Ablation of PM20D1 revealsN-acyl amino acid control of metabolism and nociception

PM20D1 is a quantitative trait locus associated with Alzheimer’s disease

(2018) Jose V. Sanchez-Mut et al.   NATURE MEDICINE

N-Oleoylglycine-Induced Hyperphagia Is Associated with the Activation of Agouti-Related Protein (AgRP) Neuron by Cannabinoid Receptor Type 1 (CB1R)

(2017) Junguo Wu et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

The Secreted Enzyme PM20D1 Regulates Lipidated Amino Acid Uncouplers of Mitochondria

(2016) Jonathan Z. Long et al.   CELL

N-Acyl amino acids and their impact on biological processes

(2014) Lumír Hanuš et al.   BIOFACTORS

Novel endogenous N-acyl amides activate TRPV1-4 receptors, BV-2 microglia, and are regulated in brain in an acute model of inflammation

(2014) Siham Raboune et al.   Frontiers in Cellular Neuroscience

TRPV1 Channels Are Intrinsically Heat Sensitive and Negatively Regulated by Phosphoinositide Lipids

(2013) Erhu Cao et al.   NEURON

Effects of the TRPV1 antagonist ABT-102 on body temperature in healthy volunteers: pharmacokinetic/ pharmacodynamic analysis of three phase 1 trials

(2012) Ahmed A. Othman et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

The Economic Costs of Pain in the United States

(2012) Darrell J. Gaskin et al.   JOURNAL OF PAIN

17(R)-resolvin D1 specifically inhibits transient receptor potential ion channel vanilloid 3 leading to peripheral antinociception

(2011) S Bang et al.   BRITISH JOURNAL OF PHARMACOLOGY

Resolvin D2 Is a Potent Endogenous Inhibitor for Transient Receptor Potential Subtype V1/A1, Inflammatory Pain, and Spinal Cord Synaptic Plasticity in Mice: Distinct Roles of Resolvin D1, D2, and E1

(2011) C.-K. Park et al.   JOURNAL OF NEUROSCIENCE

Mechanistic and Pharmacological Characterization of PF-04457845: A Highly Potent and Selective Fatty Acid Amide Hydrolase Inhibitor That Reduces Inflammatory and Noninflammatory Pain

(2011) K. Ahn et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Endocannabinoid-like N-arachidonoyl serine is a novel pro-angiogenic mediator

(2010) X Zhang et al.   BRITISH JOURNAL OF PHARMACOLOGY

A Placebo-Controlled Trial of Oral Fingolimod in Relapsing Multiple Sclerosis

(2010) Ludwig Kappos et al.   NEW ENGLAND JOURNAL OF MEDICINE

Oleoyl serine, an endogenousN-acyl amide, modulates bone remodeling and mass

(2010) Reem Smoum et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of endogenous acyl amino acids based on a targeted lipidomics approach

(2009) Bo Tan et al.   JOURNAL OF LIPID RESEARCH

N-Palmitoyl Glycine, a Novel Endogenous Lipid That Acts As a Modulator of Calcium Influx and Nitric Oxide Production in Sensory Neurons

(2008) N. Rimmerman et al.   MOLECULAR PHARMACOLOGY

Transient receptor potential channels: targeting pain at the source

(2008) Ardem Patapoutian et al.   NATURE REVIEWS DRUG DISCOVERY

Actions of N-arachidonyl-glycine in a rat neuropathic pain model

(2007) Leeza A.Q. Vuong et al.   NEUROPHARMACOLOGY