Biomimicry 3D Gastrointestinal Spheroid Platform for the Assessment of Toxicity and Inflammatory Effects of Zinc Oxide Nanoparticles

Nano-hydroxyapatite and Nano-titanium Dioxide Exhibit Different Subcellular Distribution and Apoptotic Profile in Human Oral Epithelium

(2014) Chor Yong Tay et al.   ACS Applied Materials & Interfaces

Back to Basics: Exploiting the Innate Physico-chemical Characteristics of Nanomaterials for Biomedical Applications

(2014) Chor Yong Tay et al.   ADVANCED FUNCTIONAL MATERIALS

The influence of lysosomal stability of silver nanomaterials on their toxicity to human cells

(2014) Magdiel Inggrid Setyawati et al.   BIOMATERIALS

Presentation matters: Identity of gold nanocluster capping agent governs intracellular uptake and cell metabolism

(2014) Chor Yong Tay et al.   Nano Research

Exploiting cancer's antioxidative weakness through p53 with nanotoxicology

(2014) Magdiel Inggrid Setyawati et al.   Nanomedicine

Targeting tumour-supportive cellular machineries in anticancer drug development

(2014) Matthias Dobbelstein et al.   NATURE REVIEWS DRUG DISCOVERY

Estimating the effective density of engineered nanomaterials for in vitro dosimetry

(2014) Glen DeLoid et al.   Nature Communications

Amphiphilic Polymeric Nanocarriers with Luminescent Gold Nanoclusters for Concurrent Bioimaging and Controlled Drug Release

(2013) Dongyun Chen et al.   ADVANCED FUNCTIONAL MATERIALS

A bioengineered 3D ovarian cancer model for the assessment of peptidase–mediated enhancement of spheroid growth and intraperitoneal spread

(2013) Daniela Loessner et al.   BIOMATERIALS

Effect of zinc oxide nanomaterials-induced oxidative stress on the p53 pathway

(2013) Magdiel I. Setyawati et al.   BIOMATERIALS

3D pancreatic carcinoma spheroids induce a matrix-rich, chemoresistant phenotype offering a better model for drug testing

(2013) Paola Longati et al.   BMC CANCER

Engineering ultrasmall water-soluble gold and silver nanoclusters for biomedical applications

(2013) Zhentao Luo et al.   CHEMICAL COMMUNICATIONS

Kinetically Controlled Crystallization for Synthesis of Monodispersed Coordination Polymer Nanocubes and Their Self-Assembly to Periodic Arrangements

(2013) Ming Hu et al.   CHEMISTRY-A EUROPEAN JOURNAL

Nanoparticles Strengthen Intracellular Tension and Retard Cellular Migration

(2013) Chor Yong Tay et al.   NANO LETTERS

Reciprocal Response of Human Oral Epithelial Cells to Internalized Silica Nanoparticles

(2013) Chor Yong Tay et al.   PARTICLE & PARTICLE SYSTEMS CHARACTERIZATION

Predictive value of in vitro assays depends on the mechanism of toxicity of metal oxide nanoparticles

(2013) Wan-Seob Cho et al.   Particle and Fibre Toxicology

Comparison of Nanotube-Protein Corona Composition in Cell Culture Media

(2013) Jonathan H. Shannahan et al.   Small

Fibroblasts Cultured on Nanowires Exhibit Low Motility, Impaired Cell Division, and DNA Damage

(2013) Henrik Persson et al.   Small

Titanium dioxide nanomaterials cause endothelial cell leakiness by disrupting the homophilic interaction of VE–cadherin

(2013) M.I. Setyawati et al.   Nature Communications

Eyes on 3D-Current 3D Biomimetic Disease Concept Models and Potential Applications in Age-Related Macular Degeneration

(2013) Beatrix Feigl et al.   Advanced Healthcare Materials

Autophagy, Apoptosis, Mitoptosis and Necrosis: Interdependence Between Those Pathways and Effects on Cancer

(2012) Wiem Chaabane et al.   ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS

Cancer cell spheroids as a model to evaluate chemotherapy protocols

(2012) Federico Perche et al.   CANCER BIOLOGY & THERAPY

Three-dimensional tissue cultures: current trends and beyond

(2012) Henry Page et al.   CELL AND TISSUE RESEARCH

Inflammasomes in health and disease

(2012) Till Strowig et al.   NATURE

Interfacing Engineered Nanoparticles with Biological Systems: Anticipating Adverse Nano-Bio Interactions

(2012) Beatriz Pelaz et al.   Small

In vivo–in vitro comparison of acute respiratory tract toxicity using human 3D airway epithelial models and human A549 and murine 3T3 monolayer cell systems

(2012) Ursula G. Sauer et al.   TOXICOLOGY IN VITRO

Nanotoxicology of common metal oxide based nanomaterials: their ROS-y and non-ROS-y consequences

(2012) Magdiel Inggrid Setyawati et al.   Asia-Pacific Journal of Chemical Engineering

Revealing silver cytotoxicity using Au nanorods/Ag shell nanostructures: disrupting cell membrane and causing apoptosis through oxidative damage

(2012) Xuelian Cheng et al.   RSC Advances

The role of the tumor suppressor p53 pathway in the cellular DNA damage response to zinc oxide nanoparticles

(2011) Kee Woei Ng et al.   BIOMATERIALS

Zinc Oxide Nanoparticles Induce Oxidative Stress and Genotoxicity in Human Liver Cells (HepG2)

(2011) Vyom Sharma et al.   Journal of Biomedical Nanotechnology

The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus

(2011) Yue Zhao et al.   NATURE

Safety Evaluation of Sunscreen Formulations Containing Titanium Dioxide and Zinc Oxide Nanoparticles in UVB Sunburned Skin: An In Vitro and In Vivo Study

(2011) N. A. Monteiro-Riviere et al.   TOXICOLOGICAL SCIENCES

High-throughput 3D spheroid culture and drug testing using a 384 hanging drop array

(2010) Yi-Chung Tung et al.   ANALYST

Bioengineered 3D platform to explore cell–ECM interactions and drug resistance of epithelial ovarian cancer cells

(2010) Daniela Loessner et al.   BIOMATERIALS

Zinc oxide nanoparticles for selective destruction of tumor cells and potential for drug delivery applications

(2010) John W Rasmussen et al.   Expert Opinion on Drug Delivery

Single-walled carbon nanotubes alter Schwann cell behavior differentially within 2D and 3D environments

(2010) Brenda L. Behan et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Immune responses of BALB/c mice to subcutaneously injected multi-walled carbon nanotubes

(2010) Jie Meng et al.   Nanotoxicology

Biomaterials offer cancer research the third dimension

(2010) Dietmar W. Hutmacher   NATURE MATERIALS

Potential Health Impact of Nanoparticles

(2009) Tian Xia et al.   Annual Review of Public Health

HER2 signaling pathway activation and response of breast cancer cells to HER2-targeting agents is dependent strongly on the 3D microenvironment

(2009) Britta Weigelt et al.   BREAST CANCER RESEARCH AND TREATMENT

DNA Damage, Aging, and Cancer

(2009) Jan H.J. Hoeijmakers   NEW ENGLAND JOURNAL OF MEDICINE

Recent advances in three-dimensional multicellular spheroid culture for biomedical research

(2008) Ruei-Zhen Lin et al.   Biotechnology Journal

Collagen I but not Matrigel matrices provide an MMP-dependent barrier to ovarian cancer cell penetration

(2008) Katharine L Sodek et al.   BMC CANCER

Toxicity of nano- and micro-sized ZnO particles in human lung epithelial cells

(2008) Weisheng Lin et al.   JOURNAL OF NANOPARTICLE RESEARCH

From cells to organs: building polarized tissue

(2008) David M. Bryant et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Comparison of 3D and 2D tumor models reveals enhanced HER2 activation in 3D associated with an increased response to trastuzumab

(2008) M Pickl et al.   ONCOGENE

Monolayer and Spheroid Culture of Human Liver Hepatocellular Carcinoma Cell Line Cells Demonstrate Distinct Global Gene Expression Patterns and Functional Phenotypes

(2008) Tammy T. Chang et al.   TISSUE ENGINEERING PART A