Treatment Strategies for Dravet Syndrome

Dravet syndrome: Characteristics, comorbidities, and caregiver concerns

(2017) Nicole Villas et al.   EPILEPSY & BEHAVIOR

Add-on stiripentol elevates serum valproate levels in patients with or without concomitant topiramate therapy

(2017) Toshihiro Jogamoto et al.   EPILEPSY RESEARCH

Vagus Nerve Stimulation in Intractable Epilepsy Associated With SCN1A Gene Abnormalities

(2017) Stephen P. Fulton et al.   JOURNAL OF CHILD NEUROLOGY

Clinical and genetic factors predicting Dravet syndrome in infants with SCN1A mutations

(2017) Valentina Cetica et al.   NEUROLOGY

Practice guideline summary: Sudden unexpected death in epilepsy incidence rates and risk factors

(2017) Cynthia Harden et al.   NEUROLOGY

Trial of Cannabidiol for Drug-Resistant Seizures in the Dravet Syndrome

(2017)   NEW ENGLAND JOURNAL OF MEDICINE

Cannabidiol attenuates seizures and social deficits in a mouse model of Dravet syndrome

(2017) Joshua S. Kaplan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Growth and endocrine function in children with Dravet syndrome

(2017) Krista Eschbach et al.   SEIZURE-EUROPEAN JOURNAL OF EPILEPSY

Efficacy of adjunctive vagus nerve stimulation in patients with Dravet syndrome: A meta-analysis of 68 patients

(2017) Maxine Dibué-Adjei et al.   SEIZURE-EUROPEAN JOURNAL OF EPILEPSY

Audit of use of stiripentol in adults with Dravet syndrome

(2016) S. Balestrini et al.   ACTA NEUROLOGICA SCANDINAVICA

Palliative epilepsy surgery in Dravet syndrome—case series and review of the literature

(2016) Brian J. Dlouhy et al.   CHILDS NERVOUS SYSTEM

Duration of use of oral cannabis extract in a cohort of pediatric epilepsy patients

(2016) Lauren Treat et al.   EPILEPSIA

Patients with dravet syndrome in the era of stiripentol: A French cohort cross-sectional study

(2016) Paola De Liso et al.   EPILEPSY RESEARCH

Mortality in Dravet syndrome

(2016) Monica S. Cooper et al.   EPILEPSY RESEARCH

Cannabidiol in patients with treatment-resistant epilepsy: an open-label interventional trial

(2016) Orrin Devinsky et al.   LANCET NEUROLOGY

Emerging Antiepileptic Drugs for Severe Pediatric Epilepsies

(2016) Basanagoud Mudigoudar et al.   Seminars in Pediatric Neurology

The incidence ofSCN1A-related Dravet syndrome in Denmark is 1:22,000: A population-based study from 2004 to 2009

(2015) Allan Bayat et al.   EPILEPSIA

Drug-drug interaction between clobazam and cannabidiol in children with refractory epilepsy

(2015) Alexandra L. Geffrey et al.   EPILEPSIA

Perceived efficacy of cannabidiol-enriched cannabis extracts for treatment of pediatric epilepsy: A potential role for infantile spasms and Lennox–Gastaut syndrome

(2015) Shaun A. Hussain et al.   EPILEPSY & BEHAVIOR

Parental reporting of response to oral cannabis extracts for treatment of refractory epilepsy

(2015) Craig A. Press et al.   EPILEPSY & BEHAVIOR

Nonintravenous midazolam versus intravenous or rectal diazepam for the treatment of early status epilepticus: A systematic review with meta-analysis

(2015) Francesco Brigo et al.   EPILEPSY & BEHAVIOR

Efficacy and tolerability of the ketogenic diet in Dravet syndrome – Comparison with various standard antiepileptic drug regimen

(2015) Anastasia Dressler et al.   EPILEPSY RESEARCH

Long-term safety and efficacy of stiripentol for the treatment of Dravet syndrome: A multicenter, open-label study in Japan

(2015) Yushi Inoue et al.   EPILEPSY RESEARCH

Amplicon Resequencing Identified Parental Mosaicism for Approximately 10% of “de novo”SCN1AMutations in Children with Dravet Syndrome

(2015) Xiaojing Xu et al.   HUMAN MUTATION

Cannabinoid Dose and Label Accuracy in Edible Medical Cannabis Products

(2015) Ryan Vandrey et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Neuroprotective activity of stiripentol with a possible involvement of voltage-dependent calcium and sodium channels

(2015) Marc Verleye et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Cannabinoids and Epilepsy

(2015) Evan C. Rosenberg et al.   Neurotherapeutics

Incidence of Dravet Syndrome in a US Population

(2015) Y. W. Wu et al.   PEDIATRICS

Targeting LDH enzymes with a stiripentol analog to treat epilepsy

(2015) N. Sada et al.   SCIENCE

Carbamazepine and oxcarbazepine in adult patients with Dravet syndrome: Friend or foe?

(2015) F.M. Snoeijen-Schouwenaars et al.   SEIZURE-EUROPEAN JOURNAL OF EPILEPSY

Lamotrigine can be beneficial in patients with Dravet syndrome

(2014) Linda Dalic et al.   DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY

Vagus nerve stimulation for drug-resistant epilepsy: A European long-term study up to 24 months in 347 children

(2014) Iren Orosz et al.   EPILEPSIA

Long-term course of Dravet syndrome: A study from an epilepsy center in Japan

(2014) Rumiko Takayama et al.   EPILEPSIA

A pilot double-blind trial using verapamil as adjuvant therapy for refractory seizures

(2014) Felippe Borlot et al.   EPILEPSY RESEARCH

Effectiveness of add-on stiripentol to clobazam and valproate in Japanese patients with Dravet syndrome: Additional supportive evidence

(2014) Yushi Inoue et al.   EPILEPSY RESEARCH

Intrahypothalamic injection of cannabidiol increases the extracellular levels of adenosine in nucleus accumbens in rats

(2014) Stephanie Mijangos-Moreno et al.   NEUROSCIENCE RESEARCH

Untangling the Dravet Syndrome Seizure Network: The Changing Face of a Rare Genetic Epilepsy

(2014) Ravi Chopra et al.   Epilepsy Currents

Stiripentol in refractory status epilepticus

(2013) Denise K. Grosenbaugh et al.   EPILEPSIA

Stiripentol in Dravet syndrome: Results of a retrospective U.S. study

(2013) Elaine C. Wirrell et al.   EPILEPSIA

Adjunctive use of verapamil in patients with refractory temporal lobe epilepsy: A pilot study

(2013) Ali A. Asadi-Pooya et al.   EPILEPSY & BEHAVIOR

Report of a parent survey of cannabidiol-enriched cannabis use in pediatric treatment-resistant epilepsy

(2013) Brenda E. Porter et al.   EPILEPSY & BEHAVIOR

The Ketogenic Diet in Dravet Syndrome

(2013) Linda Laux et al.   JOURNAL OF CHILD NEUROLOGY

Efficacy of verapamil as an adjunctive treatment in children with drug-resistant epilepsy: A pilot study

(2013) Francesco Nicita et al.   SEIZURE-EUROPEAN JOURNAL OF EPILEPSY

Drug screening in Scn1a zebrafish mutant identifies clemizole as a potential Dravet syndrome treatment

(2013) Scott C. Baraban et al.   Nature Communications

Prevalence of SCN1A mutations in children with suspected Dravet syndrome and intractable childhood epilepsy

(2012) Ji-wen Wang et al.   EPILEPSY RESEARCH

Mesial Temporal Sclerosis in a Cohort of Children With SCN1A Gene Mutation

(2012) Katherine Van Poppel et al.   JOURNAL OF CHILD NEUROLOGY

Bromide in Patients with SCN1A-Mutations Manifesting as Dravet Syndrome

(2012) Jan Lotte et al.   NEUROPEDIATRICS

Dravet syndrome as epileptic encephalopathy: evidence from long-term course and neuropathology

(2011) C. B. Catarino et al.   BRAIN

GABAA Receptor Physiology and Its Relationship to the Mechanism of Action of the 1,5-Benzodiazepine Clobazam

(2011) Raman Sankar   CNS DRUGS

Overall management of patients with Dravet syndrome

(2011) BERTEN CEULEMANS   DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY

Current therapeutic procedures in Dravet syndrome

(2011) CATHERINE CHIRON   DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY

Dravet syndrome history

(2011) CHARLOTTE DRAVET   DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY

Mortality in Dravet syndrome: Search for risk factors in Japanese patients

(2011) Masako Sakauchi et al.   EPILEPSIA

Electroencephalographic characteristics of Dravet syndrome

(2011) Michelle Bureau et al.   EPILEPSIA

Severe myoclonic epilepsy in infancy (Dravet syndrome) 30 years later

(2011) Charlotte Dravet et al.   EPILEPSIA

Cognitive development in children with Dravet syndrome

(2011) Francesca Ragona   EPILEPSIA

Nonpharmacologic treatments of Dravet syndrome: Focus on the ketogenic diet

(2011) Roberto Horacio Caraballo   EPILEPSIA

The pharmacologic treatment of Dravet syndrome

(2011) Catherine Chiron et al.   EPILEPSIA

Dravet syndrome: The long-term outcome

(2011) Pierre Genton et al.   EPILEPSIA

The ketogenic diet inhibits the mammalian target of rapamycin (mTOR) pathway

(2011) Sharon S. McDaniel et al.   EPILEPSIA

The effects of stiripentol on GABAA receptors

(2011) Janet L. Fisher   EPILEPSIA

Dravet syndrome and parent associations: The IDEA League experience with comorbid conditions, mortality, management, adaptation, and grief

(2011) Joan V. Skluzacek et al.   EPILEPSIA

The core Dravet syndrome phenotype

(2011) Charlotte Dravet   EPILEPSIA

Comorbidities and predictors of health-related quality of life in Dravet syndrome

(2011) Andreas Brunklaus et al.   EPILEPSIA

Ketogenic diet also benefits Dravet syndrome patients receiving stiripentol: A prospective pilot study

(2011) Rima Nabbout et al.   EPILEPSIA

Low long-term efficacy and tolerability of add-on rufinamide in patients with Dravet syndrome

(2011) A. Mueller et al.   EPILEPSY & BEHAVIOR

Genotype-phenotype associations in SCN1A-related epilepsies

(2011) S. M. Zuberi et al.   NEUROLOGY

Cannabidiol improves brain and liver function in a fulminant hepatic failure-induced model of hepatic encephalopathy in mice

(2010) Y Avraham et al.   BRITISH JOURNAL OF PHARMACOLOGY

Clinical course of young patients with Dravet syndrome after vagal nerve stimulation

(2010) Nelia Zamponi et al.   EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY

Metabolic Control of Vesicular Glutamate Transport and Release

(2010) Narinobu Juge et al.   NEURON

Unusual consequences of status epilepticus in Dravet syndrome

(2010) M. Chipaux et al.   SEIZURE-EUROPEAN JOURNAL OF EPILEPSY

A long-term follow-up study of Dravet syndrome up to adulthood

(2009) Mari Akiyama et al.   EPILEPSIA

Stiripentol open study in Japanese patients with Dravet syndrome

(2009) Yushi Inoue et al.   EPILEPSIA

Addition of verapamil in the treatment of severe myoclonic epilepsy in infancy

(2009) Paola Iannetti et al.   EPILEPSY RESEARCH

Cannabidiol Targets Mitochondria to Regulate Intracellular Ca2+ Levels

(2009) D. Ryan et al.   JOURNAL OF NEUROSCIENCE

Management of and prophylaxis against status epilepticus in children with severe myoclonic epilepsy in infancy (SMEI; Dravet syndrome) – A nationwide questionnaire survey in Japan

(2008) Takuya Tanabe et al.   BRAIN & DEVELOPMENT

Spotlight on Topiramate in Epilepsy1

(2008) Katherine A Lyseng-Williamson et al.   CNS DRUGS

Microchromosomal deletions involvingSCN1Aand adjacent genes in severe myoclonic epilepsy in infancy

(2008) Ji-wen Wang et al.   EPILEPSIA

Vagus nerve stimulation for refractory epilepsy in children: More to VNS than seizure frequency reduction

(2008) Amre Shahwan et al.   EPILEPSIA

Subunit-Specific Trafficking of GABAA Receptors during Status Epilepticus

(2008) H. P. Goodkin et al.   JOURNAL OF NEUROSCIENCE

Pharmacokinetics of P‐glycoprotein inhibition in the rat blood‐brain barrier

(2008) Stina Syvänen et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Vagus nerve stimulation in pediatric epileptic syndromes

(2008) E. Rossignol et al.   SEIZURE-EUROPEAN JOURNAL OF EPILEPSY

The orphan receptor GPR55 is a novel cannabinoid receptor

(2007) E Ryberg et al.   BRITISH JOURNAL OF PHARMACOLOGY