Genome-wide association study reveals dynamic role of genetic variation in infant and early childhood growth

Subcellular localization of MC4R with ADCY3 at neuronal primary cilia underlies a common pathway for genetic predisposition to obesity

(2018) Jacqueline E. Siljee et al.   NATURE GENETICS

Loss-of-function variants in ADCY3 increase risk of obesity and type 2 diabetes

(2018) Niels Grarup et al.   NATURE GENETICS

Loss-of-function mutations in ADCY3 cause monogenic severe obesity

(2018) Sadia Saeed et al.   NATURE GENETICS

Heritability enrichment of specifically expressed genes identifies disease-relevant tissues and cell types

(2018) Hilary K. Finucane et al.   NATURE GENETICS

Meta-analysis of genome-wide association studies for height and body mass index in ∼700000 individuals of European ancestry

(2018) Loic Yengo et al.   HUMAN MOLECULAR GENETICS

Acceleration of BMI in Early Childhood and Risk of Sustained Obesity

(2018) Mandy Geserick et al.   NEW ENGLAND JOURNAL OF MEDICINE

Genetic effects on gene expression across human tissues

(2017) François Aguet et al.   NATURE

Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk

(2017) Felix R Day et al.   NATURE GENETICS

Connecting genetic risk to disease end points through the human blood plasma proteome

(2017) Karsten Suhre et al.   Nature Communications

Genetic and environmental effects on body mass index from infancy to the onset of adulthood: an individual-based pooled analysis of 45 twin cohorts participating in the COllaborative project of Development of Anthropometrical measures in Twins (CODATwins) study

(2016) Karri Silventoinen et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease

(2016) William J. Astle et al.   CELL

Cohort Profile Update: The Norwegian Mother and Child Cohort Study (MoBa)

(2016) Per Magnus et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Genome-wide associations for birth weight and correlations with adult disease

(2016) Momoko Horikoshi et al.   NATURE

Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels

(2016) Tuomas O. Kilpeläinen et al.   Nature Communications

The soluble leptin receptor

(2015) Michael Schaab et al.   BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM

Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index

(2015) Janine F. Felix et al.   HUMAN MOLECULAR GENETICS

A genome-wide association study of body mass index across early life and childhood

(2015) N. M. Warrington et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Leptin resistance and diet-induced obesity: central and peripheral actions of leptin

(2015) Neira Sáinz et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Genetic studies of body mass index yield new insights for obesity biology

(2015) Adam E. Locke et al.   NATURE

LD Score regression distinguishes confounding from polygenicity in genome-wide association studies

(2015) Brendan K Bulik-Sullivan et al.   NATURE GENETICS

Shared genetic aetiology of puberty timing between sexes and with health-related outcomes

(2015) Felix R. Day et al.   Nature Communications

Efficient haplotype matching and storage using the positional Burrows-Wheeler transform (PBWT)

(2014) R. Durbin   BIOINFORMATICS

Multiethnic Meta-Analysis of Genome-Wide Association Studies in >100 000 Subjects Identifies 23 Fibrinogen-Associated Loci but No Strong Evidence of a Causal Association Between Circulating Fibrinogen and Cardiovascular Disease

(2013) Maria Sabater-Lleal et al.   CIRCULATION

Genome-wide SNP and CNV analysis identifies common and low-frequency variants associated with severe early-onset obesity

(2013) Eleanor Wheeler et al.   NATURE GENETICS

A changing pattern of childhood BMI growth during the 20th century: 70 y of data from the Fels Longitudinal Study

(2012) William Johnson et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

A genome-wide association meta-analysis identifies new childhood obesity loci

(2012)   NATURE GENETICS

Improved whole-chromosome phasing for disease and population genetic studies

(2012) Olivier Delaneau et al.   NATURE METHODS

Heritability Estimates of Body Size in Fetal Life and Early Childhood

(2012) Dennis O. Mook-Kanamori et al.   PLoS One

Association between Common Variation at the FTO Locus and Changes in Body Mass Index from Infancy to Late Childhood: The Complex Nature of Genetic Association through Growth and Development

(2011) Ulla Sovio et al.   PLoS Genetics

Genome-wide association study identifies polymorphisms in LEPR as determinants of plasma soluble leptin receptor levels

(2010) Qi Sun et al.   HUMAN MOLECULAR GENETICS

Genetic Loci Associated With C-Reactive Protein Levels and Risk of Coronary Heart Disease

(2009) Paul Elliott   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Genetic Determinants of Height Growth Assessed Longitudinally from Infancy to Adulthood in the Northern Finland Birth Cohort 1966

(2009) Ulla Sovio et al.   PLoS Genetics