The role of TRPV1 ion channels in the suppression of gastric cancer development

Plasma membrane Ca2+-permeable channels and sodium/calcium exchangers in tumorigenesis and tumor development of the upper gastrointestinal tract

(2020) JianHong Ding et al.   CANCER LETTERS

SNCG promotes the progression and metastasis of high-grade serous ovarian cancer via targeting the PI3K/AKT signaling pathway

(2020) Jing Zhang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

VPAC1 couples with TRPV4 channel to promote calcium-dependent gastric cancer progression via a novel autocrine mechanism

(2019) Bo Tang et al.   ONCOGENE

Immunomodulatory effect of oleoylethanolamide in dendritic cells via TRPV1/AMPK activation

(2019) Enhui Yao et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Sinomenine exerts antitumour effect in gastric cancer cells via enhancement of miR‐204 expression

(2019) Haifeng Yuan et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

TRPV6 calcium channel regulation, downstream pathways, and therapeutic targeting in cancer

(2019) Aurélien Haustrate et al.   CELL CALCIUM

Capsaicinoids: Multiple effects on angiogenesis, invasion and metastasis in human cancers

(2019) Jamie R. Friedman et al.   BIOMEDICINE & PHARMACOTHERAPY

Role of ion channels in gastrointestinal cancer

(2019) Kyle J Anderson et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Pyrazolo[1,5-a]pyrimidine TRPC6 antagonists for the treatment of gastric cancer

(2018) Mingmin Ding et al.   CANCER LETTERS

Copper sulfide nanoparticles as a photothermal switch for TRPV1 signaling to attenuate atherosclerosis

(2018) Wen Gao et al.   Nature Communications

Capsaicin inhibits the metastasis of human papillary thyroid carcinoma BCPAP cells through the modulation of the TRPV1 channel

(2018) Shichen Xu et al.   Food & Function

Management of Metastatic Gastric Cancer

(2017) Radka Obermannová et al.   HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA

Hedgehog signaling pathway as a potential target in the treatment of advanced gastric cancer

(2017) Dae-Hee Lee et al.   TUMOR BIOLOGY

Loss of E-Cadherin-Dependent Cell–Cell Adhesion and the Development and Progression of Cancer

(2017) Heather C. Bruner et al.   Cold Spring Harbor Perspectives in Biology

TRPM5 mediates acidic extracellular pH signaling and TRPM5 inhibition reduces spontaneous metastasis in mouse B16-BL6 melanoma cells

(2017) Toyonobu Maeda et al.   Oncotarget

AMPKα phosphatase Ppm1E upregulation in human gastric cancer is required for cell proliferation

(2017) Min-Bin Chen et al.   Oncotarget

TRPV1 Regulates Stress Responses through HDAC2

(2017) Sung Eun Wang et al.   Cell Reports

Understand spiciness: mechanism of TRPV1 channel activation by capsaicin

(2017) Fan Yang et al.   Protein & Cell

Targeting calcium signaling in cancer therapy

(2017) Chaochu Cui et al.   Acta Pharmaceutica Sinica B

IP3 Receptor-Mediated Calcium Signaling and Its Role in Autophagy in Cancer

(2017) Elzbieta Kania et al.   Frontiers in Oncology

Elevated Orai1 and STIM1 expressions upregulate MACC1 expression to promote tumor cell proliferation, metabolism, migration, and invasion in human gastric cancer

(2016) Jianling Xia et al.   CANCER LETTERS

Cell cycle proliferation decisions: the impact of single cell analyses

(2016) Jacob P. Matson et al.   FEBS Journal

Distinct TRPV1- and TRPA1-based mechanisms underlying enhancement of oral ulcerative mucositis-induced pain by 5-fluorouracil

(2016) Kiichiro Yamaguchi et al.   PAIN

The Ca 2+ /Calmodulin/CaMKK2 Axis: Nature's Metabolic CaMshaft

(2016) Kathrina L. Marcelo et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

The AMP-activated protein kinase (AMPK) and cancer: Many faces of a metabolic regulator

(2015) Brandon Faubert et al.   CANCER LETTERS

Role of the LKB1/AMPK pathway in tumor invasion and metastasis of cancer cells (Review)

(2015) NIANSHUANG LI et al.   ONCOLOGY REPORTS

Anticancer effect of adenosine on gastric cancerviadiverse signaling pathways

(2015) Ayako Tsuchiya   WORLD JOURNAL OF GASTROENTEROLOGY

Capsaicin induces apoptosis in human small cell lung cancer via the TRPV6 receptor and the calpain pathway

(2014) Jamie K. Lau et al.   APOPTOSIS

Can calcium signaling be harnessed for cancer immunotherapy?

(2014) Ronald Rooke   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Relationships Between Abnormal MMP2 Expression and Prognosis in Gastric Cancer: A Meta-Analysis of Cohort Studies

(2014) He-Ling Wang et al.   CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS

Gastric Cancer: Descriptive Epidemiology, Risk Factors, Screening, and Prevention

(2014) P. Karimi et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

MicroRNA and signaling pathways in gastric cancer

(2014) Z Zhang et al.   CANCER GENE THERAPY

Attenuation of natural killer cell functions by capsaicin through a direct and TRPV1-independent mechanism

(2014) Hun Sik Kim et al.   CARCINOGENESIS

HNF4α is a therapeutic target that links AMPK to WNT signalling in early-stage gastric cancer

(2014) Hae Ryung Chang et al.   GUT

Ion channel TRPV1-dependent activation of PTP1B suppresses EGFR-associated intestinal tumorigenesis

(2014) Petrus R. de Jong et al.   JOURNAL OF CLINICAL INVESTIGATION

The ion channel TRPV1 regulates the activation and proinflammatory properties of CD4+ T cells

(2014) Samuel Bertin et al.   NATURE IMMUNOLOGY

TRPV1 Channels: Not So Inactive on the ER

(2014) Elliot Imler et al.   NEURON

TRPV1 activation impedes foam cell formation by inducing autophagy in oxLDL-treated vascular smooth muscle cells

(2014) B-H Li et al.   Cell Death & Disease

Bladder Cancer and Urothelial Impairment: The Role of TRPV1 as Potential Drug Target

(2014) Francesco Mistretta et al.   Biomed Research International

Cold stress accentuates pressure overload-induced cardiac hypertrophy and contractile dysfunction: Role of TRPV1/AMPK-mediated autophagy

(2013) Songhe Lu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

New insights into pharmacological tools to TR(i)P cancer up

(2013) M Gautier et al.   BRITISH JOURNAL OF PHARMACOLOGY

Functionally Important Amino Acid Residues in the Transient Receptor Potential Vanilloid 1 (TRPV1) Ion Channel - An Overview of the Current Mutational Data

(2013) Zoltán Winter et al.   Molecular Pain

Tumour heterogeneity and cancer cell plasticity

(2013) Corbin E. Meacham et al.   NATURE

Involvement of melastatin type transient receptor potential 7 channels in ginsenoside Rd-induced apoptosis in gastric and breast cancer cells

(2013) Byung Joo Kim   Journal of Ginseng Research

Vanilloid Receptor-1 Regulates Neurogenic Inflammation in Colon and Protects Mice from Colon Cancer

(2012) A. G. Vinuesa et al.   CANCER RESEARCH

Calcium Channels and Pumps in Cancer: Changes and Consequences

(2012) Gregory R. Monteith et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Transient receptor potential vanilloid 1 activation induces autophagy in thymocytes through ROS-regulated AMPK and Atg4C pathways

(2012) V. Farfariello et al.   JOURNAL OF LEUKOCYTE BIOLOGY

TRP Channels and Cancer: New Targets for Diagnosis and Chemotherapy

(2012) Giorgio Santoni et al.   Endocrine Metabolic & Immune Disorders-Drug Targets

Blockade of TRPC6 channels induced G2/M phase arrest and suppressed growth in human gastric cancer cells

(2009) Rong Cai et al.   INTERNATIONAL JOURNAL OF CANCER

Assessment of “grading” with Ki-67 and c-kit immunohistochemical expressions may be a helpful tool in management of patients with flat epithelial atypia (FEA) and columnar cell lesions (CCLs) on core breast biopsy

(2009) Rosa M. Tomasino et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Expression of retinoblastoma and cyclin D1 in gastric carcinoma

(2009) D. Arici et al.   NEOPLASMA