Heparan sulfate proteoglycan‐mediated dynamin‐dependent transport of neural stem cell exosomes in an in vitro blood–brain barrier model

Transport of Extracellular Vesicles across the Blood-Brain Barrier: Brain Pharmacokinetics and Effects of Inflammation

(2020) William A. Banks et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The Transport Mechanism of Extracellular Vesicles at the Blood-Brain Barrier

(2018) Junichi Matsumoto et al.   CURRENT PHARMACEUTICAL DESIGN

A small protein probe for correlated microscopy of endogenous proteins

(2018) Marit A. de Beer et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Designer exosomes produced by implanted cells intracerebrally deliver therapeutic cargo for Parkinson’s disease treatment

(2018) Ryosuke Kojima et al.   Nature Communications

Heparan Sulfate Proteoglycans as Emerging Players in Synaptic Specificity

(2018) Giuseppe Condomitti et al.   Frontiers in Molecular Neuroscience

A filter-free blood-brain barrier model to quantitatively study transendothelial delivery of nanoparticles by fluorescence spectroscopy

(2018) Edwin De Jong et al.   JOURNAL OF CONTROLLED RELEASE

Recent progress of drug nanoformulations targeting to brain

(2018) Abdur Rauf Khan et al.   JOURNAL OF CONTROLLED RELEASE

Nanocarriers as a powerful vehicle to overcome blood-brain barrier in treating neurodegenerative diseases: Focus on recent advances

(2018) Xiaoqian Niu et al.   Asian Journal of Pharmaceutical Sciences

Exosomes and Exosome-Inspired Vesicles for Targeted Drug Delivery

(2018) Sophia Antimisiaris et al.   Pharmaceutics

Lipids in exosomes: Current knowledge and the way forward

(2017) Tore Skotland et al.   PROGRESS IN LIPID RESEARCH

Targeting Malignant Brain Tumors with Antibodies

(2017) Rok Razpotnik et al.   Frontiers in Immunology

Delivery of Small Interfering RNA to Inhibit Vascular Endothelial Growth Factor in Zebrafish Using Natural Brain Endothelia Cell-Secreted Exosome Nanovesicles for the Treatment of Brain Cancer

(2016) Tianzhi Yang et al.   AAPS Journal

Integrins and heparan sulfate proteoglycans on hepatic stellate cells (HSC) are novel receptors for HSC-derived exosomes

(2016) Li Chen et al.   FEBS LETTERS

From blood–brain barrier to blood–brain interface: new opportunities for CNS drug delivery

(2016) William A. Banks   NATURE REVIEWS DRUG DISCOVERY

Entry of PIP3-containing polyplexes into MDCK epithelial cells by local apical-basal polarity reversal

(2016) Cuifeng Wang et al.   Scientific Reports

Exosomes as therapeutic drug carriers and delivery vehicles across biological membranes: current perspectives and future challenges

(2016) Dinh Ha et al.   Acta Pharmaceutica Sinica B

Neuronal and Vascular Interactions

(2015) Benjamin J. Andreone et al.   Annual Review of Neuroscience

Grapefruit-Derived Nanovectors Use an Activated Leukocyte Trafficking Pathway to Deliver Therapeutic Agents to Inflammatory Tumor Sites

(2015) Q. Wang et al.   CANCER RESEARCH

Heparan Sulphate as a Regulator of Leukocyte Recruitment in Inflammation

(2015) Archana Kumar et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

Cholesterol-loaded nanoparticles ameliorate synaptic and cognitive function in Huntington's disease mice

(2015) M. Valenza et al.   EMBO Molecular Medicine

Exosomes as drug delivery vehicles for Parkinson's disease therapy

(2015) Matthew J. Haney et al.   JOURNAL OF CONTROLLED RELEASE

Effect of exosomes derived from multipluripotent mesenchymal stromal cells on functional recovery and neurovascular plasticity in rats after traumatic brain injury

(2015) Yanlu Zhang et al.   JOURNAL OF NEUROSURGERY

Tumour exosome integrins determine organotropic metastasis

(2015) Ayuko Hoshino et al.   NATURE

The Molecular Constituents of the Blood–Brain Barrier

(2015) Brian Wai Chow et al.   TRENDS IN NEUROSCIENCES

Demystifying Heparan Sulfate–Protein Interactions

(2014) Ding Xu et al.   Annual Review of Biochemistry

Biogenesis, Secretion, and Intercellular Interactions of Exosomes and Other Extracellular Vesicles

(2014) Marina Colombo et al.   Annual Review of Cell and Developmental Biology

Systemic exosomal siRNA delivery reduced alpha-synuclein aggregates in brains of transgenic mice

(2014) J. Mark Cooper et al.   MOVEMENT DISORDERS

Therapeutic bispecific antibodies cross the blood-brain barrier in nonhuman primates

(2014) Y. J. Yu et al.   Science Translational Medicine

Thecis-acting signals that target proteins to exosomes and microvesicles

(2013) Jr-Ming Yang et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Grape Exosome-like Nanoparticles Induce Intestinal Stem Cells and Protect Mice From DSS-Induced Colitis

(2013) Songwen Ju et al.   MOLECULAR THERAPY

Development, maintenance and disruption of the blood-brain barrier

(2013) Birgit Obermeier et al.   NATURE MEDICINE

Transmigration of Neural Stem Cells across the Blood Brain Barrier Induced by Glioma Cells

(2013) Mónica Díaz-Coránguez et al.   PLoS One

Cancer cell exosomes depend on cell-surface heparan sulfate proteoglycans for their internalization and functional activity

(2013) H. C. Christianson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nonviral Gene Delivery Vectors Use Syndecan-Dependent Transport Mechanisms in Filopodia To Reach the Cell Surface

(2012) Zia ur Rehman et al.   ACS Nano

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Protein Targeting to Exosomes/Microvesicles by Plasma Membrane Anchors

(2011) Beiyi Shen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Protein kinase A inhibition modulates the intracellular routing of gene delivery vehicles in HeLa cells, leading to productive transfection

(2011) Zia ur Rehman et al.   JOURNAL OF CONTROLLED RELEASE

Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes

(2011) Lydia Alvarez-Erviti et al.   NATURE BIOTECHNOLOGY

Heparan Sulfate Proteoglycans

(2011) S. Sarrazin et al.   Cold Spring Harbor Perspectives in Biology

Surface Characteristics of Nanoparticles Determine Their Intracellular Fate in and Processing by Human Blood–Brain Barrier Endothelial Cells In Vitro

(2010) Julia V Georgieva et al.   MOLECULAR THERAPY

Insight into the role of HSPG in the cellular uptake of apolipoprotein E-derived peptide micelles and liposomes

(2008) Eik Leupold et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Suitability of various membrane lipophilic probes for the detection of trogocytosis by flow cytometry

(2008) Sandrine Daubeuf et al.   CYTOMETRY PART A

Stem and progenitor cell-mediated tumor selective gene therapy

(2008) K S Aboody et al.   GENE THERAPY

Molecular Mechanism of Systemic Delivery of Neural Precursor Cells to the Brain: Assembly of Brain Endothelial Apical Cups and Control of Transmigration by CD44

(2008) Christine Rampon et al.   STEM CELLS