Enrichment of the Cancer Stem Phenotype in Sphere Cultures of Prostate Cancer Cell Lines Occurs through Activation of Developmental Pathways Mediated by the Transcriptional Regulator ΔNp63α
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Title
Enrichment of the Cancer Stem Phenotype in Sphere Cultures of Prostate Cancer Cell Lines Occurs through Activation of Developmental Pathways Mediated by the Transcriptional Regulator ΔNp63α
Authors
Keywords
DU145 cells, Gene expression, Cancer stem cells, Prostate cancer, Prostate gland, Regulator genes, Gene ontologies, Transcriptional control
Journal
PLoS One
Volume 10, Issue 6, Pages e0130118
Publisher
Public Library of Science (PLoS)
Online
2015-06-26
DOI
10.1371/journal.pone.0130118
References
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Note: Only part of the references are listed.- Regulators of prostate cancer stem cells
- (2014) Candace L. Kerr et al. CURRENT OPINION IN ONCOLOGY
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- (2013) Lei Wang et al. International Journal of Biological Sciences
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- (2013) J.-C. Pignon et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2012) Brian D. Kelly et al. BJU INTERNATIONAL
- CD133 as a biomarker for putative cancer stem cells in solid tumours: limitations, problems and challenges
- (2012) Philipp Grosse-Gehling et al. JOURNAL OF PATHOLOGY
- PDGF enhances IRES-mediated translation of Laminin B1 by cytoplasmic accumulation of La during epithelial to mesenchymal transition
- (2012) Michaela Petz et al. NUCLEIC ACIDS RESEARCH
- The ConsensusPathDB interaction database: 2013 update
- (2012) Atanas Kamburov et al. NUCLEIC ACIDS RESEARCH
- Characterization of Peptide Aptamers Targeting Bfl-1 Anti-Apoptotic Protein
- (2011) G. Brien et al. BIOCHEMISTRY
- IGFBP-3 Is a Metastasis Suppression Gene in Prostate Cancer
- (2011) H. H. Mehta et al. CANCER RESEARCH
- BCL2A1: the underdog in the BCL2 family
- (2011) M Vogler CELL DEATH AND DIFFERENTIATION
- ΔNp63α Protein Triggers Epithelial-Mesenchymal Transition and Confers Stem Cell Properties in Normal Human Keratinocytes
- (2011) Ju-Eun Oh et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Implication of platelet-derived growth factor receptor alpha in prostate cancer skeletal metastasis
- (2011) Qingxin Liu et al. Chinese Journal of Cancer
- Genomic profiling of tumor initiating prostatospheres
- (2010) Maria Duhagon et al. BMC GENOMICS
- Overexpression of ΔNp63α induces a stem cell phenotype in MCF7 breast carcinoma cell line through the Notch pathway
- (2010) Zhijian Du et al. CANCER SCIENCE
- Targeting the Receptor for Platelet-Derived Growth Factor as a Primary or Combination Therapy in a Preclinical Model of Prostate Cancer Skeletal Metastasis
- (2010) M. R. Russell et al. CLINICAL CANCER RESEARCH
- Expectations, validity, and reality in gene expression profiling
- (2010) Kyoungmi Kim et al. JOURNAL OF CLINICAL EPIDEMIOLOGY
- ΔNp63 transcriptionally regulates ATM to control p53 Serine-15 phosphorylation
- (2010) Ashley L Craig et al. Molecular Cancer
- Effective enrichment of prostate cancer stem cells from spheres in a suspension culture system
- (2010) Xinlan Fan et al. UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS
- GeneCards Version 3: the human gene integrator
- (2010) M. Safran et al. Database-The Journal of Biological Databases and Curation
- Profiling Cancer Stem Cells in Androgen-Responsive and Refractory Human Prostate Tumor Cell Lines
- (2009) Letizia Cocciadiferro et al. Annals of the New York Academy of Sciences
- Stem Cell Characteristics in Prostate Cancer Cell Lines
- (2009) Minja J. Pfeiffer et al. EUROPEAN UROLOGY
- Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
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- Direct multiplexed measurement of gene expression with color-coded probe pairs
- (2008) Gary K Geiss et al. NATURE BIOTECHNOLOGY
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