Synthesis of 3,3-Disubstituted Oxindoles by Palladium-Catalyzed Asymmetric Intramolecular α-Arylation of Amides: Reaction Development and Mechanistic Studies

Rotational Isomers of N-Methyl-N-arylacetamides and Their Derived Enolates: Implications for Asymmetric Hartwig Oxindole Cyclizations

(2013) Jérémie Mandel et al.   JOURNAL OF ORGANIC CHEMISTRY

N-Heterocyclic Carbene-Palladium(II)-1-Methylimidazole Complex Catalyzed α-Arylation of Oxindoles with Aryl Chlorides and Aerobic Oxidation of the Products in a One-Pot Procedure

(2013) Zheng-Kang Xiao et al.   ORGANIC LETTERS

Scope and mechanism of asymmetric C(sp3)–H/C(Ar)–X coupling reactions: computational and experimental study

(2013) Evgeny Larionov et al.   Chemical Science

Synthesis of 3-Fluoro-3-aryl Oxindoles: Direct Enantioselective α Arylation of Amides

(2012) Linglin Wu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Enantioselective Synthesis of a 3-Aryl-3-benzyloxindole (=3-Aryl-3-benzyl-1,3-dihydro-2H-indol-2-one) Exhibiting Antitumor Activity

(2012) Dmitry Katayev et al.   HELVETICA CHIMICA ACTA

Chiral N-Heterocyclic Carbene Borane Complexes: Synthesis and Structural Analysis

(2012) Dipshikha Banerjee et al.   ORGANOMETALLICS

Chiral N-Heterocyclic Carbene Gold Complexes: Synthesis, Properties, and Application in Asymmetric Catalysis

(2012) Dipshikha Banerjee et al.   ORGANOMETALLICS

Six-Membered, Chiral NHCs Derived from Camphor: Structure–Reactivity Relationship in Asymmetric Oxindole Synthesis

(2012) Markus J. Spallek et al.   ORGANOMETALLICS

Asymmetric C(sp3)-H/C(Ar) coupling reactions. Highly enantio-enriched indolines via regiodivergent reaction of a racemic mixture

(2012) Dmitry Katayev et al.   Chemical Science

Fused Indolines by Palladium-Catalyzed Asymmetric CC Coupling Involving an Unactivated Methylene Group

(2011) Masafumi Nakanishi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Transition-Metal-Mediated Routes to 3,3-Disubstituted Oxindoles through Anilide Cyclisation

(2011) Johannes E. M. N. Klein et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Synthesis of ChiralN-Heterocyclic Carbene Ligands with Rigid Backbones and Application to the Palladium-Catalyzed Enantioselective Intramolecular α-Arylation of Amides

(2011) Lantao Liu et al.   ORGANIC LETTERS

Facile Creation of 3-Indolyl-3-hydroxy-2-oxindoles by an Organocatalytic Enantioselective Friedel-Crafts Reaction of Indoles with Isatins

(2010) Jing Deng et al.   ADVANCED SYNTHESIS & CATALYSIS

Catalytic Asymmetric Synthesis of Oxindoles Bearing a Tetrasubstituted Stereocenter at the C-3 Position

(2010) Feng Zhou et al.   ADVANCED SYNTHESIS & CATALYSIS

Asymmetric Michael Addition Reaction of 3-Substituted Oxindoles to Nitroolefins Catalyzed by a Chiral Alkyl- Substituted Thiourea Catalyst

(2010) Xin Li et al.   ADVANCED SYNTHESIS & CATALYSIS

New Chiral N-Heterocyclic Carbene Ligands in Palladium-Catalyzed α-Arylations of Amides: Conformational Locking through Allylic Strain as a Device for Stereocontrol

(2010) Yi-Xia Jia et al.   CHEMISTRY-A EUROPEAN JOURNAL

Catalytic Asymmetric Synthesis of 3-(α-Hydroxy-β-carbonyl) Oxindoles by a ScIII-Catalyzed Direct Aldol-Type Reaction

(2010) Ke Shen et al.   CHEMISTRY-A EUROPEAN JOURNAL

Chiral Scandium-Catalyzed Enantioselective Hydroxymethylation of Ketones in Water

(2010) Shū Kobayashi et al.   Chemistry-An Asian Journal

Catalytic Asymmetric Synthesis of 3-Aminooxindoles: Enantiofacial Selectivity Switch in Bimetallic vs Monometallic Schiff Base Catalysis

(2010) Shinsuke Mouri et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Highly Chemo- and Enantioselective Synthesis of 3-Allyl-3-aryl Oxindoles via the Direct Palladium-Catalyzed α-Arylation of Amides

(2010) Xinjun Luan et al.   ORGANIC LETTERS

Enantioselective Allylation, Crotylation, and Reverse Prenylation of Substituted Isatins: Iridium-Catalyzed CC Bond-Forming Transfer Hydrogenation

(2009) Junji Itoh et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Asymmetric Synthesis of Substituted 3-Hydroxy-2-Oxindoles

(2009) Nadine V. Hanhan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Phosphonium Salts as Chiral Phase-Transfer Catalysts: Asymmetric Michael and Mannich Reactions of 3-Aryloxindoles

(2009) Rongjun He et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric construction of quaternary stereocenters by direct organocatalytic amination of 3-substituted oxindoles

(2009) Zi-Qing Qian et al.   CHEMICAL COMMUNICATIONS

Organocatalytic asymmetric allylic alkylation of oxindoles with Morita–Baylis–Hillman carbonates

(2009) Kun Jiang et al.   CHEMICAL COMMUNICATIONS

Asymmetric Iminium Ion Catalysis with a Novel Bifunctional Primary Amine Thiourea: Controlling Adjacent Quaternary and Tertiary Stereocenters

(2009) Patrizia Galzerano et al.   CHEMISTRY-A EUROPEAN JOURNAL

Catalytic Double Stereoinduction in Asymmetric Allylic Alkylation of Oxindoles

(2009) Barry M. Trost et al.   CHEMISTRY-A EUROPEAN JOURNAL

Organocatalytic Enantioselective Cross-Aldol Reactions of Aldehydes with Isatins: Formation of Two Contiguous Quaternary Centered 3-Substituted 3-Hydroxyindol-2-ones

(2009) Fei Xue et al.   Chemistry-An Asian Journal

Expanding the Scope of Cinchona Alkaloid-Catalyzed Enantioselective α-Aminations of Oxindoles: A Versatile Approach to Optically Active 3-Amino-2-oxindole Derivatives

(2009) Tommy Bui et al.   JOURNAL OF ORGANIC CHEMISTRY

Enantioselective Organocatalyticanti-Mannich-Type Reaction ofN-Unprotected 3-Substituted 2-Oxindoles with AromaticN-Ts-aldimines

(2009) Liang Cheng et al.   JOURNAL OF ORGANIC CHEMISTRY

Palladium-Catalyzed Enantioselective α-Arylation and α-Vinylation of Oxindoles Facilitated by an Axially Chiral P-Stereogenic Ligand

(2009) Alexander M. Taylor et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Base-Free Phase-Transfer Reaction in Water-Rich Solvent

(2009) Rongjun He et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IBiox[(−)-menthyl]: A Sterically Demanding Chiral NHC Ligand

(2009) Sebastian Würtz et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

C−C Reductive Elimination in Palladium Complexes, and the Role of Coupling Additives. A DFT Study Supported by Experiment

(2009) Martín Pérez-Rodríguez et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Synthesis of SM-130686 Based on the Development of Asymmetric Cu(I)F Catalysis To Access 2-Oxindoles Containing a Tetrasubstituted Carbon

(2009) Daisuke Tomita et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Thiourea-Catalyzed Highly Enantio- and Diastereoselective Additions of Oxindoles to Nitroolefins: Application to the Formal Synthesis of (+)-Physostigmine

(2009) Tommy Bui et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Homodinuclear Mn(III)2−Schiff Base Complex for Catalytic Asymmetric 1,4-Additions of Oxindoles to Nitroalkenes

(2009) Yuko Kato et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric Michael addition reaction of 3-substituted-N-Boc oxindoles to activated terminal alkenes catalyzed by a bifunctional tertiary-amine thiourea catalyst

(2009) Xin Li et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Asymmetric Aldol Reaction of Acetaldehyde and Isatin Derivatives for the Total Syntheses ofent-Convolutamydine E and CPC-1 and a Half Fragment of Madindoline A and B

(2009) Takahiko Itoh et al.   ORGANIC LETTERS

Highly Enantioselective and Organocatalytic α-Amination of 2-Oxindoles

(2009) Liang Cheng et al.   ORGANIC LETTERS

Asymmetric Syntheses of Oxindole and Indole Spirocyclic Alkaloid Natural Products

(2009) Barry Trost et al.   SYNTHESIS-STUTTGART

Organocatalytic Reactions with Acetaldehyde

(2008) Benito Alcaide et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cinchona Alkaloid Catalyzed Enantioselective Fluorination of Allyl Silanes, Silyl Enol Ethers, and Oxindoles

(2008) Takehisa Ishimaru et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chiral N-heterocyclic carbene ligands for asymmetric catalytic oxindole synthesis

(2008) Yi-Xia Jia et al.   CHEMICAL COMMUNICATIONS

Enantioselective Synthesis of (R)-Convolutamydine A with NewN-Heteroarylsulfonylprolinamides

(2008) Shuichi Nakamura et al.   CHEMISTRY-A EUROPEAN JOURNAL

Design, Synthesis, and SAR of New Pyrrole-Oxindole Progesterone Receptor Modulators Leading to 5-(7-Fluoro-3,3-dimethyl-2-oxo-2,3-dihydro-1H-indol-5-yl)-1-methyl-1H-pyrrole-2-carbonitrile (WAY-255348)

(2008) Andrew Fensome et al.   JOURNAL OF MEDICINAL CHEMISTRY

Direct Catalytic Asymmetric Synthesis of Cyclic Aminals from Aldehydes

(2008) Xu Cheng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Organocatalytic Stereoselective Mannich Reaction of 3-Substituted Oxindoles

(2008) Xu Tian et al.   ORGANIC LETTERS

Matching the Chirality of Monodentate N-Heterocyclic Carbene Ligands: A Case Study on Well-Defined Palladium Complexes for the Asymmetric α-Arylation of Amides

(2008) Xinjun Luan et al.   ORGANIC LETTERS

Catalytic Asymmetric Hydroxylation of Oxindoles by Molecular Oxygen Using a Phase-Transfer Catalyst

(2008) Daisuke Sano et al.   ORGANIC LETTERS