A targeted approach to cancer imaging and therapy

Imaging macrophages with nanoparticles

(2014) Ralph Weissleder et al.   NATURE MATERIALS

In Vivo Tumor Targeting and Image-Guided Drug Delivery with Antibody-Conjugated, Radiolabeled Mesoporous Silica Nanoparticles

(2013) Feng Chen et al.   ACS Nano

Periodicity in tumor vasculature targeting kinetics of ligand-functionalized nanoparticles studied by dynamic contrast enhanced magnetic resonance imaging and intravital microscopy

(2013) Sjoerd Hak et al.   ANGIOGENESIS

Specific lipase-responsive polymer-coated gadolinium nanoparticles for MR imaging of early acute pancreatitis

(2013) Hong-Wu Zhang et al.   BIOMATERIALS

Liposomal doxorubicin plus radiofrequency ablation for complete necrosis of a hepatocellular carcinoma

(2013) C.W. Hong et al.   Current Oncology

Novel approaches to the development of tyrosine kinase inhibitors and their role in the fight against cancer

(2013) Adriana Zámečníkova   Expert Opinion on Drug Discovery

Generalised polynomial chaos-based uncertainty quantification for planning MRgLITT procedures

(2013) Samuel J. Fahrenholtz et al.   INTERNATIONAL JOURNAL OF HYPERTHERMIA

High-sensitivity, real-time, ratiometric imaging of surface-enhanced Raman scattering nanoparticles with a clinically translatable Raman endoscope device

(2013) Ellis Garai et al.   JOURNAL OF BIOMEDICAL OPTICS

In vitro and in vivo mapping of drug release after laser ablation thermal therapy with doxorubicin-loaded hollow gold nanoshells using fluorescence and photoacoustic imaging

(2013) Hannah J. Lee et al.   JOURNAL OF CONTROLLED RELEASE

Nonpolymeric Surface-Coated Iron Oxide Nanoparticles for In Vivo Molecular Imaging: Biodegradation, Biocompatibility, and Multiplatform

(2013) C.-M. Lee et al.   JOURNAL OF NUCLEAR MEDICINE

Noninvasive Fluorescence Resonance Energy Transfer Imaging of in Vivo Premature Drug Release from Polymeric Nanoparticles

(2013) Peng Zou et al.   MOLECULAR PHARMACEUTICS

Optimized multimodal nanoplatforms for targeting αvβ3 integrins

(2013) Julie Bolley et al.   Nanoscale

Strategies for advancing cancer nanomedicine

(2013) Vikash P. Chauhan et al.   NATURE MATERIALS

Roadblocks to translational advances on metastasis research

(2013) Thomas Brabletz et al.   NATURE MEDICINE

In vivo magnetic resonance imaging of hyperpolarized silicon particles

(2013) M. C. Cassidy et al.   Nature Nanotechnology

Molecular MR Imaging of Neovascular Progression in the Vx2 Tumor with αvβ3-Targeted Paramagnetic Nanoparticles

(2013) Anne H. Schmieder et al.   RADIOLOGY

Assessing the barriers to image-guided drug delivery

(2013) Gregory M. Lanza et al.   Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology

Microbubble-mediated ultrasound therapy: a review of its potential in cancer treatment

(2013) Stuart Ibsen et al.   Drug Design Development and Therapy

A Thermoresponsive Bubble-Generating Liposomal System for Triggering Localized Extracellular Drug Delivery

(2012) Ko-Jie Chen et al.   ACS Nano

Gold Nanorods for Ovarian Cancer Detection with Photoacoustic Imaging and Resection Guidance via Raman Imaging in Living Mice

(2012) Jesse V. Jokerst et al.   ACS Nano

Microbubbles as Ultrasound Contrast Agents for Molecular Imaging: Preparation and Application

(2012) Sunil Unnikrishnan et al.   AMERICAN JOURNAL OF ROENTGENOLOGY

Combined Analysis of Phase III Trials Evaluating [99mTc]Tilmanocept and Vital Blue Dye for Identification of Sentinel Lymph Nodes in Clinically Node-Negative Cutaneous Melanoma

(2012) Vernon K. Sondak et al.   ANNALS OF SURGICAL ONCOLOGY

Design of ultrasonically-activatable nanoparticles using low boiling point perfluorocarbons

(2012) Paul S. Sheeran et al.   BIOMATERIALS

Effective Photothermal Chemotherapy Using Doxorubicin-Loaded Gold Nanospheres That Target EphB4 Receptors in Tumors

(2012) J. You et al.   CANCER RESEARCH

Imaging: Strategies, Controversies, and Opportunities

(2012) R. Blasberg et al.   CLINICAL CANCER RESEARCH

Dual-isotope111In/177Lu SPECT imaging as a tool in molecular imaging tracer design

(2012) Nicole M Hijnen et al.   Contrast Media & Molecular Imaging

Phase-Change Contrast Agents for Imaging and Therapy

(2012) Paul S. Sheeran et al.   CURRENT PHARMACEUTICAL DESIGN

Ultrasound Microbubbles for Molecular Diagnosis, Therapy, and Theranostics

(2012) F. Kiessling et al.   JOURNAL OF NUCLEAR MEDICINE

A brain tumor molecular imaging strategy using a new triple-modality MRI-photoacoustic-Raman nanoparticle

(2012) Moritz F Kircher et al.   NATURE MEDICINE

Multifunctional Nanoparticles: Cost Versus Benefit of Adding Targeting and Imaging Capabilities

(2012) Z. Cheng et al.   SCIENCE

Multifunctional Nanoparticles for Dual Imaging

(2011) Z. Ali et al.   ANALYTICAL CHEMISTRY

Multimeric System of99mTc-Labeled Gold Nanoparticles Conjugated to c[RGDfK(C)] for Molecular Imaging of Tumor α(v)β(3) Expression

(2011) Enrique Morales-Avila et al.   BIOCONJUGATE CHEMISTRY

cRGD-functionalized, DOX-conjugated, and 64Cu-labeled superparamagnetic iron oxide nanoparticles for targeted anticancer drug delivery and PET/MR imaging

(2011) Xiaoqiang Yang et al.   BIOMATERIALS

Nano in Cancer: Linking Chemistry, Biology, and Clinical Applications In Vivo

(2011) R. S. Dothager et al.   CANCER RESEARCH

Effects of Photoacoustic Imaging and Photothermal Ablation Therapy Mediated by Targeted Hollow Gold Nanospheres in an Orthotopic Mouse Xenograft Model of Glioma

(2011) W. Lu et al.   CANCER RESEARCH

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Essence of affinity and specificity of peanut agglutinin-immobilized fluorescent nanospheres with surface poly(N-vinylacetamide) chains for colorectal cancer

(2011) Shinji Sakuma et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Development of MRI/NIRF ‘activatable’ multimodal imaging probe based on iron oxide nanoparticles

(2011) Eui-Joon Cha et al.   JOURNAL OF CONTROLLED RELEASE

Photothermal-chemotherapy with doxorubicin-loaded hollow gold nanospheres: A platform for near-infrared light-trigged drug release

(2011) Jian You et al.   JOURNAL OF CONTROLLED RELEASE

Annexin A5-Conjugated Polymeric Micelles for Dual SPECT and Optical Detection of Apoptosis

(2011) R. Zhang et al.   JOURNAL OF NUCLEAR MEDICINE

Large-Scale Synthesis of Uniform and Extremely Small-Sized Iron Oxide Nanoparticles for High-ResolutionT1Magnetic Resonance Imaging Contrast Agents

(2011) Byung Hyo Kim et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Iron oxide nanoparticles for targeted cancer imaging and diagnostics

(2011) Joshua E. Rosen et al.   Nanomedicine-Nanotechnology Biology and Medicine

Nanoparticles that communicate in vivo to amplify tumour targeting

(2011) Geoffrey von Maltzahn et al.   NATURE MATERIALS

Tumor Angiogenic Marker Expression Levels during Tumor Growth: Longitudinal Assessment with Molecularly Targeted Microbubbles and US Imaging

(2011) Nirupama Deshpande et al.   RADIOLOGY

Targeted imaging of tumor-associated M2 macrophages using a macromolecular contrast agent PG-Gd-NIR813

(2010) Marites P. Melancon et al.   BIOMATERIALS

Molecular imaging: current status and emerging strategies

(2010) M.A. Pysz et al.   CLINICAL RADIOLOGY

Diagnostic performance of USPIO-enhanced MRI for lymph-node metastases in different body regions: A meta-analysis

(2010) Liucheng Wu et al.   EUROPEAN JOURNAL OF RADIOLOGY

Mathematical spatio-temporal model of drug delivery from low temperature sensitive liposomes during radiofrequency tumour ablation

(2010) Astrid Gasselhuber et al.   INTERNATIONAL JOURNAL OF HYPERTHERMIA

BR55: A Lipopeptide-Based VEGFR2-Targeted Ultrasound Contrast Agent for Molecular Imaging of Angiogenesis

(2010) Sibylle Pochon et al.   INVESTIGATIVE RADIOLOGY

Theranostics With Multifunctional Magnetic Gold Nanoshells

(2010) Marites P. Melancon et al.   INVESTIGATIVE RADIOLOGY

The Path to Personalized Medicine

(2010) Margaret A. Hamburg et al.   NEW ENGLAND JOURNAL OF MEDICINE

Activatable cell penetrating peptides linked to nanoparticles as dual probes for in vivo fluorescence and MR imaging of proteases

(2010) E. S. Olson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Temperature-Sensitive Liposomal1H CEST and19F Contrast Agent for MR Image-Guided Drug Delivery

(2009) Sander Langereis et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

MR thermometry

(2008) Viola Rieke et al.   JOURNAL OF MAGNETIC RESONANCE IMAGING