Drosophila Caliban preserves intestinal homeostasis and lifespan through regulating mitochondrial dynamics and redox state in enterocytes

MISTERMINATE Mechanistically Links Mitochondrial Dysfunction with Proteostasis Failure

(2019) Zhihao Wu et al.   MOLECULAR CELL

Mitochondrial Dysfunction in Aging and Cancer

(2019) Loredana Moro   Journal of Clinical Medicine

Mitochondrial and Reactive Oxygen Species Signaling Coordinate Stem Cell Fate Decisions and Life Long Maintenance

(2018) Mireille Khacho et al.   ANTIOXIDANTS & REDOX SIGNALING

Reactive Oxygen Species and Mitochondrial Homeostasis as Regulators of Stem Cell Fate and Function

(2018) Darren Q. Tan et al.   ANTIOXIDANTS & REDOX SIGNALING

Drosophila Caliban mediates G1-S transition and ionizing radiation induced S phase checkpoint

(2018) Fanghua Song et al.   CELL CYCLE

Dual roles of mitochondrial fusion gene FZO1 in yeast age asymmetry and in longevity mediated by a novel ATG32-dependent retrograde response

(2018) James C. Jiang et al.   BIOGERONTOLOGY

Autophagy suppresses Ras-driven epithelial tumourigenesis by limiting the accumulation of reactive oxygen species

(2017) J Manent et al.   ONCOGENE

Mitochondrial Dynamics Impacts Stem Cell Identity and Fate Decisions by Regulating a Nuclear Transcriptional Program

(2016) Mireille Khacho et al.   Cell Stem Cell

Intestinal stem cell response to injury: lessons from Drosophila

(2016) Huaqi Jiang et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Gastrointestinal stem cells in health and disease: from flies to humans

(2016) Hongjie Li et al.   Disease Models & Mechanisms

The mitochondrial outer membrane protein MDI promotes local protein synthesis and mtDNA replication

(2016) Yi Zhang et al.   EMBO JOURNAL

Mitofusin 2 maintains haematopoietic stem cells with extensive lymphoid potential

(2016) Larry L. Luchsinger et al.   NATURE

Enteroendocrine cells are generated from stem cells through a distinct progenitor in the adult Drosophila posterior midgut

(2015) X. Zeng et al.   DEVELOPMENT

Niche appropriation by Drosophila intestinal stem cell tumours

(2015) Parthive H. Patel et al.   NATURE CELL BIOLOGY

Rqc2p and 60S ribosomal subunits mediate mRNA-independent elongation of nascent chains

(2015) P. S. Shen et al.   SCIENCE

The four aldehyde oxidases of Drosophila melanogaster have different gene expression patterns and enzyme substrate specificities

(2014) Z. Marelja et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Slit/Robo Signaling Regulates Cell Fate Decisions in the Intestinal Stem Cell Lineage of Drosophila

(2014) Benoît Biteau et al.   Cell Reports

Integration of UPRER and Oxidative Stress Signaling in the Control of Intestinal Stem Cell Proliferation

(2014) Lifen Wang et al.   PLoS Genetics

Intestinal epithelium-derived BMP controls stem cell self-renewal in Drosophila adult midgut

(2014) Aiguo Tian et al.   eLife

Trachea-Derived Dpp Controls Adult Midgut Homeostasis in Drosophila

(2013) Zhouhua Li et al.   DEVELOPMENTAL CELL

Symbiotic lactobacilli stimulate gut epithelial proliferationviaNox-mediated generation of reactive oxygen species

(2013) Rheinallt M Jones et al.   EMBO JOURNAL

Mitochondrial Fusion Directs Cardiomyocyte Differentiation via Calcineurin and Notch Signaling

(2013) A. Kasahara et al.   SCIENCE

Dpp Signaling Determines Regional Stem Cell Identity in the Regenerating Adult Drosophila Gastrointestinal Tract

(2013) Hongjie Li et al.   Cell Reports

Organ-specific mediation of lifespan extension: More than a gut feeling?

(2012) Michael Rera et al.   AGEING RESEARCH REVIEWS

clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters

(2012) Guangchuang Yu et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

The tumor suppressor Caliban regulates DNA damage-induced apoptosis through p53-dependent and -independent activity

(2012) Y Wang et al.   ONCOGENE

A preliminary characterization of the cytosolic glutathione transferase proteome fromDrosophila melanogaster

(2011) Chonticha Saisawang et al.   BIOCHEMICAL JOURNAL

Drosophila EGFR pathway coordinates stem cell proliferation and gut remodeling following infection

(2011) Nicolas Buchon et al.   BMC BIOLOGY

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

(2011) P. Gaudet et al.   BRIEFINGS IN BIOINFORMATICS

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Redox Regulation by Keap1 and Nrf2 Controls Intestinal Stem Cell Proliferation in Drosophila

(2011) Christine E. Hochmuth et al.   Cell Stem Cell

EGF signaling regulates the proliferation of intestinal stem cells in Drosophila

(2011) B. Biteau et al.   DEVELOPMENT

Distinct levels of Notch activity for commitment and terminal differentiation of stem cells in the adult fly intestine

(2011) C. N. Perdigoto et al.   DEVELOPMENT

The origin of intestinal stem cells in Drosophila

(2011) Craig A. Micchelli   DEVELOPMENTAL DYNAMICS

Intestinal stem cells in the adult Drosophila midgut

(2011) Huaqi Jiang et al.   EXPERIMENTAL CELL RESEARCH

Transcriptional control of stem cell maintenance in the Drosophila intestine

(2010) A. J. Bardin et al.   DEVELOPMENT

Mitochondrial fission/fusion dynamics and apoptosis

(2010) Clare Sheridan et al.   MITOCHONDRION

Hippo signaling regulates Drosophila intestine stem cell proliferation through multiple pathways

(2010) F. Ren et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lifespan Extension by Preserving Proliferative Homeostasis in Drosophila

(2010) Benoît Biteau et al.   PLoS Genetics

Cytokine/Jak/Stat Signaling Mediates Regeneration and Homeostasis in the Drosophila Midgut

(2009) Huaqi Jiang et al.   CELL

Invasive and indigenous microbiota impact intestinal stem cell activity through multiple pathways in Drosophila

(2009) N. Buchon et al.   GENES & DEVELOPMENT

Reactive oxygen species prime Drosophila haematopoietic progenitors for differentiation

(2009) Edward Owusu-Ansah et al.   NATURE

Mitochondrial dynamics in model organisms: What yeasts, worms and flies have taught us about fusion and fission of mitochondria

(2009) Benedikt Westermann   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

JNK Activity in Somatic Stem Cells Causes Loss of Tissue Homeostasis in the Aging Drosophila Gut

(2008) Benoît Biteau et al.   Cell Stem Cell

Paracrine Wingless signalling controls self-renewal of Drosophila intestinal stem cells

(2008) Guonan Lin et al.   NATURE

Innate Immune Homeostasis by the Homeobox Gene Caudal and Commensal-Gut Mutualism in Drosophila

(2008) J.-H. Ryu et al.   SCIENCE