Synergistic antitumor interaction of valproic acid and simvastatin sensitizes prostate cancer to docetaxel by targeting CSCs compartment via YAP inhibition
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Title
Synergistic antitumor interaction of valproic acid and simvastatin sensitizes prostate cancer to docetaxel by targeting CSCs compartment via YAP inhibition
Authors
Keywords
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Journal
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
Volume 39, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2020-10-08
DOI
10.1186/s13046-020-01723-7
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Note: Only part of the references are listed.- Toxicity of diatom-derived polyunsaturated aldehyde mixtures on sea urchin Paracentrotus lividus development
- (2019) Nadia Ruocco et al. Scientific Reports
- Characterization of OCT3/4, Nestin, NANOG, CD44 and CD24 as stem cell markers in canine prostate cancer
- (2019) Camila Dorotea Costa et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Epigenetic Control of Gene Expression in the Normal and Malignant Human Prostate: A Rapid Response Which Promotes Therapeutic Resistance
- (2019) Fiona M. Frame et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- The Hippo Pathway in Prostate Cancer
- (2019) Salem et al. Cells
- CD44 Promotes Migration and Invasion of Docetaxel-Resistant Prostate Cancer Cells Likely via Induction of Hippo-Yap Signaling
- (2019) Chih-Jen Lai et al. Cells
- Radiation-induced glucocorticoid receptor promotes CD44+ prostate cancer stem cell growth through activation of SGK1-Wnt/β-catenin signaling
- (2019) Feng Chen et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Vorinostat Potentiates 5-Fluorouracil/Cisplatin Combination by Inhibiting Chemotherapy-Induced EGFR Nuclear Translocation and Increasing Cisplatin Uptake
- (2019) Geny Piro et al. MOLECULAR CANCER THERAPEUTICS
- Implication for Cancer Stem Cells in Solid Cancer Chemo-Resistance: Promising Therapeutic Strategies Based on the Use of HDAC Inhibitors.
- (2019) Roca et al. Journal of Clinical Medicine
- The Role of Metabolic Plasticity in Blood and Brain Stem Cell Pathophysiology
- (2019) Catherine J Libby et al. CANCER RESEARCH
- Self-Assembling Scaffolds Supported Long-Term Growth of Human Primed Embryonic Stem Cells and Upregulated Core and Naïve Pluripotent Markers
- (2019) Christina McKee et al. Cells
- Valproic acid sensitizes metformin-resistant human renal cell carcinoma cells by upregulating H3 acetylation and EMT reversal
- (2018) Muyun Wei et al. BMC CANCER
- Chemohormonal Therapy in Metastatic Hormone-Sensitive Prostate Cancer: Long-Term Survival Analysis of the Randomized Phase III E3805 CHAARTED Trial
- (2018) Christos E. Kyriakopoulos et al. JOURNAL OF CLINICAL ONCOLOGY
- Metabolic features of cancer stem cells: the emerging role of lipid metabolism
- (2018) Rita Mancini et al. ONCOGENE
- Targeting Mevalonate Pathway in Cancer Treatment: Repurposing of Statins
- (2018) Federica Iannelli et al. Recent Patents on Anti-Cancer Drug Discovery
- Targeting stromal remodeling and cancer stem cell plasticity overcomes chemoresistance in triple negative breast cancer
- (2018) Aurélie S. Cazet et al. Nature Communications
- Cancer Stem Cells (CSCs) in Drug Resistance and their Therapeutic Implications in Cancer Treatment
- (2018) Lan Thi Hanh Phi et al. Stem Cells International
- AICAR Antiproliferative Properties Involve the AMPK-Independent Activation of the Tumor Suppressors LATS 1 and 2
- (2018) Chloé Philippe et al. NEOPLASIA
- The regulatory pathways leading to stem-like cells underlie prostate cancer progression
- (2018) Jer-Tsong Hsieh et al. ASIAN JOURNAL OF ANDROLOGY
- Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
- (2018) Freddie Bray et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Paracrine HGF/c-MET enhances the stem cell-like potential and glycolysis of pancreatic cancer cells via activation of YAP/HIF-1α
- (2018) Bin Yan et al. EXPERIMENTAL CELL RESEARCH
- Inhibition of cholesterol biosynthesis overcomes enzalutamide resistance in castration-resistant prostate cancer (CRPC)
- (2018) Yifan Kong et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Transcriptional addiction in cancer cells is mediated by YAP/TAZ through BRD4
- (2018) Francesca Zanconato et al. NATURE MEDICINE
- Hippo signaling dysfunction induces cancer cell addiction to YAP
- (2018) Han Han et al. ONCOGENE
- Discovery of a potent HMG-CoA reductase degrader that eliminates statin-induced reductase accumulation and lowers cholesterol
- (2018) Shi-You Jiang et al. Nature Communications
- Vorinostat and Simvastatin have synergistic effects on triple-negative breast cancer cells via abrogating Rab7 prenylation
- (2017) Xinhui Kou et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- The synergistic effects of valproic acid and fluvastatin on apoptosis induction in glioblastoma multiforme cell lines
- (2017) Yung-Lung Chang et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Synergistic antitumor interaction between valproic acid, capecitabine and radiotherapy in colorectal cancer: critical role of p53
- (2017) Manuela Terranova-Barberio et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Stearoyl-CoA-desaturase 1 regulates lung cancer stemness via stabilization and nuclear localization of YAP/TAZ
- (2017) A Noto et al. ONCOGENE
- Co-Expression of Putative Cancer Stem Cell Markers CD44 and CD133 in Prostate Carcinomas
- (2017) Elham Kalantari et al. PATHOLOGY & ONCOLOGY RESEARCH
- HMG-CoA reductase promotes protein prenylation and therefore is indispensible for T-cell survival
- (2017) Sonja M Lacher et al. Cell Death & Disease
- Mevastatin blockade of autolysosome maturation stimulates LBH589-induced cell death in triple-negative breast cancer cells
- (2017) Zhaohu Lin et al. Oncotarget
- YAP1 regulates prostate cancer stem cell-like characteristics to promote castration resistant growth
- (2017) Ning Jiang et al. Oncotarget
- Phase II clinical study of valproic acid plus cisplatin and cetuximab in recurrent and/or metastatic squamous cell carcinoma of Head and Neck-V-CHANCE trial
- (2016) Francesco Caponigro et al. BMC CANCER
- Antiepileptic drugs with histone deacetylase inhibition activity and prostate cancer risk: a population-based case–control study
- (2016) Jukka K. Salminen et al. CANCER CAUSES & CONTROL
- Statin Use and Prostate Cancer Aggressiveness: Results from the Population-Based North Carolina-Louisiana Prostate Cancer Project
- (2016) E. H. Allott et al. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
- Role of the novel generation of androgen receptor pathway targeted agents in the management of castration-resistant prostate cancer: A literature based meta-analysis of randomized trials
- (2016) Giandomenico Roviello et al. EUROPEAN JOURNAL OF CANCER
- A quinazoline-based HDAC inhibitor affects gene expression pathways involved in cholesterol biosynthesis and mevalonate in prostate cancer cells
- (2016) Z. Lin et al. Molecular BioSystems
- The current evidence on statin use and prostate cancer prevention: are we there yet?
- (2016) Mahmoud A. Alfaqih et al. Nature Reviews Urology
- Control of YAP/TAZ Activity by Metabolic and Nutrient-Sensing Pathways
- (2016) Giulia Santinon et al. TRENDS IN CELL BIOLOGY
- YAP Inhibition by Resveratrol via Activation of AMPK Enhances the Sensitivity of Pancreatic Cancer Cells to Gemcitabine
- (2016) Zhengdong Jiang et al. Nutrients
- Synergistic antitumor activity of histone deacetylase inhibitors and anti-ErbB3 antibody in NSCLC primary cultures via modulation of ErbB receptors expression
- (2016) Chiara Ciardiello et al. Oncotarget
- Targeting intratumoral androgens: statins and beyond
- (2016) Michael T. Schweizer et al. Therapeutic Advances in Medical Oncology
- Dual Targeting of 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase and Histone Deacetylase as a Therapy for Colorectal Cancer
- (2016) Tzu-Tang Wei et al. EBioMedicine
- Cancer of the prostate: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up
- (2015) C. Parker et al. ANNALS OF ONCOLOGY
- Loss of histone deacetylase Hdac1 disrupts metabolic processes in intestinal epithelial cells
- (2015) Alexis Gonneaud et al. FEBS LETTERS
- The Hippo Pathway Effector YAP Regulates Motility, Invasion, and Castration-Resistant Growth of Prostate Cancer Cells
- (2015) Lin Zhang et al. MOLECULAR AND CELLULAR BIOLOGY
- MetaboAnalyst 3.0—making metabolomics more meaningful
- (2015) Jianguo Xia et al. NUCLEIC ACIDS RESEARCH
- Inhibition of the mevalonate pathway affects epigenetic regulation in cancer cells
- (2015) Heidrun Karlic et al. Cancer Genetics
- The HMG-CoA reductase inhibitor, simvastatin, exhibits anti-metastatic and anti-tumorigenic effects in ovarian cancer
- (2015) Jessica E. Stine et al. Oncotarget
- Valproic acid potentiates the anticancer activity of capecitabine in vitro and in vivo in breast cancer models via induction of thymidine phosphorylase expression
- (2015) Manuela Terranova-Barberio et al. Oncotarget
- Enrichment of the Cancer Stem Phenotype in Sphere Cultures of Prostate Cancer Cell Lines Occurs through Activation of Developmental Pathways Mediated by the Transcriptional Regulator ΔNp63α
- (2015) Roberto Portillo-Lara et al. PLoS One
- Proteomic analysis of zoledronic-acid resistant prostate cancer cells unveils novel pathways characterizing an invasive phenotype
- (2015) Milone Maria Rita et al. Oncotarget
- Phase 1/2 study of valproic acid and short-course radiotherapy plus capecitabine as preoperative treatment in low-moderate risk rectal cancer-V-shoRT-R3 (Valproic acid - short RadioTherapy - rectum 3rd trial)
- (2014) Antonio Avallone et al. BMC CANCER
- Decreased mitochondrial priming determines chemoresistance of colon cancer stem cells
- (2014) S Colak et al. CELL DEATH AND DIFFERENTIATION
- Synergistic Simvastatin and Metformin Combination Chemotherapy for Osseous Metastatic Castration-Resistant Prostate Cancer
- (2014) M. A. Babcook et al. MOLECULAR CANCER THERAPEUTICS
- Metabolic control of YAP and TAZ by the mevalonate pathway
- (2014) Giovanni Sorrentino et al. NATURE CELL BIOLOGY
- Energy Stress Regulates Hippo-YAP Signaling Involving AMPK-Mediated Regulation of Angiomotin-like 1 Protein
- (2014) Michael DeRan et al. Cell Reports
- Panobinostat synergizes with zoledronic acid in prostate cancer and multiple myeloma models by increasing ROS and modulating mevalonate and p38-MAPK pathways
- (2013) F Bruzzese et al. Cell Death & Disease
- Acquired resistance to zoledronic acid and the parallel acquisition of an aggressive phenotype are mediated by p38-MAP kinase activation in prostate cancer cells
- (2013) M R Milone et al. Cell Death & Disease
- Cholesterol and prostate cancer
- (2012) Kristine Pelton et al. CURRENT OPINION IN PHARMACOLOGY
- Mevalonate Metabolism Regulates Basal Breast Cancer Stem Cells and Is a Potential Therapeutic Target
- (2012) Christophe Ginestier et al. STEM CELLS
- Vorinostat synergises with capecitabine through upregulation of thymidine phosphorylase
- (2010) E Di Gennaro et al. BRITISH JOURNAL OF CANCER
- Romidepsin: a new therapy for cutaneous T-cell lymphoma and a potential therapy for solid tumors
- (2010) Cliona Grant et al. Expert Review of Anticancer Therapy
- The role of YAP transcription coactivator in regulating stem cell self-renewal and differentiation
- (2010) I. Lian et al. GENES & DEVELOPMENT
- Synergistic antitumor effect between vorinostat and topotecan in small cell lung cancer cells is mediated by generation of reactive oxygen species and DNA damage-induced apoptosis
- (2009) F. Bruzzese et al. MOLECULAR CANCER THERAPEUTICS
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