Modeling better in vitro models for the prediction of nanoparticle toxicity: a review

Materials and Technologies to Combat Counterfeiting of Pharmaceuticals: Current and Future Problem Tackling

(2020) Heyang Zhang et al.   ADVANCED MATERIALS

Small ultra-red fluorescent protein nanoparticles as exogenous probes for noninvasive tumor imaging in vivo

(2020) Feifei An et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Complex cytotoxicity mechanism of bundles formed from self-organised 1-D anodic TiO2 nanotubes layers

(2020) Hana Michalkova et al.   JOURNAL OF HAZARDOUS MATERIALS

Multi-walled carbon nanotubes (MWCNTs) transformed THP-1 macrophages into foam cells: Impact of pulmonary surfactant component dipalmitoylphosphatidylcholine

(2020) Jinru Lin et al.   JOURNAL OF HAZARDOUS MATERIALS

Multi-walled carbon nanotubes decrease neuronal NO synthase in 3D brain organoids

(2020) Ying Jiang et al.   SCIENCE OF THE TOTAL ENVIRONMENT

In vitro detection of in vitro secondary mechanisms of genotoxicity induced by engineered nanomaterials

(2019) Stephen J. Evans et al.   Particle and Fibre Toxicology

MWCNT interactions with protein: surface-induced changes in protein adsorption and the impact of protein corona on cellular uptake and cytotoxicity

(2019) Ting Zhang et al.   International Journal of Nanomedicine

Pre-incubated with BSA-complexed free fatty acids alters ER stress/autophagic gene expression by carboxylated multi-walled carbon nanotube exposure in THP-1 macrophages

(2019) Qianyu Yang et al.   CHINESE CHEMICAL LETTERS

Progress and Prospects of Graphdiyne-Based Materials in Biomedical Applications

(2019) Jiaming Liu et al.   ADVANCED MATERIALS

Caenorhabditis elegans as a complete model organism for biosafety assessments of nanoparticles

(2019) Tianshu Wu et al.   CHEMOSPHERE

Cr(VI)/Pb2+ are responsible for PM2.5-induced cytotoxicity in A549 cells while pulmonary surfactant alleviates such toxicity

(2019) Jianbo Jia et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Cyanidin chloride modestly protects Caco-2 cells from ZnO nanoparticle exposure probably through the induction of autophagy

(2019) Leying Jiang et al.   FOOD AND CHEMICAL TOXICOLOGY

Individual brain organoids reproducibly form cell diversity of the human cerebral cortex

(2019) Silvia Velasco et al.   NATURE

Organoids-on-a-chip

(2019) Sunghee Estelle Park et al.   SCIENCE

Towards manufacturing of human organoids

(2019) Aswathi Ashok et al.   BIOTECHNOLOGY ADVANCES

Air pollution and cardiovascular disease: car sick

(2019) Mark R Miller et al.   CARDIOVASCULAR RESEARCH

Oral administration of hydroxylated-graphene quantum dots induces intestinal injury accompanying the loss of intestinal stem cells and proliferative progenitor cells

(2019) Lan Yu et al.   Nanotoxicology

Engineering of human brain organoids with a functional vascular-like system

(2019) Bilal Cakir et al.   NATURE METHODS

Two-dimensional hybrid nanomaterials derived from MXenes (Ti3C2Tx) as advanced energy storage and conversion applications

(2019) Sen Zhao et al.   CHINESE CHEMICAL LETTERS

Evaluation of in vitro toxicity of silica nanoparticles (NPs) to lung cells: Influence of cell types and pulmonary surfactant component DPPC

(2019) Jing Li et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Longitudinal follow-up of health effects among workers handling engineered nanomaterials: a panel study

(2019) Wei-Te Wu et al.   Environmental Health

Toxicological study of metal and metal oxide nanoparticles in zebrafish

(2019) Changcun Bai et al.   JOURNAL OF APPLIED TOXICOLOGY

Carbonization: A feasible route for reutilization of plastic wastes

(2019) Shuiliang Chen et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Pharmacological and toxicological aspects of carbon nanotubes (CNTs) to vascular system: A review

(2019) Yi Cao et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Ongoing inflammation enhances the toxicity of engineered nanomaterials: Application of an in vitro co-culture model of the healthy and inflamed intestine

(2019) Angela A.M. Kämpfer et al.   TOXICOLOGY IN VITRO

The interaction between nanoparticles-protein corona complex and cells and its toxic effect on cells

(2019) Na Liu et al.   CHEMOSPHERE

Computational Investigations of the Interaction between the Cell Membrane and Nanoparticles Coated with a Pulmonary Surfactant

(2018) Xuan Bai et al.   ACS Applied Materials & Interfaces

A review of cardiovascular toxicity of TiO2, ZnO and Ag nanoparticles (NPs)

(2018) Yi Cao et al.   BIOMETALS

Effects of cerium oxide nanoparticles on differentiated/undifferentiated human intestinal Caco-2 cells

(2018) Laura Vila et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Cytotoxicity, cytokine release and ER stress-autophagy gene expression in endothelial cells and alveolar-endothelial co-culture exposed to pristine and carboxylated multi-walled carbon nanotubes

(2018) Shiwei Chang et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

A guide to polarized airway epithelial models for studies of host-pathogen interactions

(2018) Shakir Hasan et al.   FEBS Journal

Comparative cytotoxicity and apoptotic pathways induced by nanosilver in human liver HepG2 and L02 cells

(2018) Y Xue et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Acute effects of multi-walled carbon nanotubes on primary bronchial epithelial cells from COPD patients

(2018) Seraina Beyeler et al.   Nanotoxicology

Cardiopulmonary effects induced by occupational exposure to titanium dioxide nanoparticles

(2018) Lin Zhao et al.   Nanotoxicology

Using primary organotypic mouse midbrain cultures to examine developmental neurotoxicity of silver nanoparticles across two genetic strains

(2018) Brittany A. Weldon et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Stimuli-responsive nanotherapeutics for precision drug delivery and cancer therapy

(2018) Yiting Qiao et al.   Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology

Internalization, cytotoxicity, oxidative stress and inflammation of multi-walled carbon nanotubes in human endothelial cells: influence of pre-incubation with bovine serum albumin

(2018) Jimin Long et al.   RSC Advances

Synthesis, functionalization, and nanomedical applications of functional magnetic nanoparticles

(2018) Zhou Chen et al.   CHINESE CHEMICAL LETTERS

Protein Corona Mediated Uptake and Cytotoxicity of Silver Nanoparticles in Mouse Embryonic Fibroblast

(2018) Marianna Barbalinardo et al.   Small

Air Pollution and Noncommunicable Diseases

(2018) Dean E. Schraufnagel et al.   CHEST

Protein Food Matrix–ZnO Nanoparticle Interactions Affect Protein Conformation, but May not Be Biological Responses

(2018) Song-Hwa Bae et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The impact of protein corona on the behavior and targeting capability of nanoparticle-based delivery system

(2018) Wei Xiao et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Nanopharmaceuticals and nanomedicines currently on the market: challenges and opportunities

(2018) Fatemeh Farjadian et al.   Nanomedicine

Toxicological characterization of ZnO nanoparticles in malignant and non-malignant cells

(2017) Helena Moratin et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Toxicity of ZnO nanoparticles (NPs) to A549 cells and A549 epithelium in vitro : Interactions with dipalmitoyl phosphatidylcholine (DPPC)

(2017) Tong He et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

The endoplasmic reticulum stress inducer thapsigargin enhances the toxicity of ZnO nanoparticles to macrophages and macrophage-endothelial co-culture

(2017) Gui Chen et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Formulation and characterization of biocompatible and stable I.V. itraconazole nanosuspensions stabilized by a new stabilizer polyethylene glycol-poly(β-Benzyl- l -aspartate) (PEG-PBLA)

(2017) Lanlan Zong et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

A review of endoplasmic reticulum (ER) stress and nanoparticle (NP) exposure

(2017) Yi Cao et al.   LIFE SCIENCES

Synthesis and evaluation of the cytotoxic and anti-proliferative properties of ZnO quantum dots against MCF-7 and MDA-MB-231 human breast cancer cells

(2017) Roshini A. et al.   Materials Science & Engineering C-Materials for Biological Applications

Quantum dot interactions and flow effects in angiogenic zebrafish ( Danio rerio ) vessels and human endothelial cells

(2017) Xiao-Yu Jiang et al.   Nanomedicine-Nanotechnology Biology and Medicine

Supported pulmonary surfactant bilayers on silica nanoparticles: formulation, stability and impact on lung epithelial cells

(2017) F. Mousseau et al.   Nanoscale

Impact of copper oxide nanomaterials on differentiated and undifferentiated Caco-2 intestinal epithelial cells; assessment of cytotoxicity, barrier integrity, cytokine production and nanomaterial penetration

(2017) Victor C. Ude et al.   Particle and Fibre Toxicology

The unrecognized occupational relevance of the interaction between engineered nanomaterials and the gastro-intestinal tract: a consensus paper from a multidisciplinary working group

(2017) Antonio Pietroiusti et al.   Particle and Fibre Toxicology

Architecture in 3D cell culture: An essential feature for in vitro toxicology

(2017) Sophie A. Lelièvre et al.   TOXICOLOGY IN VITRO

Insights on wood combustion generated proinflammatory ultrafine particles (UFP)

(2017) Emanuela Corsini et al.   TOXICOLOGY LETTERS

Disease Modeling in Stem Cell-Derived 3D Organoid Systems

(2017) Devanjali Dutta et al.   TRENDS IN MOLECULAR MEDICINE

2D MoS2 Nanostructures for Biomedical Applications

(2017) Teng Liu et al.   Advanced Healthcare Materials

Light scattering based analyses of the effects of bovine serum proteins on interactions of magnetite spherical particles with cells

(2017) Lingling Guo et al.   CHINESE CHEMICAL LETTERS

Zinc Oxide Flower-Like Nanostructures That Exhibit Enhanced Toxicology Effects in Cancer Cells

(2016) Iêda M. M. Paino et al.   ACS Applied Materials & Interfaces

Beyond PM2.5: The role of ultrafine particles on adverse health effects of air pollution

(2016) Rui Chen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Role of fluid shear stress in regulating VWF structure, function and related blood disorders

(2016) Shobhit Gogia et al.   BIORHEOLOGY

Pulmonary surfactant mitigates silver nanoparticle toxicity in human alveolar type-I-like epithelial cells

(2016) Sinbad Sweeney et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Consideration of interaction between nanoparticles and food components for the safety assessment of nanoparticles following oral exposure: A review

(2016) Yi Cao et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Comparison of the DNA damage response in BEAS-2B and A549 cells exposed to titanium dioxide nanoparticles

(2016) M. Biola-Clier et al.   MUTAGENESIS

Cell cycle dependent cellular uptake of zinc oxide nanoparticles in human epidermal cells

(2016) Pal Patel et al.   MUTAGENESIS

Protein corona modulation of hepatocyte uptake and molecular mechanisms of gold nanoparticle toxicity

(2016) Kyoungju Choi et al.   Nanotoxicology

Protein corona formation in bronchoalveolar fluid enhances diesel exhaust nanoparticle uptake and pro-inflammatory responses in macrophages

(2016) Catherine A. Shaw et al.   Nanotoxicology

Effect of pulmonary surfactant on the dissolution, stability and uptake of zinc oxide nanowires by human respiratory epithelial cells

(2016) Ioannis G. Theodorou et al.   Nanotoxicology

Tuning the inflammatory response to silver nanoparticles via quercetin in Caco-2 (co-)cultures as model of the human intestinal mucosa

(2016) Alina Martirosyan et al.   TOXICOLOGY LETTERS

Dynamic protein coronas revealed as a modulator of silver nanoparticle sulphidation in vitro

(2016) Teodora Miclăuş et al.   Nature Communications

Protein Corona Influences Cellular Uptake of Gold Nanoparticles by Phagocytic and Nonphagocytic Cells in a Size-Dependent Manner

(2015) Xiaju Cheng et al.   ACS Applied Materials & Interfaces

Impact of food components during in vitro digestion of silver nanoparticles on cellular uptake and cytotoxicity in intestinal cells

(2015) Dajana Lichtenstein et al.   BIOLOGICAL CHEMISTRY

Investigation on cobalt-oxide nanoparticles cyto-genotoxicity and inflammatory response in two types of respiratory cells

(2015) Delia Cavallo et al.   JOURNAL OF APPLIED TOXICOLOGY

Three dimensional spheroid cell culture for nanoparticle safety testing

(2015) Franziska Sambale et al.   JOURNAL OF BIOTECHNOLOGY

Evaluation of gold nanoparticles toxicity towards human endothelial cells under static and flow conditions

(2015) Caterina Fede et al.   MICROVASCULAR RESEARCH

The role of the cell cycle in the cellular uptake of folate-modified poly(l-amino acid) micelles in a cell population

(2015) Jihui Tang et al.   Nanoscale

Complementary analysis of the hard and soft protein corona: sample preparation critically effects corona composition

(2015) S. Winzen et al.   Nanoscale

Protein corona mitigates the cytotoxicity of graphene oxide by reducing its physical interaction with cell membrane

(2015) Guangxin Duan et al.   Nanoscale

Surfactant protein A (SP-A) inhibits agglomeration and macrophage uptake of toxic amine modified nanoparticles

(2015) Zofi McKenzie et al.   Nanotoxicology

A 3D co-culture of three human cell lines to model the inflamed intestinal mucosa for safety testing of nanomaterials

(2015) Julia Susewind et al.   Nanotoxicology

Cyto- and genotoxic effects of metallic nanoparticles in untransformed human fibroblast

(2015) Leonardo P. Franchi et al.   TOXICOLOGY IN VITRO

Pulmonary surfactant augments cytotoxicity of silica nanoparticles: Studies on an in vitro air–blood barrier model

(2015) Jennifer Y Kasper et al.   Beilstein Journal of Nanotechnology

Nanotechnology in the real world: Redeveloping the nanomaterial consumer products inventory

(2015) Marina E Vance et al.   Beilstein Journal of Nanotechnology

A Co-Culture System with an Organotypic Lung Slice and an Immortal Alveolar Macrophage Cell Line to Quantify Silica-Induced Inflammation

(2015) Falk Hofmann et al.   PLoS One

Role of oxidative stress in carbon nanotube-generated health effects

(2014) Peter Møller et al.   ARCHIVES OF TOXICOLOGY

Nanoparticle toxicity assessment using an in vitro 3-D kidney organoid culture model

(2014) Anna I. Astashkina et al.   BIOMATERIALS

Iron oxide nanoparticles mediated cytotoxicity via PI3K/AKT pathway: Role of quercetin

(2014) Abhijit Sarkar et al.   FOOD AND CHEMICAL TOXICOLOGY

Evaluation of cytotoxic, genotoxic and inflammatory response in human alveolar and bronchial epithelial cells exposed to titanium dioxide nanoparticles

(2014) Cinzia Lucia Ursini et al.   JOURNAL OF APPLIED TOXICOLOGY

A combined toxicity study of zinc oxide nanoparticles and vitamin C in food additives

(2014) Yanli Wang et al.   Nanoscale

Biomimicry 3D Gastrointestinal Spheroid Platform for the Assessment of Toxicity and Inflammatory Effects of Zinc Oxide Nanoparticles

(2014) Sing Ling Chia et al.   Small

Single Cell Array Based Assay for in Vitro Genotoxicity Study of Nanomaterials

(2013) Yong Qiao et al.   ANALYTICAL CHEMISTRY

Toxicity evaluation of engineered nanoparticles for medical applications using pulmonary epithelial cells

(2013) Rina Guadagnini et al.   Nanotoxicology

Inorganic nanoparticle biomolecular corona: formation, evolution and biological impact

(2012) Eudald Casals et al.   Nanomedicine

Surfactant protein D (SP-D) alters cellular uptake of particles and nanoparticles

(2012) Michaela Kendall et al.   Nanotoxicology

Influence of simulated gastrointestinal conditions on particle-induced cytotoxicity and interleukin-8 regulation in differentiated and undifferentiated Caco-2 cells

(2012) Kirsten Gerloff et al.   Nanotoxicology

On-Chip Evaluation of Shear Stress Effect on Cytotoxicity of Mesoporous Silica Nanoparticles

(2011) Donghyuk Kim et al.   ANALYTICAL CHEMISTRY

Hazard identification of particulate matter on vasomotor dysfunction and progression of atherosclerosis

(2011) Peter Møller et al.   CRITICAL REVIEWS IN TOXICOLOGY

Rapid dissolution of ZnO nanocrystals in acidic cancer microenvironment leading to preferential apoptosis

(2011) Abhilash Sasidharan et al.   Nanoscale

Role of cell cycle on the cellular uptake and dilution of nanoparticles in a cell population

(2011) Jong Ah Kim et al.   Nature Nanotechnology

Inflammatory and cytotoxic responses of an alveolar-capillary coculture model to silica nanoparticles: Comparison with conventional monocultures

(2011) Jennifer Kasper et al.   Particle and Fibre Toxicology

SWCNT suppress inflammatory mediator responses in human lung epithelium in vitro

(2008) Eva Herzog et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY