Polo-like kinase in trypanosomes: an odd member out of the Polo family

BOH1 cooperates with Polo-like kinase to regulate flagellum inheritance and cytokinesis initiation in Trypanosoma brucei

(2019) Kieu T. M. Pham et al.   JOURNAL OF CELL SCIENCE

The trypanosome-specific proteins FPRC and CIF4 regulate cytokinesis initiation by recruiting CIF1 to the cytokinesis initiation site

(2019) Huiqing Hu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Who Needs a Contractile Actomyosin Ring? The Plethora of Alternative Ways to Divide a Protozoan Parasite

(2019) Tansy C. Hammarton   Frontiers in Cellular and Infection Microbiology

Organising the cell cycle in the absence of transcriptional control: Dynamic phosphorylation co-ordinates the Trypanosoma brucei cell cycle post-transcriptionally

(2019) Corinna Benz et al.   PLoS Pathogens

Flagellum inheritance inTrypanosoma bruceirequires a kinetoplastid-specific protein phosphatase

(2018) Qing Zhou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The trypanosome-specific protein CIF3 cooperates with the CIF1 protein to promote cytokinesis inTrypanosoma brucei

(2018) Yasuhiro Kurasawa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of TOEFAZ1-interacting proteins reveals key regulators of Trypanosoma brucei cytokinesis

(2018) Nicholas A. Hilton et al.   MOLECULAR MICROBIOLOGY

The CIF1 protein is a master orchestrator of trypanosome cytokinesis that recruits several cytokinesis regulators to the cytokinesis-initiation site

(2018) Qing Zhou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The kinetoplastid kinetochore protein KKT4 is an unconventional microtubule tip–coupling protein

(2018) Aida Llauró et al.   JOURNAL OF CELL BIOLOGY

A functional analysis of TOEFAZ1 uncovers protein domains essential for cytokinesis inTrypanosoma brucei

(2017) Amy N. Sinclair-Davis et al.   JOURNAL OF CELL SCIENCE

Functional analyses of the CIF1–CIF2 complex in trypanosomes identify the structural motifs required for cytokinesis

(2017) Huiqing Hu et al.   JOURNAL OF CELL SCIENCE

Protein diversity in discrete structures at the distal tip of the trypanosome flagellum

(2017) Vladimir Varga et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome-wide and protein kinase-focused RNAi screens reveal conserved and novel damage response pathways in Trypanosoma brucei

(2017) Jennifer A. Stortz et al.   PLoS Pathogens

CRL4WDR1 Controls Polo-like Kinase Protein Abundance to Promote Bilobe Duplication, Basal Body Segregation and Flagellum Attachment in Trypanosoma brucei

(2017) Huiqing Hu et al.   PLoS Pathogens

The PLK4–STIL–SAS-6 module at the core of centriole duplication

(2016) Christian Arquint et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

An EF-hand-containing Protein inTrypanosoma bruceiRegulates Cytokinesis Initiation by Maintaining the Stability of the Cytokinesis Initiation Factor CIF1

(2016) Qing Zhou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Trypanosome outer kinetochore proteins suggest conservation of chromosome segregation machinery across eukaryotes

(2016) Simon D’Archivio et al.   JOURNAL OF CELL BIOLOGY

Two distinct cytokinesis pathways drive trypanosome cell division initiation from opposite cell ends

(2016) Qing Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Divergent polo box domains underpin the unique kinetoplastid kinetochore

(2016) Olga O. Nerusheva et al.   Open Biology

The Centriole Cartwheel Protein SAS-6 in Trypanosoma brucei Is Required for Probasal Body Biogenesis and Flagellum Assembly

(2015) Huiqing Hu et al.   EUKARYOTIC CELL

A Novel Basal Body Protein That Is a Polo-like Kinase Substrate Is Required for Basal Body Segregation and Flagellum Adhesion inTrypanosoma brucei

(2015) Huiqing Hu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Assembly and maintenance of the flagellum attachment zone filament in Trypanosoma brucei

(2015) Q. Zhou et al.   JOURNAL OF CELL SCIENCE

Proteomic identification of novel cytoskeletal proteins associated with TbPLK, an essential regulator of cell morphogenesis in Trypanosoma brucei

(2015) Michael R. McAllaster et al.   MOLECULAR BIOLOGY OF THE CELL

Discovery of Unconventional Kinetochores in Kinetoplastids

(2014) Bungo Akiyoshi et al.   CELL

The Eukaryotic Tree of Life from a Global Phylogenomic Perspective

(2014) F. Burki   Cold Spring Harbor Perspectives in Biology

Flagellar adhesion in Trypanosoma brucei relies on interactions between different skeletal structures in the flagellum and cell body

(2013) B. Rotureau et al.   JOURNAL OF CELL SCIENCE

Polo-like kinase phosphorylation of bilobe-resident TbCentrin2 facilitates flagellar inheritance in Trypanosoma brucei

(2013) Christopher L. de Graffenried et al.   MOLECULAR BIOLOGY OF THE CELL

An analogue-sensitive approach identifies basal body rotation and flagellum attachment zone elongation as key functions of PLK in Trypanosoma brucei

(2013) Ana Lozano-Núñez et al.   MOLECULAR BIOLOGY OF THE CELL

Cytokinesis inTrypanosoma bruceidiffers between bloodstream and tsetse trypomastigote forms: implications for microtubule-based morphogenesis and mutant analysis

(2013) Richard J. Wheeler et al.   MOLECULAR MICROBIOLOGY

Structural basis for the inhibition of Polo-like kinase 1

(2013) Jun Xu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Evolutionary cell biology of chromosome segregation: insights from trypanosomes

(2013) B. Akiyoshi et al.   Open Biology

Morphology of the Trypanosome Bilobe, a Novel Cytoskeletal Structure

(2012) Heather J. Esson et al.   EUKARYOTIC CELL

Regulation of the Cell Division Cycle in Trypanosoma brucei

(2012) Ziyin Li   EUKARYOTIC CELL

An intracellular membrane junction consisting of flagellum adhesion glycoproteins links flagellum biogenesis to cell morphogenesis in Trypanosoma brucei

(2012) S. Y. Sun et al.   JOURNAL OF CELL SCIENCE

Structure-function relationship of the Polo-like kinase in Trypanosoma brucei

(2012) Z. Yu et al.   JOURNAL OF CELL SCIENCE

Polo-like kinase is necessary for flagellum inheritance in Trypanosoma brucei

(2012) Kyojiro N. Ikeda et al.   JOURNAL OF CELL SCIENCE

The Chromosomal Passenger Complex Activates Polo Kinase at Centromeres

(2012) Mar Carmena et al.   PLOS BIOLOGY

From Plk1 to Plk5

(2011) Guillermo de Cárcer et al.   CELL CYCLE

High-throughput phenotyping using parallel sequencing of RNA interference targets in the African trypanosome

(2011) S. Alsford et al.   GENOME RESEARCH

A coiled-coil- and C2-domain-containing protein is required for FAZ assembly and cell morphology in Trypanosoma brucei

(2011) Q. Zhou et al.   JOURNAL OF CELL SCIENCE

Plk5, a Polo Box Domain-Only Protein with Specific Roles in Neuron Differentiation and Glioblastoma Suppression

(2011) G. de Carcer et al.   MOLECULAR AND CELLULAR BIOLOGY

Formation of stable attachments between kinetochores and microtubules depends on the B56-PP2A phosphatase

(2011) Emily A. Foley et al.   NATURE CELL BIOLOGY

Polo-Like Kinase Guides Cytokinesis in Trypanosoma brucei through an Indirect Means

(2010) Zhi Li et al.   EUKARYOTIC CELL

Polo-like kinase 4 kinase activity limits centrosome overduplication by autoregulating its own stability

(2010) Andrew J. Holland et al.   JOURNAL OF CELL BIOLOGY

Plk4 trans-autophosphorylation regulates centriole number by controlling  TrCP-mediated degradation

(2010) G. Guderian et al.   JOURNAL OF CELL SCIENCE

Basal body movements orchestrate membrane organelle division and cell morphogenesis in Trypanosoma brucei

(2010) S. Lacomble et al.   JOURNAL OF CELL SCIENCE

A Comparative Proteomic Analysis Reveals a New Bi-Lobe Protein Required for Bi-Lobe Duplication and Cell Division in Trypanosoma brucei

(2010) Qing Zhou et al.   PLoS One

The SCFSlimbubiquitin ligase regulates Plk4/Sak levels to block centriole reduplication

(2009) Gregory C. Rogers et al.   JOURNAL OF CELL BIOLOGY

The Phosphoproteome of Bloodstream FormTrypanosoma brucei, Causative Agent of African Sleeping Sickness

(2009) Isabelle R. E. Nett et al.   MOLECULAR & CELLULAR PROTEOMICS

The bilobe structure of Trypanosoma brucei contains a MORN-repeat protein

(2009) Brooke Morriswood et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Polo-like kinases: conservation and divergence in their functions and regulation

(2009) Vincent Archambault et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The Aurora Kinase in Trypanosoma brucei Plays Distinctive Roles in Metaphase-Anaphase Transition and Cytokinetic Initiation

(2009) Ziyin Li et al.   PLoS Pathogens

The SCF/Slimb Ubiquitin Ligase Limits Centrosome Amplification through Degradation of SAK/PLK4

(2008) Inês Cunha-Ferreira et al.   CURRENT BIOLOGY

Polo on the Rise—from Mitotic Entry to Cytokinesis with Plk1

(2008) Mark Petronczki et al.   DEVELOPMENTAL CELL

Myosin Phosphatase-Targeting Subunit 1 Regulates Mitosis by Antagonizing Polo-like Kinase 1

(2008) Shigeko Yamashiro et al.   DEVELOPMENTAL CELL

Polo-Like Kinase Is Expressed in S/G2/M Phase and Associated with the Flagellum Attachment Zone in both Procyclic and Bloodstream Forms ofTrypanosoma brucei

(2008) Takashi Umeyama et al.   EUKARYOTIC CELL

Polo-like kinase is required for Golgi and bilobe biogenesis inTrypanosoma brucei

(2008) Christopher L. de Graffenried et al.   JOURNAL OF CELL BIOLOGY

Polo-like kinase-1 is activated by aurora A to promote checkpoint recovery

(2008) Libor Macůrek et al.   NATURE

Identification of a Novel Chromosomal Passenger Complex and Its Unique Localization during Cytokinesis in Trypanosoma brucei

(2008) Ziyin Li et al.   PLoS One

The Chromosomal Passenger Complex and a Mitotic Kinesin Interact with the Tousled-Like Kinase in Trypanosomes to Regulate Mitosis and Cytokinesis

(2008) Ziyin Li et al.   PLoS One

Bora and the Kinase Aurora A Cooperatively Activate the Kinase Plk1 and Control Mitotic Entry

(2008) A. Seki et al.   SCIENCE

Biogenesis of the Trypanosome Endo-Exocytotic Organelle Is Cytoskeleton Mediated

(2008) Mélanie Bonhivers et al.   PLOS BIOLOGY

A Repetitive Protein Essential for the Flagellum Attachment Zone Filament Structure and Function in Trypanosoma brucei

(2007) Sue Vaughan et al.   PROTIST