Curcumin Represses NLRP3 Inflammasome Activation via TLR4/MyD88/NF-κB and P2X7R Signaling in PMA-Induced Macrophages

Curcumin Modulates Macrophage Polarization Through the Inhibition of the Toll-Like Receptor 4 Expression and its Signaling Pathways

(2015) Yaoyao Zhou et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

The P2X7 receptor directly interacts with the NLRP3 inflammasome scaffold protein

(2015) Alessia Franceschini et al.   FASEB JOURNAL

IL-1β production is dependent on the activation of purinergic receptors and NLRP3 pathway in human macrophages

(2015) Thomas Gicquel et al.   FASEB JOURNAL

P2X7R is involved in the progression of atherosclerosis by promoting NLRP3 inflammasome activation

(2015) KUANG PENG et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Vitamin D3Metabolites Enhance the NLRP3-Dependent Secretion of IL-1β From Human THP-1 Monocytic Cells

(2015) Sarah E. Tulk et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Curcumin suppresses NLRP3 inflammasome activation and protects against LPS-induced septic shock

(2015) Zizhen Gong et al.   MOLECULAR NUTRITION & FOOD RESEARCH

IRAK1 mediates TLR4-induced ABCA1 downregulation and lipid accumulation in VSMCs

(2015) L Guo et al.   Cell Death & Disease

Curcumin inhibits EMMPRIN and MMP-9 expression through AMPK-MAPK and PKC signaling in PMA induced macrophages

(2014) Jiatian Cao et al.   Journal of Translational Medicine

Silence of NLRP3 Suppresses Atherosclerosis and Stabilizes Plaques in Apolipoprotein E-Deficient Mice

(2014) Fei Zheng et al.   MEDIATORS OF INFLAMMATION

Curcumin inhibits oxLDL-induced CD36 expression and foam cell formation through the inhibition of p38 MAPK phosphorylation

(2013) Kyoung-jin Min et al.   FOOD AND CHEMICAL TOXICOLOGY

P2X7 receptor is expressed in human vessels and might play a role in atherosclerosis

(2013) Mariarosaria Piscopiello et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Curcumin Inhibits Imiquimod-Induced Psoriasis-Like Inflammation by Inhibiting IL-1beta and IL-6 Production in Mice

(2013) Jun Sun et al.   PLoS One

Molecular mechanisms of curcumin action: Gene expression

(2012) Shishir Shishodia   BIOFACTORS

The Inflammasomes

(2010) Kate Schroder et al.   CELL

NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

(2010) Peter Duewell et al.   NATURE

Cholesterol Crystals Activate the NLRP3 Inflammasome in Human Macrophages: A Novel Link between Cholesterol Metabolism and Inflammation

(2010) Kristiina Rajamäki et al.   PLoS One

The Inflammasomes: Guardians of the Body

(2009) Fabio Martinon et al.   Annual Review of Immunology

Macrophage heterogeneity in atherosclerotic plaques

(2009) Jason L Johnson et al.   CURRENT OPINION IN LIPIDOLOGY

Berberine reduces both MMP-9 and EMMPRIN expression through prevention of p38 pathway activation in PMA-induced macrophages

(2009) Zhouqing Huang et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Cutting Edge: NF- B Activating Pattern Recognition and Cytokine Receptors License NLRP3 Inflammasome Activation by Regulating NLRP3 Expression

(2009) F. G. Bauernfeind et al.   JOURNAL OF IMMUNOLOGY

Chemokines in Atherosclerosis

(2008) Alma Zernecke et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY