Enantioselective Formal Arylation of (7‐Aza)isatylidene Malononitriles with α′‐Alkylidene‐2‐cyclohexenones

Bifunctional N-Heterocyclic Carbenes Derived from l-Pyroglutamic Acid and Their Applications in Enantioselective Organocatalysis

(2020) Xiang-Yu Chen et al.   ACCOUNTS OF CHEMICAL RESEARCH

Asymmetric Formal [5 + 3] Cycloadditions with Unmodified Morita–Baylis–Hillman Alcohols via Double Activation Catalysis

(2019) Qian-Qian Yang et al.   ACS Catalysis

Catalytic Enantioselective Construction of Spiro Quaternary Carbon Stereocenters

(2019) Peng-Wei Xu et al.   ACS Catalysis

Asymmetric Allylic Alkylation with Deconjugated Carbonyl Compounds: Direct Vinylogous Umpolung Strategy

(2019) Guang-Yao Ran et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Deacetylative Amination of Acetyl Arenes and Alkanes with C–C Bond Cleavage

(2019) Kengo Hyodo et al.   ORGANIC LETTERS

Rhodium-Catalyzed Enantioselective Addition of Arylboroxines to Isatin-Derived N-Boc Ketimines Using Chiral Phosphite–Olefin Ligands: Asymmetric Synthesis of 3-Aryl-3-amino-2-oxindoles

(2019) Yue-Na Yu et al.   ORGANIC LETTERS

Double Thiol-Chiral Brønsted Base Catalysis: Asymmetric Cross Rauhut–Currier Reaction and Sequential [4 + 2] Annulation for Assembly of Different Activated Olefins

(2019) Zhi Zhou et al.   ORGANIC LETTERS

Aromatic C–H Bond Functionalized via Zwitterion Intermediates to Construct Bioxindole Containing Continuous Quaternary Carbons

(2019) Li Niu et al.   JOURNAL OF ORGANIC CHEMISTRY

Synthesis of (±)‐ cis ‐1‐Aryl‐3‐oxo‐2,3‐dihydro‐1 H ‐benzo[ f ]chromene‐2‐carbonitriles and (±)‐ trans ‐4‐Aryl‐2‐oxo‐3,4‐dihydro‐2 H ‐benzo[ h ]chromene‐3‐carbonitriles

(2019) Kamar Mkaouar et al.   ChemistrySelect

Organocatalytic Enantioselective Cross-Vinylogous Rauhut-Currier Reaction of Methyl Coumalate with Enals

(2018) Qiwen Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric [4+2] annulations to construct norcamphor scaffolds with 2-cyclopentenone via double amine–thiol catalysis

(2018) Qian-Qian Yang et al.   CHEMICAL COMMUNICATIONS

α-Functionalization of 2-Vinylpyridines via a Chiral Phosphine Catalyzed Enantioselective Cross Rauhut–Currier Reaction

(2018) Cong Qin et al.   ORGANIC LETTERS

Nickel(II)-catalyzed addition reaction of arylboronic acids to isatins

(2018) Yu-Yang Zhang et al.   TETRAHEDRON

Co(III)-Catalyzed Coupling-Cyclization of Aryl C–H Bonds with α-Diazoketones Involving Wolff Rearrangement

(2018) Xinwei Hu et al.   ACS Catalysis

Catalytic and Enantioselective Direct α-Alkylation of 3-Aryl and 3-Alkyl Oxindole Using Quinine-Derived Urea Catalyst

(2018) Monissa C. Paderes et al.   ChemistrySelect

Synthesis of meta -Arylated Phenol Derivatives by Rhodium(I)-Catalyzed Arylation of Quinone Monoacetal

(2018) Jianhang Huang et al.   ADVANCED SYNTHESIS & CATALYSIS

Phosphine-Catalyzed Asymmetric Organic Reactions

(2018) Huanzhen Ni et al.   CHEMICAL REVIEWS

Sulfinate and Carbene Co-catalyzed Rauhut-Currier Reaction for Enantioselective Access to Azepino[1,2-a ]indoles

(2018) Xingxing Wu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chemoselective and Highly Rate Accelerated Intramolecular Aza-Morita–Baylis–Hillman Reaction

(2018) Kishor Chandra Bharadwaj   JOURNAL OF ORGANIC CHEMISTRY

Switchable regioselectivity in amine-catalysed asymmetric cycloadditions

(2017) Zhi Zhou et al.   Nature Chemistry

Spiroannulation of Oxindoles via Aryne and Alkyne Incorporation: Substituent-Diverted, Transition-Metal-Free, One-Pot Access to Spirooxindoles

(2017) Ramesh Samineni et al.   ORGANIC LETTERS

Acridinium Betaine as a Single-Electron-Transfer Catalyst: Design and Application to Dimerization of Oxindoles

(2017) Daisuke Uraguchi et al.   ACS Catalysis

Direct Allylic C–H Bond Activation To Synthesize [Pd(η3-cin)(IPr)Cl] Complex: Application in the Allylation of Oxindoles

(2017) Rong-Bin Hu et al.   ACS Catalysis

Phosphine-Catalyzed Asymmetric Intermolecular Cross-Vinylogous Rauhut–Currier Reactions of Vinyl Ketones with para-Quinone Methides

(2017) Shenhuan Li et al.   ACS Catalysis

Application of 7-azaisatins in enantioselective Morita–Baylis–Hillman reaction

(2016) Qing He et al.   Beilstein Journal of Organic Chemistry

Stereoselective and Regioselective Assembly of Spirooxindole [2,1-b]furan Motifs through a Tandem Friedel-Crafts Alkylation/5-exo-dig-Cyclization

(2016) Nandarapu Kumarswamyreddy et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Organocatalytic stereoselective [8+2] and [6+4] cycloadditions

(2016) Rasmus Mose et al.   Nature Chemistry

Ligand-Free Pd-Catalyzed Domino Synthesis of Carbazoles via Dehydrogenative Aromatization/C(sp2)–C(sp2) Coupling Sequence

(2016) Lixian Wen et al.   ORGANIC LETTERS

Palladium-Catalyzed Aerobic Dehydrogenation of Cyclic Hydrocarbons for the Synthesis of Substituted Aromatics and Other Unsaturated Products

(2016) Andrei V. Iosub et al.   ACS Catalysis

Therapeutic Potential of Spirooxindoles as Antiviral Agents

(2016) Na Ye et al.   ACS Infectious Diseases

Regio- and Enantioselective Aza-Diels-Alder Reactions of 3-Vinylindoles: A Concise Synthesis of the Antimalarial Spiroindolone NITD609

(2015) Haifeng Zheng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Formal Direct Cross-Coupling of Phenols with Amines

(2015) Zhengwang Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Modular Catalytic Synthesis of 3-Amino-3-aryl-2-oxindoles: Rh Catalysis with Isatin-DerivedN-Boc-Protected Ketimines

(2015) Carolina S. Marques et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Divergent Cyclization Reactions of Morita–Baylis–Hillman Carbonates of 2-Cyclohexenone and Isatylidene Malononitriles

(2015) Jing Peng et al.   ORGANIC LETTERS

Palladium-catalyzed direct β-arylation of ketones with diaryliodonium salts: a stoichiometric heavy metal-free and user-friendly approach

(2015) Zhongxing Huang et al.   Chemical Science

Highly Enantioselective Intermolecular Cross Rauhut-Currier Reaction Catalyzed by a Multifunctional Lewis Base Catalyst

(2014) Xuelin Dong et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Triple Relay Catalysis: Enantioselective Synthesis of Spirocyclic Indolines through a One-Pot Process Featuring an Asymmetric 6π Electrocyclization

(2014) Xiao-Ping Yin et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Recent progress in sodium channel modulators for pain

(2014) Sharan K. Bagal et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Organocatalytic Asymmetric Friedel-Crafts Reaction of Sesamol with Isatins: Access to Biologically Relevant 3-Aryl-3-hydroxy-2-oxindoles

(2014) Akshay Kumar et al.   Chemistry-An Asian Journal

Organocatalytic Asymmetric Assembly Reactions: Synthesis of Spirooxindoles via Organocascade Strategies

(2014) Daojuan Cheng et al.   ACS Catalysis

Recent Advances in Asymmetric Organocatalytic Construction of 3,3′-Spirocyclic Oxindoles

(2013) Liang Hong et al.   ADVANCED SYNTHESIS & CATALYSIS

Synthesis of 3,3-Disubstituted Oxindoles by Palladium-Catalyzed Asymmetric Intramolecular α-Arylation of Amides: Reaction Development and Mechanistic Studies

(2013) Dmitry Katayev et al.   CHEMISTRY-A EUROPEAN JOURNAL

Palladium-catalyzed arylation of aryl sulfonamides with cyclohexanones

(2013) Xiangxiang Cao et al.   JOURNAL OF MOLECULAR CATALYSIS A-CHEMICAL

Rauhut–Currier-Type Reaction with Morita–Baylis–Hillman Carbonates of 2-Cyclohexenone and Alkylidenemalononitriles To Access Chromene Derivatives

(2013) Jing Peng et al.   ORGANIC LETTERS

Synthesis of 3-Fluoro-3-aryl Oxindoles: Direct Enantioselective α Arylation of Amides

(2012) Linglin Wu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Me-BIPAM for the Synthesis of Optically Active 3-Aryl-3-hydroxy-2-oxindoles by Ruthenium-catalyzed Addition of Arylboronic Acids to Isatins

(2012) Yasunori Yamamoto et al.   Chemistry-An Asian Journal

Strategies for the enantioselective synthesis of spirooxindoles

(2012) Nicolas R. Ball-Jones et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Pd-Catalyzed Synthesis of Aryl Amines via Oxidative Aromatization of Cyclic Ketones and Amines with Molecular Oxygen

(2012) Simon A. Girard et al.   ORGANIC LETTERS

Organocatalytic Asymmetric α-Amination of Unprotected 3-Aryl and 3-Aliphatic Substituted Oxindoles using Di-tert-butyl Azodicarboxylate

(2011) Feng Zhou et al.   ADVANCED SYNTHESIS & CATALYSIS

Discovery of XEN907, a spirooxindole blocker of NaV1.7 for the treatment of pain

(2011) Sultan Chowdhury et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

The Palladium Catalyzed Asymmetric Addition of Oxindoles and Allenes: An Atom-Economical Versatile Method for the Construction of Chiral Indole Alkaloids

(2011) Barry M. Trost et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Selective Modulation of Gq/Gs pathways by Naphtho Pyrano Pyrimidines As Antagonists of the Neuropeptide S Receptor

(2010) Joshua G. McCoy et al.   ACS Chemical Neuroscience

Design, synthesis and in vitro evaluation of antitubercular and antimicrobial activity of some novel pyranopyrimidines

(2010) Nimesh R. Kamdar et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Spirotetrahydro β-Carbolines (Spiroindolones): A New Class of Potent and Orally Efficacious Compounds for the Treatment of Malaria

(2010) Bryan K. S. Yeung et al.   JOURNAL OF MEDICINAL CHEMISTRY

Preparation and Utility of Trihaloethyl Imidates: Useful Reagents for the Synthesis of Amidines

(2010) Stéphane Caron et al.   JOURNAL OF ORGANIC CHEMISTRY

Development of a Cysteine-Catalyzed Enantioselective Rauhut−Currier Reaction

(2010) Carrie E. Aroyan et al.   JOURNAL OF ORGANIC CHEMISTRY

Spiroindolones, a Potent Compound Class for the Treatment of Malaria

(2010) M. Rottmann et al.   SCIENCE

ortho-Acidic aromatic thiols as efficient catalysts of intramolecular Morita–Baylis–Hillman and Rauhut–Currier reactions

(2010) Philipp S. Selig et al.   TETRAHEDRON LETTERS

Catalytic Asymmetric Synthesis of Substituted 3-Hydroxy-2-Oxindoles

(2009) Nadine V. Hanhan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION