Impact of gene expression noise on organismal fitness and the efficacy of natural selection

Fundamental limits on the suppression of molecular fluctuations

(2010) Ioannis Lestas et al.   NATURE

What is flux balance analysis?

(2010) Jeffrey D Orth et al.   NATURE BIOTECHNOLOGY

Prevalent positive epistasis in Escherichia coli and Saccharomyces cerevisiae metabolic networks

(2010) Xionglei He et al.   NATURE GENETICS

Quantifying E. coli Proteome and Transcriptome with Single-Molecule Sensitivity in Single Cells

(2010) Y. Taniguchi et al.   SCIENCE

Intrinsic Protein Disorder and Interaction Promiscuity Are Widely Associated with Dosage Sensitivity

(2009) Tanya Vavouri et al.   CELL

Abundant Indispensable Redundancies in Cellular Metabolic Networks

(2009) Zhi Wang et al.   Genome Biology and Evolution

Positive selection for elevated gene expression noise in yeast

(2009) Zhihua Zhang et al.   Molecular Systems Biology

Stochasticity in Protein Levels Drives Colinearity of Gene Order in Metabolic Operons of Escherichia coli

(2009) Károly Kovács et al.   PLOS BIOLOGY

Evolutionary Plasticity and Innovations in Complex Metabolic Reaction Networks

(2009) João F. Matias Rodrigues et al.   PLoS Computational Biology

Why Is the Correlation between Gene Importance and Gene Evolutionary Rate So Weak?

(2009) Zhi Wang et al.   PLoS Genetics

Nature, Nurture, or Chance: Stochastic Gene Expression and Its Consequences

(2008) Arjun Raj et al.   CELL

Mistranslation-Induced Protein Misfolding as a Dominant Constraint on Coding-Sequence Evolution

(2008) D. Allan Drummond et al.   CELL

Selection to minimise noise in living systems and its implications for the evolution of gene expression

(2008) Ben Lehner   Molecular Systems Biology

Stochastic switching as a survival strategy in fluctuating environments

(2008) Murat Acar et al.   NATURE GENETICS

Population genomics of the wild yeast Saccharomyces paradoxus: Quantifying the life cycle

(2008) I. J. Tsai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cell-to-Cell Stochastic Variation in Gene Expression Is a Complex Genetic Trait

(2008) Juliet Ansel et al.   PLoS Genetics

Model-driven analysis of experimentally determined growth phenotypes for 465 yeast gene deletion mutants under 16 different conditions

(2008) Evan S Snitkin et al.   GENOME BIOLOGY