Structure, Dynamics and Cellular Insight Into Novel Substrates of the Legionella pneumophila Type II Secretion System

Structure and functional analysis of the Legionella pneumophila chitinase ChiA reveals a novel mechanism of metal-dependent mucin degradation

(2020) Saima Rehman et al.   PLoS Pathogens

Study of Legionella Effector Domains Revealed Novel and Prevalent Phosphatidylinositol 3-Phosphate Binding Domains

(2019) Nimrod Nachmias et al.   INFECTION AND IMMUNITY

Molecular architecture, polar targeting and biogenesis of the Legionella Dot/Icm T4SS

(2019) Debnath Ghosal et al.   Nature Microbiology

The EMBL-EBI search and sequence analysis tools APIs in 2019

(2019) Fábio Madeira et al.   NUCLEIC ACIDS RESEARCH

Assessing the impact, genomics and evolution of type II secretion across a large, medically important genus: the Legionella type II secretion paradigm

(2019) Richard C. White et al.   Microbial Genomics

Type II Secretion Promotes Bacterial Growth within the Legionella-Containing Vacuole in Infected Amoebae

(2019) Richard C. White et al.   INFECTION AND IMMUNITY

Crystal structure of a hypothetical T2SS effector Lpg0189 from Legionella pneumophila reveals a novel protein fold

(2019) Xiaofang Chen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Type II Secretion-Dependent Aminopeptidase LapA and Acyltransferase PlaC Are Redundant for Nutrient Acquisition during Legionella pneumophila Intracellular Infection of Amoebas

(2018) Richard C. White et al.   mBio

The Toolbox for Uncovering the Functions of Legionella Dot/Icm Type IVb Secretion System Effectors: Current State and Future Directions

(2018) Gunnar N. Schroeder   Frontiers in Cellular and Infection Microbiology

Structural characterization of the hypothetical protein Lpg2622, a new member of the C1 family peptidases from Legionella pneumophila

(2018) Xiaojian Gong et al.   FEBS LETTERS

Crystal structure of lpg1832, a VirK family protein from Legionella pneumophila , reveals a novel fold for bacterial VirK proteins

(2017) Nannan Zhang et al.   FEBS LETTERS

Crystal Structure and Biochemical Characterization of an Aminopeptidase LapB from Legionella pneumophila

(2017) Nannan Zhang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

The trans-envelope architecture and function of the type 2 secretion system: new insights raising new questions

(2017) Jenny-Lee Thomassin et al.   MOLECULAR MICROBIOLOGY

Type II Secretion Substrates of Legionella pneumophila Translocate Out of the Pathogen-Occupied Vacuole via a Semipermeable Membrane

(2017) Hilary K. Truchan et al.   mBio

ATSAS 2.8: a comprehensive data analysis suite for small-angle scattering from macromolecular solutions

(2017) D. Franke et al.   JOURNAL OF APPLIED CRYSTALLOGRAPHY

Moenomycin Biosynthesis: Structure and Mechanism of Action of the Prenyltransferase MoeN5

(2016) Lilan Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Type II Secretion Is Necessary for Optimal Association of the Legionella-Containing Vacuole with Macrophage Rab1B but Enhances Intracellular Replication Mainly by Rab1B-Independent Mechanisms

(2016) Richard C. White et al.   INFECTION AND IMMUNITY

Crystal structure and tartrate inhibition of Legionella pneumophila histidine acid phosphatase

(2015) Richa Dhatwalia et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Current and Emerging Legionella Diagnostics for Laboratory and Outbreak Investigations

(2015) Jeffrey W. Mercante et al.   CLINICAL MICROBIOLOGY REVIEWS

Confirmed and Potential Sources of Legionella Reviewed

(2015) Eri van Heijnsbergen et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Structure of the Legionella Virulence Factor, SidC Reveals a Unique PI(4)P-Specific Binding Domain Essential for Its Targeting to the Bacterial Phagosome

(2015) Xi Luo et al.   PLoS Pathogens

The novel Legionella pneumophila type II secretion substrate NttC contributes to infection of amoebae Hartmannella vermiformis and Willaertia magna

(2014) J. Y. Tyson et al.   MICROBIOLOGY-SGM

Live-Cell Imaging of Phosphoinositide Dynamics and Membrane Architecture during Legionella Infection

(2014) S. Weber et al.   mBio

How good are my data and what is the resolution?

(2013) Philip R. Evans et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Phosphatidylinositol 3,5-bisphosphate: Low abundance, high significance

(2013) Amber J. McCartney et al.   BIOESSAYS

Multiple Legionella pneumophila Type II Secretion Substrates, Including a Novel Protein, Contribute to Differential Infection of the Amoebae Acanthamoeba castellanii, Hartmannella vermiformis, and Naegleria lovaniensis

(2013) Jessica Y. Tyson et al.   INFECTION AND IMMUNITY

Structural Basis for the Interaction between the Potato Virus X Resistance Protein (Rx) and Its Cofactor Ran GTPase-activating Protein 2 (RanGAP2)

(2013) Wei Hao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Specialized Dynamical Properties of Promiscuous Residues Revealed by Simulated Conformational Ensembles

(2013) Arianna Fornili et al.   Journal of Chemical Theory and Computation

Essential Roles and Regulation of the Legionella pneumophila Collagen-Like Adhesin during Biofilm Formation

(2012) Julia Mallegol et al.   PLoS One

Structural basis for substrate recognition by a unique Legionella phosphoinositide phosphatase

(2012) F. Hsu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

REFMAC5 for the refinement of macromolecular crystal structures

(2011) Garib N. Murshudov et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Legionella pneumophila Type II Secretion Dampens the Cytokine Response of Infected Macrophages and Epithelia

(2011) Kessler McCoy-Simandle et al.   INFECTION AND IMMUNITY

Nitrophorins: Nitrite disproportionation reaction and other novel functionalities of insect heme-based nitric oxide transport proteins

(2011) Markus Knipp et al.   IUBMB LIFE

Legionella pneumophila LbtU Acts as a Novel, TonB-Independent Receptor for the Legiobactin Siderophore

(2011) C. H. Chatfield et al.   JOURNAL OF BACTERIOLOGY

The Surfactant of Legionella pneumophila Is Secreted in a TolC-Dependent Manner and Is Antagonistic toward Other Legionella Species

(2011) C. R. Stewart et al.   JOURNAL OF BACTERIOLOGY

Differential growth of Legionella pneumophila strains within a range of amoebae at various temperatures associated with in-premise plumbing

(2011) H.Y. Buse et al.   LETTERS IN APPLIED MICROBIOLOGY

Minimization of the Legionella pneumophila genome reveals chromosomal regions involved in host range expansion

(2011) T. J. O'Connor et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Anchors for Effectors: Subversion of Phosphoinositide Lipids by Legionella

(2011) Hubert Hilbi et al.   Frontiers in Microbiology

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Modulation of Host Cell Function byLegionella pneumophilaType IV Effectors

(2010) Andree Hubber et al.   Annual Review of Cell and Developmental Biology

Glucose Metabolism in Legionella pneumophila: Dependence on the Entner-Doudoroff Pathway and Connection with Intracellular Bacterial Growth

(2010) E. Harada et al.   JOURNAL OF BACTERIOLOGY

Understanding and Predicting Druggability. A High-Throughput Method for Detection of Drug Binding Sites

(2010) Peter Schmidtke et al.   JOURNAL OF MEDICINAL CHEMISTRY

Dali server: conservation mapping in 3D

(2010) Liisa Holm et al.   NUCLEIC ACIDS RESEARCH

Molecular Detection of Legionella: Moving on From mip

(2010) Stacey F. Y. Yong et al.   Frontiers in Microbiology

Fpocket: An open source platform for ligand pocket detection

(2009) Vincent Le Guilloux et al.   BMC BIOINFORMATICS

Legionella pneumophilasecretes an endoglucanase that belongs to the family-5 of glycosyl hydrolases and is dependent upon type II secretion

(2009) Meghan M. Pearce et al.   FEMS MICROBIOLOGY LETTERS

PDB_REDO: automated re-refinement of X-ray structure models in the PDB

(2009) Robbie P. Joosten et al.   JOURNAL OF APPLIED CRYSTALLOGRAPHY

The role of biofilms and protozoa inLegionellapathogenesis: implications for drinking water

(2009) H.Y. Lau et al.   JOURNAL OF APPLIED MICROBIOLOGY

Legionella, Protozoa, and Biofilms: Interactions Within Complex Microbial Systems

(2009) Michael Taylor et al.   MICROBIAL ECOLOGY

Searching protein structure databases with DaliLite v.3

(2008) L. Holm et al.   BIOINFORMATICS

Free-living freshwater amoebae differ in their susceptibility to the pathogenic bacteriumLegionella pneumophila

(2008) Rafik Dey et al.   FEMS MICROBIOLOGY LETTERS

Surface Translocation by Legionella pneumophila: a Form of Sliding Motility That Is Dependent upon Type II Protein Secretion

(2008) C. R. Stewart et al.   JOURNAL OF BACTERIOLOGY

Automated macromolecular model building for X-ray crystallography using ARP/wARP version 7

(2008) Gerrit Langer et al.   Nature Protocols