Docosahexaenoic Acid, a Potential Treatment for Sarcopenia, Modulates the Ubiquitin–Proteasome and the Autophagy–Lysosome Systems

Mechanism of increased risk of insulin resistance in aging skeletal muscle

(2020) Jian Shou et al.   Diabetology & Metabolic Syndrome

Novel Insights on Intake of Fish and Prevention of Sarcopenia: All Reasons for an Adequate Consumption

(2020) Mariangela Rondanelli et al.   Nutrients

Physical Exercise and Myokines: Relationships with Sarcopenia and Cardiovascular Complications

(2020) Sandra Maria Barbalho et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

TNF Receptor‐Associated Factor 6 Mediates TNFα ‐Induced Skeletal Muscle Atrophy in Mice During Aging

(2020) Jinbo Li et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Health Consequences of Sarcopenic Obesity: A Narrative Review

(2020) Eun Roh et al.   Frontiers in Endocrinology

Negative-feedback coordination between proteasomal activity and autophagic flux

(2019) Jung Hoon Lee et al.   Autophagy

Serum Myostatin and IGF-1 as Gender-Specific Biomarkers of Frailty and Low Muscle Mass in Community-Dwelling Older Adults

(2019) Justin Chew et al.   Journal of Nutrition Health & Aging

Rapamycin for longevity: opinion article

(2019) Mikhail V. Blagosklonny   Aging-US

Effects of Aging and Lifelong Aerobic Exercise on Basal and Exercise-Induced Inflammation

(2019) Kaleen M. Lavin et al.   JOURNAL OF APPLIED PHYSIOLOGY

Regulatory role of exercise-induced autophagy for sarcopenia

(2019) Jiling Liang et al.   EXPERIMENTAL GERONTOLOGY

Control of Inflammation by Calorie Restriction Mimetics: On the Crossroad of Autophagy and Mitochondria

(2019) Enrique Gabandé-Rodríguez et al.   Cells

Molecular Insights into Muscle Homeostasis, Atrophy and Wasting

(2018) Bianca Maria Scicchitano et al.   CURRENT GENOMICS

Autophagy as a promoter of longevity: insights from model organisms

(2018) Malene Hansen et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Potential Roles of n-3 PUFAs during Skeletal Muscle Growth and Regeneration

(2018) Bill Tachtsis et al.   Nutrients

Dual Function of USP14 Deubiquitinase in Cellular Proteasomal Activity and Autophagic Flux

(2018) Eunkyoung Kim et al.   Cell Reports

OUP accepted manuscript

(2018)   AGE AND AGEING

Pharmacological Interventions to Improve Muscle Mass, Muscle Strength and Physical Performance in Older People: An Umbrella Review of Systematic Reviews and Meta-analyses

(2018) Anton De Spiegeleer et al.   DRUGS & AGING

Impaired proteostasis during skeletal muscle aging

(2018) Raquel Fernando et al.   FREE RADICAL BIOLOGY AND MEDICINE

Effects of exercise and nutrition supplementation in community-dwelling older Chinese people with sarcopenia: a randomized controlled trial

(2018) Liu-Ying Zhu et al.   AGE AND AGEING

Sarcopenia in hiding: The risk and consequence of underestimating muscle dysfunction in nonalcoholic steatohepatitis

(2017) Rahima A. Bhanji et al.   HEPATOLOGY

Recent advances in pharmacological, hormonal, and nutritional intervention for sarcopenia

(2017) Kunihiro Sakuma et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Molecular mechanism of sarcopenia and cachexia: recent research advances

(2017) Kunihiro Sakuma et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

The Role of Inflammation in Age-Related Sarcopenia

(2017) Sebastiaan Dalle et al.   Frontiers in Physiology

Sex differences in the effect of fish-oil supplementation on the adaptive response to resistance exercise training in older people: a randomized controlled trial

(2016) Mariasole Da Boit et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

The ubiquitin proteasome system in atrophying skeletal muscle: roles and regulation

(2016) Philippe A. Bilodeau et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Docosahexaenoic Acid

(2016) Philip C. Calder   ANNALS OF NUTRITION AND METABOLISM

The arginylation branch of the N-end rule pathway positively regulates cellular autophagic flux and clearance of proteotoxic proteins

(2016) Yanxialei Jiang et al.   Autophagy

Akt/mTOR pathway contributes to skeletal muscle anti-atrophic effect of aerobic exercise training in heart failure mice

(2016) Aline V.N. Bacurau et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Open-gate mutants of the mammalian proteasome show enhanced ubiquitin-conjugate degradation

(2016) Won Hoon Choi et al.   Nature Communications

Docosahexaenoic acid-supplementation prior to fasting prevents muscle atrophy in mice

(2016) Christiane Deval et al.   Journal of Cachexia Sarcopenia and Muscle

Differences among skeletal muscle mass indices derived from height-, weight-, and body mass index-adjusted models in assessing sarcopenia

(2016) Kyoung Min Kim et al.   KOREAN JOURNAL OF INTERNAL MEDICINE

Denervation-Induced Activation of the Standard Proteasome and Immunoproteasome

(2016) Haiming M. Liu et al.   PLoS One

Proteasome activation: An innovative promising approach for delaying aging and retarding age-related diseases

(2015) Niki Chondrogianni et al.   AGEING RESEARCH REVIEWS

Fish oil–derived n−3 PUFA therapy increases muscle mass and function in healthy older adults1

(2015) Gordon I Smith et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Insulin-like growth factor-1 suppresses the Myostatin signaling pathway during myogenic differentiation

(2015) A. Retamales et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Autophagy as a Potential Target for Sarcopenia

(2015) Jingjing Fan et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Omega-3 Fatty Acids and Skeletal Muscle Health

(2015) Stewart Jeromson et al.   Marine Drugs

p62/SQSTM1 but not LC3 is accumulated in sarcopenic muscle of mice

(2015) Kunihiro Sakuma et al.   Journal of Cachexia Sarcopenia and Muscle

Skeletal muscle wasting in cachexia and sarcopenia: molecular pathophysiology and impact of exercise training

(2015) T. Scott Bowen et al.   Journal of Cachexia Sarcopenia and Muscle

Skeletal muscle atrophy and the E3 ubiquitin ligases MuRF1 and MAFbx/atrogin-1

(2014) Sue C. Bodine et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Protein intake and exercise for optimal muscle function with aging: Recommendations from the ESPEN Expert Group

(2014) Nicolaas E.P. Deutz et al.   CLINICAL NUTRITION

Proteasome dysfunction induces muscle growth defects and protein aggregation

(2014) Y. Kitajima et al.   JOURNAL OF CELL SCIENCE

Docosahexaenoic acid prevents palmitate-induced activation of proteolytic systems in C2C12 myotubes

(2014) Myra E. Woodworth-Hobbs et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Maintenance of muscle mass and load-induced growth in Muscle RING Finger 1 null mice with age

(2013) Darren T. Hwee et al.   AGING CELL

The effect of eicosapentaenoic and docosahexaenoic acid on protein synthesis and breakdown in murine C2C12 myotubes

(2013) Torkamol Kamolrat et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Hallmarks of Aging

(2013) Carlos López-Otín et al.   CELL

Mechanisms of muscle growth and atrophy in mammals andDrosophila

(2013) Rosanna Piccirillo et al.   DEVELOPMENTAL DYNAMICS

Mechanisms regulating skeletal muscle growth and atrophy

(2013) Stefano Schiaffino et al.   FEBS Journal

Protein breakdown in muscle wasting: Role of autophagy-lysosome and ubiquitin-proteasome

(2013) Marco Sandri   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Tau degradation: The ubiquitin–proteasome system versus the autophagy-lysosome system

(2013) Min Jae Lee et al.   PROGRESS IN NEUROBIOLOGY

The Omega-3 Polyunsaturated Fatty Acid DHA Induces Simultaneous Apoptosis and Autophagy via Mitochondrial ROS-Mediated Akt-mTOR Signaling in Prostate Cancer Cells Expressing Mutant p53

(2013) Soyeon Shin et al.   Biomed Research International

Fish-oil supplementation enhances the effects of strength training in elderly women

(2012) Cintia LN Rodacki et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Identification of atrogin-1-targeted proteins during the myostatin-induced skeletal muscle wasting

(2012) Sudarsanareddy Lokireddy et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Adaptive plasticity of autophagic proteins to denervation in aging skeletal muscle

(2012) Michael F. O'Leary et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

The p97/VCP ATPase is critical in muscle atrophy and the accelerated degradation of muscle proteins

(2012) Rosanna Piccirillo et al.   EMBO JOURNAL

Upregulation of proteasome activity in muscle RING finger 1-null mice following denervation

(2012) Aldrin V. Gomes et al.   FASEB JOURNAL

The Effect of Physiological Stimuli on Sarcopenia; Impact of Notch and Wnt Signaling on Impaired Aged Skeletal Muscle Repair

(2012) Susan Tsivitse Arthur et al.   International Journal of Biological Sciences

The impact of supplemental N-3 long chain polyunsaturated fatty acids and dietary antioxidants on physical performance in postmenopausal women

(2012) H. L. Hutchins-Wiese et al.   Journal of Nutrition Health & Aging

Docosahexaenoic acid induces autophagy through p53/AMPK/mTOR signaling and promotes apoptosis in human cancer cells harboring wild-type p53

(2011) Kaipeng Jing et al.   Autophagy

Regulation of p97 in the ubiquitin–proteasome system by the UBX protein-family

(2011) Patrik Kloppsteck et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The proteasome inhibitor MG132 reduces immobilization-induced skeletal muscle atrophy in mice

(2011) Annabelle Z Caron et al.   BMC MUSCULOSKELETAL DISORDERS

Muscle sparing in muscle RING finger 1 null mice: response to synthetic glucocorticoids

(2011) Leslie M. Baehr et al.   JOURNAL OF PHYSIOLOGY-LONDON

Exercise, Amino Acids, and Aging in the Control of Human Muscle Protein Synthesis

(2011) DILLON K. WALKER et al.   MEDICINE AND SCIENCE IN SPORTS AND EXERCISE

Prevention of muscle disuse atrophy by MG132 proteasome inhibitor

(2011) Cecile Jamart et al.   MUSCLE & NERVE

Skeletal muscle protein metabolism in the elderly: Interventions to counteract the 'anabolic resistance' of ageing

(2011) Leigh Breen et al.   Nutrition & Metabolism

Models of accelerated sarcopenia: Critical pieces for solving the puzzle of age-related muscle atrophy

(2010) Thomas W. Buford et al.   AGEING RESEARCH REVIEWS

Dietary omega-3 fatty acid supplementation increases the rate of muscle protein synthesis in older adults: a randomized controlled trial

(2010) Gordon I Smith et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Suppression of autophagy permits successful enzyme replacement therapy in a lysosomal storage disorder—murine Pompe disease

(2010) Nina Raben et al.   Autophagy

EPA inhibits the inhibitor of κBα (IκBα)/NF-κB/muscle RING finger 1 pathway in C2C12 myotubes in a PPARγ-dependent manner

(2010) Feiruo Huang et al.   BRITISH JOURNAL OF NUTRITION

Sarcopenia: characteristics, mechanisms and functional significance

(2010) M. V. Narici et al.   BRITISH MEDICAL BULLETIN

Antibody-directed myostatin inhibition in 21-mo-old mice reveals novel roles for myostatin signaling in skeletal muscle structure and function

(2010) Kate T. Murphy et al.   FASEB JOURNAL

Muscle Wasting in Aged, Sarcopenic Rats Is Associated with Enhanced Activity of the Ubiquitin Proteasome Pathway

(2010) Mikael Altun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Modulation of Muscle Atrophy, Fatigue and MLC Phosphorylation by MuRF1 as Indicated by Hindlimb Suspension Studies on MuRF1-KO Mice

(2010) Siegfried Labeit et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Membrane lipid modification by polyunsaturated fatty acids sensitizes oligodendroglial OLN-93 cells against oxidative stress and promotes up-regulation of heme oxygenase-1 (HSP32)

(2010) Annette Brand et al.   JOURNAL OF NEUROCHEMISTRY

Proteasomal activity in skeletal muscle: A matter of assay design, muscle type, and age

(2009) Karl-Heinz Strucksberg et al.   ANALYTICAL BIOCHEMISTRY

Alpha-linolenic acid supplementation and resistance training in older adults

(2009) Stephen M. Cornish et al.   Applied Physiology Nutrition and Metabolism

Isolation of Mammalian 26S Proteasomes and p97/VCP Complexes Using the Ubiquitin-like Domain from HHR23B Reveals Novel Proteasome-Associated Proteins†

(2009) Henrike C. Besche et al.   BIOCHEMISTRY

Autophagy Is Required to Maintain Muscle Mass

(2009) Eva Masiero et al.   Cell Metabolism

Age-related changes of cell death pathways in rat extraocular muscle

(2009) Colleen A. McMullen et al.   EXPERIMENTAL GERONTOLOGY

Increased muscle PGC-1  expression protects from sarcopenia and metabolic disease during aging

(2009) T. Wenz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Caloric restriction optimizes the proteasome pathway with aging in rat plantaris muscle: implications for sarcopenia

(2008) Russell T. Hepple et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Downregulation of muscle protein degradation in sepsis by eicosapentaenoic acid (EPA)

(2008) Jwan Khal et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Fast/Glycolytic Muscle Fiber Growth Reduces Fat Mass and Improves Metabolic Parameters in Obese Mice

(2008) Yasuhiro Izumiya et al.   Cell Metabolism

Skeletal muscle proteolysis in aging

(2008) Lydie Combaret et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

The initiation factor eIF3-f is a major target for Atrogin1/MAFbx function in skeletal muscle atrophy

(2008) Julie Lagirand-Cantaloube et al.   EMBO JOURNAL

Suppression of autophagy in skeletal muscle uncovers the accumulation of ubiquitinated proteins and their potential role in muscle damage in Pompe disease

(2008) N. Raben et al.   HUMAN MOLECULAR GENETICS

Sarcopenia: Its assessment, etiology, pathogenesis, consequences and future perspectives

(2008) Y. Rolland et al.   Journal of Nutrition Health & Aging

Human Sarcopenia Reveals an Increase in SOCS-3 and Myostatin and a Reduced Efficiency of Akt Phosphorylation

(2008) Bertrand Léger et al.   REJUVENATION RESEARCH