STIM1 Deficiency Leads to Specific Down-Regulation of ITPR3 in SH-SY5Y Cells

RAC1-Dependent ORAI1 Translocation to the Leading Edge Supports Lamellipodia Formation and Directional Persistence

(2020) Aida M. Lopez-Guerrero et al.   Scientific Reports

Type 3 inositol 1,4,5-trisphosphate receptor has antiapoptotic and proliferative role in cancer cells

(2019) Ingeborg Rezuchova et al.   Cell Death & Disease

STIM Proteins and Glutamate Receptors in Neurons: Role in Neuronal Physiology and Neurodegenerative Diseases

(2019) Karolina Serwach et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Type 3 inositol 1,4,5‐trisphosphate receptor is increased and enhances malignant properties in cholangiocarcinoma

(2019) Pimwipa Ueasilamongkol et al.   HEPATOLOGY

Synaptic crosstalk conferred by a zone of differentially regulated Ca2+ signaling in the dendritic shaft adjoining a potentiated spine

(2019) Philip J. Dittmer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Store-Operated Calcium Channels: From Function to Structure and Back Again

(2019) Richard S. Lewis   Cold Spring Harbor Perspectives in Biology

IP3 receptor isoforms differently regulate ER-mitochondrial contacts and local calcium transfer

(2019) Adam Bartok et al.   Nature Communications

Molecular Tuning of the Axonal Mitochondrial Ca2+ Uniporter Ensures Metabolic Flexibility of Neurotransmission

(2019) Ghazaleh Ashrafi et al.   NEURON

DYSREGULATION OF INTRACELLULAR CALCIUM SIGNALING IN ALZHEIMER’S DISEASE

(2018) Elena Popugaeva et al.   ANTIOXIDANTS & REDOX SIGNALING

The store-operated calcium channels in cancer metastasis from cell migration invasion to metastatic colonization

(2018) Shengyu Yang   Frontiers in Bioscience-Landmark

Calcium signaling in Alzheimer's disease & therapies

(2018) Benjamin Chun-Kit Tong et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

STIM1 deficiency is linked to Alzheimer’s disease and triggers cell death in SH-SY5Y cells by upregulation of L-type voltage-operated Ca2+ entry

(2018) Carlos Pascual-Caro et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Calcium, mitochondrial dysfunction and slowing the progression of Parkinson's disease

(2017) D. James Surmeier et al.   EXPERIMENTAL NEUROLOGY

INF2-mediated actin polymerization at the ER stimulates mitochondrial calcium uptake, inner membrane constriction, and division

(2017) Rajarshi Chakrabarti et al.   JOURNAL OF CELL BIOLOGY

STIM1 Regulates Somatic Ca 2+ Signals and Intrinsic Firing Properties of Cerebellar Purkinje Neurons

(2017) Changhyeon Ryu et al.   JOURNAL OF NEUROSCIENCE

Axonal Endoplasmic Reticulum Ca 2+ Content Controls Release Probability in CNS Nerve Terminals

(2017) Jaime de Juan-Sanz et al.   NEURON

Downregulation of type 3 inositol (1,4,5)-trisphosphate receptor decreases breast cancer cell migration through an oscillatory Ca2+ signal

(2017) Abdallah Mound et al.   Oncotarget

STIM1 Ca 2+ Sensor Control of L-type Ca 2+ -Channel-Dependent Dendritic Spine Structural Plasticity and Nuclear Signaling

(2017) Philip J. Dittmer et al.   Cell Reports

STIM and ORAI proteins: crucial roles in hallmarks of cancer

(2016) A. Fiorio Pla et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Molecular mechanisms of STIM/Orai communication

(2016) Isabella Derler et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Familial Alzheimer’s disease–associated presenilin 1 mutants promote γ-secretase cleavage of STIM1 to impair store-operated Ca2+entry

(2016) Benjamin Chun-Kit Tong et al.   Science Signaling

AMPA Receptors Are Involved in Store-Operated Calcium Entry and Interact with STIM Proteins in Rat Primary Cortical Neurons

(2016) Joanna Gruszczynska-Biegala et al.   Frontiers in Cellular Neuroscience

Selective Vulnerability of Cancer Cells by Inhibition of Ca2+ Transfer from Endoplasmic Reticulum to Mitochondria

(2016) César Cárdenas et al.   Cell Reports

Familial Alzheimer’s disease–associated presenilin 1 mutants promote γ-secretase cleavage of STIM1 to impair store-operated Ca2+entry

(2016) Benjamin Chun-Kit Tong et al.   Science Signaling

Diseases caused by mutations inORAI1andSTIM1

(2015) Rodrigo S. Lacruz et al.   Annals of the New York Academy of Sciences

The regulation of neuronal mitochondrial metabolism by calcium

(2015) I. Llorente-Folch et al.   JOURNAL OF PHYSIOLOGY-LONDON

Impaired spatial memory and enhanced long-term potentiation in mice with forebrain-specific ablation of the Stim genes

(2015) Gisela Garcia-Alvarez et al.   Frontiers in Behavioral Neuroscience

Inositol 1,4,5-trisphosphate receptor-isoform diversity in cell death and survival

(2014) Hristina Ivanova et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Familial Alzheimer’s disease–associated presenilin-1 alters cerebellar activity and calcium homeostasis

(2014) Diego Sepulveda-Falla et al.   JOURNAL OF CLINICAL INVESTIGATION

Reduced Synaptic STIM2 Expression and Impaired Store-Operated Calcium Entry Cause Destabilization of Mature Spines in Mutant Presenilin Mice

(2014) Suya Sun et al.   NEURON

STIM1, a direct target of microRNA-185, promotes tumor metastasis and is associated with poor prognosis in colorectal cancer

(2014) Z Zhang et al.   ONCOGENE

STIM1 overexpression promotes colorectal cancer progression, cell motility and COX-2 expression

(2014) J-Y Wang et al.   ONCOGENE

Inhibition of STIM1 phosphorylation underlies resveratrol-induced inhibition of store-operated calcium entry

(2013) Vanessa Casas-Rua et al.   BIOCHEMICAL PHARMACOLOGY

STIM1 participates in the contractile rhythmicity of HL-1 cells by moderating T-type Ca2+ channel activity

(2013) Nathalie Nguyen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Phosphorylation of STIM1 at ERK1/2 target sites regulates interaction with the microtubule plus-end binding protein EB1

(2013) E. Pozo-Guisado et al.   JOURNAL OF CELL SCIENCE

Dimers of mitochondrial ATP synthase form the permeability transition pore

(2013) V. Giorgio et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Upregulated function of mitochondria-associated ER membranes in Alzheimer disease

(2012) Estela Area-Gomez et al.   EMBO JOURNAL

Calcium signaling around Mitochondria Associated Membranes (MAMs)

(2011) Simone Patergnani et al.   Cell Communication and Signaling

VDAC1 selectively transfers apoptotic Ca2+ signals to mitochondria

(2011) D De Stefani et al.   CELL DEATH AND DIFFERENTIATION

Essential Regulation of Cell Bioenergetics by Constitutive InsP3 Receptor Ca2+ Transfer to Mitochondria

(2010) César Cárdenas et al.   CELL

The type III inositol 1,4,5-trisphosphate receptor is associated with aggressiveness of colorectal carcinoma

(2010) Kazunori Shibao et al.   CELL CALCIUM

The CRAC Channel Activator STIM1 Binds and Inhibits L-Type Voltage-Gated Calcium Channels

(2010) C. Y. Park et al.   SCIENCE

The Calcium Store Sensor, STIM1, Reciprocally Controls Orai and CaV1.2 Channels

(2010) Y. Wang et al.   SCIENCE

Activation of STIM1-Orai1 Involves an Intramolecular Switching Mechanism

(2010) M. K. Korzeniowski et al.   Science Signaling

Presenilins Are Enriched in Endoplasmic Reticulum Membranes Associated with Mitochondria

(2009) Estela Area-Gomez et al.   AMERICAN JOURNAL OF PATHOLOGY

Mitochondrial calcium and the permeability transition in cell death

(2009) John J. Lemasters et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Ca2+ transfer from the ER to mitochondria: When, how and why

(2009) Rosario Rizzuto et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Biophysical characterization of the EF-hand and SAM domain containing Ca2+ sensory region of STIM1 and STIM2

(2008) Le Zheng et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Presenilin-dependent expression of STIM proteins and dysregulation of capacitative Ca2+ entry in familial Alzheimer's disease

(2008) Lukasz Bojarski et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH