The Two-Component Response Regulator Ssk1 and the Mitogen-Activated Protein Kinase Hog1 Control Antifungal Drug Resistance and Cell Wall Architecture of Candida auris

Candida auris Isolates Resistant to Three Classes of Antifungal Medications — New York, 2019

(2020) Belinda Ostrowsky et al.   MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT

Candida auris Forms High-Burden Biofilms in Skin Niche Conditions and on Porcine Skin

(2020) Mark V. Horton et al.   mSphere

Tracing the Evolutionary History and Global Expansion of Candida auris Using Population Genomic Analyses

(2020) Nancy A. Chow et al.   mBio

Transcriptional and functional insights into the host immune response against the emerging fungal pathogen Candida auris

(2020) Mariolina Bruno et al.   Nature Microbiology

Twenty Years of the SENTRY Antifungal Surveillance Program: Results for Candida Species From 1997–2016

(2019) Michael A Pfaller et al.   Open Forum Infectious Diseases

Circuit diversification in a biofilm regulatory network

(2019) Manning Y. Huang et al.   PLoS Pathogens

On the Emergence of Candida auris: Climate Change, Azoles, Swamps, and Birds

(2019) Arturo Casadevall et al.   mBio

The Fungal Histone Acetyl Transferase Gcn5 Controls Virulence of the Human Pathogen Candida albicans through Multiple Pathways

(2019) Raju Shivarathri et al.   Scientific Reports

Stress-Activated Protein Kinases in Human Fungal Pathogens

(2019) Alison M. Day et al.   Frontiers in Cellular and Infection Microbiology

Fungal Cell Wall: Emerging Antifungals and Drug Resistance

(2019) Soraia L. Lima et al.   Frontiers in Microbiology

The MAPK Hog1 mediates the response to amphotericin B in Candida albicans

(2019) José Pedro Guirao-Abad et al.   FUNGAL GENETICS AND BIOLOGY

Understanding Echinocandin Resistance in the Emerging Pathogen Candida auris

(2018) Milena Kordalewska et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

A multicentre study of antifungal susceptibility patterns among 350 Candida auris isolates (2009–17) in India: role of the ERG11 and FKS1 genes in azole and echinocandin resistance

(2018) Anuradha Chowdhary et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Dynamic Fungal Cell Wall Architecture in Stress Adaptation and Immune Evasion

(2018) Alex Hopke et al.   TRENDS IN MICROBIOLOGY

Candida auris: a global fungal public health threat

(2018) Jacques F Meis et al.   LANCET INFECTIOUS DISEASES

Genomic insights into multidrug-resistance, mating and virulence in Candida auris and related emerging species

(2018) José F. Muñoz et al.   Nature Communications

Hog1 Regulates Stress Tolerance and Virulence in the Emerging Fungal Pathogen Candida auris

(2018) Alison M. Day et al.   mSphere

The Stress-Sensing TORC2 Complex Activates Yeast AGC-Family Protein Kinase Ypk1 at Multiple Novel Sites

(2017) Kristin L. Leskoske et al.   GENETICS

Candida auris: A rapidly emerging cause of hospital-acquired multidrug-resistant fungal infections globally

(2017) Anuradha Chowdhary et al.   PLoS Pathogens

Antifungal Therapy: New Advances in the Understanding and Treatment of Mycosis

(2017) Liliana Scorzoni et al.   Frontiers in Microbiology

The Stress-Sensing TORC2 Complex Activates Yeast AGC-Family Protein Kinase Ypk1 at Multiple Novel Sites

(2017) Kristin L. Leskoske et al.   GENETICS

Simultaneous Emergence of Multidrug-ResistantCandida aurison 3 Continents Confirmed by Whole-Genome Sequencing and Epidemiological Analyses

(2016) Shawn R. Lockhart et al.   CLINICAL INFECTIOUS DISEASES

A global genetic interaction network maps a wiring diagram of cellular function

(2016) M. Costanzo et al.   SCIENCE

A Case for Two-Component Signaling Systems As Antifungal Drug Targets

(2015) Erika Shor et al.   PLoS Pathogens

The Candida albicans Histone Acetyltransferase Hat1 Regulates Stress Resistance and Virulence via Distinct Chromatin Assembly Pathways

(2015) Michael Tscherner et al.   PLoS Pathogens

Down-regulation of TORC2-Ypk1 signaling promotes MAPK-independent survival under hyperosmotic stress

(2015) Alexander Muir et al.   eLife

Crosstalk and the evolution of specificity in two-component signaling

(2014) M. A. Rowland et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Systematic Phenotyping of a Large-Scale Candida glabrata Deletion Collection Reveals Novel Antifungal Tolerance Genes

(2014) Tobias Schwarzmüller et al.   PLoS Pathogens

Striking a balance: fungal commensalism versus pathogenesis

(2013) Iliyan D Iliev et al.   CURRENT OPINION IN MICROBIOLOGY

Stress adaptation in a pathogenic fungus

(2013) A. J. P. Brown et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Fitness Trade-offs Restrict the Evolution of Resistance to Amphotericin B

(2013) Benjamin Matteson Vincent et al.   PLOS BIOLOGY

Differential Adaptation of Candida albicans In Vivo Modulates Immune Recognition by Dectin-1

(2013) Mohlopheni J. Marakalala et al.   PLoS Pathogens

Systems biology of host–fungus interactions: turning complexity into simplicity

(2012) Lanay Tierney et al.   CURRENT OPINION IN MICROBIOLOGY

C-type lectin receptors orchestrate antifungal immunity

(2012) Sarah E Hardison et al.   NATURE IMMUNOLOGY

Amphotericin primarily kills yeast by simply binding ergosterol

(2012) K. C. Gray et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hidden Killers: Human Fungal Infections

(2012) G. D. Brown et al.   Science Translational Medicine

It only takes one to do many jobs: Amphotericin B as antifungal and immunomodulatory drug

(2012) Ana C. Mesa-Arango et al.   Frontiers in Microbiology

Efg1 Controls Caspofungin-Induced Cell Aggregation of Candida albicans through the Adhesin Als1

(2011) Christa Gregori et al.   EUKARYOTIC CELL

Candida albicans SRR1 , a Putative Two-Component Response Regulator Gene, Is Required for Stress Adaptation, Morphogenesis, and Virulence

(2011) Chirayu Desai et al.   EUKARYOTIC CELL

Regulation of Cell Wall Biogenesis inSaccharomyces cerevisiae: The Cell Wall Integrity Signaling Pathway

(2011) David E. Levin   GENETICS

Protein kinase Ypk1 phosphorylates regulatory proteins Orm1 and Orm2 to control sphingolipid homeostasis in Saccharomyces cerevisiae

(2011) F. M. Roelants et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Our Paths Might Cross: the Role of the Fungal Cell Wall Integrity Pathway in Stress Response and Cross Talk with Other Stress Response Pathways

(2009) Beth Burgwyn Fuchs et al.   EUKARYOTIC CELL

Contributions of the Response Regulators Ssk1p and Skn7p in the Pseudohyphal Development, Stress Adaptation, and Drug Sensitivity of the Opportunistic YeastCandida lusitaniae

(2008) Gwenaël Ruprich-Robert et al.   EUKARYOTIC CELL

Transcriptional profiling of theCandida albicansSsk1p receiver domain point mutants and their virulence

(2008) Veena Menon et al.   FEMS YEAST RESEARCH