Structure and functional analysis of the Legionella pneumophila chitinase ChiA reveals a novel mechanism of metal-dependent mucin degradation

Generation of 13C-labeled MUC5AC mucin oligosaccharides for stable isotope probing of host-associated microbial communities

(2019) Clayton Evert et al.   ACS Infectious Diseases

The mucin-selective protease StcE enables molecular and functional analysis of human cancer-associated mucins

(2019) Stacy A. Malaker et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intrinsically Disordered Linkers Impart Processivity on Enzymes by Spatial Confinement of Binding Domains

(2019) Szabo et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Type II Secretion Promotes Bacterial Growth within the Legionella-Containing Vacuole in Infected Amoebae

(2019) Richard C. White et al.   INFECTION AND IMMUNITY

In vivo structure of the Legionella type II secretion system by electron cryotomography

(2019) Debnath Ghosal et al.   Nature Microbiology

Type II Secretion-Dependent Aminopeptidase LapA and Acyltransferase PlaC Are Redundant for Nutrient Acquisition during Legionella pneumophila Intracellular Infection of Amoebas

(2018) Richard C. White et al.   mBio

Sulfated vizantin suppresses mucin layer penetration dependent on the flagella motility of Pseudomonas aeruginosa PAO1

(2018) Naoki Hayashi et al.   PLoS One

N- andO-glycosylation Analysis of Human C1-inhibitor Reveals Extensive Mucin-typeO-Glycosylation

(2017) Kathrin Stavenhagen et al.   MOLECULAR & CELLULAR PROTEOMICS

Recognition of protein-linked glycans as a determinant of peptidase activity

(2017) Ilit Noach et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Type II Secretion Substrates of Legionella pneumophila Translocate Out of the Pathogen-Occupied Vacuole via a Semipermeable Membrane

(2017) Hilary K. Truchan et al.   mBio

Allosteric modulation of cardiac myosin dynamics by omecamtiv mecarbil

(2017) Shaima Hashem et al.   PLoS Computational Biology

Acquisition of C1 inhibitor by Bordetella pertussis virulence associated gene 8 results in C2 and C4 consumption away from the bacterial surface

(2017) Elise S. Hovingh et al.   PLoS Pathogens

Type II Secretion Is Necessary for Optimal Association of the Legionella-Containing Vacuole with Macrophage Rab1B but Enhances Intracellular Replication Mainly by Rab1B-Independent Mechanisms

(2016) Richard C. White et al.   INFECTION AND IMMUNITY

Probable Person-to-Person Transmission of Legionnaires’ Disease

(2016) Ana M. Correia et al.   NEW ENGLAND JOURNAL OF MEDICINE

Legionella pneumophila strain associated with the first evidence of person-to-person transmission of Legionnaires’ disease: a unique mosaic genetic backbone

(2016) Vítor Borges et al.   Scientific Reports

Confirmed and Potential Sources of Legionella Reviewed

(2015) Eri van Heijnsbergen et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Pseudomonas aeruginosainjects type III effector ExoS into epithelial cells through the function of type IV pili

(2015) Naoki Hayashi et al.   FEBS LETTERS

The Phyre2 web portal for protein modeling, prediction and analysis

(2015) Lawrence A Kelley et al.   Nature Protocols

Advanced ensemble modelling of flexible macromolecules using X-ray solution scattering

(2015) Giancarlo Tria et al.   IUCrJ

Pathogenic E. coli Exploits SslE Mucinase Activity to Translocate through the Mucosal Barrier and Get Access to Host Cells

(2015) Maria Valeri et al.   PLoS One

Helical Shape ofHelicobacter pyloriRequires an Atypical Glutamine as a Zinc Ligand in the Carboxypeptidase Csd4

(2014) Anson C. K. Chan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The novel Legionella pneumophila type II secretion substrate NttC contributes to infection of amoebae Hartmannella vermiformis and Willaertia magna

(2014) J. Y. Tyson et al.   MICROBIOLOGY-SGM

The Vibrio cholerae Extracellular Chitinase ChiA2 Is Important for Survival and Pathogenesis in the Host Intestine

(2014) Moumita Mondal et al.   PLoS One

Enterotoxigenic Escherichia coli Secretes a Highly Conserved Mucin-Degrading Metalloprotease To Effectively Engage Intestinal Epithelial Cells

(2013) Qingwei Luo et al.   INFECTION AND IMMUNITY

Multiple Legionella pneumophila Type II Secretion Substrates, Including a Novel Protein, Contribute to Differential Infection of the Amoebae Acanthamoeba castellanii, Hartmannella vermiformis, and Naegleria lovaniensis

(2013) Jessica Y. Tyson et al.   INFECTION AND IMMUNITY

Bacterial chitinases and chitin-binding proteins as virulence factors

(2013) R. F. Frederiksen et al.   MICROBIOLOGY-SGM

Type II secretion: the substrates that won't go away

(2013) Arnaud Rondelet et al.   RESEARCH IN MICROBIOLOGY

The CRISPR-Associated Gene cas2 of Legionella pneumophila Is Required for Intracellular Infection of Amoebae

(2013) F. F. Gunderson et al.   mBio

Bacterial chitin degradation—mechanisms and ecophysiological strategies

(2013) Sara Beier et al.   Frontiers in Microbiology

Systematic Validation of Protein Force Fields against Experimental Data

(2012) Kresten Lindorff-Larsen et al.   PLoS One

Structural Insight into the Bacterial Mucinase StcE Essential to Adhesion and Immune Evasion during Enterohemorrhagic E. coli Infection

(2012) Angel C.Y. Yu et al.   STRUCTURE

Characterizing flexible and intrinsically unstructured biological macromolecules by SAS using the Porod-Debye law

(2011) Robert P. Rambo et al.   BIOPOLYMERS

Analysis of mucosal mucins separated by SDS-urea agarose polyacrylamide composite gel electrophoresis

(2011) Samah M. A. Issa et al.   ELECTROPHORESIS

Legionella pneumophila Type II Secretion Dampens the Cytokine Response of Infected Macrophages and Epithelia

(2011) Kessler McCoy-Simandle et al.   INFECTION AND IMMUNITY

Legionella pneumophila LbtU Acts as a Novel, TonB-Independent Receptor for the Legiobactin Siderophore

(2011) C. H. Chatfield et al.   JOURNAL OF BACTERIOLOGY

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Modulation of Host Cell Function byLegionella pneumophilaType IV Effectors

(2010) Andree Hubber et al.   Annual Review of Cell and Developmental Biology

New Pharmacotherapy for Airway Mucus Hypersecretion in Asthma and COPD: Targeting Intracellular Signaling Pathways

(2010) HonYee Lai et al.   Journal of Aerosol Medicine and Pulmonary Drug Delivery

Crystal Structures ofBacillus cereusNCTU2 Chitinase Complexes with Chitooligomers Reveal Novel Substrate Binding for Catalysis

(2010) Yin-Cheng Hsieh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dali server: conservation mapping in 3D

(2010) Liisa Holm et al.   NUCLEIC ACIDS RESEARCH

Measurement of wheat germ agglutinin binding with a fluorescence microscope

(2009) Michael A. Model et al.   CYTOMETRY PART A

xia2: an expert system for macromolecular crystallography data reduction

(2009) G. Winter   JOURNAL OF APPLIED CRYSTALLOGRAPHY

Metal active site elasticity linked to activation of homocysteine in methionine synthases

(2008) M. Koutmos et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA