COVID‐19: A Case for Inhibiting NLRP3 Inflammasome, Suppression of Inflammation with Curcumin?

NLRP3 Inflammasome—A Key Player in Antiviral Responses

(2020) Chunyuan Zhao et al.   Frontiers in Immunology

Impact of curcumin supplementation on expression of inflammatory transcription factors in hemodialysis patients: A pilot randomized, double-blind, controlled study

(2020) Livia Alvarenga et al.   CLINICAL NUTRITION

Reduction and Functional Exhaustion of T Cells in Patients With Coronavirus Disease 2019 (COVID-19)

(2020) Bo Diao et al.   Frontiers in Immunology

COVID-19 pathophysiology: A review

(2020) Koichi Yuki et al.   CLINICAL IMMUNOLOGY

Inflammasomes and Pyroptosis as Therapeutic Targets for COVID-19

(2020) Jeremy K. Y. Yap et al.   JOURNAL OF IMMUNOLOGY

Severe COVID-19: NLRP3 Inflammasome Dysregulated

(2020) Daan F. van den Berg et al.   Frontiers in Immunology

Curcumin attenuates murine lupus via inhibiting NLRP3 inflammasome

(2019) Jijun Zhao et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Th17 Cells and the IL-23/IL-17 Axis in the Pathogenesis of Periodontitis and Immune-Mediated Inflammatory Diseases

(2019) Kübra Bunte et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Direct pulmonary delivery of solubilized curcumin reduces severity of lethal pneumonia

(2019) Boya Zhang et al.   FASEB JOURNAL

The NLRP3 inflammasome is involved with the pathogenesis of Mayaro virus

(2019) Luiza A. de Castro-Jorge et al.   PLoS Pathogens

Curcumin attenuates potassium oxonate-induced hyperuricemia and kidney inflammation in mice

(2019) Yonger Chen et al.   BIOMEDICINE & PHARMACOTHERAPY

Monosodium Urate Crystals Activate the Inflammasome in Primary Progressive Multiple Sclerosis

(2018) Federica Piancone et al.   Frontiers in Immunology

Targeting Peroxiredoxin 1 by a Curcumin Analogue, AI-44, Inhibits NLRP3 Inflammasome Activation and Attenuates Lipopolysaccharide-Induced Sepsis in Mice

(2018) Wen Liu et al.   JOURNAL OF IMMUNOLOGY

Curcumin and allopurinol ameliorate fructose-induced hepatic inflammation in rats via miR-200a-mediated TXNIP/NLRP3 inflammasome inhibition

(2018) Xiao-Qing Ding et al.   PHARMACOLOGICAL RESEARCH

Curcumin Reduces Neuronal Loss and Inhibits the NLRP3 Inflammasome Activation in an Epileptic Rat Model

(2018) Qianchao He et al.   CURRENT NEUROVASCULAR RESEARCH

Curcumin alleviates DSS-induced colitis via inhibiting NLRP3 inflammsome activation and IL-1β production

(2018) Zizhen Gong et al.   MOLECULAR IMMUNOLOGY

Curcumin relieves depressive-like behaviors via inhibition of the NLRP3 inflammasome and kynurenine pathway in rats suffering from chronic unpredictable mild stress

(2018) Wen-yuan Zhang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Curcumin Prevents Osteoarthritis by Inhibiting the Activation of Inflammasome NLRP3

(2017) Yufeng Sun et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

SARS coronavirus papain-like protease up-regulates the collagen expression through non-Samd TGF-β1 signaling

(2017) Ching-Ying Wang et al.   VIRUS RESEARCH

Effects of curcumin on serum cytokine concentrations in subjects with metabolic syndrome: A post-hoc analysis of a randomized controlled trial

(2016) Yunes Panahi et al.   BIOMEDICINE & PHARMACOTHERAPY

Inflammasomes and its importance in viral infections

(2016) Gaurav Shrivastava et al.   IMMUNOLOGIC RESEARCH

Curcumin and Health

(2016) Mario Pulido-Moran et al.   MOLECULES

Curcumin suppresses transforming growth factor-β1-induced cardiac fibroblast differentiation via inhibition of Smad-2 and p38 MAPK signaling pathways

(2016) HUZI LIU et al.   Experimental and Therapeutic Medicine

Curcumin ameliorates neuropathic pain by down-regulating spinal IL-1β via suppressing astroglial NALP1 inflammasome and JAK2-STAT3 signalling

(2016) Shenbin Liu et al.   Scientific Reports

Curcumin Represses NLRP3 Inflammasome Activation via TLR4/MyD88/NF-κB and P2X7R Signaling in PMA-Induced Macrophages

(2016) Fanqi Kong et al.   Frontiers in Pharmacology

Suppression of NLRP3 Inflammasome Activation Ameliorates Chronic Kidney Disease-Induced Cardiac Fibrosis and Diastolic Dysfunction

(2016) Antoinette Bugyei-Twum et al.   Scientific Reports

Oxidative stress response and Nrf2 signaling in aging

(2015) Hongqiao Zhang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Curcumin suppresses NLRP3 inflammasome activation and protects against LPS-induced septic shock

(2015) Zizhen Gong et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Curcumin attenuates glutamate neurotoxicity in the hippocampus by suppression of ER stress-associated TXNIP/NLRP3 inflammasome activation in a manner dependent on AMPK

(2015) Ying Li et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Curcumin: A Double Hit on Malignant Mesothelioma

(2014) J. M. Miller et al.   Cancer Prevention Research

Synthesis, Characterization, Mössbauer Parameters, and Antitumor Activity of Fe(III) Curcumin Complex

(2013) Mutasim Ibrahim Khalil et al.   BIOINORGANIC CHEMISTRY AND APPLICATIONS

The Targets of Curcumin

(2012) Hongyu Zhou et al.   CURRENT DRUG TARGETS

Curcumin reverses T cell-mediated adaptive immune dysfunctions in tumor-bearing hosts

(2010) Sankar Bhattacharyya et al.   Cellular & Molecular Immunology

The role of inflammation in epilepsy

(2010) Annamaria Vezzani et al.   Nature Reviews Neurology

Fluorescence Study of the Curcumin−Casein Micelle Complexation and Its Application as a Drug Nanocarrier to Cancer Cells

(2008) Abhishek Sahu et al.   BIOMACROMOLECULES

Curcumin: Preventive and Therapeutic Properties in Laboratory Studies and Clinical Trials

(2007) Alexios S. Strimpakos et al.   ANTIOXIDANTS & REDOX SIGNALING