Heparan Sulfate Proteoglycans as Emerging Players in Synaptic Specificity

Astrocyte-Secreted Glypican 4 Regulates Release of Neuronal Pentraxin 1 from Axons to Induce Functional Synapse Formation

(2017) Isabella Farhy-Tselnicker et al.   NEURON

Mutations in Human Accelerated Regions Disrupt Cognition and Social Behavior

(2016) Ryan N. Doan et al.   CELL

Comprehensive Classification of Retinal Bipolar Neurons by Single-Cell Transcriptomics

(2016) Karthik Shekhar et al.   CELL

2- and 6-O-sulfated proteoglycans have distinct and complementary roles in cranial axon guidance and motor neuron migration

(2016) Miguel Tillo et al.   DEVELOPMENT

Conservation of anatomically restricted glycosaminoglycan structures in divergent nematode species

(2016) Matthew Attreed et al.   GLYCOBIOLOGY

Adult mouse cortical cell taxonomy revealed by single cell transcriptomics

(2016) Bosiljka Tasic et al.   NATURE NEUROSCIENCE

Single-cell RNAseq reveals cell adhesion molecule profiles in electrophysiologically defined neurons

(2016) Csaba Földy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hipposeq: a comprehensive RNA-seq database of gene expression in hippocampal principal neurons

(2016) Mark S Cembrowski et al.   eLife

The Extracellular and Cytoplasmic Domains of Syndecan Cooperate Postsynaptically to Promote Synapse Growth at the Drosophila Neuromuscular Junction

(2016) Margaret U. Nguyen et al.   PLoS One

Postsynaptic SDC2 induces transsynaptic signaling via FGF22 for bidirectional synaptic formation

(2016) Hsiao-Tang Hu et al.   Scientific Reports

Ig Superfamily Ligand and Receptor Pairs Expressed in Synaptic Partners in Drosophila

(2015) Liming Tan et al.   CELL

Specification of synaptic connectivity by cell surface interactions

(2015) Joris de Wit et al.   NATURE REVIEWS NEUROSCIENCE

PTPσ functions as a presynaptic receptor for the glypican-4/LRRTM4 complex and is essential for excitatory synaptic transmission

(2015) Ji Seung Ko et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The balancing act of GABAergic synapse organizers

(2015) Jaewon Ko et al.   TRENDS IN MOLECULAR MEDICINE

Demystifying Heparan Sulfate–Protein Interactions

(2014) Ding Xu et al.   Annual Review of Biochemistry

Cellular and Molecular Mechanisms of Synaptic Specificity

(2014) Shaul Yogev et al.   Annual Review of Cell and Developmental Biology

Perlecan Antagonizes Collagen IV and ADAMTS9/GON-1 in Restricting the Growth of Presynaptic Boutons

(2014) J. Qin et al.   JOURNAL OF NEUROSCIENCE

Synaptic, transcriptional and chromatin genes disrupted in autism

(2014) Silvia De Rubeis et al.   NATURE

An Extracellular Interactome of Immunoglobulin and LRR Proteins Reveals Receptor-Ligand Networks

(2013) Engin Özkan et al.   CELL

Integrative Functional Genomic Analyses Implicate Specific Molecular Pathways and Circuits in Autism

(2013) Neelroop N. Parikshak et al.   CELL

Identification of the Proteoglycans Bound by Members of the Sonic Hedgehog Pathway♦

(2013)   JOURNAL OF BIOLOGICAL CHEMISTRY

Perlecan regulates bidirectional Wnt signaling at theDrosophilaneuromuscular junction

(2013) Keisuke Kamimura et al.   JOURNAL OF CELL BIOLOGY

The Developmental Brain Gene NPAS3 Contains the Largest Number of Accelerated Regulatory Sequences in the Human Genome

(2013) Gretel B. Kamm et al.   MOLECULAR BIOLOGY AND EVOLUTION

Unbiased Discovery of Glypican as a Receptor for LRRTM4 in Regulating Excitatory Synapse Development

(2013) Joris de Wit et al.   NEURON

An LRRTM4-HSPG Complex Mediates Excitatory Synapse Development on Dentate Gyrus Granule Cells

(2013) Tabrez J. Siddiqui et al.   NEURON

LAR-RPTPs: synaptic adhesion molecules that shape synapse development

(2013) Ji Won Um et al.   TRENDS IN CELL BIOLOGY

Protein tyrosine phosphatases PTPδ, PTPσ, and LAR: presynaptic hubs for synapse organization

(2013) Hideto Takahashi et al.   TRENDS IN NEUROSCIENCES

Heparan Sulfate Biosynthesis

(2012) Johan Kreuger et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Astrocyte glypicans 4 and 6 promote formation of excitatory synapses via GluA1 AMPA receptors

(2012) Nicola J. Allen et al.   NATURE

Direct visualization of specifically modified extracellular glycans in living animals

(2012) Matthew Attreed et al.   NATURE METHODS

Autism-like socio-communicative deficits and stereotypies in mice lacking heparan sulfate

(2012) F. Irie et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Targeted Glycan-Related Gene Screen Reveals Heparan Sulfate Proteoglycan Sulfation Regulates WNT and BMP Trans-Synaptic Signaling

(2012) Neil Dani et al.   PLoS Genetics

Shaping Cells and Organs in Drosophila by Opposing Roles of Fat Body-Secreted Collagen IV and Perlecan

(2011) José Carlos Pastor-Pareja et al.   DEVELOPMENTAL CELL

Sarm1, a negative regulator of innate immunity, interacts with syndecan-2 and regulates neuronal morphology

(2011) Chiung-Ya Chen et al.   JOURNAL OF CELL BIOLOGY

Heparan Sulfate Proteoglycans

(2011) S. Sarrazin et al.   Cold Spring Harbor Perspectives in Biology

Genetics and Cell Biology of Building Specific Synaptic Connectivity

(2010) Kang Shen et al.   Annual Review of Neuroscience

Synaptic organizing complexes

(2010) Tabrez J Siddiqui et al.   CURRENT OPINION IN NEUROBIOLOGY

Distinct FGFs promote differentiation of excitatory and inhibitory synapses

(2010) Akiko Terauchi et al.   NATURE

Functional impact of global rare copy number variation in autism spectrum disorders

(2010) Dalila Pinto et al.   NATURE

Molecular Mechanisms of Synaptic Specificity in Developing Neural Circuits

(2010) Megan E. Williams et al.   NEURON

A Genome-Wide Association Study of Neuroticism in a Population-Based Sample

(2010) Federico C. F. Calboli et al.   PLoS One

Mechanisms and Molecules of Neuronal Wiring: A Primer

(2010) A. L. Kolodkin et al.   Cold Spring Harbor Perspectives in Biology

Extracellular Matrix: Functions in the Nervous System

(2010) C. S. Barros et al.   Cold Spring Harbor Perspectives in Biology

Many Paths to Synaptic Specificity

(2009) Joshua R. Sanes et al.   Annual Review of Cell and Developmental Biology

Gabapentin Receptor α2δ-1 Is a Neuronal Thrombospondin Receptor Responsible for Excitatory CNS Synaptogenesis

(2009) Çagla Eroglu et al.   CELL

Common genetic variants on 5p14.1 associate with autism spectrum disorders

(2009) Kai Wang et al.   NATURE

An Unbiased Expression Screen for Synaptogenic Proteins Identifies the LRRTM Protein Family as Synaptic Organizers

(2009) Michael W. Linhoff et al.   NEURON

LRRTM2 Interacts with Neurexin1 and Regulates Excitatory Synapse Formation

(2009) Joris de Wit et al.   NEURON

LRRTM2 Functions as a Neurexin Ligand in Promoting Excitatory Synapse Formation

(2009) Jaewon Ko et al.   NEURON

Extracellular Sugar Modifications Provide Instructive and Cell-Specific Information for Axon-Guidance Choices

(2008) Hannes E. Bülow et al.   CURRENT BIOLOGY

Glypican-3 Inhibits Hedgehog Signaling during Development by Competing with Patched for Hedgehog Binding

(2008) Mariana I. Capurro et al.   DEVELOPMENTAL CELL

Differential involvement of the extracellular 6-O-endosulfatases Sulf1 and Sulf2 in brain development and neuronal and behavioural plasticity

(2008) Ina Kalus et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Gene discovery through imaging genetics: identification of two novel genes associated with schizophrenia

(2008) S G Potkin et al.   MOLECULAR PSYCHIATRY

Heparan sulfate regulates ephrin-A3/EphA receptor signaling

(2008) F. Irie et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA