Splitsville: structural and functional insights into the dynamic bacterial Z ring

In Situ Cryo-Electron Tomography: A Post-Reductionist Approach to Structural Biology

(2016) Shoh Asano et al.   JOURNAL OF MOLECULAR BIOLOGY

Biological Insights from a Simulation Model of the Critical FtsZ Accumulation Required for Prokaryotic Cell Division

(2015) Claire E. Dow et al.   BIOCHEMISTRY

Bacterial Actin and Tubulin Homologs in Cell Growth and Division

(2015) Kimberly K. Busiek et al.   CURRENT BIOLOGY

Guiding divisome assembly and controlling its activity

(2015) Mary-Jane Tsang et al.   CURRENT OPINION IN MICROBIOLOGY

A NAD-dependent glutamate dehydrogenase coordinates metabolism with cell division in Caulobacter crescentus

(2015) F. Beaufay et al.   EMBO JOURNAL

The Soluble Periplasmic Domains ofEscherichia coliCell Division Proteins FtsQ/FtsB/FtsL Form a Trimeric Complex with Submicromolar Affinity

(2015) Marjolein Glas et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Evidence That Bacteriophage λ Kil Peptide Inhibits Bacterial Cell Division by Disrupting FtsZ Protofilaments and Sequestering Protein Subunits

(2015) Víctor M. Hernández-Rocamora et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Essential protein SepF of mycobacteria interacts with FtsZ and MurG to regulate cell growth and division

(2015) Shamba Gupta et al.   MICROBIOLOGY-SGM

Divisome-dependent subcellular localization of cell-cell joining protein SepJ in the filamentous cyanobacteriumAnabaena

(2015) Félix Ramos-León et al.   MOLECULAR MICROBIOLOGY

Phosphorylation of the cell division protein GpsB regulates PrkC kinase activity through a negative feedback loop inBacillus subtilis

(2015) Frédérique Pompeo et al.   MOLECULAR MICROBIOLOGY

A mutation inEscherichia coli ftsZbypasses the requirement for the essential division genezipAand confers resistance to FtsZ assembly inhibitors by stabilizing protofilament bundling

(2015) Daniel P. Haeusser et al.   MOLECULAR MICROBIOLOGY

A role for the FtsQLB complex in cytokinetic ring activation revealed by anftsLallele that accelerates division

(2015) Mary-Jane Tsang et al.   MOLECULAR MICROBIOLOGY

Last but not least: new insights into how FtsN triggers constriction duringEscherichia colicell division

(2015) David S. Weiss   MOLECULAR MICROBIOLOGY

The bypass of ZipA by overexpression of FtsN requires a previously unknown conserved FtsN motif essential for FtsA-FtsN interaction supporting a model in which FtsA monomers recruit late cell division proteins to the Z ring

(2015) Sebastien Pichoff et al.   MOLECULAR MICROBIOLOGY

Roles for both FtsA and the FtsBLQ subcomplex in FtsN-stimulated cell constriction inEscherichia coli

(2015) Bing Liu et al.   MOLECULAR MICROBIOLOGY

The essential role of SepF in mycobacterial division

(2015) Susanne Gola et al.   MOLECULAR MICROBIOLOGY

The bacterial divisome: ready for its close-up

(2015) Veronica W. Rowlett et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

FtsZ filament capping by MciZ, a developmental regulator of bacterial division

(2015) Alexandre W. Bisson-Filho et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bacterial SPOR domains are recruited to septal peptidoglycan by binding to glycan strands that lack stem peptides

(2015) Atsushi Yahashiri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Remodeling of the Z-Ring Nanostructure during the Streptococcus pneumoniae Cell Cycle Revealed by Photoactivated Localization Microscopy

(2015) Maxime Jacq et al.   mBio

The bacterial tubulin FtsZ requires its intrinsically disordered linker to direct robust cell wall construction

(2015) Kousik Sundararajan et al.   Nature Communications

A Multi-layered Protein Network Stabilizes the Escherichia coli FtsZ-ring and Modulates Constriction Dynamics

(2015) Jackson Buss et al.   PLoS Genetics

Coordination of peptidoglycan synthesis and outer membrane constriction during Escherichia coli cell division

(2015) Andrew N Gray et al.   eLife

The Min system and other nucleoid-independent regulators of Z ring positioning

(2015) Veronica W. Rowlett et al.   Frontiers in Microbiology

Dr-FtsA, an Actin Homologue in Deinococcus radiodurans Differentially Affects Dr-FtsZ and Ec-FtsZ Functions In Vitro

(2015) Kruti Modi et al.   PLoS One

Cytoplasmic Domain of MscS Interacts with Cell Division Protein FtsZ: A Possible Non-Channel Function of the Mechanosensitive Channel in Escherichia Coli

(2015) Piotr Koprowski et al.   PLoS One

Effective GTP-Replacing FtsZ Inhibitors and Antibacterial Mechanism of Action

(2014) Marta Artola et al.   ACS Chemical Biology

Unveiling the Inner Workings of Live Bacteria Using Super-Resolution Microscopy

(2014) Hannah H. Tuson et al.   ANALYTICAL CHEMISTRY

Drug discovery targeting cell division proteins, microtubules and FtsZ

(2014) Iwao Ojima et al.   BIOORGANIC & MEDICINAL CHEMISTRY

3D-SIM Super-resolution of FtsZ and Its Membrane Tethers in Escherichia coli Cells

(2014) Veronica Wells Rowlett et al.   BIOPHYSICAL JOURNAL

Crystal structure of FtsA fromStaphylococcus aureus

(2014) Junso Fujita et al.   FEBS LETTERS

Asymmetric Constriction of Dividing Escherichia coli Cells Induced by Expression of a Fusion between Two Min Proteins

(2014) V. W. Rowlett et al.   JOURNAL OF BACTERIOLOGY

Crystal Structure and Site-directed Mutational Analysis Reveals Key Residues Involved inEscherichia coliZapA Function

(2014) Elyse J. Roach et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A thermosensitive defect in the ATP binding pocket of FtsA can be suppressed by allosteric changes in the dimer interface

(2014) Jennifer R. Herricks et al.   MOLECULAR MICROBIOLOGY

Disassembly of the divisome inEscherichia coli: evidence that FtsZ dissociates before compartmentalization

(2014) Bill Söderström et al.   MOLECULAR MICROBIOLOGY

The bacterial septal ring protein RlpA is a lytic transglycosylase that contributes to rod shape and daughter cell separation inPseudomonas aeruginosa

(2014) Matthew A. Jorgenson et al.   MOLECULAR MICROBIOLOGY

Staphylococcus aureus DivIB is a peptidoglycan-binding protein that is required for a morphological checkpoint in cell division

(2014) Amy L. Bottomley et al.   MOLECULAR MICROBIOLOGY

Oligomerization of FtsZ converts the FtsZ tail motif (conserved carboxy-terminal peptide) into a multivalent ligand with high avidity for partners ZipA and SlmA

(2014) Shishen Du et al.   MOLECULAR MICROBIOLOGY

A role for FtsA in SPOR-independent localization of the essentialEscherichia colicell division protein FtsN

(2014) Kimberly K. Busiek et al.   MOLECULAR MICROBIOLOGY

ClpXP and ClpAP proteolytic activity on divisome substrates is differentially regulated following theCaulobacterasymmetric cell division

(2014) Brandon Williams et al.   MOLECULAR MICROBIOLOGY

Pbp2x localizes separately from Pbp2b and other peptidoglycan synthesis proteins during later stages of cell division ofStreptococcus pneumoniae D39

(2014) Ho-Ching T. Tsui et al.   MOLECULAR MICROBIOLOGY

MapZ marks the division sites and positions FtsZ rings in Streptococcus pneumoniae

(2014) Aurore Fleurie et al.   NATURE

How sisters grow apart: mycobacterial growth and division

(2014) Karen J. Kieser et al.   NATURE REVIEWS MICROBIOLOGY

Functional Domain Analysis of the Cell Division Inhibitor EzrA

(2014) Adrian D. Land et al.   PLoS One

High throughput 3D super-resolution microscopy reveals Caulobacter crescentus in vivo Z-ring organization

(2014) S. J. Holden et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MurJ is the flippase of lipid-linked precursors for peptidoglycan biogenesis

(2014) L.-T. Sham et al.   SCIENCE

Role of the FtsA C Terminus as a Switch for Polymerization and Membrane Association

(2014) Marcin Krupka et al.   mBio

LocZ Is a New Cell Division Protein Involved in Proper Septum Placement in Streptococcus pneumoniae

(2014) N. Holeckova et al.   mBio

ZapE Is a Novel Cell Division Protein Interacting with FtsZ and Modulating the Z-Ring Dynamics

(2014) B. S. Marteyn et al.   mBio

Coordinating Bacterial Cell Division with Nutrient Availability: a Role for Glycolysis

(2014) L. G. Monahan et al.   mBio

Size-independent symmetric division in extraordinarily long cells

(2014) Nika Pende et al.   Nature Communications

Structure and function of a spectrin-like regulator of bacterial cytokinesis

(2014) Robert M. Cleverley et al.   Nature Communications

A DNA Damage-Induced, SOS-Independent Checkpoint Regulates Cell Division in Caulobacter crescentus

(2014) Joshua W. Modell et al.   PLOS BIOLOGY

The Kil Peptide of Bacteriophage λ Blocks Escherichia coli Cytokinesis via ZipA-Dependent Inhibition of FtsZ Assembly

(2014) Daniel P. Haeusser et al.   PLoS Genetics

Interplay of the Serine/Threonine-Kinase StkP and the Paralogs DivIVA and GpsB in Pneumococcal Cell Elongation and Division

(2014) Aurore Fleurie et al.   PLoS Genetics

General principles for the formation and proliferation of a wall-free (L-form) state in bacteria

(2014) Romain Mercier et al.   eLife

Architecture of the ring formed by the tubulin homologue FtsZ in bacterial cell division

(2014) Piotr Szwedziak et al.   eLife

Division site positioning in bacteria: one size does not fit all

(2014) Leigh G. Monahan et al.   Frontiers in Microbiology

Cell division in Corynebacterineae

(2014) Catriona Donovan et al.   Frontiers in Microbiology

The N-terminal domain of EzrA binds to the C terminus of FtsZ to inhibit Staphylococcus aureus FtsZ polymerization

(2013) Sang Hyeon Son et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Transmembrane Domains of the Bacterial Cell Division Proteins FtsB and FtsL Form a Stable High-Order Oligomer

(2013) Ambalika S. Khadria et al.   BIOCHEMISTRY

Spectrins: A structural platform for stabilization and activation of membrane channels, receptors and transporters

(2013) Beata Machnicka et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Organization of FtsZ Filaments in the Bacterial Division Ring Measured from Polarized Fluorescence Microscopy

(2013) Fangwei Si et al.   BIOPHYSICAL JOURNAL

Erratum to “Form and function of the bacterial cytokinetic ring” [Curr. Opin. Cell Biol. 26 (2014) 19–27]

(2013) Elizabeth L Meier et al.   CURRENT OPINION IN CELL BIOLOGY

Bacterial cell division as a target for new antibiotics

(2013) Peter Sass et al.   CURRENT OPINION IN MICROBIOLOGY

Essential and non-essential interactions in interactome networks: theEscherichia colidivision proteins FtsQ-FtsN interaction

(2013) L. Grenga et al.   ENVIRONMENTAL MICROBIOLOGY

Three-dimensional structure of the Z-ring as a random network of FtsZ filaments

(2013) Oreste Piro et al.   ENVIRONMENTAL MICROBIOLOGY

FtsZ Ring Stability: of Bundles, Tubules, Crosslinks, and Curves

(2013) K.-H. Huang et al.   JOURNAL OF BACTERIOLOGY

The Conserved DNA-Binding Protein WhiA Is Involved in Cell Division in Bacillus subtilis

(2013) K. Surdova et al.   JOURNAL OF BACTERIOLOGY

Fine-mapping the Contact Sites of theEscherichia coliCell Division Proteins FtsB and FtsL on the FtsQ Protein

(2013) H. Bart van den Berg van Saparoea et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bacterial Division Proteins FtsZ and ZipA Induce Vesicle Shrinkage and Cell Membrane Invagination

(2013) Elisa J. Cabré et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

In the Beginning,Escherichia coliAssembled the Proto-ring: An Initial Phase of Division

(2013) Ana Isabel Rico et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

yneA mRNA instability is involved in temporary inhibition of cell division during the SOS response of Bacillus megaterium

(2013) M. Buchholz et al.   MICROBIOLOGY-SGM

An essential enzyme for phospholipid synthesis associates with theBacillus subtilisdivisome

(2013) Hiraku Takada et al.   MOLECULAR MICROBIOLOGY

Requirement of essential Pbp2x and GpsB for septal ring closure inStreptococcus pneumoniae D39

(2013) Adrian D. Land et al.   MOLECULAR MICROBIOLOGY

The C-terminal linker ofEscherichia coli FtsZ functions as an intrinsically disordered peptide

(2013) Kiani A. J. Arkus Gardner et al.   MOLECULAR MICROBIOLOGY

A flexible C-terminal linker is required for proper FtsZ assemblyin vitroand cytokinetic ring formationin vivo

(2013) P. J. Buske et al.   MOLECULAR MICROBIOLOGY

In vivoorganization of the FtsZ-ring by ZapA and ZapB revealed by quantitative super-resolution microscopy

(2013) Jackson Buss et al.   MOLECULAR MICROBIOLOGY

The bacterial cell division proteins FtsA and FtsZ self-organize into dynamic cytoskeletal patterns

(2013) Martin Loose et al.   NATURE CELL BIOLOGY

How to get (a)round: mechanisms controlling growth and division of coccoid bacteria

(2013) Mariana G. Pinho et al.   NATURE REVIEWS MICROBIOLOGY

Phage  29 protein p1 promotes replication by associating with the FtsZ ring of the divisome in Bacillus subtilis

(2013) D. Ballesteros-Plaza et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gene product 0.4 increases bacteriophage T7 competitiveness by inhibiting host cell division

(2013) R. Kiro et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural and genetic analyses reveal the protein SepF as a new membrane anchor for the Z ring

(2013) R. Duman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Liposome division by a simple bacterial division machinery

(2013) M. Osawa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

FtsZ Protofilaments Use a Hinge-Opening Mechanism for Constrictive Force Generation

(2013) Y. Li et al.   SCIENCE

A Moonlighting Enzyme Links Escherichia coli Cell Size with Central Metabolism

(2013) Norbert S. Hill et al.   PLoS Genetics

The physiology of bacterial cell division

(2012) Alexander J. F. Egan et al.   Annals of the New York Academy of Sciences

The Escherichia coli Cell Division Protein ZipA Forms Homodimers Prior to Association with FtsZ

(2012) Karl Skoog et al.   BIOCHEMISTRY

SulA Inhibits Assembly of FtsZ by a Simple Sequestration Mechanism

(2012) Yaodong Chen et al.   BIOCHEMISTRY

Growth in width and FtsZ ring longitudinal positioning in a gammaproteobacterial symbiont

(2012) Nikolaus Leisch et al.   CURRENT BIOLOGY

FtsA forms actin-like protofilaments

(2012) Piotr Szwedziak et al.   EMBO JOURNAL

Identification of ZapD as a Cell Division Factor That Promotes the Assembly of FtsZ in Escherichia coli

(2012) J. Durand-Heredia et al.   JOURNAL OF BACTERIOLOGY

ZipA Is Required for FtsZ-Dependent Preseptal Peptidoglycan Synthesis prior to Invagination during Cell Division

(2012) L.-P. Potluri et al.   JOURNAL OF BACTERIOLOGY

The Early Divisome Protein FtsA Interacts Directly through Its 1c Subdomain with the Cytoplasmic Domain of the Late Divisome Protein FtsN

(2012) K. K. Busiek et al.   JOURNAL OF BACTERIOLOGY

Dynamic Interaction of theEscherichia coliCell Division ZipA and FtsZ Proteins Evidenced in Nanodiscs

(2012) Víctor M. Hernández-Rocamora et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Extreme C Terminus of Bacterial Cytoskeletal Protein FtsZ Plays Fundamental Role in Assembly Independent of Modulatory Proteins

(2012) Paul J. Buske et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PomZ, a ParA-like protein, regulates Z-ring formation and cell division inMyxococcus xanthus

(2012) Anke Treuner-Lange et al.   MOLECULAR MICROBIOLOGY

Changes in the oligomerization potential of the division inhibitor UgtP co-ordinateBacillus subtiliscell size with nutrient availability

(2012) An-Chun Chien et al.   MOLECULAR MICROBIOLOGY

Bacillus subtilis SepF Binds to the C-Terminus of FtsZ

(2012) Ewa Król et al.   PLoS One

Polar growth in the Alphaproteobacterial order Rhizobiales

(2012) P. J. B. Brown et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

3D-SIM Super Resolution Microscopy Reveals a Bead-Like Arrangement for FtsZ and the Division Machinery: Implications for Triggering Cytokinesis

(2012) Michael P. Strauss et al.   PLOS BIOLOGY

Large ring polymers align FtsZ polymers for normal septum formation

(2011) Muhammet E Gündoğdu et al.   EMBO JOURNAL

Identification of FtsW as a transporter of lipid-linked cell wall precursors across the membrane

(2011) Tamimount Mohammadi et al.   EMBO JOURNAL

A DNA damage checkpoint in Caulobacter crescentus inhibits cell division through a direct interaction with FtsW

(2011) J. W. Modell et al.   GENES & DEVELOPMENT

Positive control of cell division: FtsZ is recruited by SsgB during sporulation of Streptomyces

(2011) J. Willemse et al.   GENES & DEVELOPMENT

The Interplay of ClpXP with the Cell Division Machinery in Escherichia coli

(2011) J. L. Camberg et al.   JOURNAL OF BACTERIOLOGY

Identification of Escherichia coli ZapC (YcbW) as a Component of the Division Apparatus That Binds and Bundles FtsZ Polymers

(2011) C. A. Hale et al.   JOURNAL OF BACTERIOLOGY

Identification and Characterization of ZapC, a Stabilizer of the FtsZ Ring in Escherichia coli

(2011) J. M. Durand-Heredia et al.   JOURNAL OF BACTERIOLOGY

FtsA mutants impaired for self-interaction bypass ZipA suggesting a model in which FtsA's self-interaction competes with its ability to recruit downstream division proteins

(2011) Sebastien Pichoff et al.   MOLECULAR MICROBIOLOGY

Multiple essential roles for EzrA in cell division of Staphylococcus aureus

(2011) Victoria R. Steele et al.   MOLECULAR MICROBIOLOGY

Two Mechanosensitive Channel Homologs Influence Division Ring Placement inArabidopsisChloroplasts

(2011) Margaret E. Wilson et al.   PLANT CELL

An ATP-binding cassette transporter-like complex governs cell-wall hydrolysis at the bacterial cytokinetic ring

(2011) D. C. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Coupling Prokaryotic Cell Fate and Division Control with a Bifunctional and Oscillating Oxidoreductase Homolog

(2010) Sunish Kumar Radhakrishnan et al.   DEVELOPMENTAL CELL

YneA, an SOS-Induced Inhibitor of Cell Division in Bacillus subtilis, Is Regulated Posttranslationally and Requires the Transmembrane Region for Activity

(2010) A. H. Mo et al.   JOURNAL OF BACTERIOLOGY

E93R Substitution ofEscherichia coliFtsZ Induces Bundling of Protofilaments, Reduces GTPase Activity, and Impairs Bacterial Cytokinesis

(2010) Richa Jaiswal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Direct interactions of early and late assembling division proteins in Escherichia coli cells resolved by FRET

(2010) Svetlana Alexeeva et al.   MOLECULAR MICROBIOLOGY

FtsK - a bacterial cell division checkpoint?

(2010) Ian Grainge   MOLECULAR MICROBIOLOGY

Wnt Isoform-Specific Interactions with Coreceptor Specify Inhibition or Potentiation of Signaling by LRP6 Antibodies

(2010) Yan Gong et al.   PLoS One

Self-Enhanced Accumulation of FtsN at Division Sites and Roles for Other Proteins with a SPOR Domain (DamX, DedD, and RlpA) in Escherichia coli Cell Constriction

(2009) M. A. Gerding et al.   JOURNAL OF BACTERIOLOGY

Two-Step Assembly Dynamics of the Bacillus subtilis Divisome

(2009) P. Gamba et al.   JOURNAL OF BACTERIOLOGY

Adenine Nucleotide-dependent Regulation of Assembly of Bacterial Tubulin-like FtsZ by a Hypermorph of Bacterial Actin-like FtsA

(2009) Tushar K. Beuria et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The conserved C-terminal tail of FtsZ is required for the septal localization and division inhibitory activity of MinCC/MinD

(2009) Bang Shen et al.   MOLECULAR MICROBIOLOGY

Control of the cell elongation–division cycle by shuttling of PBP1 protein in Bacillus subtilis

(2008) Dennis Claessen et al.   MOLECULAR MICROBIOLOGY

Cell-division inhibitors: new insights for future antibiotics

(2008) Rowena L. Lock et al.   NATURE REVIEWS DRUG DISCOVERY

Reconstitution of Contractile FtsZ Rings in Liposomes

(2008) M. Osawa et al.   SCIENCE