Novel loci for childhood body mass index and shared heritability with adult cardiometabolic traits

Low-frequency variation in TP53 has large effects on head circumference and intracranial volume

(2019) Simon Haworth et al.   Nature Communications

Polygenic Prediction of Weight and Obesity Trajectories from Birth to Adulthood

(2019) Amit V. Khera et al.   CELL

Genome-wide association study reveals dynamic role of genetic variation in infant and early childhood growth

(2019) Øyvind Helgeland et al.   Nature Communications

Body mass index, sitting time, and risk of Parkinson disease

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Change in Overweight from Childhood to Early Adulthood and Risk of Type 2 Diabetes

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Ablation of PM20D1 revealsN-acyl amino acid control of metabolism and nociception

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Influence of FTO rs9939609 polymorphism on appetite, ghrelin, leptin, IL6, TNFα levels, and food intake of women with morbid obesity

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The UK Biobank resource with deep phenotyping and genomic data

(2018) Clare Bycroft et al.   NATURE

The Rotterdam Study: 2018 update on objectives, design and main results

(2017) M. Arfan Ikram et al.   EUROPEAN JOURNAL OF EPIDEMIOLOGY

Worldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016: a pooled analysis of 2416 population-based measurement studies in 128·9 million children, adolescents, and adults

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Childhood body mass index and development of type 2 diabetes throughout adult life-A large-scale danish cohort study

(2017) Esther Zimmermann et al.   Obesity

Genetic and environmental effects on body mass index from infancy to the onset of adulthood: an individual-based pooled analysis of 45 twin cohorts participating in the COllaborative project of Development of Anthropometrical measures in Twins (CODATwins) study

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PhenoScanner: a database of human genotype–phenotype associations

(2016) James R. Staley et al.   BIOINFORMATICS

The Secreted Enzyme PM20D1 Regulates Lipidated Amino Acid Uncouplers of Mitochondria

(2016) Jonathan Z. Long et al.   CELL

Temporal Relationship Between Childhood Body Mass Index and Insulin and Its Impact on Adult HypertensionNovelty and Significance

(2016) Tao Zhang et al.   HYPERTENSION

Identification of a Novel Autoimmune Peptide Epitope of Prostein in Prostate Cancer

(2016) Elisa Pin et al.   JOURNAL OF PROTEOME RESEARCH

High-throughput discovery of novel developmental phenotypes

(2016) Mary E. Dickinson et al.   NATURE

Detection and interpretation of shared genetic influences on 42 human traits

(2016) Joseph K Pickrell et al.   NATURE GENETICS

New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk

(2016) Yingchang Lu et al.   Nature Communications

Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

(2016) Thomas W. Winkler et al.   PLoS Genetics

Nedd4-2 haploinsufficiency causes hyperactivity and increased sensitivity to inflammatory stimuli

(2016) Sudhirkumar Yanpallewar et al.   Scientific Reports

Genetic variants at 1q32.1, 10q11.2 and 19q13.41 are associated with prostate-specific antigen for prostate cancer screening in two Korean population-based cohort studies

(2015) Soriul Kim et al.   GENE

NEDD4-2 (NEDD4L): The ubiquitin ligase for multiple membrane proteins

(2015) Pranay Goel et al.   GENE

Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index

(2015) Janine F. Felix et al.   HUMAN MOLECULAR GENETICS

Genetic studies of body mass index yield new insights for obesity biology

(2015) Adam E. Locke et al.   NATURE

Genetic variance estimation with imputed variants finds negligible missing heritability for human height and body mass index

(2015) Jian Yang et al.   NATURE GENETICS

An atlas of genetic correlations across human diseases and traits

(2015) Brendan Bulik-Sullivan et al.   NATURE GENETICS

LD Score regression distinguishes confounding from polygenicity in genome-wide association studies

(2015) Brendan K Bulik-Sullivan et al.   NATURE GENETICS

Stable intergenerational associations of childhood overweight during the development of the obesity epidemic

(2015) Teresa A. Ajslev et al.   Obesity

The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans

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UK Biobank: An Open Access Resource for Identifying the Causes of a Wide Range of Complex Diseases of Middle and Old Age

(2015) Cathie Sudlow et al.   PLOS MEDICINE

Body Mass Index and Risk of Parkinson’s Disease: A Dose-Response Meta-Analysis of Prospective Studies

(2015) Yun-Liang Wang et al.   PLoS One

Evidence of Early Alterations in Adipose Tissue Biology and Function and Its Association With Obesity-Related Inflammation and Insulin Resistance in Children

(2014) Kathrin Landgraf et al.   DIABETES

Mendelian randomization: genetic anchors for causal inference in epidemiological studies

(2014) G. Davey Smith et al.   HUMAN MOLECULAR GENETICS

A general framework for estimating the relative pathogenicity of human genetic variants

(2014) Martin Kircher et al.   NATURE GENETICS

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Trends in Parent-Child Correlations of Childhood Body Mass Index during the Development of the Obesity Epidemic

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Bayesian Test for Colocalisation between Pairs of Genetic Association Studies Using Summary Statistics

(2014) Claudia Giambartolomei et al.   PLoS Genetics

Satiety Mechanisms in Genetic Risk of Obesity

(2014) Clare H. Llewellyn et al.   JAMA Pediatrics

Genome-wide analysis of BMI in adolescents and young adults reveals additional insight into the effects of genetic loci over the life course

(2013) Mariaelisa Graff et al.   HUMAN MOLECULAR GENETICS

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

(2013) Sonja I Berndt et al.   NATURE GENETICS

Matrix eQTL: ultra fast eQTL analysis via large matrix operations

(2012) A. A. Shabalin   BIOINFORMATICS

Genome-wide association study identified novel genetic variant on SLC45A3 gene associated with serum levels prostate-specific antigen (PSA) in a Chinese population

(2012) Jielin Sun et al.   HUMAN GENETICS

Nedd4 and Nedd4-2: Ubiquitin ligases at work in the neuron

(2012) Prudence Donovan et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Is Obesity at Individual and National Level Associated With Lower Age at Menarche? Evidence From 34 Countries in the Health Behaviour in School-aged Children Study

(2012) Candace Currie et al.   JOURNAL OF ADOLESCENT HEALTH

Conditional and joint multiple-SNP analysis of GWAS summary statistics identifies additional variants influencing complex traits

(2012) Jian Yang et al.   NATURE GENETICS

Genome partitioning of genetic variation for complex traits using common SNPs

(2011) Jian Yang et al.   NATURE GENETICS

Adolescent BMI Trajectory and Risk of Diabetes versus Coronary Disease

(2011) Amir Tirosh et al.   NEW ENGLAND JOURNAL OF MEDICINE

Childhood Adiposity, Adult Adiposity, and Cardiovascular Risk Factors

(2011) Markus Juonala et al.   NEW ENGLAND JOURNAL OF MEDICINE

Increased Genetic Variance of BMI with a Higher Prevalence of Obesity

(2011) Benjamin Rokholm et al.   PLoS One

Increasing Genetic Variance of Body Mass Index during the Swedish Obesity Epidemic

(2011) Benjamin Rokholm et al.   PLoS One

Association between Common Variation at the FTO Locus and Changes in Body Mass Index from Infancy to Late Childhood: The Complex Nature of Genetic Association through Growth and Development

(2011) Ulla Sovio et al.   PLoS Genetics

METAL: fast and efficient meta-analysis of genomewide association scans

(2010) C. J. Willer et al.   BIOINFORMATICS

Comparison of normalization methods for Illumina BeadChip HumanHT-12 v3

(2010) Ramona Schmid et al.   BMC GENOMICS

A re-annotation pipeline for Illumina BeadArrays: improving the interpretation of gene expression data

(2009) Nuno L. Barbosa-Morais et al.   NUCLEIC ACIDS RESEARCH

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(2008) P. Du et al.   BIOINFORMATICS

Obesity Associated Genetic Variation inFTOIs Associated with Diminished Satiety

(2008) Jane Wardle et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

(2008) Da Wei Huang et al.   NUCLEIC ACIDS RESEARCH

Tracking of childhood overweight into adulthood: a systematic review of the literature

(2008) A. S. Singh et al.   Obesity Reviews