Long-Lived Skin-Resident Memory T Cells Contribute to Concomitant Immunity in Cutaneous Leishmaniasis

CD4+ resident memory T cells dominate immunosurveillance and orchestrate local recall responses

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CD4+ T Cell-Mediated Immunity against the Phagosomal Pathogen Leishmania: Implications for Vaccination

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Tissue-Specific Control of Tissue-Resident Memory T Cells

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Mannose receptor high, M2 dermal macrophages mediate nonhealingLeishmania majorinfection in a Th1 immune environment

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Cutting Edge: Tissue-Resident Memory T Cells Generated by Multiple Immunizations or Localized Deposition Provide Enhanced Immunity

(2017) Brooke Davies et al.   JOURNAL OF IMMUNOLOGY

Continual renewal and replication of persistentLeishmania majorparasites in concomitantly immune hosts

(2017) Michael A. Mandell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Persistent RNA virus infections: do PAMPS drive chronic disease?

(2017) Mary K McCarthy et al.   Current Opinion in Virology

Within host RNA virus persistence: mechanisms and consequences

(2017) Richard E Randall et al.   Current Opinion in Virology

A third generation vaccine for human visceral leishmaniasis and post kala azar dermal leishmaniasis: First-in-human trial of ChAd63-KH

(2017) Mohamed Osman et al.   PLoS Neglected Tropical Diseases

Skin-resident CD4+ T cells protect against Leishmania major by recruiting and activating inflammatory monocytes

(2017) Nelson D. Glennie et al.   PLoS Pathogens

Divergent roles for Ly6C+CCR2+CX3CR1+ inflammatory monocytes during primary or secondary infection of the skin with the intra-phagosomal pathogen Leishmania major

(2017) Audrey Romano et al.   PLoS Pathogens

CD8+ T cell cytotoxicity mediates pathology in the skin by inflammasome activation and IL-1β production

(2017) Fernanda O. Novais et al.   PLoS Pathogens

A defined subunit vaccine that protects against vector-borne visceral leishmaniasis

(2017) Malcolm S. Duthie et al.   npj Vaccines

Long-Term Immunity to Trypanosoma cruzi in the Absence of Immunodominanttrans-Sialidase-Specific CD8+T Cells

(2016) Charles S. Rosenberg et al.   INFECTION AND IMMUNITY

Hobit and Blimp1 instruct a universal transcriptional program of tissue residency in lymphocytes

(2016) L. K. Mackay et al.   SCIENCE

Concomitant Immunity Induced by Persistent Leishmania major Does Not Preclude Secondary Re-Infection: Implications for Genetic Exchange, Diversity and Vaccination

(2016) Michael A. Mandell et al.   PLoS Neglected Tropical Diseases

Skin-resident memory CD4+T cells enhance protection againstLeishmania majorinfection

(2015) Nelson D. Glennie et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Production of IL-10 by CD4+ regulatory T cells during the resolution of infection promotes the maturation of memory CD8+ T cells

(2015) Brian J Laidlaw et al.   NATURE IMMUNOLOGY

The emerging role of resident memory T cells in protective immunity and inflammatory disease

(2015) Chang Ook Park et al.   NATURE MEDICINE

Identification of broadly conserved cross-species protective Leishmania antigen and its responding CD4 + T cells

(2015) Zhirong Mou et al.   Science Translational Medicine

Resident memory T cells in human health and disease

(2015) R. A. Clark   Science Translational Medicine

Tissue-Resident Memory T Cells

(2014) Jason M. Schenkel et al.   IMMUNITY

The Central Memory CD4+ T Cell Population Generated during Leishmania major Infection Requires IL-12 to Produce IFN- 

(2014) N. Pakpour et al.   JOURNAL OF IMMUNOLOGY

Chronic Parasitic Infection Maintains High Frequencies of Short-Lived Ly6C+CD4+ Effector T Cells That Are Required for Protection against Re-infection

(2014) Nathan C. Peters et al.   PLoS Pathogens

MHC Class II Restricted Innate-Like Double Negative T Cells Contribute to Optimal Primary and Secondary Immunity to Leishmania major

(2014) Zhirong Mou et al.   PLoS Pathogens

Cytotoxic T Cells Mediate Pathology and Metastasis in Cutaneous Leishmaniasis

(2013) Fernanda O. Novais et al.   PLoS Pathogens

Skin infection generates non-migratory memory CD8+ TRM cells providing global skin immunity

(2012) Xiaodong Jiang et al.   NATURE

Long-lived epithelial immunity by tissue-resident memory T (TRM) cells in the absence of persisting local antigen presentation

(2012) L. K. Mackay et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An Interleukin-21- Interleukin-10-STAT3 Pathway Is Critical for Functional Maturation of Memory CD8+ T Cells

(2011) Weiguo Cui et al.   IMMUNITY

Platelet activation attracts a subpopulation of effector monocytes to sites ofLeishmania majorinfection

(2011) Ricardo Goncalves et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cutting Edge: Tissue-Retentive Lung Memory CD4 T Cells Mediate Optimal Protection to Respiratory Virus Infection

(2011) J. R. Teijaro et al.   JOURNAL OF IMMUNOLOGY

In brief

(2011)   NATURE REVIEWS MOLECULAR CELL BIOLOGY

From Vaccines to Memory and Back

(2010) Federica Sallusto et al.   IMMUNITY

Dynamic T cell migration program provides resident memory within intestinal epithelium

(2010) David Masopust et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The Early Generation of a Heterogeneous CD4+ T Cell Response to Leishmania major

(2010) S. L. Colpitts et al.   JOURNAL OF IMMUNOLOGY

IL-7 Receptor Expression Provides the Potential for Long-Term Survival of Both CD62Lhigh Central Memory T Cells and Th1 Effector Cells during Leishmania major Infection

(2009) S. L. Colpitts et al.   JOURNAL OF IMMUNOLOGY

Drug-induced cure drives conversion to a stable and protective CD8+ T central memory response in chronic Chagas disease

(2008) Juan M Bustamante et al.   NATURE MEDICINE

In Vivo Imaging Reveals an Essential Role for Neutrophils in Leishmaniasis Transmitted by Sand Flies

(2008) N. C. Peters et al.   SCIENCE