Advances in Oligonucleotide Aptamers for NSCLC Targeting

Aptamers as Versatile Ligands for Biomedical and Pharmaceutical Applications

(2020) Baozhang Guan et al.   International Journal of Nanomedicine

Aptamers, the Nucleic Acid Antibodies, in Cancer Therapy

(2020) Zhaoying Fu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Aptamers in Non-Small Cell Lung Cancer Treatment

(2020) Irena Wieleba et al.   MOLECULES

Targeted delivery of Rab26 siRNA with precisely tailored DNA prism for lung cancer therapy

(2019) Qian Liu et al.   CHEMBIOCHEM

Development of DNA Aptamers to Native EpCAM for Isolation of Lung Circulating Tumor Cells from Human Blood

(2019) Galina Zamay et al.   Cancers

Codelivery of Genistein and miRNA-29b to A549 Cells Using Aptamer-Hybrid Nanoparticle Bioconjugates

(2019) Koita Sacko et al.   Nanomaterials

PD-L1 Expression with Epithelial Mesenchymal Transition of Circulating Tumor Cells Is Associated with Poor Survival in Curatively Resected Non-Small Cell Lung Cancer

(2019) Yariswamy Manjunath et al.   Cancers

Selective eradication of human non-small cell lung cancer cells using aptamer-decorated nanoparticles harboring a cytotoxic drug cargo

(2019) Shira Engelberg et al.   Cell Death & Disease

Axl-Targeted Delivery of the Oncosuppressor miR-137 in Non-small-Cell Lung Cancer

(2019) Silvia Nuzzo et al.   Molecular Therapy-Nucleic Acids

Dual‑targeting nanomicelles with CD133 and CD44 aptamers for enhanced delivery of gefitinib to two populations of lung cancer‑initiating cells

(2019) Xiaolong Huang et al.   Experimental and Therapeutic Medicine

Characterization of A Bifunctional Synthetic RNA Aptamer and A Truncated Form for Ability to Inhibit Growth of Non-Small Cell Lung Cancer

(2019) Hanlu Wang et al.   Scientific Reports

Chloroquine in combination with aptamer-modified nanocomplexes for tumor vessel normalization and efficient erlotinib/Survivin shRNA co-delivery to overcome drug resistance in EGFR-mutated non-small cell lung cancer

(2018) Tingting Lv et al.   Acta Biomaterialia

Evaluation of MUC1-Aptamer Functionalized Hybrid Nanoparticles for Targeted Delivery of miRNA-29b to Nonsmall Cell Lung Cancer

(2018) Maryna Perepelyuk et al.   MOLECULAR PHARMACEUTICS

Ultrasensitive and high specific detection of non-small-cell lung cancer cells in human serum and clinical pleural effusion by aptamer-based fluorescence spectroscopy

(2018) Yuhang Wu et al.   TALANTA

TEMPORARY REMOVAL: MAFG is a potential therapeutic target to restore chemosensitivity in cisplatin-resistant cancer cells by increasing reactive oxygen species

(2018) Olga Vera-Puente et al.   Translational Research

Cancer cell-selective, clathrin-mediated endocytosis of aptamerdecorated nanoparticles

(2018) Shira Engelberg et al.   Oncotarget

In Vivo SELEX of an Inhibitory NSCLC-Specific RNA Aptamer from PEGylated RNA Library

(2018) Hanlu Wang et al.   Molecular Therapy-Nucleic Acids

Current Advances in Aptamers for Cancer Diagnosis and Therapy

(2018) Shin-ichiro Hori et al.   Cancers

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Aptamer-miR-34c conjugate affects cell proliferation of non-small cell lung cancer cells

(2018) Valentina Russo et al.   Molecular Therapy-Nucleic Acids

Lung Cancers: Molecular Characterization, Clonal Heterogeneity and Evolution, and Cancer Stem Cells

(2018) Ugo Testa et al.   Cancers

In vivo SELEX of bone targeting aptamer in prostate cancer bone metastasis model

(2018) Lingxiao Chen et al.   International Journal of Nanomedicine

A Microwell-Assisted Multiaptamer Immunomagnetic Platform for Capture and Genetic Analysis of Circulating Tumor Cells

(2018) Zaizai Dong et al.   Advanced Healthcare Materials

Aptamer-targeted delivery of Bcl-xL shRNA using alkyl modified PAMAM dendrimers into lung cancer cells

(2017) Sara Ayatollahi et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Recent Advances in SELEX Technology and Aptamer Applications in Biomedicine

(2017) Zhenjian Zhuo et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

An aptamer for recognizing the transmembrane protein PDL-1 (programmed death-ligand 1), and its application to fluorometric single cell detection of human ovarian carcinoma cells

(2017) Rezvan Yazdian-Robati et al.   MICROCHIMICA ACTA

Current approaches for avoiding the limitations of circulating tumor cells detection methods—implications for diagnosis and treatment of patients with solid tumors

(2017) Artur Kowalik et al.   Translational Research

A Combined PD-1/C5a Blockade Synergistically Protects against Lung Cancer Growth and Metastasis

(2017) Daniel Ajona et al.   Cancer Discovery

DNA Aptamers for the Characterization of Histological Structure of Lung Adenocarcinoma

(2017) Galina S. Zamay et al.   Molecular Therapy-Nucleic Acids

Aptamer-hybrid nanoparticle bioconjugate efficiently delivers miRNA-29b to non-small-cell lung cancer cells and inhibits growth by downregulating essential oncoproteins

(2016) Sunday Shoyele et al.   International Journal of Nanomedicine

Pre-existing anti-PEG antibodies are associated with severe immediate allergic reactions to pegnivacogin, a PEGylated aptamer

(2016) Thomas J. Povsic et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Pre-existing anti–polyethylene glycol antibody linked to first-exposure allergic reactions to pegnivacogin, a PEGylated RNA aptamer

(2016) Nancy J. Ganson et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

An aptamer-antibody complex (oligobody) as a novel delivery platform for targeted cancer therapies

(2016) Kyun Heo et al.   JOURNAL OF CONTROLLED RELEASE

AS1411 Aptamer-Decorated Biodegradable Polyethylene Glycol–Poly(lactic-co-glycolic acid) Nanopolymersomes for the Targeted Delivery of Gemcitabine to Non–Small Cell Lung Cancer In Vitro

(2016) Mona Alibolandi et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Scientific Advances in Lung Cancer 2015

(2016) Anne S. Tsao et al.   Journal of Thoracic Oncology

Aptamers as targeted therapeutics: current potential and challenges

(2016) Jiehua Zhou et al.   NATURE REVIEWS DRUG DISCOVERY

Enhanced and Differential Capture of Circulating Tumor Cells from Lung Cancer Patients by Microfluidic Assays Using Aptamer Cocktail

(2016) Libo Zhao et al.   Small

Aptamer-miRNA-212 Conjugate Sensitizes NSCLC Cells to TRAIL

(2016) Margherita Iaboni et al.   Molecular Therapy-Nucleic Acids

A Novel PD-L1-targeting Antagonistic DNA Aptamer With Antitumor Effects

(2016) Wei-Yun Lai et al.   Molecular Therapy-Nucleic Acids

A recognition-before-labeling strategy for sensitive detection of lung cancer cells with a quantum dot–aptamer complex

(2015) Chunlei Wu et al.   ANALYST

Ultrasensitive cytosensing based on an aptamer modified nanobiosensor with a bioconjugate: Detection of human non-small-cell lung cancer cells

(2015) Tanveer A. Mir et al.   BIOSENSORS & BIOELECTRONICS

Cellular delivery of shRNA using aptamer-conjugated PLL-alkyl-PEI nanoparticles

(2015) Saeedeh Askarian et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Epithelial cell adhesion molecule aptamer conjugated PEG–PLGA nanopolymersomes for targeted delivery of doxorubicin to human breast adenocarcinoma cell line in vitro

(2015) Mona Alibolandi et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

In vitro and in vivo evaluation of therapy targeting epithelial-cell adhesion-molecule aptamers for non-small cell lung cancer

(2015) Mona Alibolandi et al.   JOURNAL OF CONTROLLED RELEASE

Mechanistic studies of anticancer aptamer AS1411 reveal a novel role for nucleolin in regulating Rac1 activation

(2015) E. Merit Reyes-Reyes et al.   Molecular Oncology

Aptamers Selected to Postoperative Lung Adenocarcinoma Detect Circulating Tumor Cells in Human Blood

(2015) Galina S Zamay et al.   MOLECULAR THERAPY

Capturing Cancer: Emerging Microfluidic Technologies for the Capture and Characterization of Circulating Tumor Cells

(2015) Weiyi Qian et al.   Small

Targeting the PD-1/PD-L1 Immune Evasion Axis With DNA Aptamers as a Novel Therapeutic Strategy for the Treatment of Disseminated Cancers

(2015) Aaron Prodeus et al.   Molecular Therapy-Nucleic Acids

Aptamer-Dendrimer Bioconjugates for Targeted Delivery of miR-34a Expressing Plasmid and Antitumor Effects in Non-Small Cell Lung Cancer Cells

(2015) Hongmei Wang et al.   PLoS One

Methuosis

(2014) William A. Maltese et al.   AMERICAN JOURNAL OF PATHOLOGY

Synergistic inhibition of lung cancer cell invasion, tumor growth and angiogenesis using aptamer-siRNA chimeras

(2014) Wei-Yun Lai et al.   BIOMATERIALS

Multifunctional Aptamer-miRNA Conjugates for Targeted Cancer Therapy

(2014) Carla L Esposito et al.   MOLECULAR THERAPY

DNA-Aptamer Targeting Vimentin for Tumor Therapy In Vivo

(2014) Tatyana N. Zamay et al.   Nucleic Acid Therapeutics

Oligonucleotide Aptamers: New Tools for Targeted Cancer Therapy

(2014) Hongguang Sun et al.   Molecular Therapy-Nucleic Acids

DNA aptamers that target human glioblastoma multiforme cells overexpressing epidermal growth factor receptor variant III in vitro

(2013) Yan Tan et al.   ACTA PHARMACOLOGICA SINICA

Specific Capture and Release of Circulating Tumor Cells Using Aptamer-Modified Nanosubstrates

(2013) Qinglin Shen et al.   ADVANCED MATERIALS

MiRNA-29: A microRNA Family with Tumor-Suppressing and Immune-Modulating Properties

(2013) M.J. Schmitt et al.   CURRENT MOLECULAR MEDICINE

Identification of CD90 as a marker for lung cancer stem cells in A549 and H446 cell lines

(2013) XIUPING YAN et al.   ONCOLOGY REPORTS

In Vitro Selection of Modified RNA Aptamers Against CD44 Cancer Stem Cell Marker

(2013) Nidaa Ababneh et al.   Nucleic Acid Therapeutics

In vivo SELEX for Identification of Brain-penetrating Aptamers

(2013) Congsheng Cheng et al.   Molecular Therapy-Nucleic Acids

RNA aptamers targeting cancer stem cell marker CD133

(2012) Sarah Shigdar et al.   CANCER LETTERS

Biologic Challenges in the Detection of Circulating Tumor Cells

(2012) S. A. Joosse et al.   CANCER RESEARCH

Targeted agents in the third-/fourth-line treatment of patients with advanced (stage III/IV) non-small cell lung cancer (NSCLC)

(2012) Corey J. Langer et al.   CANCER TREATMENT REVIEWS

Targeting Axl With an High-affinity Inhibitory Aptamer

(2012) Laura Cerchia et al.   MOLECULAR THERAPY

Novel MUC1 Aptamer Selectively Delivers Cytotoxic Agent to Cancer Cells In Vitro

(2012) Yan Hu et al.   PLoS One

Current Progress of RNA Aptamer-Based Therapeutics

(2012) Jiehua Zhou et al.   Frontiers in Genetics

RNA aptamer against a cancer stem cell marker epithelial cell adhesion molecule

(2011) Sarah Shigdar et al.   CANCER SCIENCE

Self-assemble gene delivery system for molecular targeting using nucleic acid aptamer

(2011) Tomoaki Kurosaki et al.   GENE

Evaluation and Prognostic Significance of Circulating Tumor Cells in Patients With Non–Small-Cell Lung Cancer

(2011) Matthew G. Krebs et al.   JOURNAL OF CLINICAL ONCOLOGY

A Neutralizing RNA Aptamer against EGFR Causes Selective Apoptotic Cell Death

(2011) Carla Lucia Esposito et al.   PLoS One

Development of a Lung Cancer Therapeutic Based on the Tumor Suppressor MicroRNA-34

(2010) J. F. Wiggins et al.   CANCER RESEARCH

Induction of Nonapoptotic Cell Death by Activated Ras Requires Inverse Regulation of Rac1 and Arf6

(2010) Haymanti Bhanot et al.   MOLECULAR CANCER RESEARCH

Recognition of subtype non-small cell lung cancer by DNA aptamers selected from living cells

(2009) Zilong Zhao et al.   ANALYST

Discovery and development of the G-rich oligonucleotide AS1411 as a novel treatment for cancer

(2009) Paula J. Bates et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Increased expression of inhibitor of apoptosis proteins, survivin and XIAP, in non-small cell lung carcinoma

(2009) Krepela   INTERNATIONAL JOURNAL OF ONCOLOGY

Verification of specific G-quadruplex structure by using a novel cyanine dye supramolecular assembly: II. The binding characterization with specific intramolecular G-quadruplex and the recognizing mechanism

(2009) Qianfan Yang et al.   NUCLEIC ACIDS RESEARCH