TrkB reduction exacerbates Alzheimer’s disease-like signaling aberrations and memory deficits without affecting β-amyloidosis in 5XFAD mice

Activity-Dependent p25 Generation Regulates Synaptic Plasticity and Aβ-Induced Cognitive Impairment

(2014) Jinsoo Seo et al.   CELL

Synaptic and Cognitive Improvements by Inhibition of 2-AG Metabolism Are through Upregulation of MicroRNA-188-3p in a Mouse Model of Alzheimer's Disease

(2014) J. Zhang et al.   JOURNAL OF NEUROSCIENCE

Social Interaction Rescues Memory Deficit in an Animal Model of Alzheimer's Disease by Increasing BDNF-Dependent Hippocampal Neurogenesis

(2014) Ya-Hsin Hsiao et al.   JOURNAL OF NEUROSCIENCE

PERK mediates eIF2α phosphorylation responsible for BACE1 elevation, CREB dysfunction and neurodegeneration in a mouse model of Alzheimer's disease

(2014) Latha Devi et al.   NEUROBIOLOGY OF AGING

7,8-Dihydroxyflavone, a Small Molecule TrkB Agonist, Improves Spatial Memory and Increases Thin Spine Density in a Mouse Model of Alzheimer Disease-Like Neuronal Loss

(2014) Nicholas A. Castello et al.   PLoS One

Impairment of nesting behaviour in 3xTg-AD mice

(2013) Virginia Torres-Lista et al.   BEHAVIOURAL BRAIN RESEARCH

BDNF Val66Met, Aβ amyloid, and cognitive decline in preclinical Alzheimer's disease

(2013) Yen Ying Lim et al.   NEUROBIOLOGY OF AGING

7,8-Dihydroxyflavone Prevents Synaptic Loss and Memory Deficits in a Mouse Model of Alzheimer’s Disease

(2013) Zhentao Zhang et al.   NEUROPSYCHOPHARMACOLOGY

The Impact of Bdnf Gene Deficiency to the Memory Impairment and Brain Pathology of APPswe/PS1dE9 Mouse Model of Alzheimer’s Disease

(2013) Tomi Rantamäki et al.   PLoS One

Polymorphism of brain derived neurotrophic factor influences β amyloid load in cognitively intact apolipoprotein E ε4 carriers

(2013) Katarzyna Adamczuk et al.   NeuroImage-Clinical

Genetic Knockdown of Brain-Derived Neurotrophic Factor in 3xTg-AD Mice Does Not Alter Aβ or Tau Pathology

(2012) Nicholas A. Castello et al.   PLoS One

Monoacylglycerol Lipase Is a Therapeutic Target for Alzheimer's Disease

(2012) Rongqing Chen et al.   Cell Reports

Epigenetic Enhancement of BDNF Signaling Rescues Synaptic Plasticity in Aging

(2011) Y. Zeng et al.   JOURNAL OF NEUROSCIENCE

Running is the neurogenic and neurotrophic stimulus in environmental enrichment

(2011) T. Kobilo et al.   LEARNING & MEMORY

Impaired TrkB receptor signaling contributes to memory impairment in APP/PS1 mice

(2011) Susanna Kemppainen et al.   NEUROBIOLOGY OF AGING

Enriched housing reverses age-associated impairment of cognitive functions and tPA-dependent maturation of BDNF

(2011) Pauline Obiang et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Reduced Cell Proliferation and Neuroblast Differentiation in the Dentate Gyrus of High Fat Diet-Fed Mice are Ameliorated by Metformin and Glimepiride Treatment

(2011) Dae Young Yoo et al.   NEUROCHEMICAL RESEARCH

Increasing CREB Function in the CA1 Region of Dorsal Hippocampus Rescues the Spatial Memory Deficits in a Mouse Model of Alzheimer's Disease

(2011) Adelaide P Yiu et al.   NEUROPSYCHOPHARMACOLOGY

7,8-Dihydroxyflavone, a Small-Molecule TrkB Agonist, Reverses Memory Deficits and BACE1 Elevation in a Mouse Model of Alzheimer's Disease

(2011) Latha Devi et al.   NEUROPSYCHOPHARMACOLOGY

Age and gene overexpression interact to abolish nesting behavior in Tg2576 amyloid precursor protein (APP) mice

(2010) Daniel W. Wesson et al.   BEHAVIOURAL BRAIN RESEARCH

Microarray Analysis of Hippocampal CA1 Neurons Implicates Early Endosomal Dysfunction During Alzheimer's Disease Progression

(2010) Stephen D. Ginsberg et al.   BIOLOGICAL PSYCHIATRY

Partial reduction of BACE1 improves synaptic plasticity, recent and remote memories in Alzheimer’s disease transgenic mice

(2010) Ryoichi Kimura et al.   JOURNAL OF NEUROCHEMISTRY

AGEs/RAGE complex upregulates BACE1 via NF-κB pathway activation

(2010) Michela Guglielmotto et al.   NEUROBIOLOGY OF AGING

Treadmill exercise represses neuronal cell death in an aged transgenic mouse model of Alzheimer's disease

(2010) Hyun-Sub Um et al.   NEUROSCIENCE RESEARCH

Sex- and brain region-specific acceleration of β-amyloidogenesis following behavioral stress in a mouse model of Alzheimer's disease

(2010) Latha Devi et al.   Molecular Brain

Age-related cognitive decline and nesting behavior in an APPswe/PS1 bigenic model of Alzheimer's disease

(2009) Mohammed Filali et al.   BRAIN RESEARCH

Genetic reductions of β-site amyloid precursor protein-cleaving enzyme 1 and amyloid-β ameliorate impairment of conditioned taste aversion memory in 5XFAD Alzheimer’s disease model mice

(2009) Latha Devi et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Brain-Derived Neurotrophic Factor Reduces Amyloidogenic Processing through Control of SORLA Gene Expression

(2009) M. Rohe et al.   JOURNAL OF NEUROSCIENCE

Neuroprotective effects of brain-derived neurotrophic factor in rodent and primate models of Alzheimer's disease

(2009) Alan H Nagahara et al.   NATURE MEDICINE

Brain-derived neurotrophic factor in neurodegenerative diseases

(2009) Chiara Zuccato et al.   Nature Reviews Neurology

TrkB signalling pathways in LTP and learning

(2009) Liliana Minichiello   NATURE REVIEWS NEUROSCIENCE

Failures to reconsolidate memory in a mouse model of Alzheimer’s disease

(2009) Masuo Ohno   NEUROBIOLOGY OF LEARNING AND MEMORY

Adverse Stress, Hippocampal Networks, and Alzheimer’s Disease

(2009) Sarah M. Rothman et al.   NEUROMOLECULAR MEDICINE

Age-dependent and -independent behavioral deficits in Tg2576 mice

(2008) R.M.J. Deacon et al.   BEHAVIOURAL BRAIN RESEARCH

New insights into brain BDNF function in normal aging and Alzheimer disease

(2008) Lucia Tapia-Arancibia et al.   BRAIN RESEARCH REVIEWS

Cognitive and non-cognitive behaviors in an APPswe/PS1 bigenic model of Alzheimer’s disease

(2008) M. Filali et al.   GENES BRAIN AND BEHAVIOR

BDNF and the diseased nervous system: a delicate balance between adaptive and pathological processes of gene regulation

(2008) Yinghui Hu et al.   JOURNAL OF NEUROCHEMISTRY

Protective effect of BDNF against beta-amyloid induced neurotoxicity in vitro and in vivo in rats

(2008) S. Arancibia et al.   NEUROBIOLOGY OF DISEASE

Impairments in remote memory stabilization precede hippocampal synaptic and cognitive failures in 5XFAD Alzheimer mouse model

(2008) Ryoichi Kimura et al.   NEUROBIOLOGY OF DISEASE

Upregulation of hippocampal TrkB and synaptotagmin is involved in treadmill exercise-enhanced aversive memory in mice

(2008) Yu-Fan Liu et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

NGF and BDNF signaling control amyloidogenic route and A  production in hippocampal neurons

(2008) C. Matrone et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TrkB but not trkC receptors are necessary for postnatal maintenance of hippocampal spines

(2007) O. von Bohlen und Halbach et al.   NEUROBIOLOGY OF AGING