Review
Nutrition & Dietetics
Dongli Xie, Jianchen Hu, Zhenhua Yang, Tong Wu, Wei Xu, Qingyang Meng, Kangli Cao, Xiaogang Luo
Summary: Supplementation of vitamin E can effectively reduce oxidative stress and inflammatory responses induced by nanomaterials, providing a cost-effective option for prevention.
Review
Obstetrics & Gynecology
Soudabe Motamed, Bahareh Nikooyeh, Razieh Anari, Somayeh Motamed, Zeinab Mokhtari, Tirang Neyestani
Summary: Vitamin D supplementation significantly increased the levels of 25(OH)D, TAC and GSH in pregnant women, while significantly decreasing the levels of MDA. However, it had no significant impact on hs-CRP concentrations.
BMC PREGNANCY AND CHILDBIRTH
(2022)
Article
Biochemistry & Molecular Biology
Teodora-Irina Adam-Bonci, Eduard-Alexandru Bonci, Alina-Elena Parvu, Andrei-Ioan Herdean, Augustin Mot, Marian Taulescu, Andrei Ungur, Raluca-Maria Pop, Corina Bocsan, Alexandru Irimie
Summary: The study showed that oral vitamin D supplementation can reduce oxidative forces and increase antioxidant capacity, while also exhibiting anti-inflammatory effects to protect against acute airway inflammation related to oxidative stress processes induced by ovalbumin.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Nutrition & Dietetics
Myunghee Kim, Hyeyoon Eo, Josephine Gahyun Lim, Hyunjung Lim, Yunsook Lim
Summary: This meta-analysis found that dietary vitamin E supplementation can attenuate exercise-induced muscle damage, especially when the supplementation is less than 500 IU.
Review
Biochemistry & Molecular Biology
Izabela Szymczak-Pajor, Krystian Miazek, Anna Selmi, Aneta Balcerczyk, Agnieszka Sliwinska
Summary: Adipose tissue plays a crucial role in metabolism, while deficiency in vitamin D can disrupt its functioning. Restoring the proper functionality of adipose tissue is important in reducing the risk of obesity-related complications.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Review
Food Science & Technology
Vivek Rihal, Heena Khan, Amarjot Kaur, Thakur Gurjeet Singh
Summary: Vitamin D deficiency is associated with chronic diseases such as cardiovascular and neurodegenerative diseases, diabetes, and cancer. Therapeutic approaches targeting vitamin D inadequacies and its downstream effects may delay the onset and severity of cerebrovascular disorders such as stroke and neurologic malformations.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Review
Biochemistry & Molecular Biology
Thi Thuy Uyen Nguyen, Ji-hyun Yeom, Won Kim
Summary: Vitamin E supplementation significantly decreased inflammation and oxidative stress biomarkers in adult patients receiving hemodialysis, suggesting that it may help alleviate endothelial dysfunction.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Biochemistry & Molecular Biology
Francesco Violi, Cristina Nocella, Lorenzo Loffredo, Roberto Carnevale, Pasquale Pignatelli
Summary: Vitamin E possesses antioxidant and anti-inflammatory properties that have an impact on atherosclerosis and thrombus formation, but intervention trials have yielded negative results.
FREE RADICAL BIOLOGY AND MEDICINE
(2022)
Review
Biochemistry & Molecular Biology
Sujit Kumar Bhutia
Summary: Vitamin D regulates cellular homeostasis through activating autophagy, protecting against oxidative stress and apoptosis, and inducing anticancer mechanisms. It also modulates inflammation and host immunity through autophagy signaling.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY
(2022)
Article
Immunology
Ebin Johny, Aishwarya Jala, Bishamber Nath, Md Jahangir Alam, Indra Kuladhipati, Rupam Das, Roshan M. Borkar, Ramu Adela
Summary: Vitamin D supplementation may help reduce or prevent disease progression and cardiovascular risk in type 2 diabetes patients by suppressing oxidative stress and platelet-mediated inflammation.
FRONTIERS IN IMMUNOLOGY
(2022)
Review
Immunology
Arduino A. Mangoni, Angelo Zinellu
Summary: This study evaluated the pathophysiological role of neopterin in patients with rheumatic diseases through systematic review and meta-analysis. The results showed that neopterin concentrations were significantly higher in patients with RD compared to healthy controls. However, there were no significant associations found between neopterin concentrations and factors such as age and gender ratio, but associations were observed with geographical area and type of RD.
FRONTIERS IN IMMUNOLOGY
(2023)
Article
Nutrition & Dietetics
Maria Hernandez, Sergio Recalde, Jorge Gonzalez-Zamora, Valentina Bilbao-Malave, Manuel Saenz de Viteri, Jaione Bezunartea, Maite Moreno-Orduna, Idoia Belza, Jesus Barrio-Barrio, Patricia Fernandez-Robredo, Alfredo Garcia-Layana
Summary: Combining vitamin D with Nutrof Total(R) provides synergistic protection against oxidative and inflammatory stress-induced conditions in retinal epithelial and endothelial cells, reducing cell damage and inflammation.
Article
Immunology
Ya-Qi Wang, Xiao-Pan Geng, Ming-Wei Wang, Hong-Qian Wang, Cheng Zhang, Xue He, Shi-Min Liang, De-Xiang Xu, Xi Chen
Summary: Experimental data suggests that VDD exacerbates hepatic oxidative stress and inflammation during APAP-induced ALI.
INTERNATIONAL IMMUNOPHARMACOLOGY
(2021)
Review
Medicine, General & Internal
Elisabetta Zinellu, Alessandro G. Fois, Elisabetta Sotgiu, Sabrina Mellino, Arduino A. Mangoni, Ciriaco Carru, Angelo Zinellu, Pietro Pirina
Summary: This systematic review and meta-analysis revealed that serum albumin concentrations are significantly lower in patients with stable COPD compared to non-COPD controls, indicating a deficiency in systemic anti-inflammatory and antioxidant defense mechanisms in COPD.
JOURNAL OF CLINICAL MEDICINE
(2021)
Review
Biochemistry & Molecular Biology
Alice Albergamo, Giulia Apprato, Francesca Silvagno
Summary: The genomic activity of vitamin D has significant effects on metabolism and physiological functions, particularly in relation to viral infections such as COVID-19. This review examines the correlation between vitamin D deficiency and increased risks of severe COVID-19 and respiratory distress syndrome. Clinical trials have tested vitamin D supplementation with promising results. Additionally, a biochemical analysis explores the antioxidant and anti-inflammatory functions of vitamin D and its influence on different biochemical pathways in the body's defense against viral infections.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Review
Food Science & Technology
Vali Musazadeh, Meysam Zarezadeh, Amir Hossein Faghfouri, Majid Keramati, Parmida Jamilian, Parsa Jamilian, Arash Mohagheghi, Alireza Farnam
Summary: A meta-analysis was conducted to investigate the impact of probiotic supplementation on depressive symptoms. The results showed that consuming probiotics can significantly reduce depression symptoms, especially with intervention duration >8 weeks and dosage >10 x 10(9) CFU.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Review
Cardiac & Cardiovascular Systems
Meysam Zarezadeh, Vali Musazadeh, Faezeh Ghalichi, Zeynab Kavyani, Romina Nasernia, Maryam Parang, Parmida Jamilian, Parsa Jamilian, Laleh Fakhr, Alireza Ostadrahimi, Rania A. Mekary
Summary: An umbrella meta-analysis suggests that probiotics supplementation can significantly lower blood pressure and may be used as a complementary therapy for controlling high blood pressure. Trials with a mean age of >50 years and interventions lasting ≤10 weeks show greater effects on systolic blood pressure. Studies with a dosage of ≥1010 colony forming unit (CFU) demonstrate a reduction in diastolic blood pressure, and patients with hypertension or diabetes show a decrease in systolic blood pressure.
NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES
(2023)
Review
Biochemistry & Molecular Biology
Mahdi Vajdi, Vali Musazadeh, Arash Karimi, Hajar Heidari, Mohammad Javad Tarrahi, Gholamreza Askari
Summary: This study summarized meta-analyses on the effects of chromium supplementation on lipid profiles in adults. The results showed that chromium supplementation did not have a significant effect on blood lipid levels and cannot be used as a single therapy for treating lipid abnormalities in adults.
BIOLOGICAL TRACE ELEMENT RESEARCH
(2023)
Review
Pharmacology & Pharmacy
Vali Musazadeh, Arash Karimi, Mahsa Malekahmadi, Sana Sedgh Ahrabi, Parvin Dehghan
Summary: In this umbrella meta-analysis, the effect of omega-3 polyunsaturated fatty acid (PUFA) supplementation on non-alcoholic fatty liver disease (NAFLD) was evaluated. The analysis showed that PUFA supplementation had beneficial effects on liver function tests (AST, ALT, and GGT) and liver fat in patients with NAFLD. Therefore, omega-3 PUFAs could be considered as a therapeutic option in the treatment of NAFLD.
CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY
(2023)
Letter
Pharmacology & Pharmacy
Elham Moslemi, Vali Musazadeh, Zeynab Kavyani, Navid Naghsh, Seyyed Morteza Seyyed Shoura, Parvin Dehghan
PHARMACOLOGICAL RESEARCH
(2023)
Article
Multidisciplinary Sciences
Aydin Aynehchi, Sevda Saleh-Ghadimi, Parvin Dehghan
Summary: Globally, around three billion people are either under- or overweight. This study examined the impact of self-efficacy and coping strategies on eating behaviors, dietary intake and BMI, and found that improving self-efficacy and coping-strategies is helpful to maintain a healthy BMI in both BMI groups.
Article
Medicine, Research & Experimental
Saba Saati, Parvin Dehghan, Fatemeh Azizi-Soleiman, Majid Mobasseri
Summary: This study aims to investigate the effects of bitter almond gum supplementation on metabolic profile, inflammatory markers, and mental health in women with type 2 diabetes mellitus. A randomized, triple-blind, placebo-controlled trial will be conducted with 44 women. Clinical and biochemical outcome parameters will be measured at baseline and the end of the study. Statistical analysis will be performed using SPSS software.
Review
Endocrinology & Metabolism
Vali Musazadeh, Zeynab Kavyani, Naghmeh Mirhosseini, Parvin Dehghan, Mahdi Vajdi
Summary: Vitamin D supplementation has a supportive effect on improving glycemic status, but the results are inconclusive. This umbrella meta-analysis examined the impact of vitamin D on type 2 diabetes biomarkers and included 37 meta-analyses. The findings indicated that vitamin D supplementation significantly decreased fasting blood sugar, hemoglobin A1c, insulin concentrations, and homeostatic model assessment for insulin resistance.
DIABETOLOGY & METABOLIC SYNDROME
(2023)
Article
Medicine, General & Internal
Mehdi Mohammadi Zadeh, Parvin Dehghan, Zahra Eslami
Summary: This study aims to evaluate the effectiveness of date seed powder (DSP) as a functional food (prebiotic) on various health parameters in patients with type 2 diabetes mellitus (T2DM). A randomized, triple-blind, placebo-controlled trial will be conducted, with 48 T2DM patients assigned to receive either DSP or placebo for 8 weeks. Blood samples will be collected to assess several health markers. The study hopes to contribute to scientific knowledge on the effects of DSP supplementation in T2DM patients.
Article
Nutrition & Dietetics
Zeynab Kavyani, Parvin Dehghan, Mostafa Khani, Mousa Khalafi, Sara K. Rosenkranz
Summary: The study aimed to evaluate the independent and combined effects of camelina sativa oil and high-intensity interval training (HIIT) on liver function and metabolic outcomes in streptozotocin-induced diabetic rats. The results showed that the combination of camelina sativa oil and HIIT had greater effects on reducing liver inflammation and improving metabolic outcomes compared to camelina sativa oil or HIIT alone. This suggests that the combination of camelina sativa oil and HIIT could be a beneficial intervention for diabetes management.
FRONTIERS IN NUTRITION
(2023)
Review
Nutrition & Dietetics
Vali Musazadeh, Maryam Mohammadi Anilou, Mahdi Vajdi, Arash Karimi, Sana Sedgh Ahrabi, Parvin Dehghan
Summary: This umbrella meta-analysis found that synbiotic supplementation can slightly improve lipid profiles and anthropometric parameters, suggesting it may be a therapeutic option for obesity and its related disorders.
FRONTIERS IN NUTRITION
(2023)
Review
Pharmacology & Pharmacy
Sara Dabbaghi Varnousfaderani, Vali Musazadeh, Faezeh Ghalichi, Zeynab Kavyani, Soha Razmjouei, Amir Hossein Faghfouri, Sana Sedgh Ahrabi, Seyyed Morteza Seyyed Shoura, Parvin Dehghan
Summary: Through a comprehensive meta-analysis, it was found that CoQ10 has a positive effect on oxidative stress and inflammation markers. However, some studies have shown contradictory results. CoQ10 supplementation significantly reduced serum CRP and MDA levels, while increasing TAC and SOD activity. However, it did not have a significant reducing effect on TNF-α and IL-6 levels.
FRONTIERS IN PHARMACOLOGY
(2023)
Review
Immunology
Amir Hossein Faghfouri, Ladan Gol Mohammad Pour Afrakoti, Zeynab Kavyani, Zahra Sadeghi Nogourani, Vali Musazadeh, Mahdi Jafarlou, Parvin Dehghan
Summary: This umbrella meta-analysis found that probiotic supplementation significantly reduced serum concentrations of C-reactive protein, TNF-alpha, and interleukin-6. Therefore, probiotic supplementation can be considered as an adjuvant therapy to alleviate inflammation in various inflammatory conditions.
INFLAMMOPHARMACOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Vali Musazadeh, Ahmad Nazari, Amir Hossein Faghfouri, Mohammad Emami, Zeynab Kavyani, Maryam Zokaei, Parmida Jamilian, Meysam Zarezadeh, Ahmad Saedisomeolia
Summary: This umbrella meta-analysis aimed to summarize the effects of probiotic supplementation on Helicobacter pylori (H. pylori) eradication. The findings indicated that probiotics have a beneficial impact on H. pylori eradication, especially when administered in higher doses (>10 x 10(10) CFU) and with mixed strains.
Review
Nutrition & Dietetics
Vali Musazadeh, Shaghayegh Abbasi, Zeynab Kavyani, Amir Hossein Moridpour, Diba Safarzadeh, Zahra Moradi, Fatemeh Bahadori, Amir Hossein Faghfouri
Summary: This study found that curcumin supplementation can increase serum adiponectin and decrease leptin levels.
BRITISH JOURNAL OF NUTRITION
(2023)