Proteomic identification of novel cytoskeletal proteins associated with TbPLK, an essential regulator of cell morphogenesis in Trypanosoma brucei

A dynamic coordination of flagellum and cytoplasmic cytoskeleton assembly specifies cell morphogenesis in trypanosomes

(2015) J. D. Sunter et al.   JOURNAL OF CELL SCIENCE

Modulation of a cytoskeletal calpain-like protein induces major transitions in trypanosome morphology

(2014) Polly Hayes et al.   JOURNAL OF CELL BIOLOGY

Motility and more: the flagellum of Trypanosoma brucei

(2014) Gerasimos Langousis et al.   NATURE REVIEWS MICROBIOLOGY

Polo-like kinases: structural variations lead to multiple functions

(2014) Sihem Zitouni et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The tubulin cofactor C family member TBCCD1 orchestrates cytoskeletal filament formation

(2013) J. Andre et al.   JOURNAL OF CELL SCIENCE

A cell-body groove housing the new flagellum tip suggests an adaptation of cellular morphogenesis for parasitism in the bloodstream form of Trypanosoma brucei

(2013) Louise Hughes et al.   JOURNAL OF CELL SCIENCE

Global Quantitative SILAC Phosphoproteomics Reveals Differential Phosphorylation Is Widespread between the Procyclic and Bloodstream Form Lifecycle Stages of Trypanosoma brucei

(2013) Michael D. Urbaniak et al.   JOURNAL OF PROTEOME RESEARCH

A Protein Phosphatase 1 involved in correct nucleus positioning in trypanosomes

(2013) Cécile Gallet et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Polo-like kinase phosphorylation of bilobe-resident TbCentrin2 facilitates flagellar inheritance in Trypanosoma brucei

(2013) Christopher L. de Graffenried et al.   MOLECULAR BIOLOGY OF THE CELL

An analogue-sensitive approach identifies basal body rotation and flagellum attachment zone elongation as key functions of PLK in Trypanosoma brucei

(2013) Ana Lozano-Núñez et al.   MOLECULAR BIOLOGY OF THE CELL

Glossina fuscipes populations provide insights for human African trypanosomiasis transmission in Uganda

(2013) Serap Aksoy et al.   TRENDS IN PARASITOLOGY

A new asymmetric division contributes to the continuous production of infective trypanosomes in the tsetse fly

(2012) B. Rotureau et al.   DEVELOPMENT

Ciliary and Nuclear Transport: Different Places, Similar Routes?

(2012) Samson O. Obado et al.   DEVELOPMENTAL CELL

Morphology of the Trypanosome Bilobe, a Novel Cytoskeletal Structure

(2012) Heather J. Esson et al.   EUKARYOTIC CELL

Novel Bilobe Components in Trypanosoma brucei Identified Using Proximity-Dependent Biotinylation

(2012) Brooke Morriswood et al.   EUKARYOTIC CELL

Biochemical Characterization of the Bi-lobe Reveals a Continuous Structural Network Linking the Bi-lobe to Other Single-copied Organelles inTrypanosoma brucei

(2012) Ladan Gheiratmand et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A promiscuous biotin ligase fusion protein identifies proximal and interacting proteins in mammalian cells

(2012) Kyle J. Roux et al.   JOURNAL OF CELL BIOLOGY

Structure-function relationship of the Polo-like kinase in Trypanosoma brucei

(2012) Z. Yu et al.   JOURNAL OF CELL SCIENCE

Polo-like kinase is necessary for flagellum inheritance in Trypanosoma brucei

(2012) Kyojiro N. Ikeda et al.   JOURNAL OF CELL SCIENCE

Mass spectrometry approaches to study mammalian kinase and phosphatase associated proteins

(2012) Michelle J. Kean et al.   METHODS

A size-exclusion permeability barrier and nucleoporins characterize a ciliary pore complex that regulates transport into cilia

(2012) Hooi Lynn Kee et al.   NATURE CELL BIOLOGY

Comparative SILAC Proteomic Analysis of Trypanosoma brucei Bloodstream and Procyclic Lifecycle Stages

(2012) Michael D. Urbaniak et al.   PLoS One

NUP-1 Is a Large Coiled-Coil Nucleoskeletal Protein in Trypanosomes with Lamin-Like Functions

(2012) Kelly N. DuBois et al.   PLOS BIOLOGY

Transmission Stages Dominate Trypanosome Within-Host Dynamics during Chronic Infections

(2011) Paula MacGregor et al.   Cell Host & Microbe

A coiled-coil- and C2-domain-containing protein is required for FAZ assembly and cell morphology in Trypanosoma brucei

(2011) Q. Zhou et al.   JOURNAL OF CELL SCIENCE

A Gateway® compatible vector for gene silencing in bloodstream form Trypanosoma brucei

(2011) Savitha Kalidas et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Plk1-targeted small molecule inhibitors: molecular basis for their potency and specificity

(2011) Ravichandran N. Murugan et al.   MOLECULES AND CELLS

The Cell Cycle Regulated Transcriptome of Trypanosoma brucei

(2011) Stuart K. Archer et al.   PLoS One

Quantitative Mass Spectrometry Analysis Reveals Similar Substrate Consensus Motif for Human Mps1 Kinase and Plk1

(2011) Zhen Dou et al.   PLoS One

Targeting Cattle-Borne Zoonoses and Cattle Pathogens Using a Novel Trypanosomatid-Based Delivery System

(2011) G. Adam Mott et al.   PLoS Pathogens

Assembly of the flagellum and its role in cell morphogenesis in Trypanosoma brucei

(2010) Sue Vaughan   CURRENT OPINION IN MICROBIOLOGY

Plk1 negatively regulates Cep55 recruitment to the midbody to ensure orderly abscission

(2010) Ricardo Nunes Bastos et al.   JOURNAL OF CELL BIOLOGY

Basal body movements orchestrate membrane organelle division and cell morphogenesis in Trypanosoma brucei

(2010) S. Lacomble et al.   JOURNAL OF CELL SCIENCE

A Comparative Proteomic Analysis Reveals a New Bi-Lobe Protein Required for Bi-Lobe Duplication and Cell Division in Trypanosoma brucei

(2010) Qing Zhou et al.   PLoS One

Human innate immunity against African trypanosomes

(2009) Etienne Pays et al.   CURRENT OPINION IN IMMUNOLOGY

Three-dimensional cellular architecture of the flagellar pocket and associated cytoskeleton in trypanosomes revealed by electron microscope tomography

(2009) S. Lacomble et al.   JOURNAL OF CELL SCIENCE

Human African trypanosomiasis

(2009) Reto Brun et al.   LANCET

The bilobe structure of Trypanosoma brucei contains a MORN-repeat protein

(2009) Brooke Morriswood et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Universal sample preparation method for proteome analysis

(2009) Jacek R Wiśniewski et al.   NATURE METHODS

The trypanosome flagellar pocket

(2009) Mark C. Field et al.   NATURE REVIEWS MICROBIOLOGY

Polo-like kinases: conservation and divergence in their functions and regulation

(2009) Vincent Archambault et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Structural and functional analyses of minimal phosphopeptides targeting the polo-box domain of polo-like kinase 1

(2009) Sang-Moon Yun et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Membrane domains and flagellar pocket boundaries are influenced by the cytoskeleton in African trypanosomes

(2009) C. Gadelha et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Burden of Human African Trypanosomiasis

(2009) Eric M. Fèvre et al.   PLoS Neglected Tropical Diseases

The Aurora Kinase in Trypanosoma brucei Plays Distinctive Roles in Metaphase-Anaphase Transition and Cytokinetic Initiation

(2009) Ziyin Li et al.   PLoS Pathogens

KMP-11, a Basal Body and Flagellar Protein, Is Required for Cell Division inTrypanosoma brucei

(2008) Ziyin Li et al.   EUKARYOTIC CELL

Polo-like kinase is required for Golgi and bilobe biogenesis inTrypanosoma brucei

(2008) Christopher L. de Graffenried et al.   JOURNAL OF CELL BIOLOGY

Identification of a Novel Chromosomal Passenger Complex and Its Unique Localization during Cytokinesis in Trypanosoma brucei

(2008) Ziyin Li et al.   PLoS One

The Chromosomal Passenger Complex and a Mitotic Kinesin Interact with the Tousled-Like Kinase in Trypanosomes to Regulate Mitosis and Cytokinesis

(2008) Ziyin Li et al.   PLoS One

Using Engineered Scaffold Interactions to Reshape MAP Kinase Pathway Signaling Dynamics

(2008) C. J. Bashor et al.   SCIENCE

Biogenesis of the Trypanosome Endo-Exocytotic Organelle Is Cytoskeleton Mediated

(2008) Mélanie Bonhivers et al.   PLOS BIOLOGY

Asymmetric Cell Division as a Route to Reduction in Cell Length and Change in Cell Morphology in Trypanosomes

(2007) Reuben Sharma et al.   PROTIST

A Repetitive Protein Essential for the Flagellum Attachment Zone Filament Structure and Function in Trypanosoma brucei

(2007) Sue Vaughan et al.   PROTIST