Gadolinium Oxide Nanoparticles Induce Toxicity in Human Endothelial HUVECs via Lipid Peroxidation, Mitochondrial Dysfunction and Autophagy Modulation

Gadolinium-Based Nanoparticles Can Overcome the Radioresistance of Head and Neck Squamous Cell Carcinoma Through the Induction of Autophagy

(2020) S. Simonet et al.   Journal of Biomedical Nanotechnology

High Surface Reactivity and Biocompatibility of Y2O3 NPs in Human MCF-7 Epithelial and HT-1080 FibroBlast Cells

(2020) Mohd Javed Akhtar et al.   MOLECULES

Investigation of potential adverse central nervous system effects after long term oral administration of gadolinium in mice

(2020) Dominik Nörenberg et al.   PLoS One

Molecular mechanisms of methylglyoxal-induced aortic endothelial dysfunction in human vascular endothelial cells

(2020) Jae Hyuk Lee et al.   Cell Death & Disease

Cytotoxicity, dose-enhancement and radiosensitization of glioblastoma cells with rare earth nanoparticles

(2019) Victor M. Lu et al.   Artificial Cells Nanomedicine and Biotechnology

Two distinct cellular pathways leading to endothelial cell cytotoxicity by silica nanoparticle size

(2019) Kyungmin Lee et al.   JOURNAL OF NANOBIOTECHNOLOGY

Toxicological assessment of anthropogenic Gadolinium in seawater: Biochemical effects in mussels Mytilus galloprovincialis

(2019) Bruno Henriques et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Amphiphilic nanogels: influence of surface hydrophobicity on protein corona, biocompatibility and cellular uptake

(2019) Tony Bewersdorff et al.   International Journal of Nanomedicine

Mitochondrial dysfunction, autophagy stimulation and non-apoptotic cell death caused by nitric oxide-inducing Pt-coated Au nanoparticle in human lung carcinoma cells

(2019) Mohd Javed Akhtar et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Modulating autophagy in cancer therapy: Advancements and challenges for cancer cell death sensitization

(2018) Punya Bhat et al.   BIOCHEMICAL PHARMACOLOGY

Gadolinium as a new emerging contaminant of aquatic environments

(2018) Justyna Rogowska et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Necrotic, apoptotic and autophagic cell fates triggered by nanoparticles

(2018) Reza Mohammadinejad et al.   Autophagy

Challenges facing nanotoxicology and nanomedicine due to cellular diversity

(2018) Mohd Javed Akhtar et al.   CLINICA CHIMICA ACTA

Exposure of Macrophages to Low-Dose Gadolinium-Based Contrast Medium: Impact on Oxidative Stress and Cytokines Production

(2018) Te-I Weng et al.   Contrast Media & Molecular Imaging

Gadolinium tissue deposition in the periodontal ligament of mice with reduced renal function exposed to Gd-based contrast agents

(2018) Riccarda Delfino et al.   TOXICOLOGY LETTERS

Reactive oxygen species and cancer paradox: To promote or to suppress?

(2017) Sehamuddin Galadari et al.   FREE RADICAL BIOLOGY AND MEDICINE

Regulation of apoptosis through bcl-2/bax proteins expression and DNA damage by nano-sized gadolinium oxide

(2017) Saud Alarifi et al.   International Journal of Nanomedicine

Mesoporous silica nanoparticles trigger mitophagy in endothelial cells and perturb neuronal network activity in a size- and time-dependent manner

(2017) Antonina Orlando et al.   International Journal of Nanomedicine

The use of human umbilical vein endothelial cells (HUVECs) as an in vitro model to assess the toxicity of nanoparticles to endothelium: a review

(2017) Yi Cao et al.   JOURNAL OF APPLIED TOXICOLOGY

Gadolinium Deposition in Human Brain Tissues after Contrast-enhanced MR Imaging in Adult Patients without Intracranial Abnormalities

(2017) Robert J. McDonald et al.   RADIOLOGY

The presence of the gadolinium-based contrast agent depositions in the brain and symptoms of gadolinium neurotoxicity - A systematic review

(2017) Cyprian Olchowy et al.   PLoS One

Anti-cancerous effect of albumin coated silver nanoparticles on MDA-MB 231 human breast cancer cell line

(2017) Marzieh Azizi et al.   Scientific Reports

Gadolinium-based contrast agent toxicity: a review of known and proposed mechanisms

(2016) Moshe Rogosnitzky et al.   BIOMETALS

Autophagy in vascular endothelial cells

(2016) Fan Jiang   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Cytotoxicity, oxidative stress and inflammation induced by ZnO nanoparticles in endothelial cells: interaction with palmitate or lipopolysaccharide

(2016) Yu Gong et al.   JOURNAL OF APPLIED TOXICOLOGY

Development of Bifunctional Gadolinium-Labeled Superparamagnetic Nanoparticles (Gd-MnMEIO) for In Vivo MR Imaging of the Liver in an Animal Model

(2016) Yu-Ting Kuo et al.   PLoS One

Targeting the lysosome in cancer

(2015) Shengfu Piao et al.   Annals of the New York Academy of Sciences

Enhanced production of reactive oxygen species by gadolinium oxide nanoparticles under core–inner-shell excitation by proton or monochromatic X-ray irradiation: implication of the contribution from the interatomic de-excitation-mediated nanoradiator effect to dose enhancement

(2015) Seung-Jun Seo et al.   RADIATION AND ENVIRONMENTAL BIOPHYSICS

Intracranial Gadolinium Deposition after Contrast-enhanced MR Imaging

(2015) Robert J. McDonald et al.   RADIOLOGY

Gd2O3nanoparticles: size-dependent nuclear magnetic resonance

(2015) A. T. M. Anishur Rahman et al.   Contrast Media & Molecular Imaging

Interference in Autophagosome Fusion by Rare Earth Nanoparticles Disrupts Autophagic Flux and Regulation of an Interleukin-1β Producing Inflammasome

(2014) Ruibin Li et al.   ACS Nano

Targeted anticancer therapy: Overexpressed receptors and nanotechnology

(2014) Mohd Javed Akhtar et al.   CLINICA CHIMICA ACTA

Evaluation of acridine orange, LysoTracker Red, and quinacrine as fluorescent probes for long-term tracking of acidic vesicles

(2014) Agnieszka Pierzyńska-Mach et al.   CYTOMETRY PART A

Detection of radicals in single droplets of oil-in-water emulsions with the lipophilic fluorescent probe BODIPY665/676 and confocal laser scanning microscopy

(2014) Piret Raudsepp et al.   FREE RADICAL BIOLOGY AND MEDICINE

Cell-death assessment by fluorescent and nonfluorescent cytosolic and nuclear staining techniques

(2014) N. ATALE et al.   JOURNAL OF MICROSCOPY

A targeted approach to cancer imaging and therapy

(2014) Chun Li   NATURE MATERIALS

Toxic Effect of Silica Nanoparticles on Endothelial Cells through DNA Damage Response via Chk1-Dependent G2/M Checkpoint

(2013) Junchao Duan et al.   PLoS One

High Signal Intensity in the Dentate Nucleus and Globus Pallidus on Unenhanced T1-weighted MR Images: Relationship with Increasing Cumulative Dose of a Gadolinium-based Contrast Material

(2013) Tomonori Kanda et al.   RADIOLOGY

Monitoring autophagic flux by an improved tandem fluorescent-tagged LC3 (mTagRFP-mWasabi-LC3) reveals that high-dose rapamycin impairs autophagic flux in cancer cells

(2012) Cuihong Zhou et al.   Autophagy

Glutathione and modulation of cell apoptosis

(2012) Magdalena L. Circu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

DNA Surface Modified Gadolinium Phosphate Nanoparticles as MRI Contrast Agents

(2012) Matthieu F. Dumont et al.   BIOCONJUGATE CHEMISTRY

Zinc oxide nanoparticles selectively induce apoptosis in human cancer cells through reactive oxygen species

(2012) Maqusood Ahamed et al.   International Journal of Nanomedicine

Multifactorial determinants that govern nanoparticle uptake by human endothelial cells under flow

(2012) Adriele Prina-Mello et al.   International Journal of Nanomedicine

N-Acetylcysteine Protects Rats with Chronic Renal Failure from Gadolinium-Chelate Nephrotoxicity

(2012) Leonardo Victor Barbosa Pereira et al.   PLoS One

Apoptosis induction by silica nanoparticles mediated through reactive oxygen species in human liver cell line HepG2

(2012) Javed Ahmad et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Discrimination between primary necrosis and apoptosis by necrostatin-1 in Annexin V-positive/propidium iodide-negative cells

(2011) Hirofumi Sawai et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Autophagy, mitochondria and oxidative stress: cross-talk and redox signalling

(2011) Jisun Lee et al.   BIOCHEMICAL JOURNAL

Programmed necrosis induced by asbestos in human mesothelial cells causes high-mobility group box 1 protein release and resultant inflammation

(2010) Haining Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of autophagy by ROS: physiology and pathology

(2010) Ruth Scherz-Shouval et al.   TRENDS IN BIOCHEMICAL SCIENCES

Upstream reactive oxidative species (ROS) signals in exogenous oxidative stress-induced mitochondrial dysfunction

(2009) Min Lu et al.   CELL BIOLOGY INTERNATIONAL

Understanding biophysicochemical interactions at the nano–bio interface

(2009) Andre E. Nel et al.   NATURE MATERIALS

Mesothelioma: Do asbestos and carbon nanotubes pose the same health risk?

(2009) Marie-Claude F Jaurand et al.   Particle and Fibre Toxicology