Integration of UPRER and Oxidative Stress Signaling in the Control of Intestinal Stem Cell Proliferation

PGRP-SC2 Promotes Gut Immune Homeostasis to Limit Commensal Dysbiosis and Extend Lifespan

(2014) Linlin Guo et al.   CELL

XBP-1 Is a Cell-Nonautonomous Regulator of Stress Resistance and Longevity

(2013) Rebecca C. Taylor et al.   CELL

ER stress transcription factor Xbp1 suppresses intestinal tumorigenesis and directs intestinal stem cells

(2013) Lukas Niederreiter et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Gut homeostasis in a microbial world: insights from Drosophila melanogaster

(2013) Nicolas Buchon et al.   NATURE REVIEWS MICROBIOLOGY

Drosophila XBP1 Expression Reporter Marks Cells under Endoplasmic Reticulum Stress and with High Protein Secretory Load

(2013) Hyung Don Ryoo et al.   PLoS One

ER Stress Causes Rapid Loss of Intestinal Epithelial Stemness through Activation of the Unfolded Protein Response

(2013) Jarom Heijmans et al.   Cell Reports

Integration of the Unfolded Protein and Oxidative Stress Responses through SKN-1/Nrf

(2013) Kira M. Glover-Cutter et al.   PLoS Genetics

A modified UPR stress sensing system reveals a novel tissue distribution of IRE1/XBP1 activity during normal Drosophila development

(2012) Michio Sone et al.   CELL STRESS & CHAPERONES

Balanced Ero1 activation and inactivation establishes ER redox homeostasis

(2012) Sunghwan Kim et al.   JOURNAL OF CELL BIOLOGY

The critical roles of endoplasmic reticulum chaperones and unfolded protein response in tumorigenesis and anticancer therapies

(2012) B Luo et al.   ONCOGENE

Intestinal barrier dysfunction links metabolic and inflammatory markers of aging to death in Drosophila

(2012) M. Rera et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Notch-Mediated Suppression of TSC2 Expression Regulates Cell Differentiation in the Drosophila Intestinal Stem Cell Lineage

(2012) Subir Kapuria et al.   PLoS Genetics

Redox Regulation by Keap1 and Nrf2 Controls Intestinal Stem Cell Proliferation in Drosophila

(2011) Christine E. Hochmuth et al.   Cell Stem Cell

Maintaining Tissue Homeostasis: Dynamic Control of Somatic Stem Cell Activity

(2011) Benoit Biteau et al.   Cell Stem Cell

EGF signaling regulates the proliferation of intestinal stem cells in Drosophila

(2011) B. Biteau et al.   DEVELOPMENT

Peroxiredoxin Stabilization of DE-Cadherin Promotes Primordial Germ Cell Adhesion

(2011) Matthew DeGennaro et al.   DEVELOPMENTAL CELL

Cellular stress response pathways and ageing: intricate molecular relationships

(2011) Nikos Kourtis et al.   EMBO JOURNAL

The unfolded protein response and its role in intestinal homeostasis and inflammation

(2011) Arthur Kaser et al.   EXPERIMENTAL CELL RESEARCH

The ER stress factor XBP1s prevents amyloid-β neurotoxicity

(2011) Sergio Casas-Tinto et al.   HUMAN MOLECULAR GENETICS

Road to Ruin: Targeting Proteins for Degradation in the Endoplasmic Reticulum

(2011) M. H. Smith et al.   SCIENCE

The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation

(2011) P. Walter et al.   SCIENCE

Aging as an Event of Proteostasis Collapse

(2011) R. C. Taylor et al.   Cold Spring Harbor Perspectives in Biology

Inflammatory Bowel Disease

(2010) Arthur Kaser et al.   Annual Review of Immunology

Homeostasis and Inflammation in the Intestine

(2010) Wendy S. Garrett et al.   CELL

Regulation of Drosophila lifespan by JNK signaling

(2010) Benoit Biteau et al.   EXPERIMENTAL GERONTOLOGY

Level of Activation of the Unfolded Protein Response Correlates With Paneth Cell Apoptosis in Human Small Intestine Exposed to Ischemia/Reperfusion

(2010) Joep Grootjans et al.   GASTROENTEROLOGY

Interference in xbp1 gene expression induces defective cell differentiation and sensory organ development in Drosophila

(2010) Gahee Choi et al.   Genes & Genomics

Characterization of midgut stem cell- and enteroblast-specific Gal4 lines in drosophila

(2010) Xiankun Zeng et al.   GENESIS

An essential role for XBP-1 in host protection against immune activation in C. elegans

(2010) Claire E. Richardson et al.   NATURE

Insulin/IGF-1 signaling mutants reprogram ER stress response regulators to promote longevity

(2010) S. Henis-Korenblit et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lifespan Extension by Preserving Proliferative Homeostasis in Drosophila

(2010) Benoît Biteau et al.   PLoS Genetics

XBP1: the last two decades

(2009) L H Glimcher   ANNALS OF THE RHEUMATIC DISEASES

Cytokine/Jak/Stat Signaling Mediates Regeneration and Homeostasis in the Drosophila Midgut

(2009) Huaqi Jiang et al.   CELL

Tissue Damage-Induced Intestinal Stem Cell Division in Drosophila

(2009) Alla Amcheslavsky et al.   Cell Stem Cell

Reactive oxygen species prime Drosophila haematopoietic progenitors for differentiation

(2009) Edward Owusu-Ansah et al.   NATURE

Suppression of retinal degeneration in Drosophila by stimulation of ER-associated degradation

(2009) M.-J. Kang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Age-related changes in Drosophila midgut are associated with PVF2, a PDGF/VEGF-like growth factor

(2008) Na-Hyun Choi et al.   AGING CELL

XBP1 Links ER Stress to Intestinal Inflammation and Confers Genetic Risk for Human Inflammatory Bowel Disease

(2008) Arthur Kaser et al.   CELL

JNK Activity in Somatic Stem Cells Causes Loss of Tissue Homeostasis in the Aging Drosophila Gut

(2008) Benoît Biteau et al.   Cell Stem Cell

Keap1/Nrf2 Signaling Regulates Oxidative Stress Tolerance and Lifespan in Drosophila

(2008) Gerasimos P. Sykiotis et al.   DEVELOPMENTAL CELL

Paracrine Wingless signalling controls self-renewal of Drosophila intestinal stem cells

(2008) Guonan Lin et al.   NATURE

Ero1 and redox homeostasis in the endoplasmic reticulum

(2007) Carolyn S. Sevier et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH