IL-17A is implicated in lipopolysaccharide-induced neuroinflammation and cognitive impairment in aged rats via microglial activation

Alterations in microglial phenotype and hippocampal neuronal function in transgenic mice with astrocyte-targeted production of interleukin-10

(2015) Beatriz Almolda et al.   BRAIN BEHAVIOR AND IMMUNITY

S100A8 contributes to postoperative cognitive dysfunction in mice undergoing tibial fracture surgery by activating the TLR4/MyD88 pathway

(2015) Shun-Mei Lu et al.   BRAIN BEHAVIOR AND IMMUNITY

Histone Deacetylase Inhibitor Trichostatin A Ameliorated Endotoxin-Induced Neuroinflammation and Cognitive Dysfunction

(2015) Chung-Hsi Hsing et al.   MEDIATORS OF INFLAMMATION

Bee Venom Acupuncture Alleviates Experimental Autoimmune Encephalomyelitis by Upregulating Regulatory T Cells and Suppressing Th1 and Th17 Responses

(2015) Min Jung Lee et al.   MOLECULAR NEUROBIOLOGY

The evolution of amidine-based brain penetrant BACE1 inhibitors

(2014) Daniel Oehlrich et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Effector molecules released by Th1 but not Th17 cells drive an M1 response in microglia

(2014) Chittappen K. Prajeeth et al.   BRAIN BEHAVIOR AND IMMUNITY

Vitamin D Improves Cognitive Function and Modulates Th17/Treg Cell Balance After Hepatectomy in Mice

(2014) Ayong Tian et al.   INFLAMMATION

Interleukin-17 (IL-17)-induced MicroRNA 873 (miR-873) Contributes to the Pathogenesis of Experimental Autoimmune Encephalomyelitis by Targeting A20 Ubiquitin-editing Enzyme

(2014) Xiaomei Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lithium ameliorates lipopolysaccharide-induced microglial activation via inhibition of toll-like receptor 4 expression by activating the PI3K/Akt/FoxO1 pathway

(2014) Hongquan Dong et al.   Journal of Neuroinflammation

Blocking Lymphocyte Trafficking with FTY720 Prevents Inflammation-Sensitized Hypoxic–Ischemic Brain Injury in Newborns

(2014) Dianer Yang et al.   JOURNAL OF NEUROSCIENCE

The Role of IL-17 Promotes Spinal Cord Neuroinflammation via Activation of the Transcription Factor STAT3 after Spinal Cord Injury in the Rat

(2014) Shaohui Zong et al.   MEDIATORS OF INFLAMMATION

Poststroke Neuropsychiatric Symptoms: Relationships with IL-17 and Oxidative Stress

(2014) W. Swardfager et al.   Biomed Research International

Surgery Results in Exaggerated and Persistent Cognitive Decline in a Rat Model of the Metabolic Syndrome

(2013) Xiaomei Feng et al.   ANESTHESIOLOGY

Neuroprotection effect of interleukin (IL)-17 secreted by reactive astrocytes is emerged from a high-level IL-17-containing environment during acute neuroinflammation

(2013) M. H. Hu et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Monophosphoryl lipid A is an lipopolysaccharide-derived Toll-like receptor 4 agonist which may improve Alzheimer's disease pathology

(2013) David B Wang   EXPERT OPINION ON BIOLOGICAL THERAPY

Furanodien-6-one from Commiphora erythraea inhibits the NF-κB signalling and attenuates LPS-induced neuroinflammation

(2013) Ilaria Bellezza et al.   MOLECULAR IMMUNOLOGY

Aging enhances classical activation but mitigates alternative activation in the central nervous system

(2013) Daniel C. Lee et al.   NEUROBIOLOGY OF AGING

Respiratory infection promotes T cell infiltration and amyloid-β deposition in APP/PS1 mice

(2013) Róisín M. McManus et al.   NEUROBIOLOGY OF AGING

CNS-Targeted Production of IL-17A Induces Glial Activation, Microvascular Pathology and Enhances the Neuroinflammatory Response to Systemic Endotoxemia

(2013) Julian Zimmermann et al.   PLoS One

Neutralization of the IL-17 axis diminishes neutrophil invasion and protects from ischemic stroke

(2012) M. Gelderblom et al.   BLOOD

Molecular Mechanisms and Therapeutic Application of NSAIDs and Derived Compounds in Alzheimers Disease

(2012) M. T. Heneka et al.   Current Alzheimer Research

Inhibitory effect of 4-O-methylhonokiol on lipopolysaccharide-induced neuroinflammation, amyloidogenesis and memory impairment via inhibition of nuclear factor-kappaB in vitro and in vivo models

(2012) Young-Jung Lee et al.   Journal of Neuroinflammation

Epigallocatechin-3-gallate prevents systemic inflammation-induced memory deficiency and amyloidogenesis via its anti-neuroinflammatory properties

(2012) Young-Jung Lee et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Review: Microglia of the aged brain: primed to be activated and resistant to regulation

(2012) D. M. Norden et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

The γ-secretase blocker DAPT impairs recovery from lipopolysaccharide-induced inflammation in rat brain

(2012) S. Nasoohi et al.   NEUROSCIENCE

Microglial physiopathology: how to explain the dual role of microglia after acute neural disorders?

(2012) Walace Gomes-Leal   Brain and Behavior

HO-1–STAT3 axis in mouse liver ischemia/reperfusion injury: Regulation of TLR4 innate responses through PI3K/PTEN signaling

(2011) Bibo Ke et al.   JOURNAL OF HEPATOLOGY

Neuroinflammation in Parkinson's disease

(2011) Etienne C. Hirsch et al.   PARKINSONISM & RELATED DISORDERS

Inflammation and Alzheimer’s disease

(2010) Young-Jung Lee et al.   ARCHIVES OF PHARMACAL RESEARCH

Infiltration of Th1 and Th17 cells and activation of microglia in the CNS during the course of experimental autoimmune encephalomyelitis

(2010) Áine C. Murphy et al.   BRAIN BEHAVIOR AND IMMUNITY

Agmatine prevents LPS-induced spatial memory impairment and hippocampal apoptosis

(2010) Asadollah Zarifkar et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Tumor necrosis factor-  triggers a cytokine cascade yielding postoperative cognitive decline

(2010) N. Terrando et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neuroinflammation and Cognitive Aging

(2010) Raymond L. Ownby   Current Psychiatry Reports

The Role of Neuroimmunomodulation in Alzheimer's Disease

(2009) Ricardo B. Maccioni et al.   Annals of the New York Academy of Sciences

Pivotal role of cerebral interleukin-17–producing γδT cells in the delayed phase of ischemic brain injury

(2009) Takashi Shichita et al.   NATURE MEDICINE

Beta-Secretase: Structure, Function, and Evolution

(2008) Chitra Venugopal et al.   CNS & Neurological Disorders-Drug Targets

Adverse functions of IL-17A in experimental sepsis

(2008) Michael A. Flierl et al.   FASEB JOURNAL

Production and functions of IL-17 in microglia

(2008) Jun Kawanokuchi et al.   JOURNAL OF NEUROIMMUNOLOGY

Increased systemic and brain cytokine production and neuroinflammation by endotoxin following ethanol treatment

(2008) Liya Qin et al.   Journal of Neuroinflammation

Neuro-inflammation induced by lipopolysaccharide causes cognitive impairment through enhancement of beta-amyloid generation

(2008) Jae Lee et al.   Journal of Neuroinflammation