Ginger ( Zingiber officinale Rosc.) and its bioactive components are potential resources for health beneficial agents

Ginger (Zingiber officinale Roscoe) for the treatment and prevention of necrotizing enterocolitis

(2018) Ufuk Cakir et al.   JOURNAL OF ETHNOPHARMACOLOGY

Nine New Gingerols from the Rhizoma of Zingiber officinale and Their Cytotoxic Activities

(2018) Zezhi Li et al.   MOLECULES

Solid phase microextraction and gas chromatography mass spectrometry analysis of Zingiber officinale and Curcuma longa

(2018) Maurizio D'Auria et al.   NATURAL PRODUCT RESEARCH

Ginger polysaccharides induced cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells

(2018) Yun Wang et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Assessment of anti-cancerous potential of 6-gingerol ( Tongling White Ginger) and its synergy with drugs on human cervical adenocarcinoma cells

(2017) Fang Zhang et al.   FOOD AND CHEMICAL TOXICOLOGY

6-Paradol and 6-Shogaol, the Pungent Compounds of Ginger, Promote Glucose Utilization in Adipocytes and Myotubes, and 6-Paradol Reduces Blood Glucose in High-Fat Diet-Fed Mice

(2017) Chien-Kei Wei et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

10-Gingerol, a Phytochemical Derivative from “Tongling White Ginger”, Inhibits Cervical Cancer: Insights into the Molecular Mechanism and Inhibitory Targets

(2017) Fang Zhang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Antioxidant and gastroprotective actions of butanol fraction of Zingiber officinale against diclofenac sodium-induced gastric damage in rats

(2017) Wassila Saiah et al.   JOURNAL OF FOOD BIOCHEMISTRY

A new pyridine alkaloid from Zingiberis rhizoma

(2017) Feng Shao et al.   NATURAL PRODUCT RESEARCH

Ayurvedic preparation of Zingiber officinale Roscoe: effects on cardiac and on smooth muscle parameters

(2017) Alberto Leoni et al.   NATURAL PRODUCT RESEARCH

Two new monoterpenoid glycosides from the fresh rhizome of Tongling White Ginger (Zingiber officinale)

(2017) Tao Guo et al.   NATURAL PRODUCT RESEARCH

6-Gingerol protects intestinal barrier from ischemia/reperfusion-induced damage via inhibition of p38 MAPK to NF-κB signalling

(2017) Yanli Li et al.   PHARMACOLOGICAL RESEARCH

Ginger extract increases muscle mitochondrial biogenesis and serum HDL-cholesterol level in high-fat diet-fed rats

(2017) Soojung Oh et al.   Journal of Functional Foods

Biological activities of ginger against cadmium-induced renal toxicity

(2017) Sami A. Gabr et al.   SAUDI JOURNAL OF BIOLOGICAL SCIENCES

6-Shogaol has anti-amyloidogenic activity and ameliorates Alzheimer’s disease via CysLT1R-mediated inhibition of cathepsin B

(2016) Ji-Young Na et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Pretreatment of 6-shogaol attenuates oxidative stress and inflammation in middle cerebral artery occlusion-induced mice

(2016) Ji-Young Na et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

6-Gingerol Mediates its Anti Tumor Activities in Human Oral and Cervical Cancer Cell Lines through Apoptosis and Cell Cycle Arrest

(2016) Vaishali Kapoor et al.   PHYTOTHERAPY RESEARCH

(S)-[6]-Gingerol enhances glucose uptake in L6 myotubes by activation of AMPK in response to [Ca2+]i

(2016) Yiming Li et al.   JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES

Cancer Chemoprevention Effects of Ginger and its Active Constituents: Potential for New Drug Discovery

(2015) Chong-Zhi Wang et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

1-Dehydro-[14]-Gingerdione, a New Constituent from Zingiber officinale

(2015) D. N. Olennikov et al.   CHEMISTRY OF NATURAL COMPOUNDS

Ginger—Mechanism of action in chemotherapy-induced nausea and vomiting: A review

(2015) Wolfgang Marx et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

6-Shogaol induces cell cycle arrest and apoptosis in human hepatoma cells through pleiotropic mechanisms

(2015) Jung-Ju Wu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

[6]-Gingerol Affects Glucose Metabolism by Dual Regulation via the AMPKα2-Mediated AS160-Rab5 Pathway and AMPK-Mediated Insulin Sensitizing Effects

(2015) Jung Ok Lee et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

The Roman and Islamic spice trade: New archaeological evidence

(2015) Marijke Van der Veen et al.   JOURNAL OF ETHNOPHARMACOLOGY

A Bioactive Constituent of Ginger, 6-Shogaol, Prevents Adipogenesis and Stimulates Lipolysis in 3T3-L1 Adipocytes

(2015) Sujin Suk et al.   JOURNAL OF FOOD BIOCHEMISTRY

Ginger extract prevents high-fat diet-induced obesity in mice via activation of the peroxisome proliferator-activated receptor δ pathway

(2015) Koichi Misawa et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

10-Gingerol inhibits proliferation and invasion of MDA-MB-231 breast cancer cells through suppression of Akt and p38MAPK activity

(2015) JI-HYE JOO et al.   ONCOLOGY REPORTS

Proteasome inhibition mediates p53 reactivation and anti-cancer activity of 6-Gingerol in cervical cancer cells

(2015) Namrata Rastogi et al.   Oncotarget

Anthelmintic constituents from ginger (Zingiber officinale) against Hymenolepis nana

(2014) Rong-Jyh Lin et al.   ACTA TROPICA

6-Shogaol, an active constituent of ginger, attenuates neuroinflammation and cognitive deficits in animal models of dementia

(2014) Minho Moon et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Ginger extract diminishes chronic fructose consumption-induced kidney injury through suppression of renal overexpression of proinflammatory cytokines in rats

(2014) Ming Yang et al.   BMC Complementary and Alternative Medicine

Anti-cancer activity of Ginger (Zingiber officinale) leaf through the expression of activating transcription factor 3 in human colorectal cancer cells

(2014) Gwang Hun Park et al.   BMC Complementary and Alternative Medicine

6-Shogaol from Dried Ginger Inhibits Growth of Prostate Cancer Cells Both In Vitro and In Vivo through Inhibition of STAT3 and NF- B Signaling

(2014) A. Saha et al.   Cancer Prevention Research

Acute administration of ginger (Zingiber officinale rhizomes) extract on timed intravenous pentylenetetrazol infusion seizure model in mice

(2014) Abdolkarim Hosseini et al.   EPILEPSY RESEARCH

[10]-Gingerol induces mitochondrial apoptosis through activation of MAPK pathway in HCT116 human colon cancer cells

(2014) Min Ju Ryu et al.   IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL

Inhibition of Angiotensin-1-Converting Enzyme Activity by Two Varieties of Ginger (Zingiber officinale) in Rats Fed a High Cholesterol Diet

(2014) Ayodele Jacob Akinyemi et al.   JOURNAL OF MEDICINAL FOOD

Ginger improves cognitive function via NGF-induced ERK/CREB activation in the hippocampus of the mouse

(2014) Soonmin Lim et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Anti-obesity action of gingerol: effect on lipid profile, insulin, leptin, amylase and lipase in male obese rats induced by a high-fat diet

(2014) Ganapathy Saravanan et al.   JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE

A systematic review and meta-analysis of the effect and safety of ginger in the treatment of pregnancy-associated nausea and vomiting

(2014) Estelle Viljoen et al.   Nutrition Journal

6-Shogaol, an active compound of ginger, protects dopaminergic neurons in Parkinson's disease models via anti-neuroinflammation

(2013) Gunhyuk Park et al.   ACTA PHARMACOLOGICA SINICA

[8]-Gingerol inhibits melanogenesis in murine melanoma cells through down-regulation of the MAPK and PKA signal pathways

(2013) Huey-Chun Huang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Phenylalkanoids from Zingiber officinale

(2013) Wei-Jen Li et al.   CHEMISTRY OF NATURAL COMPOUNDS

Anti-neuroinflammatory capacity of fresh ginger is attributed mainly to 10-gingerol

(2013) Su-Chen Ho et al.   FOOD CHEMISTRY

6-Gingerol prevents adipogenesis and the accumulation of cytoplasmic lipid droplets in 3T3-L1 cells

(2013) Thing-Fong Tzeng et al.   PHYTOMEDICINE

6-Gingerol Inhibits Rosiglitazone-Induced Adipogenesis in 3T3-L1 Adipocytes

(2013) Thing-Fong Tzeng et al.   PHYTOTHERAPY RESEARCH

[6]-Gingerol: A Novel AT1 Antagonist for the Treatment of Cardiovascular Disease

(2013) Qing Liu et al.   PLANTA MEDICA

[6]-Shogaol inhibits melanogenesis in B16 mouse melanoma cells through activation of the ERK pathway

(2012) Cheng Yao et al.   ACTA PHARMACOLOGICA SINICA

Phenylpropanoid ester from Zingiber officinale and their inhibitory effects on the production of nitric oxide

(2012) Seong Su Hong et al.   ARCHIVES OF PHARMACAL RESEARCH

An Impression on Current Developments in the Technology, Chemistry, and Biological Activities of Ginger (Zingiber officinaleRoscoe)

(2012) I. Rahath Kubra et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Safety of ginger use in pregnancy: results from a large population-based cohort study

(2012) Kristine Heitmann et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

6-Gingerol Inhibits Growth of Colon Cancer Cell LoVo via Induction of G2/M Arrest

(2012) Ching-Bin Lin et al.   Evidence-based Complementary and Alternative Medicine

Cytotoxic, cytoprotective and antioxidant effects of isolated phenolic compounds from fresh ginger

(2012) Fang Peng et al.   FITOTERAPIA

Inhibitory effect of galanolactone isolated from Zingiber officinale roscoe extract on adipogenesis in 3T3-L1 cells

(2012) Eun-Kyung Ahn et al.   Journal of the Korean Society for Applied Biological Chemistry

Zingiber officinale extract exhibits antidiabetic potential via modulating glucose uptake, protein glycation and inhibiting adipocyte differentiation: an in vitro study

(2012) M Priya Rani et al.   JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE

6-Gingerol Induces Apoptosis through Lysosomal-Mitochondrial Axis in Human Hepatoma G2 Cells

(2012) Guang Yang et al.   PHYTOTHERAPY RESEARCH

Examination of the Pharmacokinetics of Active Ingredients of Ginger in Humans

(2011) Yanke Yu et al.   AAPS Journal

The conformation and CETP inhibitory activity of [10]-dehydrogingerdione isolated from Zingiber officinale

(2011) Soon-Yong Choi et al.   ARCHIVES OF PHARMACAL RESEARCH

Inhibitory Effect of [6]-Gingerol on Melanogenesis in B16F10 Melanoma Cells and a Possible Mechanism of Action

(2011) Huey-Chun HUANG et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Beneficial effects of ginger (Zingiber officinale) on carbohydrate metabolism in streptozotocin-induced diabetic rats

(2011) Nafiu Bidemi Abdulrazaq et al.   BRITISH JOURNAL OF NUTRITION

Potential antioxidant activities in vitro of polysaccharides extracted from ginger (Zingiber officinale)

(2011) Zhongshan Zhang et al.   CARBOHYDRATE POLYMERS

Update on the Chemopreventive Effects of Ginger and its Phytochemicals

(2011) Manjeshwar Shrinath Baliga et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Phenolic compounds isolated from Zingiber officinale roots inhibit cell adhesion

(2011) Seung Woong Lee et al.   FOOD CHEMISTRY

Hepatoprotective effect of methanol extracts of Zingiber officinale and Cichorium intybus

(2011) AH Atta et al.   INDIAN JOURNAL OF PHARMACEUTICAL SCIENCES

Chemical Constituents and Their Bioactivities of “Tongling White Ginger” (Zingiber officinale)

(2011) Tao Feng et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

4-Shogaol, an Active Constituent of Dietary Ginger, Inhibits Metastasis of MDA-MB-231 Human Breast Adenocarcinoma Cells by Decreasing the Repression of NF-κB/Snail on RKIP

(2011) Ya-Ling Hsu et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Synthesis of a New [6]-Gingerol Analogue and Its Protective Effect with Respect to the Development of Metabolic Syndrome in Mice Fed a High-Fat Diet

(2011) Mayumi Okamoto et al.   JOURNAL OF MEDICINAL CHEMISTRY

Two new phenylalkanoids from the rhizomes ofZingiber officinale

(2011) Chung-Yi Chen et al.   NATURAL PRODUCT RESEARCH

A new phenylalkanoid from the rhizomes ofZingiber officinale

(2011) Soong-Yu Kuo et al.   NATURAL PRODUCT RESEARCH

Ginger (Zingiber officinale) reduces acute chemotherapy-induced nausea: a URCC CCOP study of 576 patients

(2011) Julie L. Ryan et al.   SUPPORTIVE CARE IN CANCER

Larvicidal activities of ginger (Zingiber officinale) against Angiostrongylus cantonensis

(2010) Rong-Jyh Lin et al.   ACTA TROPICA

Ginger ingredients inhibit the development of diethylnitrosoamine induced premalignant phenotype in rat chemical hepatocarcinogenesis model

(2010) Mahmoud A. Mansour et al.   BIOFACTORS

Protective effect of dietary ginger on antioxidant enzymes and oxidative damage in experimental diabetic rat tissues

(2010) Kondeti Ramudu Shanmugam et al.   FOOD CHEMISTRY

Synthesis of Phenolics and Flavonoids in Ginger (Zingiber officinale Roscoe) and Their Effects on Photosynthesis Rate

(2010) Ali Ghasemzadeh et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Inhibitory effects of zingerone, a pungent component of Zingiber officinale Roscoe, on colonic motility in rats

(2010) Momoe Iwami et al.   Journal of Natural Medicines

Anti-invasion effects of 6-shogaol and 6-gingerol, two active components in ginger, on human hepatocarcinoma cells

(2010) Chia-Jui Weng et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Anti-emetic effect of ginger powder versus placebo as an add-on therapy in children and young adults receiving high emetogenic chemotherapy

(2010) Anu Kochanujan Pillai et al.   PEDIATRIC BLOOD & CANCER

[6]-Gingerol Suppresses Colon Cancer Growth by Targeting Leukotriene A4 Hydrolase

(2009) Chul-Ho Jeong et al.   CANCER RESEARCH

Effect of [10]-Gingerol on [Ca2+]i and Cell Death in Human Colorectal Cancer Cells

(2009) Chung-Yi Chen et al.   MOLECULES

6-Shogaol and 6-gingerol, the pungent of ginger, inhibit TNF-α mediated downregulation of adiponectin expression via different mechanisms in 3T3-L1 adipocytes

(2008) Yasuka Isa et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Plasma pharmacokinetics and tissue distribution of [6]-gingerol in rats

(2008) Su-zhen Jiang et al.   BIOPHARMACEUTICS & DRUG DISPOSITION

Pharmacokinetics of 6-Gingerol, 8-Gingerol, 10-Gingerol, and 6-Shogaol and Conjugate Metabolites in Healthy Human Subjects

(2008) S. M. Zick et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Protein and Ginger for the Treatment of Chemotherapy-Induced Delayed Nausea

(2008) Max E. Levine et al.   JOURNAL OF ALTERNATIVE AND COMPLEMENTARY MEDICINE

Diarylheptanoids and a Monoterpenoid from the Rhizomes ofZingiber officinale: Antioxidant and Cytoprotective Properties

(2008) Qiao Feng Tao et al.   JOURNAL OF NATURAL PRODUCTS

Mosquito larvicidal activity of isolated compounds from the rhizome of Zingiber officinale

(2008) A. Abdul Rahuman et al.   PHYTOTHERAPY RESEARCH

Phase II trial of encapsulated ginger as a treatment for chemotherapy-induced nausea and vomiting

(2008) Suzanna M. Zick et al.   SUPPORTIVE CARE IN CANCER