Analysis of β2AR-Gs and β2AR-Gi complex formation by NMR spectroscopy

Structure of a Signaling Cannabinoid Receptor 1-G Protein Complex

(2019) Kaavya Krishna Kumar et al.   CELL

Assembly of a GPCR-G Protein Complex

(2019) Yang Du et al.   CELL

Conformational Complexity and Dynamics in a Muscarinic Receptor Revealed by NMR Spectroscopy

(2019) Jun Xu et al.   MOLECULAR CELL

Structures of the M1 and M2 muscarinic acetylcholine receptor/G-protein complexes

(2019) Shoji Maeda et al.   SCIENCE

Mechanism of β2AR regulation by an intracellular positive allosteric modulator

(2019) Xiangyu Liu et al.   SCIENCE

Local membrane charge regulates β2 adrenergic receptor coupling to Gi3

(2019) M. J. Strohman et al.   Nature Communications

Structure and dynamics of GPCR signaling complexes

(2018) Daniel Hilger et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Mechanistic insights into allosteric regulation of the A2A adenosine G protein-coupled receptor by physiological cations

(2018) Libin Ye et al.   Nature Communications

Structure and dynamics of GPCR signaling complexes

(2018) Daniel Hilger et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Cryo-EM structure of the adenosine A2A receptor coupled to an engineered heterotrimeric G protein

(2018) Javier García-Nafría et al.   eLife

Cryo-EM structure of human rhodopsin bound to an inhibitory G protein

(2018) Yanyong Kang et al.   NATURE

Structure of the adenosine-bound human adenosine A1 receptor–Gi complex

(2018) Christopher J. Draper-Joyce et al.   NATURE

Cryo-EM structure of the serotonin 5-HT1B receptor coupled to heterotrimeric Go

(2018) Javier García-Nafría et al.   NATURE

Structure of the µ-opioid receptor–Gi protein complex

(2018) Antoine Koehl et al.   NATURE

The signaling signature of the neurotensin type 1 receptor with endogenous ligands

(2017) Élie Besserer-Offroy et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Single-molecule analysis of ligand efficacy in β2AR–G-protein activation

(2017) G. Glenn Gregorio et al.   NATURE

Structural Insights into the Dynamic Process of β 2 -Adrenergic Receptor Signaling

(2015) Aashish Manglik et al.   CELL

Propagation of conformational changes during μ-opioid receptor activation

(2015) Rémy Sounier et al.   NATURE

The role of protein dynamics in GPCR function: insights from the β2AR and rhodopsin

(2014) Aashish Manglik et al.   CURRENT OPINION IN CELL BIOLOGY

The Dynamic Process of β2-Adrenergic Receptor Activation

(2013) Rie Nygaard et al.   CELL

Lysine methylation strategies for characterizing protein conformations by NMR

(2012) Sacha Thierry Larda et al.   JOURNAL OF BIOMOLECULAR NMR

β2-Adrenergic Receptor Lysosomal Trafficking Is Regulated by Ubiquitination of Lysyl Residues in Two Distinct Receptor Domains

(2011) Kunhong Xiao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal structure of the β2 adrenergic receptor–Gs protein complex

(2011) Søren G. F. Rasmussen et al.   NATURE

Ligand-specific regulation of the extracellular surface of a G-protein-coupled receptor

(2010) Michael P. Bokoch et al.   NATURE