL

A cyclin without cyclin-dependent kinases: cyclin F controls genome stability through ubiquitin-mediated proteolysis

(2012) Vincenzo D’Angiolella et al.   TRENDS IN CELL BIOLOGY

Effector T-Cell Infiltration Positively Impacts Survival of Glioblastoma Patients and Is Impaired by Tumor-Derived TGF- 

(2011) J. Lohr et al.   CLINICAL CANCER RESEARCH

Repo-Man Coordinates Chromosomal Reorganization with Nuclear Envelope Reassembly during Mitotic Exit

(2011) Paola Vagnarelli et al.   DEVELOPMENTAL CELL

CXCR3 in T cell function

(2011) Joanna R. Groom et al.   EXPERIMENTAL CELL RESEARCH

The brain tumor microenvironment

(2011) Nikki A. Charles et al.   GLIA

CXCR3 ligands: redundant, collaborative and antagonistic functions

(2011) Joanna R Groom et al.   IMMUNOLOGY AND CELL BIOLOGY

Adjuvant immunotherapy of C6 glioma in rats with pertussis toxin

(2011) Mario Orozco-Morales et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

LRRC4 inhibits the proliferation of human glioma cells by modulating the expression of STMN1 and microtubule polymerization

(2011) Rong Wang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

E2F7 represses a network of oscillating cell cycle genes to control S-phase progression

(2011) Bart Westendorp et al.   NUCLEIC ACIDS RESEARCH

Interferon-α-Conditioned Human Monocytes Combine a Th1-Orienting Attitude with the Induction of Autologous Th17 Responses: Role of IL-23 and IL-12

(2011) Stefano M. Santini et al.   PLoS One

Characteristics of the Alternative Phenotype of Microglia/Macrophages and its Modulation in Experimental Gliomas

(2011) Konrad Gabrusiewicz et al.   PLoS One

CXCR6/CXCL16 functions as a regulator in metastasis and progression of cancer

(2010) Ling Deng et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Exciting New Advances in Neuro-Oncology: The Avenue to a Cure for Malignant Glioma

(2010) E. G. Van Meir et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1

(2010) Roel G.W. Verhaak et al.   CANCER CELL

Glutamate and the biology of gliomas

(2010) John de Groot et al.   GLIA

Glioma morphology and tumor-induced vascular alterations revealed in seven rodent glioma models by in vivo magnetic resonance imaging and angiography

(2010) Sabrina Doblas et al.   JOURNAL OF MAGNETIC RESONANCE IMAGING

How kinesin motor proteins drive mitotic spindle function: Lessons from molecular assays

(2010) Linda Wordeman   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Rat brain tumor models in experimental neuro-oncology: the C6, 9L, T9, RG2, F98, BT4C, RT-2 and CNS-1 gliomas

(2009) Rolf F. Barth et al.   JOURNAL OF NEURO-ONCOLOGY

Flow cytometry and in vitro analysis of human glioma–associated macrophages

(2009) Ian F. Parney et al.   JOURNAL OF NEUROSURGERY

Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial

(2009) Roger Stupp et al.   LANCET ONCOLOGY

Gliomas induce and exploit microglial MT1-MMP expression for tumor expansion

(2009) D. S. Markovic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synergistic Function of E2F7 and E2F8 Is Essential for Cell Survival and Embryonic Development

(2008) Jing Li et al.   DEVELOPMENTAL CELL

Signalling, inflammation and arthritis: Crossed signals: the role of interleukin-15 and -18 in autoimmunity

(2008) H. P. Carroll et al.   RHEUMATOLOGY