Spt6 Regulates Intragenic and Antisense Transcription, Nucleosome Positioning, and Histone Modifications Genome-Wide in Fission Yeast

The histone chaperone Spt6 coordinates histone H3K27 demethylation and myogenesis

(2013) A Hongjun Wang et al.   EMBO JOURNAL

Long Noncoding RNAs: Past, Present, and Future

(2013) J. T. Y. Kung et al.   GENETICS

Spt6 prevents transcription-coupled loss of posttranslationally modified histone H3

(2013) Hiroaki Kato et al.   Scientific Reports

A Compendium of Nucleosome and Transcript Profiles Reveals Determinants of Chromatin Architecture and Transcription

(2013) Harm van Bakel et al.   PLoS Genetics

Long non-coding RNAs and human disease

(2012) Lorna W. Harries   BIOCHEMICAL SOCIETY TRANSACTIONS

Transcription-associated histone modifications and cryptic transcription

(2012) Michaela Smolle et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

The many roles of the conserved eukaryotic Paf1 complex in regulating transcription, histone modifications, and disease states

(2012) Brett N. Tomson et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

CHD1 remodelers regulate nucleosome spacingin vitroand align nucleosomal arrays over gene coding regions inS. pombe

(2012) Julia Pointner et al.   EMBO JOURNAL

Hrp3 controls nucleosome positioning to suppress non-coding transcription in eu- and heterochromatin

(2012) Young Sam Shim et al.   EMBO JOURNAL

Chd1 chromatin remodelers maintain nucleosome organization and repress cryptic transcription

(2012) Bianca P Hennig et al.   EMBO REPORTS

The histone H3 Lys 27 demethylase JMJD3 regulates gene expression by impacting transcriptional elongation

(2012) S. Chen et al.   GENES & DEVELOPMENT

The Histone Chaperone Spt6 Is Required for Activation-induced Cytidine Deaminase Target Determination through H3K4me3 Regulation

(2012) Nasim A. Begum et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Chromatin remodelers Isw1 and Chd1 maintain chromatin structure during transcription by preventing histone exchange

(2012) Michaela Smolle et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Spt6 levels are modulated by PAAF1 and proteasome to regulate the HIV-1 LTR

(2012) Mirai Nakamura et al.   Retrovirology

Two Distinct Repressive Mechanisms for Histone 3 Lysine 4 Methylation through Promoting 3′-End Antisense Transcription

(2012) Thanasis Margaritis et al.   PLoS Genetics

Pervasive transcription – Lessons from yeast

(2011) Mathieu Tisseur et al.   BIOCHIMIE

Solution Structure of Tandem SH2 Domains from Spt6 Protein and Their Binding to the Phosphorylated RNA Polymerase II C-terminal Domain

(2011) Jianping Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal Structures of the S. cerevisiae Spt6 Core and C-Terminal Tandem SH2 Domain

(2011) Devin Close et al.   JOURNAL OF MOLECULAR BIOLOGY

Chromatin Reassembly Factors Are Involved in Transcriptional Interference Promoting HIV Latency

(2011) E. Gallastegui et al.   JOURNAL OF VIROLOGY

Spt6 Is Required for Heterochromatic Silencing in the Fission Yeast Schizosaccharomyces pombe

(2011) C. M. Kiely et al.   MOLECULAR AND CELLULAR BIOLOGY

Asf1/HIRA Facilitate Global Histone Deacetylation and Associate with HP1 to Promote Nucleosome Occupancy at Heterochromatic Loci

(2011) Kenichi Yamane et al.   MOLECULAR CELL

Systematic bias in high-throughput sequencing data and its correction by BEADS

(2011) Ming-Sin Cheung et al.   NUCLEIC ACIDS RESEARCH

A Role for Snf2-Related Nucleosome-Spacing Enzymes in Genome-Wide Nucleosome Organization

(2011) T. Gkikopoulos et al.   SCIENCE

Clr4/Suv39 and RNA Quality Control Factors Cooperate to Trigger RNAi and Suppress Antisense RNA

(2011) K. Zhang et al.   SCIENCE

The structure of an Iws1/Spt6 complex reveals an interaction domain conserved in TFIIS, Elongin A and Med26

(2010) Marie-Laure Diebold et al.   EMBO JOURNAL

Combinatorial, site-specific requirement for heterochromatic silencing factors in the elimination of nucleosome-free regions

(2010) J. F. Garcia et al.   GENES & DEVELOPMENT

A Nucleosome Surface Formed by Histone H4, H2A, and H3 Residues Is Needed for Proper Histone H3 Lys36Methylation, Histone Acetylation, and Repression of Cryptic Transcription

(2010) Hai-Ning Du et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Noncanonical Tandem SH2 Enables Interaction of Elongation Factor Spt6 with RNA Polymerase II

(2010) Marie-Laure Diebold et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Tandem SH2 Domain in Transcription Elongation Factor Spt6 Binds the Phosphorylated RNA Polymerase II C-terminal Repeat Domain (CTD)

(2010) Mai Sun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Transcription Factor Spn1 Regulates Gene Expression via a Highly Conserved Novel Structural Motif

(2010) Venugopal Pujari et al.   JOURNAL OF MOLECULAR BIOLOGY

Control of Chromatin Structure by Spt6: Different Consequences in Coding and Regulatory Regions

(2010) I. Ivanovska et al.   MOLECULAR AND CELLULAR BIOLOGY

TopHat: discovering splice junctions with RNA-Seq

(2009) Cole Trapnell et al.   BIOINFORMATICS

Spt6 enhances the elongation rate of RNA polymerase II in vivo

(2009) M Behfar Ardehali et al.   EMBO JOURNAL

Direct Bre1-Paf1 Complex Interactions and RING Finger-independent Bre1-Rad6 Interactions Mediate Histone H2B Ubiquitylation in Yeast

(2009) Jaehoon Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Fission Yeast HIRA Histone Chaperone Is Required for Promoter Silencing and the Suppression of Cryptic Antisense Transcripts

(2009) H. E. Anderson et al.   MOLECULAR AND CELLULAR BIOLOGY

Set2-Dependent K36 Methylation Is Regulated by Novel Intratail Interactions within H3

(2009) J. N. Psathas et al.   MOLECULAR AND CELLULAR BIOLOGY

Histone H2A.Z cooperates with RNAi and heterochromatin factors to suppress antisense RNAs

(2009) Martin Zofall et al.   NATURE

MEME SUITE: tools for motif discovery and searching

(2009) T. L. Bailey et al.   NUCLEIC ACIDS RESEARCH

The Set2/Rpd3S Pathway Suppresses Cryptic Transcription without Regard to Gene Length or Transcription Frequency

(2009) Colin R. Lickwar et al.   PLoS One

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

(2009) Ben Langmead et al.   GENOME BIOLOGY

Requirements for chromatin reassembly during transcriptional downregulation of a heat shock gene in Saccharomyces cerevisiae

(2008) Mette M. Jensen et al.   FEBS Journal

Histone H3 K36 methylation is mediated by a trans-histone methylation pathway involving an interaction between Set2 and histone H4

(2008) H.-N. Du et al.   GENES & DEVELOPMENT

The S. pombe SAGA complex controls the switch from proliferation to sexual differentiation through the opposing roles of its subunits Gcn5 and Spt8

(2008) D. Helmlinger et al.   GENES & DEVELOPMENT

The Iws1:Spt6:CTD complex controls cotranscriptional mRNA biosynthesis and HYPB/Setd2-mediated histone H3K36 methylation

(2008) S. M. Yoh et al.   GENES & DEVELOPMENT

Crystal Structure and RNA Binding of the Tex Protein from Pseudomonas aeruginosa

(2008) Sean J. Johnson et al.   JOURNAL OF MOLECULAR BIOLOGY

Roles for Ctk1 and Spt6 in Regulating the Different Methylation States of Histone H3 Lysine 36

(2008) M. L. Youdell et al.   MOLECULAR AND CELLULAR BIOLOGY

Design and analysis of ChIP-seq experiments for DNA-binding proteins

(2008) Peter V Kharchenko et al.   NATURE BIOTECHNOLOGY

TRAMP-mediated RNA surveillance prevents spurious entry of RNAs into the Schizosaccharomyces pombe siRNA pathway

(2008) Marc Bühler et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Chromatin- and Transcription-Related Factors Repress Transcription from within Coding Regions throughout the Saccharomyces cerevisiae Genome

(2008) Vanessa Cheung et al.   PLOS BIOLOGY