A lever-like transduction pathway for long-distance chemical- and mechano-gating of the mechanosensitive Piezo1 channel
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Title
A lever-like transduction pathway for long-distance chemical- and mechano-gating of the mechanosensitive Piezo1 channel
Authors
Keywords
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Journal
Nature Communications
Volume 9, Issue 1, Pages -
Publisher
Springer Nature
Online
2018-04-04
DOI
10.1038/s41467-018-03570-9
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Related references
Note: Only part of the references are listed.- Structure and mechanogating mechanism of the Piezo1 channel
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- The mechanosensitive Piezo1 channel: structural features and molecular bases underlying its ion permeation and mechanotransduction
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- Endothelial cation channel PIEZO1 controls blood pressure by mediating flow-induced ATP release
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- Piezo1 Channels Are Inherently Mechanosensitive
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- Architecture of the mammalian mechanosensitive Piezo1 channel
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- Piezo2 is the principal mechanotransduction channel for proprioception
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- Mechanically Activated Ion Channels
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- Impaired PIEZO1 function in patients with a novel autosomal recessive congenital lymphatic dysplasia
- (2015) Viktor Lukacs et al. Nature Communications
- Novel mutations in PIEZO1 cause an autosomal recessive generalized lymphatic dysplasia with non-immune hydrops fetalis
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- Piezo1 in Smooth Muscle Cells Is Involved in Hypertension-Dependent Arterial Remodeling
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- Chemical activation of the mechanotransduction channel Piezo1
- (2015) Ruhma Syeda et al. eLife
- Mutations in PIEZO2 Cause Gordon Syndrome, Marden-Walker Syndrome, and Distal Arthrogryposis Type 5
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- Merkel Cells Transduce and Encode Tactile Stimuli to Drive Aβ-Afferent Impulses
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- Epidermal Merkel cells are mechanosensory cells that tune mammalian touch receptors
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- Piezo2 is required for Merkel-cell mechanotransduction
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- Piezo1 integration of vascular architecture with physiological force
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- Stochastic nanoroughness modulates neuron–astrocyte interactions and function via mechanosensing cation channels
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- Stretch-activated ion channel Piezo1 directs lineage choice in human neural stem cells
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- Piezo1, a mechanically activated ion channel, is required for vascular development in mice
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- Feeling the hidden mechanical forces in lipid bilayer is an original sense
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- Ultrasensitive fluorescent proteins for imaging neuronal activity
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- Gain-of-function mutations in the mechanically activated ion channel PIEZO2 cause a subtype of Distal Arthrogryposis
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- Xerocytosis is caused by mutations that alter the kinetics of the mechanosensitive channel PIEZO1
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- Mutations in the mechanotransduction protein PIEZO1 are associated with hereditary xerocytosis
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- Piezo proteins are pore-forming subunits of mechanically activated channels
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- Loss of the Integrin-Activating Transmembrane Protein Fam38A (Piezo1) Promotes a Switch to a Reduced Integrin-Dependent Mode of Cell Migration
- (2012) Brian J. McHugh et al. PLoS One
- Temperature-dependent STIM1 activation induces Ca2+ influx and modulates gene expression
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- Mechanosensitive Channels in Microbes
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- Piezo1 and Piezo2 Are Essential Components of Distinct Mechanically Activated Cation Channels
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- Neurosensory mechanotransduction
- (2008) Martin Chalfie NATURE REVIEWS MOLECULAR CELL BIOLOGY
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