Curses or Cures: A Review of the Numerous Benefits Versus the Biosecurity Concerns of Conotoxin Research
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Title
Curses or Cures: A Review of the Numerous Benefits Versus the Biosecurity Concerns of Conotoxin Research
Authors
Keywords
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Journal
Biomedicines
Volume 8, Issue 8, Pages 235
Publisher
MDPI AG
Online
2020-07-23
DOI
10.3390/biomedicines8080235
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Note: Only part of the references are listed.- A structurally minimized yet fully active insulin based on cone-snail venom insulin principles
- (2020) Xiaochun Xiong et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
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- (2019) Veronika Grau et al. Frontiers in Pharmacology
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- (2019) Dan Li et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Development of a high-throughput fluorescent no-wash sodium influx assay
- (2019) Bryan Tay et al. PLoS One
- [Ca 2+ ] changes in sympathetic varicosities and Schwann cells in rat mesenteric arteries—Relation to noradrenaline release and contraction
- (2019) Thomas Hansen et al. Acta Physiologica
- The three-dimensional structure of an H-superfamily conotoxin reveals a granulin fold arising from a common ICK cysteine framework
- (2019) Lau D. Nielsen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Fish-hunting cone snail venoms are a rich source of minimized ligands of the vertebrate insulin receptor
- (2019) Peter Ahorukomeye et al. eLife
- Inhibition of T-Type calcium channels in mEC layer II stellate neurons reduces neuronal hyperexcitability associated with epilepsy
- (2019) Aradhya Nigam et al. EPILEPSY RESEARCH
- Ca2+-independent but voltage-dependent quantal catecholamine secretion (CiVDS) in the mammalian sympathetic nervous system
- (2019) Rong Huang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Brain-derived neurotrophic factor stimulation of T-type Ca2+ channels in sensory neurons contributes to increased peripheral pain sensitivity
- (2019) Hua Wang et al. Science Signaling
- Peptide therapeutics from venom: Current status and potential
- (2018) Michael W. Pennington et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Pain therapeutics from cone snail venoms: From Ziconotide to novel non-opioid pathways
- (2018) Helena Safavi-Hemami et al. Journal of Proteomics
- Targeted Sequencing of Venom Genes from Cone Snail Genomes Improves Understanding of Conotoxin Molecular Evolution
- (2018) Mark A Phuong et al. MOLECULAR BIOLOGY AND EVOLUTION
- Exon-capture based phylogeny and diversification of the venomous gastropods (Neogastropoda, Conoidea)
- (2018) J Abdelkrim et al. MOLECULAR BIOLOGY AND EVOLUTION
- Phosphocholine-Modified Lipooligosaccharides of Haemophilus influenzae Inhibit ATP-Induced IL-1β Release by Pulmonary Epithelial Cells
- (2018) Katrin Richter et al. MOLECULES
- C-Reactive Protein Stimulates Nicotinic Acetylcholine Receptors to Control ATP-Mediated Monocytic Inflammasome Activation
- (2018) Katrin Richter et al. Frontiers in Immunology
- Conotoxin κM-RIIIJ, a tool targeting asymmetric heteromeric Kv1 channels
- (2018) Sönke Cordeiro et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Discovery of Novel Conotoxin Candidates Using Machine Learning
- (2018) Qing Li et al. Toxins
- Conus Envenomation of Humans: In Fact and Fiction
- (2018) Alan Kohn Toxins
- Gene design, fusion technology and TEV cleavage conditions influence the purification of oxidized disulphide-rich venom peptides in Escherichia coli
- (2017) Ana Filipa Sequeira et al. Microbial Cell Factories
- High-throughput expression of animal venom toxins in Escherichia coli to generate a large library of oxidized disulphide-reticulated peptides for drug discovery
- (2017) Jeremy Turchetto et al. Microbial Cell Factories
- The Polyanalgesic Consensus Conference (PACC): Recommendations on Intrathecal Drug Infusion Systems Best Practices and Guidelines
- (2017) Timothy R. Deer et al. NEUROMODULATION
- Venom peptides as pharmacological tools and therapeutics for diabetes
- (2017) Samuel D. Robinson et al. NEUROPHARMACOLOGY
- α-Conotoxins to explore the molecular, physiological and pathophysiological functions of neuronal nicotinic acetylcholine receptors
- (2017) Julien Giribaldi et al. NEUROSCIENCE LETTERS
- Sensitive Detection of α-Conotoxin GI in Human Plasma Using a Solid-Phase Extraction Column and LC-MS/MS
- (2017) Shuo Yu et al. Toxins
- Snake Venom PLA2, a Promising Target for Broad-Spectrum Antivenom Drug Development
- (2017) Huixiang Xiao et al. Biomed Research International
- Efficient functional neutralization of lethal peptide toxins in vivo by oligonucleotides
- (2017) Tarek Mohamed Abd El-Aziz et al. Scientific Reports
- Age-related association of venom gene expression and diet of predatory gastropods
- (2016) Dan Chang et al. BMC EVOLUTIONARY BIOLOGY
- Dietary breadth is positively correlated with venom complexity in cone snails
- (2016) Mark A. Phuong et al. BMC GENOMICS
- Nicotinic receptor involvement in regulation of functions of mouse neutrophils from inflammatory site
- (2016) Valentina G. Safronova et al. IMMUNOBIOLOGY
- Venom Insulins of Cone Snails Diversify Rapidly and Track Prey Taxa
- (2016) Helena Safavi-Hemami et al. MOLECULAR BIOLOGY AND EVOLUTION
- Postsynaptic, not presynaptic NMDA receptors are required for spike-timing-dependent LTD induction
- (2016) Brett C Carter et al. NATURE NEUROSCIENCE
- A minimized human insulin-receptor-binding motif revealed in a Conus geographus venom insulin
- (2016) John G Menting et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Rapid expansion of the protein disulfide isomerase gene family facilitates the folding of venom peptides
- (2016) Helena Safavi-Hemami et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A minimized human insulin-receptor-binding motif revealed in a Conus geographus venom insulin
- (2016) John G Menting et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- The use of α-conotoxin ImI to actualize the targeted delivery of paclitaxel micelles to α7 nAChR-overexpressing breast cancer
- (2015) Dong Mei et al. BIOMATERIALS
- Prey-Capture Strategies of Fish-Hunting Cone Snails: Behavior, Neurobiology and Evolution
- (2015) Baldomero M. Olivera et al. BRAIN BEHAVIOR AND EVOLUTION
- Peptide therapeutics: current status and future directions
- (2015) Keld Fosgerau et al. DRUG DISCOVERY TODAY
- Inhibition of cholinergic pathways in Drosophila melanogaster by α-conotoxins
- (2015) Mari D. Heghinian et al. FASEB JOURNAL
- Zebrafish as tools for drug discovery
- (2015) Calum A. MacRae et al. NATURE REVIEWS DRUG DISCOVERY
- Small Molecules in the Cone Snail Arsenal
- (2015) Jorge L. B. Neves et al. ORGANIC LETTERS
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- (2015) Lynn R. Webster PAIN MEDICINE
- Specialized insulin is used for chemical warfare by fish-hunting cone snails
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- (2015) Senanayake A.M. Kularatne et al. TOXICON
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- (2015) Ernesto Ortiz et al. TOXICON
- Strategic Approaches to Optimizing Peptide ADME Properties
- (2014) Li Di AAPS Journal
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- (2014) N. Puillandre et al. JOURNAL OF MOLLUSCAN STUDIES
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- X-ray structures of AMPA receptor-cone snail toxin complexes illuminate activation mechanism
- (2014) L. Chen et al. SCIENCE
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- (2014) Y. Zhang et al. Science Signaling
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- (2013) C. Petrel et al. BIOCHEMICAL PHARMACOLOGY
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- (2012) Philippe Favreau et al. BRITISH JOURNAL OF PHARMACOLOGY
- Conotoxins: Review and Docking Studies to determine potentials of Conotoxin as an Anticancer Drug Molecule
- (2012) Kirtan Dave et al. CURRENT TOPICS IN MEDICINAL CHEMISTRY
- Bleeding risk and safety profile related to the use of eptifibatide: a current review
- (2012) Fadi Saab et al. Expert Opinion On Drug Safety
- Molecular Phylogeny, Classification and Evolution of Conopeptides
- (2012) N. Puillandre et al. JOURNAL OF MOLECULAR EVOLUTION
- Extensive and Continuous Duplication Facilitates Rapid Evolution and Diversification of Gene Families
- (2012) Dan Chang et al. MOLECULAR BIOLOGY AND EVOLUTION
- Characterization of two neuronal subclasses through constellation pharmacology
- (2012) R. W. Teichert et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Functional profiling of neurons through cellular neuropharmacology
- (2012) R. W. Teichert et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The long road of research on snake venom serine proteinases
- (2012) Solange M.T. Serrano TOXICON
- Venoms as a platform for human drugs: translating toxins into therapeutics
- (2011) Glenn F King EXPERT OPINION ON BIOLOGICAL THERAPY
- Nicotine-Mediated Activation of Dopaminergic Neurons in Distinct Regions of the Ventral Tegmental Area
- (2011) Rubing Zhao-Shea et al. NEUROPSYCHOPHARMACOLOGY
- The Engineering of an Orally Active Conotoxin for the Treatment of Neuropathic Pain
- (2010) Richard J. Clark et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Guidelines for treatment of autoimmune neuromuscular transmission disorders
- (2010) G. O. Skeie et al. EUROPEAN JOURNAL OF NEUROLOGY
- Biochemical Characterization of κM-RIIIJ, a Kv1.2 Channel Blocker
- (2010) Ping Chen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Identification ofConusPeptidylprolyl Cis-Trans Isomerases (PPIases) and Assessment of Their Role in the Oxidative Folding of Conotoxins
- (2010) Helena Safavi-Hemami et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Evolution of Conus Peptide Genes: Duplication and Positive Selection in the A-Superfamily
- (2010) Nicolas Puillandre et al. JOURNAL OF MOLECULAR EVOLUTION
- Neuronal circuitry for pain processing in the dorsal horn
- (2010) Andrew J. Todd NATURE REVIEWS NEUROSCIENCE
- Studies on marine toxins: chemical and biological aspects
- (2010) Valentin A Stonik et al. RUSSIAN CHEMICAL REVIEWS
- Alpha-conotoxins as pharmacological probes of nicotinic acetylcholine receptors
- (2009) Layla Azam et al. ACTA PHARMACOLOGICA SINICA
- Alpha9 nicotinic acetylcholine receptors and the treatment of pain
- (2009) J. Michael McIntosh et al. BIOCHEMICAL PHARMACOLOGY
- A Novel Conus Snail Polypeptide Causes Excitotoxicity by Blocking Desensitization of AMPA Receptors
- (2009) Craig S. Walker et al. CURRENT BIOLOGY
- Epidemiology of scorpionism: A global appraisal
- (2008) J.-P. Chippaux et al. ACTA TROPICA
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