Canonical Notch ligands and Fringes have distinct effects on NOTCH1 and NOTCH2

Protein O-glucosylation: another essential role of glucose in biology

(2019) Hongjun Yu et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Structure and function of extracellular O-GlcNAc

(2019) Mitsutaka Ogawa et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Protein O-fucosylation: structure and function

(2019) Bernadette C Holdener et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

A modifier in the 129S2/SvPasCrl genome is responsible for the viability of Notch1[12f/12f] mice

(2019) Shweta Varshney et al.   BMC DEVELOPMENTAL BIOLOGY

Glycosylation of Specific Notch EGF Repeats by O-Fut1 and Fringe Regulates Notch Signaling in Drosophila

(2019) Ashutosh Pandey et al.   Cell Reports

Multiple Roles for O-Glycans in Notch Signalling

(2018) Shweta Varshney et al.   FEBS LETTERS

Manic Fringe deficiency imposes Jagged1 addiction to intestinal tumor cells

(2018) Erika López-Arribillaga et al.   Nature Communications

The PRIDE database and related tools and resources in 2019: improving support for quantification data

(2018) Yasset Perez-Riverol et al.   NUCLEIC ACIDS RESEARCH

The ectodomains determine ligand function in vivo and selectivity of DLL1 and DLL4 toward NOTCH1 and NOTCH2 in vitro

(2018) Lena Tveriakhina et al.   eLife

O-Glycosylation modulates the stability of epidermal growth factor-like repeats and thereby regulates Notch trafficking

(2017) Hideyuki Takeuchi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Notch-Jagged complex structure implicates a catch bond in tuning ligand sensitivity

(2017) Vincent C. Luca et al.   SCIENCE

Mapping Sites ofO-Glycosylation and Fringe Elongation onDrosophilaNotch

(2016) Beth M. Harvey et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Notch signalling in context

(2016) Sarah J. Bray   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The many roles of Notch signaling during vertebrate somitogenesis

(2016) Kanu Wahi et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Manic Fringe Promotes a Claudin-Low Breast Cancer Phenotype through Notch-Mediated PIK3CG Induction

(2015) S. Zhang et al.   CANCER RESEARCH

The multiple roles of epidermal growth factor repeatO-glycans in animal development

(2015) Amanda R Haltom et al.   GLYCOBIOLOGY

Jagged1 heterozygosity in mice results in a congenital cholangiopathy which is reversed by concomitant deletion of one copy ofPoglut1(Rumi)

(2015) Shakeel M. Thakurdas et al.   HEPATOLOGY

Lunatic, Manic, and Radical Fringe Each Promote T and B Cell Development

(2015) Yinghui Song et al.   JOURNAL OF IMMUNOLOGY

Sequential Notch activation regulates ventricular chamber development

(2015) Gaetano D’Amato et al.   NATURE CELL BIOLOGY

Structural basis for Notch1 engagement of Delta-like 4

(2015) V. C. Luca et al.   SCIENCE

Mutations in NOTCH1 Cause Adams-Oliver Syndrome

(2014) Anna-Barbara Stittrich et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Fringe-mediated extension of O-linked fucose in the ligand-binding region of Notch1 increases binding to mammalian Notch ligands

(2014) P. Taylor et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fringe proteins modulate Notch-ligand cis and trans interactions to specify signaling states

(2014) Lauren LeBon et al.   eLife

The Extracellular Domain of Notch2 Increases Its Cell-Surface Abundance and Ligand Responsiveness during Kidney Development

(2013) Zhenyi Liu et al.   DEVELOPMENTAL CELL

Intrinsic Selectivity of Notch 1 for Delta-like 4 Over Delta-like 1

(2013) Marie Blanke Andrawes et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lunatic Fringe Deficiency Cooperates with the Met/Caveolin Gene Amplicon to Induce Basal-like Breast Cancer

(2012) Keli Xu et al.   CANCER CELL

Fringe benefits: Functional and structural impacts of O-glycosylation on the extracellular domain of Notch receptors

(2011) Nadia A Rana et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Mutations in NOTCH2 cause Hajdu-Cheney syndrome, a disorder of severe and progressive bone loss

(2011) Michael A Simpson et al.   NATURE GENETICS

The Notch Ligands Dll4 and Jagged1 Have Opposing Effects on Angiogenesis

(2009) Rui Benedito et al.   CELL

The Canonical Notch Signaling Pathway: Unfolding the Activation Mechanism

(2009) Raphael Kopan et al.   CELL

Manic fringe is not required for embryonic development, and fringe family members do not exhibit redundant functions in the axial skeleton, limb, or hindbrain

(2009) Jennifer L. Moran et al.   DEVELOPMENTAL DYNAMICS

Regulation of Notch signaling during T- and B-cell development byO-fucose glycans

(2009) Pamela Stanley et al.   IMMUNOLOGICAL REVIEWS

Bile duct proliferation in Jag1/fringe heterozygous mice identifies candidate modifiers of the alagille syndrome hepatic phenotype

(2008) Matthew J. Ryan et al.   HEPATOLOGY