Spinal CCL2 Promotes Pain Sensitization by Rapid Enhancement of NMDA-Induced Currents Through the ERK-GluN2B Pathway in Mouse Lamina II Neurons

Decreased miR-325-5p Contributes to Visceral Hypersensitivity Through Post-transcriptional Upregulation of CCL2 in Rat Dorsal Root Ganglia

(2019) Rui Wu et al.   Neuroscience Bulletin

Astrocytes in chronic pain and itch

(2019) Ru-Rong Ji et al.   NATURE REVIEWS NEUROSCIENCE

Chemokine Receptor CXCR3 in the Spinal Cord Contributes to Chronic Itch in Mice

(2017) Peng-Bo Jing et al.   Neuroscience Bulletin

Spinal CCL2 Promotes Central Sensitization, Long-Term Potentiation, and Inflammatory Pain via CCR2: Further Insights into Molecular, Synaptic, and Cellular Mechanisms

(2017) Rou-Gang Xie et al.   Neuroscience Bulletin

Pain regulation by non-neuronal cells and inflammation

(2016) R.-R. Ji et al.   SCIENCE

β-arrestin-2 regulates NMDA receptor function in spinal lamina II neurons and duration of persistent pain

(2016) Gang Chen et al.   Nature Communications

TLR signaling adaptor protein MyD88 in primary sensory neurons contributes to persistent inflammatory and neuropathic pain and neuroinflammation

(2016) Xing-Jun Liu et al.   Scientific Reports

Identification of Spinal Circuits Transmitting and Gating Mechanical Pain

(2014) Bo Duan et al.   CELL

Chemokine CXCL1 enhances inflammatory pain and increases NMDA receptor activity and COX-2 expression in spinal cord neurons via activation of CXCR2

(2014) De-Li Cao et al.   EXPERIMENTAL NEUROLOGY

Emerging targets in neuroinflammation-driven chronic pain

(2014) Ru-Rong Ji et al.   NATURE REVIEWS DRUG DISCOVERY

Neurogenic neuroinflammation: inflammatory CNS reactions in response to neuronal activity

(2013) Dimitris N. Xanthos et al.   NATURE REVIEWS NEUROSCIENCE

Effect of NMDA NR2B antagonist on neuropathic pain in two spinal cord injury models

(2012) Youngkyung Kim et al.   PAIN

Chemokines and cytokines in neuroinflammation leading to neuropathic pain

(2011) Norikazu Kiguchi et al.   CURRENT OPINION IN PHARMACOLOGY

Resolvin D2 Is a Potent Endogenous Inhibitor for Transient Receptor Potential Subtype V1/A1, Inflammatory Pain, and Spinal Cord Synaptic Plasticity in Mice: Distinct Roles of Resolvin D1, D2, and E1

(2011) C.-K. Park et al.   JOURNAL OF NEUROSCIENCE

Long-Term Potentiation in Spinal Nociceptive Pathways as a Novel Target for Pain Therapy

(2011) Ruth Ruscheweyh et al.   Molecular Pain

cAMP-dependent protein kinase activated Fyn in spinal dorsal horn to regulate NMDA receptor function during inflammatory pain

(2010) Hong-Bin Yang et al.   JOURNAL OF NEUROCHEMISTRY

Nociceptor sensitization in pain pathogenesis

(2010) Michael S Gold et al.   NATURE MEDICINE

Neuronal circuitry for pain processing in the dorsal horn

(2010) Andrew J. Todd   NATURE REVIEWS NEUROSCIENCE

Chemokines, neuronal–glial interactions, and central processing of neuropathic pain

(2010) Yong-Jing Gao et al.   PHARMACOLOGY & THERAPEUTICS

Cellular and Molecular Mechanisms of Pain

(2009) Allan I. Basbaum et al.   CELL

JNK-Induced MCP-1 Production in Spinal Cord Astrocytes Contributes to Central Sensitization and Neuropathic Pain

(2009) Y.-J. Gao et al.   JOURNAL OF NEUROSCIENCE

Peripheral NMDA receptors revisited – Hope floats

(2009) Susan M. Carlton   PAIN

Chemokines and pain mechanisms

(2008) Catherine Abbadie et al.   BRAIN RESEARCH REVIEWS

AMPA and NMDA glutamate receptors are found in both peptidergic and non-peptidergic primary afferent neurons in the rat

(2008) Helen Willcockson et al.   CELL AND TISSUE RESEARCH

CCL2 is a key mediator of microglia activation in neuropathic pain states

(2008) Michael A. Thacker et al.   EUROPEAN JOURNAL OF PAIN

Increase of MCP-1 (CCL2) in myelin mutant Schwann cells is mediated by MEK-ERK signaling pathway

(2008) Stefan Fischer et al.   GLIA

Spinal CCL2 pronociceptive action is no longer effective in CCR2 receptor antagonist-treated rats

(2008) Marc-Andr Dansereau et al.   JOURNAL OF NEUROCHEMISTRY

Chemokine Action in the Nervous System

(2008) R. J. Miller et al.   JOURNAL OF NEUROSCIENCE

Force-Dependent Development of Neuropathic Central Pain and Time-Related CCL2/CCR2 Expression after Graded Spinal Cord Contusion Injuries of the Rat

(2008) Friederike Knerlich-Lukoschus et al.   JOURNAL OF NEUROTRAUMA