Article
Biochemistry & Molecular Biology
Teodora-Irina Adam-Bonci, Eduard-Alexandru Bonci, Alina-Elena Parvu, Andrei-Ioan Herdean, Augustin Mot, Marian Taulescu, Andrei Ungur, Raluca-Maria Pop, Corina Bocsan, Alexandru Irimie
Summary: The study showed that oral vitamin D supplementation can reduce oxidative forces and increase antioxidant capacity, while also exhibiting anti-inflammatory effects to protect against acute airway inflammation related to oxidative stress processes induced by ovalbumin.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Pharmacology & Pharmacy
Elham Moslemi, Vali Musazadeh, Zeynab Kavyani, Navid Naghsh, Seyyed Morteza Seyyed Shoura, Parvin Dehghan
Summary: This umbrella meta-analysis summarized existing systematic reviews and meta-analyses of clinical trials on vitamin D supplementation. The findings revealed that vitamin D supplementation significantly reduced serum levels of CRP, TNF-alpha, and MDA, but did not show significant changes in IL-6, TAC, and GSH. Vitamin D could be considered as an adjuvant therapy for relieving inflammation and oxidative stress.
PHARMACOLOGICAL RESEARCH
(2022)
Article
Pharmacology & Pharmacy
Samia Omar, Radwa Maher El Borolossy, Tamer Elsaid, Nagwa A. Sabri
Summary: The combination of rutin and vitamin C has shown significant improvement in oxidative stress and inflammation in hemodialysis patients, reducing symptoms and risks.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Immunology
Ebin Johny, Aishwarya Jala, Bishamber Nath, Md Jahangir Alam, Indra Kuladhipati, Rupam Das, Roshan M. Borkar, Ramu Adela
Summary: Vitamin D supplementation may help reduce or prevent disease progression and cardiovascular risk in type 2 diabetes patients by suppressing oxidative stress and platelet-mediated inflammation.
FRONTIERS IN IMMUNOLOGY
(2022)
Review
Biochemistry & Molecular Biology
Thi Thuy Uyen Nguyen, Ji-hyun Yeom, Won Kim
Summary: Vitamin E supplementation significantly decreased inflammation and oxidative stress biomarkers in adult patients receiving hemodialysis, suggesting that it may help alleviate endothelial dysfunction.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Review
Biochemistry & Molecular Biology
Sujit Kumar Bhutia
Summary: Vitamin D regulates cellular homeostasis through activating autophagy, protecting against oxidative stress and apoptosis, and inducing anticancer mechanisms. It also modulates inflammation and host immunity through autophagy signaling.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY
(2022)
Review
Nutrition & Dietetics
Dongli Xie, Jianchen Hu, Zhenhua Yang, Tong Wu, Wei Xu, Qingyang Meng, Kangli Cao, Xiaogang Luo
Summary: Supplementation of vitamin E can effectively reduce oxidative stress and inflammatory responses induced by nanomaterials, providing a cost-effective option for prevention.
Review
Obstetrics & Gynecology
Soudabe Motamed, Bahareh Nikooyeh, Razieh Anari, Somayeh Motamed, Zeinab Mokhtari, Tirang Neyestani
Summary: Vitamin D supplementation significantly increased the levels of 25(OH)D, TAC and GSH in pregnant women, while significantly decreasing the levels of MDA. However, it had no significant impact on hs-CRP concentrations.
BMC PREGNANCY AND CHILDBIRTH
(2022)
Article
Medicine, Research & Experimental
Hongri Wang, Xuzheng Chen, Xueqin Miao, Kunbin Lu, Mengjuan He, Xiaomei Wu
Summary: Dendrobium mixture (DMix) improved gestational diabetes mellitus (GDM) by inhibiting oxidative condition, inflammation factors, hyperglycemia, and hyperlipidemia. This research provides a new approach for the prevention and treatment of GDM.
BIOMEDICINE & PHARMACOTHERAPY
(2022)
Review
Biochemistry & Molecular Biology
Izabela Szymczak-Pajor, Krystian Miazek, Anna Selmi, Aneta Balcerczyk, Agnieszka Sliwinska
Summary: Adipose tissue plays a crucial role in metabolism, while deficiency in vitamin D can disrupt its functioning. Restoring the proper functionality of adipose tissue is important in reducing the risk of obesity-related complications.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Review
Food Science & Technology
Vivek Rihal, Heena Khan, Amarjot Kaur, Thakur Gurjeet Singh
Summary: Vitamin D deficiency is associated with chronic diseases such as cardiovascular and neurodegenerative diseases, diabetes, and cancer. Therapeutic approaches targeting vitamin D inadequacies and its downstream effects may delay the onset and severity of cerebrovascular disorders such as stroke and neurologic malformations.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Article
Biochemistry & Molecular Biology
Liyun Wu, Wenjie Xu, Hongyan Li, Bo Dong, Hancheng Geng, Junyan Jin, Dong Han, Haokun Liu, Xiaoming Zhu, Yunxia Yang, Shouqi Xie
Summary: Previous studies have shown that vitamin C has a protective effect in fish. In this study, it was found that vitamin C can attenuate oxidative damage, inflammation, and acute hypoxia-induced apoptosis in gibel carp. This protective mechanism is mediated through the activation of the Nrf2/Keap1 signaling pathway. These findings provide new insights into the defense strategies of fish under hypoxic conditions.
Article
Biochemistry & Molecular Biology
Huaxin Li, Mengxue Zhang, Yuanyu Wang, Ke Gong, Tengteng Yan, Dandan Wang, Xianshe Meng, Xiaoxiao Yang, Yuanli Chen, Jihong Han, Yajun Duan, Shuang Zhang
Summary: This study demonstrates that Daidzein (DAI) can alleviate heart failure (HF) by regulating cardiac energy metabolism, improving cardiac function, reducing inflammation, oxidative stress, apoptosis, and fibrosis.
Article
Nutrition & Dietetics
Myunghee Kim, Hyeyoon Eo, Josephine Gahyun Lim, Hyunjung Lim, Yunsook Lim
Summary: This meta-analysis found that dietary vitamin E supplementation can attenuate exercise-induced muscle damage, especially when the supplementation is less than 500 IU.
Review
Cell Biology
Nyshadham S. N. Chaitanya, Prasad Tammineni, Ganji Purnachandra Nagaraju, Aramati B. M. Reddy
Summary: The cytosolic adaptor protein ECSIT is involved in the toll-like receptor pathway and regulates various biological processes. It interacts with multiple signaling intermediates and its molecular functions in pathophysiology remain unclear.
JOURNAL OF CELLULAR PHYSIOLOGY
(2022)