Broad TCR repertoire and diverse structural solutions for recognition of an immunodominant CD8+ T cell epitope

Abundant cytomegalovirus (CMV) reactive clonotypes in the CD8+T cell receptor alpha repertoire following allogeneic transplantation

(2016) C. S. Link et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Molecular basis for universal HLA-A*0201–restricted CD8+T-cell immunity against influenza viruses

(2016) Sophie A. Valkenburg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Naive CD8+ T-cell precursors display structured TCR repertoires and composite antigen-driven selection dynamics

(2015) Michelle A Neller et al.   IMMUNOLOGY AND CELL BIOLOGY

Structural Basis for Clonal Diversity of the Public T Cell Response to a Dominant Human Cytomegalovirus Epitope

(2015) Xinbo Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Narrowing of Human Influenza A Virus-Specific T Cell Receptor α and β Repertoires with Increasing Age

(2015) Anna Gil et al.   JOURNAL OF VIROLOGY

Physical detection of influenza A epitopes identifies a stealth subset on human lung epithelium evading natural CD8 immunity

(2015) Derin B. Keskin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Computational analysis of stochastic heterogeneity in PCR amplification efficiency revealed by single molecule barcoding

(2015) Katharine Best et al.   Scientific Reports

Diversity index of mucosal resident T lymphocyte repertoire predicts clinical prognosis in gastric cancer

(2015) Qingzhu Jia et al.   OncoImmunology

Multiple Glycines in TCR  -Chains Determine Clonally Diverse Nature of Human T Cell Memory to Influenza A Virus

(2014) Y. N. Naumov et al.   JOURNAL OF IMMUNOLOGY

Molecular Basis of a Dominant T Cell Response to an HIV Reverse Transcriptase 8-mer Epitope Presented by the Protective Allele HLA-B*51:01

(2014) C. Motozono et al.   JOURNAL OF IMMUNOLOGY

Superimposed Epitopes Restricted by the Same HLA Molecule Drive Distinct HIV-Specific CD8+ T Cell Repertoires

(2014) X. Sun et al.   JOURNAL OF IMMUNOLOGY

The Immunodominant Influenza A Virus M158-66 Cytotoxic T Lymphocyte Epitope Exhibits Degenerate Class I Major Histocompatibility Complex Restriction in Humans

(2014) J. A. L. Choo et al.   JOURNAL OF VIROLOGY

Complex T-Cell Receptor Repertoire Dynamics Underlie the CD8+T-Cell Response to HIV-1

(2014) Ana I. Costa et al.   JOURNAL OF VIROLOGY

Regulatory T Cells Resist Virus Infection-Induced Apoptosis

(2014) Jenny W. Che et al.   JOURNAL OF VIROLOGY

Linking T-cell receptor sequence to functional phenotype at the single-cell level

(2014) Arnold Han et al.   NATURE BIOTECHNOLOGY

T cell mediated immunity to influenza: mechanisms of viral control

(2014) Nicole L. La Gruta et al.   TRENDS IN IMMUNOLOGY

Highly Divergent T-cell Receptor Binding Modes Underlie Specific Recognition of a Bulged Viral Peptide bound to a Human Leukocyte Antigen Class I Molecule

(2013) Yu Chih Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

T-cell Receptor Specificity Maintained by Altered Thermodynamics

(2013) Florian Madura et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A small jab – a big effect: nonspecific immunomodulation by vaccines

(2013) Christine S. Benn et al.   TRENDS IN IMMUNOLOGY

Using synthetic templates to design an unbiased multiplex PCR assay

(2013) Christopher S. Carlson et al.   Nature Communications

Sequence analysis of T-cell repertoires in health and disease

(2013) Daniel J Woodsworth et al.   Genome Medicine

Collaboration gets the most out of software

(2013) Andrew Morin et al.   eLife

Next generation sequencing for TCR repertoire profiling: Platform-specific features and correction algorithms

(2012) Dmitry A. Bolotin et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

A structural voyage toward an understanding of the MHC-I-restricted immune response: lessons learned and much to be learned

(2012) Stephanie Gras et al.   IMMUNOLOGICAL REVIEWS

The design and proof of concept for a CD8+ T cell-based vaccine inducing cross-subtype protection against influenza A virus

(2012) Amabel C L Tan et al.   IMMUNOLOGY AND CELL BIOLOGY

CD8+ TCR Repertoire Formation Is Guided Primarily by the Peptide Component of the Antigenic Complex

(2012) D. Koning et al.   JOURNAL OF IMMUNOLOGY

The Role of Naive T Cell Precursor Frequency and Recruitment in Dictating Immune Response Magnitude

(2012) M. K. Jenkins et al.   JOURNAL OF IMMUNOLOGY

Deep Sequencing of Antiviral T-Cell Responses to HCMV and EBV in Humans Reveals a Stable Repertoire That Is Maintained for Many Years

(2012) P. L. Klarenbeek et al.   PLoS Pathogens

iMOSFLM: a new graphical interface for diffraction-image processing withMOSFLM

(2011) T. Geoff G. Battye et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Overview of theCCP4 suite and current developments

(2011) Martyn D. Winn et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Heterologous immunity: Immunopathology, autoimmunity and protection during viral infections

(2011) Liisa K. Selin et al.   AUTOIMMUNITY

Structural and biophysical determinants of αβ T-cell antigen recognition

(2011) John S. Bridgeman et al.   IMMUNOLOGY

Naive T Cell Repertoire Skewing in HLA-A2 Individuals by a Specialized Rearrangement Mechanism Results in Public Memory Clonotypes

(2011) M. Yassai et al.   JOURNAL OF IMMUNOLOGY

A Structural Basis for Varied    TCR Usage against an Immunodominant EBV Antigen Restricted to a HLA-B8 Molecule

(2011) S. Gras et al.   JOURNAL OF IMMUNOLOGY

Precursor Frequency and Competition Dictate the HLA-A2-Restricted CD8+ T Cell Responses to Influenza A Infection and Vaccination in HLA-A2.1 Transgenic Mice

(2011) A. C. L. Tan et al.   JOURNAL OF IMMUNOLOGY

GagCM9-Specific CD8+ T Cells Expressing Limited Public TCR Clonotypes Do Not Suppress SIV Replication In Vivo

(2011) Lara Vojnov et al.   PLoS One

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Broad Cross-Reactive TCR Repertoires Recognizing Dissimilar Epstein-Barr and Influenza A Virus Epitopes

(2010) S. C. Clute et al.   JOURNAL OF IMMUNOLOGY

T Cell-Mediated Protection against Lethal 2009 Pandemic H1N1 Influenza Virus Infection in a Mouse Model

(2010) H. Guo et al.   JOURNAL OF VIROLOGY

Comprehensive assessment of T-cell receptor  -chain diversity in    T cells

(2009) H. S. Robins et al.   BLOOD

A Single TCR -Chain with Dominant Peptide Recognition in the Allorestricted HER2/neu-Specific T Cell Repertoire

(2009) X. Liang et al.   JOURNAL OF IMMUNOLOGY

Production of soluble αβ T-cell receptor heterodimers suitable for biophysical analysis of ligand binding

(2009) Benjamin E. Willcoj et al.   PROTEIN SCIENCE

Crossreactive T Cells Spotlight the Germline Rules for αβ T Cell-Receptor Interactions with MHC Molecules

(2008) Shaodong Dai et al.   IMMUNITY

The Structural Dynamics and Energetics of an Immunodominant T Cell Receptor Are Programmed by Its Vβ Domain

(2008) Jeffrey Ishizuka et al.   IMMUNITY

Age-associated decline in T cell repertoire diversity leads to holes in the repertoire and impaired immunity to influenza virus

(2008) Eric J. Yager et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Immunomic Analysis of the Repertoire of T-Cell Specificities for Influenza A Virus in Humans

(2008) E. Assarsson et al.   JOURNAL OF VIROLOGY

IMGT/V-QUEST: the highly customized and integrated system for IG and TR standardized V-J and V-D-J sequence analysis

(2008) X. Brochet et al.   NUCLEIC ACIDS RESEARCH