The conserved elongation factor Spn1 is required for normal transcription, histone modifications, and splicing in Saccharomyces cerevisiae

A Collection of Pre-mRNA Splicing Mutants in Arabidopsis thaliana

(2020) Tatsuo Kanno et al.   G3-Genes Genomes Genetics

A conserved genetic interaction between Spt6 and Set2 regulates H3K36 methylation

(2019) Rajaraman Gopalakrishnan et al.   NUCLEIC ACIDS RESEARCH

Spt6 Association with RNA Polymerase II Directs mRNA Turnover During Transcription

(2018) Raghuvar Dronamraju et al.   MOLECULAR CELL

Casein kinase 2 mediated phosphorylation of Spt6 modulates histone dynamics and regulates spurious transcription

(2018) Emmanuelle Gouot et al.   NUCLEIC ACIDS RESEARCH

H3K4 Methylation Dependent and Independent Chromatin Regulation by JHD2 and SET1 in Budding Yeast

(2018) Kwan Yin Lee et al.   G3-Genes Genomes Genetics

Structure of activated transcription complex Pol II–DSIF–PAF–SPT6

(2018) Seychelle M. Vos et al.   NATURE

Genetic ablation of interacting with Spt6 (Iws1) causes early embryonic lethality

(2018) Arturo Orlacchio et al.   PLoS One

Spt6 Is Required for the Fidelity of Promoter Selection

(2018) Stephen M. Doris et al.   MOLECULAR CELL

Casein Kinase II Phosphorylation of Spt6 Enforces Transcriptional Fidelity by Maintaining Spn1-Spt6 Interaction

(2018) Raghuvar Dronamraju et al.   Cell Reports

RNA Binding by Histone Methyltransferases Set1 and Set2

(2017) Camille Sayou et al.   MOLECULAR AND CELLULAR BIOLOGY

Determinants of Histone H3K4 Methylation Patterns

(2017) Luis M. Soares et al.   MOLECULAR CELL

The elongation factor Spn1 is a multi-functional chromatin binding protein

(2017) Sha Li et al.   NUCLEIC ACIDS RESEARCH

Bidirectional terminators in Saccharomyces cerevisiae prevent cryptic transcription from invading neighboring genes

(2017) Nicole Uwimana et al.   NUCLEIC ACIDS RESEARCH

A novel SH2 recognition mechanism recruits Spt6 to the doubly phosphorylated RNA polymerase II linker at sites of transcription

(2017) Matthew A Sdano et al.   eLife

Combinatorial Histone Readout by the Dual Plant Homeodomain (PHD) Fingers of Rco1 Mediates Rpd3S Chromatin Recruitment and the Maintenance of Transcriptional Fidelity

(2016) Stephen L. McDaniel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Native Elongating Transcript Sequencing Reveals Human Transcriptional Activity at Nucleotide Resolution

(2015) Andreas Mayer et al.   CELL

StringTie enables improved reconstruction of a transcriptome from RNA-seq reads

(2015) Mihaela Pertea et al.   NATURE BIOTECHNOLOGY

Balancing acts of SRI and an auto-inhibitory domain specify Set2 function at transcribed chromatin

(2015) Yi Wang et al.   NUCLEIC ACIDS RESEARCH

Histone Deacetylases and Phosphorylated Polymerase II C-Terminal Domain Recruit Spt6 for Cotranscriptional Histone Reassembly

(2014) B. B. Burugula et al.   MOLECULAR AND CELLULAR BIOLOGY

Phosphoproteomics Screen Reveals Akt Isoform-Specific Signals Linking RNA Processing to Lung Cancer

(2014) Ioannis Sanidas et al.   MOLECULAR CELL

Cell cycle population effects in perturbation studies

(2014) E. O'Duibhir et al.   Molecular Systems Biology

The Reference Genome Sequence of Saccharomyces cerevisiae : Then and Now

(2014) Stacia R. Engel et al.   G3-Genes Genomes Genetics

Gene promoters dictate histone occupancy within genes

(2013) Roberto Perales et al.   EMBO JOURNAL

Spt6 Regulates Intragenic and Antisense Transcription, Nucleosome Positioning, and Histone Modifications Genome-Wide in Fission Yeast

(2013) C. M. DeGennaro et al.   MOLECULAR AND CELLULAR BIOLOGY

Extensive transcriptional heterogeneity revealed by isoform profiling

(2013) Vicent Pelechano et al.   NATURE

A feed forward circuit comprising Spt6, Ctk1 and PAF regulates Pol II CTD phosphorylation and transcription elongation

(2013) R. Dronamraju et al.   NUCLEIC ACIDS RESEARCH

A Compendium of Nucleosome and Transcript Profiles Reveals Determinants of Chromatin Architecture and Transcription

(2013) Harm van Bakel et al.   PLoS Genetics

TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions

(2013) Daehwan Kim et al.   GENOME BIOLOGY

Fast gapped-read alignment with Bowtie 2

(2012) Ben Langmead et al.   NATURE METHODS

HIGH NITROGEN INSENSITIVE 9 (HNI9)-mediated systemic repression of root NO3−uptake is associated with changes in histone methylation

(2011) Thomas Widiez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

BEDTools: a flexible suite of utilities for comparing genomic features

(2010) Aaron R. Quinlan et al.   BIOINFORMATICS

The structure of an Iws1/Spt6 complex reveals an interaction domain conserved in TFIIS, Elongin A and Med26

(2010) Marie-Laure Diebold et al.   EMBO JOURNAL

Intergenic transcription causes repression by directing nucleosome assembly

(2010) S. J. Hainer et al.   GENES & DEVELOPMENT

A Nucleosome Surface Formed by Histone H4, H2A, and H3 Residues Is Needed for Proper Histone H3 Lys36Methylation, Histone Acetylation, and Repression of Cryptic Transcription

(2010) Hai-Ning Du et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Transcription Factor Spn1 Regulates Gene Expression via a Highly Conserved Novel Structural Motif

(2010) Venugopal Pujari et al.   JOURNAL OF MOLECULAR BIOLOGY

Control of Chromatin Structure by Spt6: Different Consequences in Coding and Regulatory Regions

(2010) I. Ivanovska et al.   MOLECULAR AND CELLULAR BIOLOGY

Phosphorylated Pol II CTD Recruits Multiple HDACs, Including Rpd3C(S), for Methylation-Dependent Deacetylation of ORF Nucleosomes

(2010) Chhabi K. Govind et al.   MOLECULAR CELL

Structure and Biological Importance of the Spn1-Spt6 Interaction, and Its Regulatory Role in Nucleosome Binding

(2010) Seth M. McDonald et al.   MOLECULAR CELL

Uniform transitions of the general RNA polymerase II transcription complex

(2010) Andreas Mayer et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

DSIF and RNA Polymerase II CTD Phosphorylation Coordinate the Recruitment of Rpd3S to Actively Transcribed Genes

(2010) Simon Drouin et al.   PLoS Genetics

The Sequence Alignment/Map format and SAMtools

(2009) H. Li et al.   BIOINFORMATICS

Histone H3 Lysine 36 Dimethylation (H3K36me2) Is Sufficient to Recruit the Rpd3s Histone Deacetylase Complex and to Repress Spurious Transcription

(2009) Bing Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Progression through the RNA Polymerase II CTD Cycle

(2009) Stephen Buratowski   MOLECULAR CELL

An auxin-based degron system for the rapid depletion of proteins in nonplant cells

(2009) Kohei Nishimura et al.   NATURE METHODS

Histone H3 K36 methylation is mediated by a trans-histone methylation pathway involving an interaction between Set2 and histone H4

(2008) H.-N. Du et al.   GENES & DEVELOPMENT

The Iws1:Spt6:CTD complex controls cotranscriptional mRNA biosynthesis and HYPB/Setd2-mediated histone H3K36 methylation

(2008) S. M. Yoh et al.   GENES & DEVELOPMENT

Roles for Ctk1 and Spt6 in Regulating the Different Methylation States of Histone H3 Lysine 36

(2008) M. L. Youdell et al.   MOLECULAR AND CELLULAR BIOLOGY

Chromatin- and Transcription-Related Factors Repress Transcription from within Coding Regions throughout the Saccharomyces cerevisiae Genome

(2008) Vanessa Cheung et al.   PLOS BIOLOGY

Model-based Analysis of ChIP-Seq (MACS)

(2008) Yong Zhang et al.   GENOME BIOLOGY