Changes in Plasma Itaconate Elevation in Early Rheumatoid Arthritis Patients Elucidates Disease Activity Associated Macrophage Activation

Electrophilic properties of itaconate and derivatives regulate the IκBζ–ATF3 inflammatory axis

(2018) Monika Bambouskova et al.   NATURE

Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1

(2018) Evanna L. Mills et al.   NATURE

Targeting ultrasound remission in early rheumatoid arthritis: the results of the TaSER study, a randomised clinical trial

(2016) James Dale et al.   ANNALS OF THE RHEUMATIC DISEASES

Variations in the metabolome in response to disease activity of rheumatoid arthritis

(2016) Zuzana Tatar et al.   BMC MUSCULOSKELETAL DISORDERS

Food Fight: Role of Itaconate and Other Metabolites in Antimicrobial Defense

(2016) Harding H. Luan et al.   Cell Metabolism

Itaconate Links Inhibition of Succinate Dehydrogenase with Macrophage Metabolic Remodeling and Regulation of Inflammation

(2016) Vicky Lampropoulou et al.   Cell Metabolism

Targeted Metabolic Profiling of the Tg197 Mouse Model Reveals Itaconic Acid as a Marker of Rheumatoid Arthritis

(2016) Filippos Michopoulos et al.   JOURNAL OF PROTEOME RESEARCH

Metabolomics in rheumatic diseases: desperately seeking biomarkers

(2016) Monica Guma et al.   Nature Reviews Rheumatology

Topic modeling for untargeted substructure exploration in metabolomics

(2016) Justin Johan Jozias van der Hooft et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNA-155 regulates monocyte chemokine and chemokine receptor expression in Rheumatoid Arthritis

(2016) Aziza Elmesmari et al.   RHEUMATOLOGY

Exploring the Inflammatory Metabolomic Profile to Predict Response to TNF-α Inhibitors in Rheumatoid Arthritis

(2016) Bart V. J. Cuppen et al.   PLoS One

Metabolomics for rheumatic diseases: has the time come?

(2015) Luca Semerano et al.   ANNALS OF THE RHEUMATIC DISEASES

Metabolomics to identify biomarkers and as a predictive tool in inflammatory diseases

(2015) Gurpreet Singh Jutley et al.   BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY

Metabolomics in rheumatology

(2015) Sabrina R. Kapoor et al.   RHEUMATOLOGY

Inborn Errors of Metabolism

(2015) Hilary J. Vernon   JAMA Pediatrics

Metabolic Profiling Predicts Response to Anti-Tumor Necrosis Factor α Therapy in Patients With Rheumatoid Arthritis

(2013) Sabrina R. Kapoor et al.   ARTHRITIS AND RHEUMATISM

The Impact of Inflammation on Metabolomic Profiles in Patients With Arthritis

(2013) Stephen P. Young et al.   ARTHRITIS AND RHEUMATISM

Metabolomics in rheumatic diseases: The potential of an emerging methodology for improved patient diagnosis, prognosis, and treatment efficacy

(2013) Roberta Priori et al.   AUTOIMMUNITY REVIEWS

Serum Metabolic Signatures of Four Types of Human Arthritis

(2013) Miao Jiang et al.   JOURNAL OF PROTEOME RESEARCH

Tightening Up? Impact of Musculoskeletal Ultrasound Disease Activity Assessment on Early Rheumatoid Arthritis Patients Treated Using a Treat to Target Strategy

(2013) James Dale et al.   ARTHRITIS CARE & RESEARCH

Towards metabolic biomarkers of insulin resistance and type 2 diabetes: progress from the metabolome

(2013) Lee D Roberts et al.   Lancet Diabetes & Endocrinology

IDEOM: an Excel interface for analysis of LC–MS-based metabolomics data

(2012) Darren J. Creek et al.   BIOINFORMATICS

1H NMR-based metabolomic analysis for identifying serum biomarkers to evaluate methotrexate treatment in patients with early rheumatoid arthritis

(2012) ZHIGANG WANG et al.   Experimental and Therapeutic Medicine

PeakML/mzMatch: A File Format, Java Library, R Library, and Tool-Chain for Mass Spectrometry Data Analysis

(2011) Richard A. Scheltema et al.   ANALYTICAL CHEMISTRY

Toward Global Metabolomics Analysis with Hydrophilic Interaction Liquid Chromatography–Mass Spectrometry: Improved Metabolite Identification by Retention Time Prediction

(2011) Darren J. Creek et al.   ANALYTICAL CHEMISTRY

The Pathogenesis of Rheumatoid Arthritis

(2011) Iain B. McInnes et al.   NEW ENGLAND JOURNAL OF MEDICINE

Diagnostic properties of metabolic perturbations in rheumatoid arthritis

(2011) Rasmus K Madsen et al.   ARTHRITIS RESEARCH & THERAPY

Interferences and contaminants encountered in modern mass spectrometry

(2008) Bernd O. Keller et al.   ANALYTICA CHIMICA ACTA

Cigarette smoking significantly increases basal metabolic rate in patients with rheumatoid arthritis

(2007) G S Metsios et al.   ANNALS OF THE RHEUMATIC DISEASES