Synthetic Biology Approaches to Engineer Saccharomyces cerevisiae towards the Industrial Production of Valuable Polyphenolic Compounds

Engineering Saccharomyces cerevisiae Coculture Platform for the Production of Flavonoids

(2020) Yun Du et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

A Combinatorial Approach to Optimize the Production of Curcuminoids From Tyrosine in Escherichia coli

(2020) Joana L. Rodrigues et al.   Frontiers in Bioengineering and Biotechnology

A review on anti-cancer properties of Quercetin in breast cancer

(2020) Maryam Ezzati et al.   LIFE SCIENCES

De Novo Biosynthesis of Caffeic Acid from Glucose by Engineered Saccharomyces cerevisiae

(2020) Yuanzi Li et al.   ACS Synthetic Biology

Engineering the Biosynthesis of Caffeic Acid in Saccharomyces cerevisiae with Heterologous Enzyme Combinations

(2019) Lanqing Liu et al.   Engineering

A Review of Curcumin and Its Derivatives as Anticancer Agents

(2019) Mhd Tomeh et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Antioxidant effect of resveratrol in single red blood cells measured by thermal fluctuation spectroscopy

(2019) María José Gallardo et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Anti-cancer effects of polyphenols via targeting p53 signaling pathway: updates and future directions

(2019) Haroon Khan et al.   BIOTECHNOLOGY ADVANCES

Metabolic Engineering of Saccharomyces cerevisiae for De Novo Production of Kaempferol

(2019) Xiaomei Lyu et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Toward Developing a Yeast Cell Factory for the Production of Prenylated Flavonoids

(2019) Mark Levisson et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

A review of the current evidence of fruit phenolic compounds as potential antimicrobials against pathogenic bacteria

(2019) M.C. Lima et al.   MICROBIAL PATHOGENESIS

Elucidation of the biosynthesis pathway and heterologous construction of a sustainable route for producing umbelliferone

(2019) Yucheng Zhao et al.   Journal of Biological Engineering

A review of molecular mechanisms involved in anticancer and antiangiogenic effects of natural polyphenolic compounds

(2019) Hassan Abbaszadeh et al.   PHYTOTHERAPY RESEARCH

Genistein Has Antiviral Activity against Herpes B Virus and Acts Synergistically with Antiviral Treatments to Reduce Effective Dose

(2019) Julia C. LeCher et al.   Viruses-Basel

De novo biosynthesis of liquiritin in Saccharomyces cerevisiae

(2019) Yan Yin et al.   Acta Pharmaceutica Sinica B

Energy and Enzyme Activity Landscapes of Yeast Chorismate Mutase at Cellular Concentrations of Allosteric Effectors

(2019) Scott D. Gorman et al.   BIOCHEMISTRY

Formation of Flavonoid Metabolons: Functional Significance of Protein-Protein Interactions and Impact on Flavonoid Chemodiversity

(2019) Toru Nakayama et al.   Frontiers in Plant Science

Metabolic engineering and transcriptomic analysis of Saccharomyces cerevisiae producing p-coumaric acid from xylose

(2019) Gheorghe M. Borja et al.   Microbial Cell Factories

Rewiring carbon metabolism in yeast for high level production of aromatic chemicals

(2019) Quanli Liu et al.   Nature Communications

Memory and Brain Amyloid and Tau Effects of a Bioavailable Form of Curcumin in Non-Demented Adults: A Double-Blind, Placebo-Controlled 18-Month Trial

(2018) Gary W. Small et al.   AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY

Natural Polyphenols: Biological Activity, Pharmacological Potential, Means of Metabolic Engineering (Review)

(2018) V. V. Teplova et al.   APPLIED BIOCHEMISTRY AND MICROBIOLOGY

Plant nutraceuticals as antimicrobial agents in food preservation: terpenoids, polyphenols and thiols

(2018) Ignacio Gutiérrez-del-Río et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Engineering de novo anthocyanin production in Saccharomyces cerevisiae

(2018) Mark Levisson et al.   Microbial Cell Factories

Response of Plant Secondary Metabolites to Environmental Factors

(2018) et al.   MOLECULES

Rutin as a Potent Antioxidant: Implications for Neurodegenerative Disorders

(2018) Adaze Bijou Enogieru et al.   Oxidative Medicine and Cellular Longevity

Screening Phosphorylation Site Mutations in Yeast Acetyl-CoA Carboxylase Using Malonyl-CoA Sensor to Improve Malonyl-CoA-Derived Product

(2018) Xiaoxu Chen et al.   Frontiers in Microbiology

Naringenin inhibited migration and invasion of glioblastoma cells through multiple mechanisms

(2018) Yen-Yu Chen et al.   ENVIRONMENTAL TOXICOLOGY

Synergistic anticancer action of quercetin and curcumin against triple-negative breast cancer cell lines

(2018) Sai Kundur et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Enhancement of Naringenin Biosynthesis from Tyrosine by Metabolic Engineering of Saccharomyces cerevisiae

(2017) Xiaomei Lyu et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Resveratrol regulates neuro-inflammation and induces adaptive immunity in Alzheimer’s disease

(2017) Charbel Moussa et al.   Journal of Neuroinflammation

Metabolic engineering of Saccharomyces cerevisiae for de novo production of dihydrochalcones with known antioxidant, antidiabetic, and sweet tasting properties

(2017) Michael Eichenberger et al.   METABOLIC ENGINEERING

Comparison of the metabolic response to over-production of p -coumaric acid in two yeast strains

(2017) Angelica Rodriguez et al.   METABOLIC ENGINEERING

Biosynthesis and engineering of kaempferol in Saccharomyces cerevisiae

(2017) Lijin Duan et al.   Microbial Cell Factories

Saccharomyces cerevisiae Shuttle vectors

(2017) Robert Gnügge et al.   YEAST

Increasing Malonyl-CoA Derived Product through Controlling the Transcription Regulators of Phospholipid Synthesis in Saccharomyces cerevisiae

(2017) Xiaoxu Chen et al.   ACS Synthetic Biology

Antiviral properties of resveratrol against pseudorabies virus are associated with the inhibition of IκB kinase activation

(2017) Xinghong Zhao et al.   Scientific Reports

Engineering Cellular Metabolism

(2016) Jens Nielsen et al.   CELL

Microbial production of value-added nutraceuticals

(2016) Jian Wang et al.   CURRENT OPINION IN BIOTECHNOLOGY

A highly efficient single-step, markerless strategy for multi-copy chromosomal integration of large biochemical pathways in Saccharomyces cerevisiae

(2016) Shuobo Shi et al.   METABOLIC ENGINEERING

Naringenin reduces inflammatory pain in mice

(2016) Felipe A. Pinho-Ribeiro et al.   NEUROPHARMACOLOGY

Dual regulation of cytoplasmic and mitochondrial acetyl-CoA utilization for improved isoprene production in Saccharomyces cerevisiae

(2016) Xiaomei Lv et al.   Nature Communications

Engineering yeast for high-level production of stilbenoid antioxidants

(2016) Mingji Li et al.   Scientific Reports

Evaluation of the bioactive properties of avenanthramide analogs produced in recombinant yeast

(2015) Andrea Moglia et al.   BIOFACTORS

Antioxidant and anti-inflammatory effects of curcuminoid-piperine combination in subjects with metabolic syndrome: A randomized controlled trial and an updated meta-analysis

(2015) Yunes Panahi et al.   CLINICAL NUTRITION

Establishment of a yeast platform strain for production of p- coumaric acid through metabolic engineering of aromatic amino acid biosynthesis

(2015) Angelica Rodriguez et al.   METABOLIC ENGINEERING

De novo production of resveratrol from glucose or ethanol by engineered Saccharomyces cerevisiae

(2015) Mingji Li et al.   METABOLIC ENGINEERING

Heterologous Production of Curcuminoids

(2015) J. L. Rodrigues et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Pterostilbene production by microorganisms expressing resveratrol O-methyltransferase

(2014) Yechun Wang et al.   ANNALS OF MICROBIOLOGY

Improving Production of Malonyl Coenzyme A-Derived Metabolites by Abolishing Snf1-Dependent Regulation of Acc1

(2014) S. Shi et al.   mBio

Combinatorial Assembly of Large Biochemical Pathways into Yeast Chromosomes for Improved Production of Value-added Compounds

(2014) Jifeng Yuan et al.   ACS Synthetic Biology

Effects and mechanisms of 8-prenylnaringenin on osteoblast MC3T3-E1 and osteoclast-like cells RAW264.7

(2014) Dan Luo et al.   Food Science & Nutrition

Genome engineering in Saccharomyces cerevisiae using CRISPR-Cas systems

(2013) James E. DiCarlo et al.   NUCLEIC ACIDS RESEARCH

Production of resveratrol from tyrosine in metabolically engineered Saccharomyces cerevisiae

(2012) So-Yeon Shin et al.   ENZYME AND MICROBIAL TECHNOLOGY

Characterization of plasmid burden and copy number inSaccharomyces cerevisiaefor optimization of metabolic engineering applications

(2012) Ashty S. Karim et al.   FEMS YEAST RESEARCH

Type III polyketide synthases in natural product biosynthesis

(2012) Dayu Yu et al.   IUBMB LIFE

De novo production of the flavonoid naringenin in engineered Saccharomyces cerevisiae

(2012) Frank Koopman et al.   Microbial Cell Factories

Upregulation of p53 Expression in Patients with Colorectal Cancer by Administration of Curcumin

(2011) Zhen-Yu He et al.   CANCER INVESTIGATION

Synthetic scaffolds increased resveratrol biosynthesis in engineered yeast cells

(2011) Yechun Wang et al.   JOURNAL OF BIOTECHNOLOGY

Harnessing yeast subcellular compartments for the production of plant terpenoids

(2011) Moran Farhi et al.   METABOLIC ENGINEERING

Stepwise increase of resveratrol biosynthesis in yeast Saccharomyces cerevisiae by metabolic engineering

(2011) Yechun Wang et al.   METABOLIC ENGINEERING

Recent advances towards development and commercialization of plant cell culture processes for the synthesis of biomolecules

(2011) Sarah A. Wilson et al.   PLANT BIOTECHNOLOGY JOURNAL

Considerable Increase in Resveratrol Production by Recombinant Industrial Yeast Strains with Use of Rich Medium

(2010) T. Sydor et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Production of resveratrol from p-coumaric acid in recombinant Saccharomyces cerevisiae expressing 4-coumarate:coenzyme A ligase and stilbene synthase genes

(2010) So-Yeon Shin et al.   ENZYME AND MICROBIAL TECHNOLOGY

Antioxidant activities of leaf extract of Salvia miltiorrhiza Bunge and related phenolic constituents

(2010) Yuan Zhang et al.   FOOD AND CHEMICAL TOXICOLOGY

A randomized, double-blind, placebo-controlled, cross-over pilot study on the use of a standardized hop extract to alleviate menopausal discomforts

(2010) R. Erkkola et al.   PHYTOMEDICINE

Metabolic engineering of the complete pathway leading to heterologous biosynthesis of various flavonoids and stilbenoids in Saccharomyces cerevisiae

(2009) Emmanouil Trantas et al.   METABOLIC ENGINEERING