Dual-targeting biomimetic delivery for anti-glioma activity via remodeling the tumor microenvironment and directing macrophage-mediated immunotherapy

Prognostic significance of tumor-associated macrophages in ovarian cancer: A meta-analysis

(2017) Xia Yuan et al.   GYNECOLOGIC ONCOLOGY

PD-1 expression by tumour-associated macrophages inhibits phagocytosis and tumour immunity

(2017) Sydney R. Gordon et al.   NATURE

OS10.3 Randomized Phase 3 Study Evaluating the Efficacy and Safety of Nivolumab vs Bevacizumab in Patients With Recurrent Glioblastoma: CheckMate 143

(2017) D. A. Reardon et al.   NEURO-ONCOLOGY

Lipoprotein-biomimetic nanostructure enables efficient targeting delivery of siRNA to Ras-activated glioblastoma cells via macropinocytosis

(2017) Jia-Lin Huang et al.   Nature Communications

Human and nonhuman primate meninges harbor lymphatic vessels that can be visualized noninvasively by MRI

(2017) Martina Absinta et al.   eLife

CD163+CD204+ tumor-associated macrophages contribute to T cell regulation via interleukin-10 and PD-L1 production in oral squamous cell carcinoma

(2017) Keigo Kubota et al.   Scientific Reports

Dual-Targeting Magnetic PLGA Nanoparticles for Codelivery of Paclitaxel and Curcumin for Brain Tumor Therapy

(2016) Yanna Cui et al.   ACS Applied Materials & Interfaces

Blood–Brain-Barrier-Penetrating Albumin Nanoparticles for Biomimetic Drug Delivery via Albumin-Binding Protein Pathways for Antiglioma Therapy

(2016) Tingting Lin et al.   ACS Nano

A Breakthrough: Macrophage-Directed Cancer Immunotherapy

(2016) C. D. Mills et al.   CANCER RESEARCH

The role of microglia and macrophages in glioma maintenance and progression

(2016) Dolores Hambardzumyan et al.   NATURE NEUROSCIENCE

Pharmacokinetic strategies to improve drug penetration and entrapment within solid tumors

(2015) Ahmed M. Al-Abd et al.   JOURNAL OF CONTROLLED RELEASE

Disulfiram (DSF) acts as a copper ionophore to induce copper-dependent oxidative stress and mediate anti-tumor efficacy in inflammatory breast cancer

(2015) Jennifer L. Allensworth et al.   Molecular Oncology

Structural and functional features of central nervous system lymphatic vessels

(2015) Antoine Louveau et al.   NATURE

Central nervous system myeloid cells as drug targets: current status and translational challenges

(2015) Knut Biber et al.   NATURE REVIEWS DRUG DISCOVERY

Concise Review: Bullseye: Targeting Cancer Stem Cells to Improve the Treatment of Gliomas by Repurposing Disulfiram

(2015) Joanna Triscott et al.   STEM CELLS

Regorafenib impairs mitochondrial functions, activates AMP-activated protein kinase, induces autophagy, and causes rat hepatocyte necrosis

(2015) Zuquan Weng et al.   TOXICOLOGY

A Prodrug-type, MMP-2-targeting Nanoprobe for Tumor Detection and Imaging

(2015) Yaping Wang et al.   Theranostics

Immunosuppressive Mechanisms of Malignant Gliomas: Parallels at Non-CNS Sites

(2015) Powell Perng et al.   Frontiers in Oncology

Paclitaxel loaded liposomes decorated with a multifunctional tandem peptide for glioma targeting

(2014) Yayuan Liu et al.   BIOMATERIALS

Plasticity of Macrophage Function during Tumor Progression: Regulation by Distinct Molecular Mechanisms

(2014) S. K. Biswas et al.   JOURNAL OF IMMUNOLOGY

Unraveling the mysteries of serum albumin—more than just a serum protein

(2014) Angelica M. Merlot et al.   Frontiers in Physiology

Emerging role of tumor-associated macrophages as therapeutic targets in patients with metastatic renal cell carcinoma

(2013) Matteo Santoni et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Immune-based mechanisms of cytotoxic chemotherapy: implications for the design of novel and rationale-based combined treatments against cancer

(2013) L Bracci et al.   CELL DEATH AND DIFFERENTIATION

Regorafenib Inhibits Growth, Angiogenesis, and Metastasis in a Highly Aggressive, Orthotopic Colon Cancer Model

(2013) L. Abou-Elkacem et al.   MOLECULAR CANCER THERAPEUTICS

Microenvironmental regulation of tumor progression and metastasis

(2013) Daniela F Quail et al.   NATURE MEDICINE

CSF-1R inhibition alters macrophage polarization and blocks glioma progression

(2013) Stephanie M Pyonteck et al.   NATURE MEDICINE

Macrophage-Induced Tumor Angiogenesis Is Regulated by the TSC2-mTOR Pathway

(2012) W. Chen et al.   CANCER RESEARCH

Polymer nanoparticulate drug delivery and combination cancer therapy

(2012) Pengxiao Cao et al.   Future Oncology

IFN-γ, IL-17 and TGF-β involvement in shaping the tumor microenvironment: The significance of modulating such cytokines in treating malignant solid tumors

(2011) Heba A Alshaker et al.   Cancer Cell International

Immune microenvironments in solid tumors: new targets for therapy

(2011) S. L. Shiao et al.   GENES & DEVELOPMENT

Protein alterations associated with temozolomide resistance in subclones of human glioblastoma cell lines

(2011) Stella Sun et al.   JOURNAL OF NEURO-ONCOLOGY

Regorafenib (BAY 73-4506): A new oral multikinase inhibitor of angiogenic, stromal and oncogenic receptor tyrosine kinases with potent preclinical antitumor activity

(2010) Scott M. Wilhelm et al.   INTERNATIONAL JOURNAL OF CANCER

Inhibition of endogenous SPARC enhances pancreatic cancer cell growth: modulation by FGFR1-III isoform expression

(2009) G Chen et al.   BRITISH JOURNAL OF CANCER

Dual-targeting daunorubicin liposomes improve the therapeutic efficacy of brain glioma in animals

(2009) Xue Ying et al.   JOURNAL OF CONTROLLED RELEASE