Therapeutic advances in Dravet syndrome: a targeted literature review

Adjunctive Cannabidiol in Patients with Dravet Syndrome: A Systematic Review and Meta-Analysis of Efficacy and Safety

(2020) Simona Lattanzi et al.   CNS DRUGS

Dravet syndrome: Treatment options and management of prolonged seizures

(2020) J. Helen Cross et al.   EPILEPSIA

Dose-Ranging Effect of Adjunctive Oral Cannabidiol vs Placebo on Convulsive Seizure Frequency in Dravet Syndrome

(2020) Ian Miller et al.   JAMA Neurology

Successful use of fenfluramine in nonconvulsive status epilepticus of Dravet syndrome

(2020) Nicola Specchio et al.   EPILEPSIA

Cannabidiol efficacy and clobazam status: A systematic review and meta‐analysis

(2020) Simona Lattanzi et al.   EPILEPSIA

Does cannabidiol have antiseizure activity independent of its interactions with clobazam? An appraisal of the evidence from randomized controlled trials

(2020) Meir Bialer et al.   EPILEPSIA

Fenfluramine acts as a positive modulator of sigma-1 receptors

(2020) Parthena Martin et al.   EPILEPSY & BEHAVIOR

Burden-of-illness and cost-driving factors in Dravet syndrome patients and carers: A prospective, multicenter study from Germany

(2019) Adam Strzelczyk et al.   EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY

Efficacy of the ketogenic diet in Chinese children with Dravet syndrome: A focus on neuropsychological development

(2019) Fangyun Liu et al.   EPILEPSY & BEHAVIOR

Burden and epidemiology of status epilepticus in infants, children, and adolescents: A population‐based study on German health insurance data

(2019) Susanne Schubert‐Bast et al.   EPILEPSIA

Stiripentol for the treatment of seizures in Dravet syndrome

(2019) Krista Eschbach et al.   Expert Review of Clinical Pharmacology

A multicenter, matched case-control analysis comparing burden-of-illness in Dravet syndrome to refractory epilepsy and seizure remission in patients and caregivers in Germany

(2019) Adam Strzelczyk et al.   EPILEPSIA

The outcomes of childhood convulsive status epilepticus

(2019) Richard F.M. Chin   EPILEPSY & BEHAVIOR

The Efficacy of Ketogenic Diet in 60 Chinese Patients With Dravet Syndrome

(2019) Xiaojuan Tian et al.   Frontiers in Neurology

Recent Advances in the Drug Treatment of Dravet Syndrome

(2019) Elaine C. Wirrell et al.   CNS DRUGS

Long-term outcomes after childhood convulsive status epilepticus

(2019) Suresh Pujar et al.   CURRENT OPINION IN PEDIATRICS

Seizure management and prescription patterns of anticonvulsants in Dravet syndrome: A multicenter cohort study from Germany and review of literature

(2019) Susanne Schubert-Bast et al.   EPILEPSY & BEHAVIOR

Stiripentol: A Review in Dravet Syndrome

(2019) James E. Frampton   DRUGS

Long‐term efficacy of add‐on stiripentol treatment in children, adolescents, and young adults with refractory epilepsies: A single center prospective observational study

(2019) Anna Rosati et al.   EPILEPSIA

Fenfluramine hydrochloride for the treatment of seizures in Dravet syndrome: a randomised, double-blind, placebo-controlled trial

(2019) Lieven Lagae et al.   LANCET

Fenfluramine for Treatment-Resistant Seizures in Patients With Dravet Syndrome Receiving Stiripentol-Inclusive Regimens

(2019) Rima Nabbout et al.   JAMA Neurology

Treatment Strategies for Dravet Syndrome

(2018) Kelly G. Knupp et al.   CNS DRUGS

Stiripentol efficacy and safety in Dravet syndrome: a 12-year observational study

(2018) Kenneth A Myers et al.   DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY

Influence of contraindicated medication use on cognitive outcome in Dravet syndrome and age at first afebrile seizure as a clinical predictor in SCN1A -related seizure phenotypes

(2018) Iris M. de Lange et al.   EPILEPSIA

Assessing the impact of caring for a child with Dravet syndrome: Results of a caregiver survey

(2018) Jonathan D. Campbell et al.   EPILEPSY & BEHAVIOR

The direct and indirect costs of Dravet Syndrome

(2018) Melanie D. Whittington et al.   EPILEPSY & BEHAVIOR

Prospective study of the efficacy of a ketogenic diet in 20 patients with Dravet syndrome

(2018) Ni Yan et al.   SEIZURE-EUROPEAN JOURNAL OF EPILEPSY

Individualized treatment approaches: Fenfluramine, a novel antiepileptic medication for the treatment of seizures in Dravet syndrome

(2018) Tilman Polster   EPILEPSY & BEHAVIOR

Lorcaserin therapy for severe epilepsy of childhood onset

(2018) Patricia Tolete et al.   NEUROLOGY

Progress report on new antiepileptic drugs: A summary of the Fourteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XIV). I. Drugs in preclinical and early clinical development

(2018) Meir Bialer et al.   EPILEPSIA

Long-term cannabidiol treatment in patients with Dravet syndrome: An open-label extension trial

(2018) Orrin Devinsky et al.   EPILEPSIA

Emerging drugs for the treatment of Dravet syndrome

(2018) Francesco Brigo et al.   EXPERT OPINION ON EMERGING DRUGS

A phase I, randomized, open-label, single-dose, 3-period crossover study to evaluate the drug-drug interaction between ZX008 (fenfluramine HCl oral solution) and a 
regimen of stiripentol, clobazam, and valproate in healthy subjects

(2018) Brooks Boyd et al.   INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS

Efficacy of Stiripentol and the Clinical Outcome in Dravet Syndrome

(2018) Edibe Pembegul Yıldız et al.   JOURNAL OF CHILD NEUROLOGY

Caregiver impact and health service use in high and low severity Dravet syndrome: A multinational cohort study

(2018) Lieven Lagae et al.   SEIZURE-EUROPEAN JOURNAL OF EPILEPSY

ILAE classification of the epilepsies: Position paper of the ILAE Commission for Classification and Terminology

(2017) Ingrid E. Scheffer et al.   EPILEPSIA

Dravet syndrome: Characteristics, comorbidities, and caregiver concerns

(2017) Nicole Villas et al.   EPILEPSY & BEHAVIOR

Ataluren in patients with nonsense mutation Duchenne muscular dystrophy (ACT DMD): a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial

(2017) Craig M McDonald et al.   LANCET

Trial of Cannabidiol for Drug-Resistant Seizures in the Dravet Syndrome

(2017) Orrin Devinsky et al.   NEW ENGLAND JOURNAL OF MEDICINE

Optimizing the Diagnosis and Management of Dravet Syndrome: Recommendations From a North American Consensus Panel

(2017) Elaine C. Wirrell et al.   PEDIATRIC NEUROLOGY

The mechanisms mediating the antiepileptic effects of the ketogenic diet, and potential opportunities for improvement with metabolism-altering drugs

(2017) Neil A. Youngson et al.   SEIZURE-EUROPEAN JOURNAL OF EPILEPSY

Efficacy of adjunctive vagus nerve stimulation in patients with Dravet syndrome: A meta-analysis of 68 patients

(2017) Maxine Dibué-Adjei et al.   SEIZURE-EUROPEAN JOURNAL OF EPILEPSY

Audit of use of stiripentol in adults with Dravet syndrome

(2016) S. Balestrini et al.   ACTA NEUROLOGICA SCANDINAVICA

Five-year extended follow-up status of 10 patients with Dravet syndrome treated with fenfluramine

(2016) Berten Ceulemans et al.   EPILEPSIA

Mortality in Dravet syndrome: A review

(2016) Sharon Shmuely et al.   EPILEPSY & BEHAVIOR

Patients with dravet syndrome in the era of stiripentol: A French cohort cross-sectional study

(2016) Paola De Liso et al.   EPILEPSY RESEARCH

Dravet syndrome in Sweden: a population-based study

(2015) Cecilia Rosander et al.   DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY

The incidence ofSCN1A-related Dravet syndrome in Denmark is 1:22,000: A population-based study from 2004 to 2009

(2015) Allan Bayat et al.   EPILEPSIA

The European patient with Dravet syndrome: Results from a parent-reported survey on antiepileptic drug use in the European population with Dravet syndrome

(2015) Luis Miguel Aras et al.   EPILEPSY & BEHAVIOR

Efficacy and tolerability of the ketogenic diet in Dravet syndrome – Comparison with various standard antiepileptic drug regimen

(2015) Anastasia Dressler et al.   EPILEPSY RESEARCH

Incidence of Dravet Syndrome in a US Population

(2015) Y. W. Wu et al.   PEDIATRICS

Dravet syndrome-From epileptic encephalopathy to channelopathy

(2014) Andreas Brunklaus et al.   EPILEPSIA

Evaluation of health-care utilization in patients with Dravet syndrome and on adjunctive treatment with stiripentol and clobazam

(2014) Adam Strzelczyk et al.   EPILEPSY & BEHAVIOR

Stiripentol in Dravet syndrome: Results of a retrospective U.S. study

(2013) Elaine C. Wirrell et al.   EPILEPSIA

The Ketogenic Diet in Dravet Syndrome

(2013) Linda Laux et al.   JOURNAL OF CHILD NEUROLOGY

Encephalopathy in children with Dravet syndrome is not a pure consequence of epilepsy

(2013) Rima Nabbout et al.   Orphanet Journal of Rare Diseases

Efficacy of verapamil as an adjunctive treatment in children with drug-resistant epilepsy: A pilot study

(2013) Francesco Nicita et al.   SEIZURE-EUROPEAN JOURNAL OF EPILEPSY

How Dravet syndrome became a model for studying childhood genetic epilepsies

(2012) C. Dravet   BRAIN

Successful use of fenfluramine as an add-on treatment for Dravet syndrome

(2012) Berten Ceulemans et al.   EPILEPSIA

Bromide in Patients with SCN1A-Mutations Manifesting as Dravet Syndrome

(2012) Jan Lotte et al.   NEUROPEDIATRICS

Current therapeutic procedures in Dravet syndrome

(2011) CATHERINE CHIRON   DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY

The ketogenic diet for Dravet syndrome and other epileptic encephalopathies: An Italian consensus

(2011) Pierangelo Veggiotti et al.   EPILEPSIA

Nonpharmacologic treatments of Dravet syndrome: Focus on the ketogenic diet

(2011) Roberto Horacio Caraballo   EPILEPSIA

Dravet syndrome: The long-term outcome

(2011) Pierre Genton et al.   EPILEPSIA

The core Dravet syndrome phenotype

(2011) Charlotte Dravet   EPILEPSIA

Comorbidities and predictors of health-related quality of life in Dravet syndrome

(2011) Andreas Brunklaus et al.   EPILEPSIA

Ketogenic diet also benefits Dravet syndrome patients receiving stiripentol: A prospective pilot study

(2011) Rima Nabbout et al.   EPILEPSIA