Multimodular type I polyketide synthases in algae evolve by module duplications and displacement of AT domains in trans

antiSMASH 3.0—a comprehensive resource for the genome mining of biosynthetic gene clusters

(2015) Tilmann Weber et al.   NUCLEIC ACIDS RESEARCH

Genome Sequence and Transcriptome Analyses of Chrysochromulina tobin: Metabolic Tools for Enhanced Algal Fitness in the Prominent Order Prymnesiales (Haptophyceae)

(2015) Blake T. Hovde et al.   PLoS Genetics

InterProScan 5: genome-scale protein function classification

(2014) P. Jones et al.   BIOINFORMATICS

Recent advances in genome-based polyketide discovery

(2014) Eric JN Helfrich et al.   CURRENT OPINION IN BIOTECHNOLOGY

Polyketide biosynthesis in dinoflagellates: what makes it different?

(2014) Ryan M. Van Wagoner et al.   NATURAL PRODUCT REPORTS

Structure of a modular polyketide synthase

(2014) Somnath Dutta et al.   NATURE

The Number, Speed, and Impact of Plastid Endosymbioses in Eukaryotic Evolution

(2013) Patrick J. Keeling   Annual Review of Plant Biology

Draft Assembly of the Symbiodinium minutum Nuclear Genome Reveals Dinoflagellate Gene Structure

(2013) Eiichi Shoguchi et al.   CURRENT BIOLOGY

Pan genome of the phytoplankton Emiliania underpins its global distribution

(2013) Betsy A. Read et al.   NATURE

antiSMASH 2.0—a versatile platform for genome mining of secondary metabolite producers

(2013) Kai Blin et al.   NUCLEIC ACIDS RESEARCH

Structure/Function Analysis of a Type III Polyketide Synthase in the Brown Alga Ectocarpus siliculosus Reveals a Biochemical Pathway in Phlorotannin Monomer Biosynthesis

(2013) L. Meslet-Cladiere et al.   PLANT CELL

Improving the coverage of the cyanobacterial phylum using diversity-driven genome sequencing

(2013) P. M. Shih et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Explorations of catalytic domains in non-ribosomal peptide synthetase enzymology

(2012) Gene H. Hur et al.   NATURAL PRODUCT REPORTS

The structures of type I polyketide synthases

(2012) Adrian T. Keatinge-Clay   NATURAL PRODUCT REPORTS

Putative Monofunctional Type I Polyketide Synthase Units: A Dinoflagellate-Specific Feature?

(2012) Karsten Eichholz et al.   PLoS One

ProtTest 3: fast selection of best-fit models of protein evolution

(2011) Diego Darriba et al.   BIOINFORMATICS

Widespread Occurrence of Secondary Lipid Biosynthesis Potential in Microbial Lineages

(2011) Christine N. Shulse et al.   PLoS One

Niche of harmful alga Aureococcus anophagefferens revealed through ecogenomics

(2011) C. J. Gobler et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dinoflagellate Genome Evolution

(2010) Jennifer H. Wisecaver et al.   Annual Review of Microbiology

Unraveling algal lipid metabolism: Recent advances in gene identification

(2010) Inna Khozin-Goldberg et al.   BIOCHIMIE

Genome-Wide Phylogenetic Comparative Analysis of Plant Transcriptional Regulation: A Timeline of Loss, Gain, Expansion, and Correlation with Complexity

(2010) Daniel Lang et al.   Genome Biology and Evolution

Biosynthesis and Molecular Genetics of Polyketides in Marine Dinoflagellates

(2010) Ralf Kellmann et al.   Marine Drugs

Prymnesins: Toxic Metabolites of the Golden Alga, Prymnesium parvum Carter (Haptophyta)

(2010) Schonna R. Manning et al.   Marine Drugs

Structure and function of the chalcone synthase superfamily of plant type III polyketide synthases

(2010) Ikuro Abe et al.   NATURAL PRODUCT REPORTS

Biosynthesis of polyketides by trans-AT polyketide synthases

(2010) Jörn Piel   NATURAL PRODUCT REPORTS

The Ectocarpus genome and the independent evolution of multicellularity in brown algae

(2010) J. Mark Cock et al.   NATURE

New Algorithms and Methods to Estimate Maximum-Likelihood Phylogenies: Assessing the Performance of PhyML 3.0

(2010) Stéphane Guindon et al.   SYSTEMATIC BIOLOGY

The Biosynthetic Logic of Polyketide Diversity

(2009) Christian Hertweck   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Mobyle: a new full web bioinformatics framework

(2009) B. Neron et al.   BIOINFORMATICS

Evolution of metabolic diversity: Insights from microbial polyketide synthases

(2009) Holger Jenke-Kodama et al.   PHYTOCHEMISTRY

EPoS: a modular software framework for phylogenetic analysis

(2008) T. Griebel et al.   BIOINFORMATICS

The multienzyme architecture of eukaryotic fatty acid synthases

(2008) Marc Leibundgut et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Phylogeny.fr: robust phylogenetic analysis for the non-specialist

(2008) A. Dereeper et al.   NUCLEIC ACIDS RESEARCH

Evolution of polyketide synthases in bacteria

(2008) C. P. Ridley et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Toxic Dinoflagellate Karenia brevis Encodes Novel Type I-like Polyketide Synthases Containing Discrete Catalytic Domains

(2008) Emily A. Monroe et al.   PROTIST

Novel Insights into Evolution of Protistan Polyketide Synthases through Phylogenomic Analysis

(2007) Uwe John et al.   PROTIST